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7OWD
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BU of 7owd by Molmil
Structure of CYLD CAP-Gly3 (467-552) bound to Ub; tetragonal space group
Descriptor: Ubiquitin, Ubiquitin carboxyl-terminal hydrolase CYLD
Authors:Elliott, P.R, Komander, D.
Deposit date:2021-06-17
Release date:2021-10-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains.
Cell Rep, 37, 2021
7OWC
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BU of 7owc by Molmil
Structure of CYLD CAP-Gly3 (467-565) bound to Ub; orthorhobic space group
Descriptor: Deubiquitinating enzyme CYLD, Ubiquitin-60S ribosomal protein L40
Authors:Elliott, P.R, Komander, D.
Deposit date:2021-06-17
Release date:2021-10-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains.
Cell Rep, 37, 2021
3PV1
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BU of 3pv1 by Molmil
Crystal structure of the USP15 DUSP-UBL domains
Descriptor: ACETATE ION, Ubiquitin carboxyl-terminal hydrolase 15
Authors:Elliott, P.R, Urbe, S, Clague, M.J, Barsukov, I.L.
Deposit date:2010-12-06
Release date:2011-11-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural variability of the ubiquitin specific protease DUSP-UBL double domains.
Febs Lett., 585, 2011
5LJM
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BU of 5ljm by Molmil
Structure of SPATA2 PUB domain
Descriptor: GLYCEROL, Spermatogenesis-associated protein 2
Authors:Elliott, P.R, Komander, D.
Deposit date:2016-07-18
Release date:2016-08-24
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.454 Å)
Cite:SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.
Mol.Cell, 63, 2016
5LJN
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BU of 5ljn by Molmil
Structure of the HOIP PUB domain bound to SPATA2 PIM peptide
Descriptor: E3 ubiquitin-protein ligase RNF31, GLYCEROL, SULFATE ION, ...
Authors:Elliott, P.R, Komander, D.
Deposit date:2016-07-18
Release date:2016-08-24
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.
Mol.Cell, 63, 2016
4OYJ
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BU of 4oyj by Molmil
Structure of the apo HOIP PUB domain
Descriptor: E3 ubiquitin-protein ligase RNF31, SULFATE ION
Authors:Elliott, P.R, Komander, D.
Deposit date:2014-02-12
Release date:2014-05-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular Basis and Regulation of OTULIN-LUBAC Interaction.
Mol.Cell, 54, 2014
4OYK
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BU of 4oyk by Molmil
Structure of HOIP PUB domain bound to OTULIN PIM
Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase RNF31, Ubiquitin thioesterase otulin
Authors:Elliott, P.R, Komander, D.
Deposit date:2014-02-12
Release date:2014-05-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.0001 Å)
Cite:Molecular Basis and Regulation of OTULIN-LUBAC Interaction.
Mol.Cell, 54, 2014
3IVF
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BU of 3ivf by Molmil
Crystal structure of the talin head FERM domain
Descriptor: Talin-1
Authors:Elliott, P.R, Goult, B.T, Bate, N, Grossmann, J.G, Roberts, G.C.K, Critchley, D.R, Barsukov, I.L.
Deposit date:2009-09-01
Release date:2010-08-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:The Structure of the talin head reveals a novel extended conformation of the FERM domain
Structure, 18, 2010
4A3P
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BU of 4a3p by Molmil
Structure of USP15 DUSP-UBL deletion mutant
Descriptor: ACETATE ION, IODIDE ION, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15
Authors:Elliott, P.R, Liu, H, Pastok, M.W, Grossmann, G.J, Rigden, D.J, Clague, M.J, Urbe, S, Barsukov, I.L.
Deposit date:2011-10-03
Release date:2011-11-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural Variability of the Ubiquitin Specific Protease Dusp-Ubl Double Domains.
FEBS Lett., 585, 2011
4A3O
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BU of 4a3o by Molmil
Crystal structure of the USP15 DUSP-UBL monomer
Descriptor: GLYCEROL, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15
Authors:Elliott, P.R, Liu, H, Pastok, M.W, Grossmann, G.J, Rigden, D.J, Clague, M.J, Urbe, S, Barsukov, I.L.
Deposit date:2011-10-03
Release date:2011-11-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Variability of the Ubiquitin Specific Protease Dusp-Ubl Double Domains.
FEBS Lett., 585, 2011
1QLP
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BU of 1qlp by Molmil
2.0 ANGSTROM STRUCTURE OF INTACT ALPHA-1-ANTITRYPSIN: A CANONICAL TEMPLATE FOR ACTIVE SERPINS
Descriptor: ALPHA-1-ANTITRYPSIN
Authors:Elliott, P.R, Pei, X.Y, Dafforn, T, Read, R.J, Carrell, R.W, Lomas, D.A.
Deposit date:1999-09-10
Release date:1999-09-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Topography of a 2.0 A structure of alpha1-antitrypsin reveals targets for rational drug design to prevent conformational disease.
Protein Sci., 9, 2000
5OE7
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BU of 5oe7 by Molmil
Structure of OTULIN bound to the Met1-linked diubiquitin activity probe
Descriptor: Polyubiquitin-C, Ubiquitin thioesterase otulin
Authors:Elliott, P.R, Komander, D.
Deposit date:2017-07-07
Release date:2017-09-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:A Linear Diubiquitin-Based Probe for Efficient and Selective Detection of the Deubiquitinating Enzyme OTULIN.
Cell Chem Biol, 24, 2017
6SAK
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BU of 6sak by Molmil
Structure of the OTULINcat C129A - SNX27 PDZ domain complex.
Descriptor: GLYCEROL, SULFATE ION, Sorting nexin-27, ...
Authors:Elliott, P.R, Komander, D.
Deposit date:2019-07-17
Release date:2019-10-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Regulation of the endosomal SNX27-retromer by OTULIN.
Nat Commun, 10, 2019
2LNK
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BU of 2lnk by Molmil
Solution structure of Ca-bound S100A4 in complex with non-muscle myosin IIA
Descriptor: Myosin heavy chain, non-muscle IIa, Protein S100-A4
Authors:Barsukov, I.L, Elliott, P.R.
Deposit date:2011-12-30
Release date:2012-04-25
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Asymmetric Mode of Ca(2+)-S100A4 Interaction with Nonmuscle Myosin IIA Generates Nanomolar Affinity Required for Filament Remodeling.
Structure, 20, 2012
1PSI
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BU of 1psi by Molmil
Intact recombined alpha1-antitrypsin mutant PHE 51 to LEU
Descriptor: ALPHA=1=-ANTITRYPSIN
Authors:Abrahams, J.P, Elliott, P.R, Lomas, D.A, Carrell, R.W.
Deposit date:1996-06-11
Release date:1996-12-07
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Inhibitory conformation of the reactive loop of alpha 1-antitrypsin.
Nat.Struct.Biol., 3, 1996
8P5P
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BU of 8p5p by Molmil
Structure of TECPR1 N-terminal DysF domain
Descriptor: GLYCEROL, Tectonin beta-propeller repeat-containing protein 1
Authors:Boyle, K.B, Elliott, P.R, Randow, F.
Deposit date:2023-05-24
Release date:2023-07-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:TECPR1 conjugates LC3 to damaged endomembranes upon detection of sphingomyelin exposure.
Embo J., 42, 2023
6I9C
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BU of 6i9c by Molmil
Structure of the OTU domain of OTULIN G281R mutant
Descriptor: CHLORIDE ION, GLYCEROL, Ubiquitin thioesterase otulin
Authors:Damgaard, R.B, Elliott, P.R, Swatek, K.N, Maher, E.R, Stepensky, P, Elpeleg, O, Komander, D, Berkun, Y.
Deposit date:2018-11-22
Release date:2019-03-06
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:OTULIN deficiency in ORAS causes cell type-specific LUBAC degradation, dysregulated TNF signalling and cell death.
Embo Mol Med, 11, 2019
8ATO
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BU of 8ato by Molmil
Structure of the giant inhibitor of apoptosis, BIRC6 bound to the regulator SMAC
Descriptor: Baculoviral IAP repeat-containing protein 6, Diablo IAP-binding mitochondrial protein
Authors:Dietz, L, Elliott, P.R.
Deposit date:2022-08-23
Release date:2023-03-08
Last modified:2023-03-29
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for SMAC-mediated antagonism of caspase inhibition by the giant ubiquitin ligase BIRC6.
Science, 379, 2023
8ATM
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BU of 8atm by Molmil
Structure of the giant inhibitor of apoptosis, BIRC6 (composite map)
Descriptor: Baculoviral IAP repeat-containing protein 6
Authors:Dietz, L, Elliott, P.R.
Deposit date:2022-08-23
Release date:2023-03-08
Last modified:2023-03-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for SMAC-mediated antagonism of caspase inhibition by the giant ubiquitin ligase BIRC6.
Science, 379, 2023
6YIE
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BU of 6yie by Molmil
Structure of a Borealin-INCENP-Survivin complex
Descriptor: Baculoviral IAP repeat-containing protein 5, Borealin, Inner centromere protein, ...
Authors:Serena, M, Elliott, P.R, Barr, F.A.
Deposit date:2020-04-01
Release date:2020-05-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Molecular basis of MKLP2-dependent Aurora B transport from chromatin to the anaphase central spindle.
J.Cell Biol., 219, 2020
6YIF
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BU of 6yif by Molmil
Structure of Chromosomal Passenger Complex (CPC) bound to phosphorylated Histone 3 peptide at 1.8 A.
Descriptor: Baculoviral IAP repeat-containing protein 5, Borealin, Inner centromere protein, ...
Authors:Serena, M, Elliott, P.R, Barr, F.A.
Deposit date:2020-04-01
Release date:2020-05-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Molecular basis of MKLP2-dependent Aurora B transport from chromatin to the anaphase central spindle.
J.Cell Biol., 219, 2020
6YIH
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BU of 6yih by Molmil
Structure of Chromosomal Passenger Complex (CPC) bound to phosphorylated Histone 3 peptide at 2.6 A.
Descriptor: Baculoviral IAP repeat-containing protein 5, Borealin, Histone H3.1, ...
Authors:Serena, M, Elliott, P.R, Barr, F.A.
Deposit date:2020-04-01
Release date:2020-05-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Molecular basis of MKLP2-dependent Aurora B transport from chromatin to the anaphase central spindle.
J.Cell Biol., 219, 2020
6YIP
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BU of 6yip by Molmil
Structure of MKLP2 coiled coil
Descriptor: ISOPROPYL ALCOHOL, Kinesin-like protein KIF20A
Authors:Serena, M, Elliott, P.R, Barr, F.A.
Deposit date:2020-04-01
Release date:2020-05-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Molecular basis of MKLP2-dependent Aurora B transport from chromatin to the anaphase central spindle.
J.Cell Biol., 219, 2020
5AF4
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BU of 5af4 by Molmil
Structure of Lys33-linked diUb
Descriptor: GLYCEROL, SULFATE ION, UBIQUITIN
Authors:Michel, M.A, Elliott, P.R, Swatek, K.N, Simicek, M, Pruneda, J.N, Wagstaff, J.L, Freund, S.M.V, Komander, D.
Deposit date:2015-01-19
Release date:2015-03-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Assembly and Specific Recognition of K29- and K33-Linked Polyubiquitin.
Mol.Cell, 58, 2015
5AF6
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BU of 5af6 by Molmil
Structure of Lys33-linked diUb bound to Trabid NZF1
Descriptor: TRABID, UBIQUITIN, ZINC ION
Authors:Michel, M.A, Elliott, P.R, Swatek, K.N, Simicek, M, Pruneda, J.N, Wagstaff, J.L, Freund, S.M.V, Komander, D.
Deposit date:2015-01-19
Release date:2015-03-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Assembly and Specific Recognition of K29- and K33-Linked Polyubiquitin.
Mol.Cell, 58, 2015

 

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