Author results

1HB1
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ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (ANAEROBIC ACOV FE COMPLEX)
Descriptor:ISOPENICILLIN N SYNTHASE, N6-[(1R)-2-{[(1R)-1-CARBOXY-2-METHYLPROPYL]OXY}-1-(MERCAPTOMETHYL)-2-OXOETHYL]-6-OXO-D-LYSINE, SULFATE ION, ...
Authors:Ogle, J.M., Clifton, I.J., Rutledge, P.J., Elkins, J.M., Burzlaff, N.I., Adlington, R.M., Roach, P.L., Baldwin, J.E.
Deposit date:2001-04-11
Release date:2001-11-23
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Alternative Oxidation by Isopenicillin N Synthase Observed by X-Ray Diffraction.
Chem.Biol., 8, 2001
1HB2
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ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (OXYGEN EXPOSED PRODUCT FROM ANAEROBIC ACOV FE COMPLEX)
Descriptor:ISOPENICILLIN N SYNTHASE, N6-[(1S)-2-{[(1R)-1-CARBOXY-2-METHYLPROPYL]OXY}-1-(MERCAPTOCARBONYL)-2-OXOETHYL]-6-OXO-L-LYSINE, SULFATE ION, ...
Authors:Ogle, J.M., Clifton, I.J., Rutledge, P.J., Elkins, J.M., Burzlaff, N.I., Adlington, R.M., Roach, P.L., Baldwin, J.E.
Deposit date:2001-04-11
Release date:2001-11-23
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Alternative Oxidation by Isopenicillin N Synthase Observed by X-Ray Diffraction.
Chem.Biol., 8, 2001
1HB3
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ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (OXYGEN EXPOSED PRODUCT FROM ANAEROBIC ACOV FE COMPLEX)
Descriptor:ISOPENICILLIN N SYNTHASE, N6-[(1S)-2-{[(1R)-1-CARBOXY-2-METHYLPROPYL]OXY}-1-(MERCAPTOCARBONYL)-2-OXOETHYL]-6-OXO-L-LYSINE, SULFATE ION, ...
Authors:Ogle, J.M., Clifton, I.J., Rutledge, P.J., Elkins, J.M., Burzlaff, N.I., Adlington, R.M., Roach, P.L., Baldwin, J.E.
Deposit date:2001-04-11
Release date:2001-11-23
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Alternative Oxidation by Isopenicillin N Synthase Observed by X-Ray Diffraction.
Chem.Biol., 8, 2001
1HB4
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ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (OXYGEN EXPOSED PRODUCT FROM ANAEROBIC ACOV FE COMPLEX)
Descriptor:ISOPENICILLIN N SYNTHASE, N6-[(1S)-2-{[(1R)-1-CARBOXY-2-METHYLPROPYL]OXY}-1-(MERCAPTOCARBONYL)-2-OXOETHYL]-6-OXO-L-LYSINE, SULFATE ION, ...
Authors:Ogle, J.M., Clifton, I.J., Rutledge, P.J., Elkins, J.M., Burzlaff, N.I., Adlington, R.M., Roach, P.L., Baldwin, J.E.
Deposit date:2001-04-11
Release date:2001-11-23
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Alternative Oxidation by Isopenicillin N Synthase Observed by X-Ray Diffraction.
Chem.Biol., 8, 2001
1GQW
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TAURINE/ALPHA-KETOGLUTARATE DIOXYGENASE FROM ESCHERICHIA COLI
Descriptor:ALPHA-KETOGLUTARATE-DEPENDENT TAURINE DIOXYGENASE, FE (II) ION, 2-AMINOETHANESULFONIC ACID, ...
Authors:Elkins, J.M., Ryle, M.J., Clifton, I.J., Dunning-Hotopp, J.C., Lloyd, J.S., Burzlaff, N.I., Baldwin, J.E., Hausinger, R.P., Roach, P.L.
Deposit date:2001-12-05
Release date:2002-04-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:X-Ray Crystal Structure of Escherichia Coli Taurine/Alpha-Ketoglutarate Dioxygenase Complexed to Ferrous Iron and Substrates
Biochemistry, 41, 2002
1GY9
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TAURINE/ALPHA-KETOGLUTARATE DIOXYGENASE FROM ESCHERICHIA COLI
Descriptor:ALPHA-KETOGLUTARATE-DEPENDENT TAURINE DIOXYGENASE, FE (III) ION, 2-AMINOETHANESULFONIC ACID, ...
Authors:Elkins, J.M., Burzlaff, N.I., Ryle, M.J., Lloyd, J.S., Clifton, I.J., Baldwin, J.E., Hausinger, R.P., Roach, P.L.
Deposit date:2002-04-22
Release date:2002-04-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:X-Ray Crystal Structure of Escherichia Coli Taurine/Alpha-Ketoglutarate Dioxygenase Complexed to Ferrous Iron and Substrates.
Biochemistry, 41, 2002
1GQ6
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PROCLAVAMINATE AMIDINO HYDROLASE FROM STREPTOMYCES CLAVULIGERUS
Descriptor:PROCLAVAMINATE AMIDINO HYDROLASE, MANGANESE (II) ION
Authors:Elkins, J.M., Clifton, I.J., Hernandez, H., Robinson, C.V., Schofield, C.J., Hewitson, K.S.
Deposit date:2001-11-20
Release date:2002-06-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Oligomeric Structure of Proclavaminic Acid Amidino Hydrolase: Evolution of a Hydrolytic Enzyme in Clavulanic Acid Biosynthesis
Biochem.J., 366, 2002
1GQ7
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PROCLAVAMINATE AMIDINO HYDROLASE FROM STREPTOMYCES CLAVULIGERUS
Descriptor:PROCLAVAMINATE AMIDINO HYDROLASE, MANGANESE (II) ION
Authors:Elkins, J.M., Clifton, I.J., Hernandez, H., Robinson, C.V., Schofield, C.J., Hewitson, K.S.
Deposit date:2001-11-20
Release date:2002-06-06
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Oligomeric structure of proclavaminic acid amidino hydrolase: evolution of a hydrolytic enzyme in clavulanic acid biosynthesis.
Biochem. J., 366, 2002
1H2K
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FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH HIF-1 ALPHA FRAGMENT PEPTIDE
Descriptor:FACTOR INHIBITING HIF1, HYPOXIA-INDUCIBLE FACTOR 1 ALPHA, FE (II) ION, ...
Authors:Elkins, J.M., Hewitson, K.S., McNeill, L.A., Schlemminger, I., Seibel, J.F., Schofield, C.J.
Deposit date:2002-08-12
Release date:2002-11-28
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure of Factor-Inhibiting Hypoxia-Inducible Factor (Hif) Reveals Mechanism of Oxidative Modification of Hif-1Alpha
J.Biol.Chem., 278, 2003
1H2L
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FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH HIF-1 ALPHA FRAGMENT PEPTIDE
Descriptor:FACTOR INHIBITING HIF1, HYPOXIA-INDUCIBLE FACTOR 1 ALPHA, FE (II) ION, ...
Authors:Elkins, J.M., Hewitson, K.S., McNeill, L.A., Schlemminger, I., Seibel, J.F., Schofield, C.J.
Deposit date:2002-08-12
Release date:2002-11-28
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure of Factor-Inhibiting Hypoxia-Inducible Factor (Hif) Reveals Mechanism of Oxidative Modification of Hif-1Alpha
J.Biol.Chem., 278, 2003
1H2M
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FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH HIF-1 ALPHA FRAGMENT PEPTIDE
Descriptor:FACTOR INHIBITING HIF1, HYPOXIA-INDUCIBLE FACTOR 1 ALPHA, ZINC ION, ...
Authors:Elkins, J.M., Hewitson, K.S., McNeill, L.A., Schlemminger, I., Seibel, J.F., Schofield, C.J.
Deposit date:2002-08-12
Release date:2002-11-28
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of Factor-Inhibiting Hypoxia-Inducible Factor (Hif) Reveals Mechanism of Oxidative Modification of Hif-1Alpha
J.Biol.Chem., 278, 2003
1H2N
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FACTOR INHIBITING HIF-1 ALPHA
Descriptor:HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR, FE (II) ION, 2-OXOGLUTARIC ACID, ...
Authors:Elkins, J.M., Hewitson, K.S., McNeill, L.A., Schlemminger, I., Seibel, J.F., Schofield, C.J.
Deposit date:2002-08-12
Release date:2002-11-28
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Structure of Factor-Inhibiting Hypoxia-Inducible Factor (Hif) Reveals Mechanism of Oxidative Modification of Hif-1Alpha
J.Biol.Chem., 278, 2003
1ODM
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ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (ANAEROBIC AC-VINYLGLYCINE FE COMPLEX)
Descriptor:ISOPENICILLIN N SYNTHASE, DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-D-VINYLGLYCINE, SULFATE ION, ...
Authors:Elkins, J.M., Rutledge, P.J., Burzlaff, N.I., Clifton, I.J., Adlington, R.M., Roach, P.L., Baldwin, J.E.
Deposit date:2003-02-19
Release date:2003-06-19
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Crystallographic Studies on the Reaction of Isopenicillin N Synthase with an Unsaturated Substrate Analogue
Org.Biomol.Chem., 1, 2003
1ODN
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ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (OXYGEN-EXPOSED PRODUCT FROM ANAEROBIC AC-VINYLGLYCINE FE COMPLEX)
Descriptor:ISOPENICILLIN N SYNTHASE, 6-(5-AMINO-5-CARBOXY-PENTANOYLAMINO)-3-HYDROXYMETHYL-7-OXO-4-THIA-1-AZA-BICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID, SULFATE ION, ...
Authors:Elkins, J.M., Rutledge, P.J., Burzlaff, N.I., Clifton, I.J., Adlington, R.M., Roach, P.L., Baldwin, J.E.
Deposit date:2003-02-19
Release date:2003-06-19
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystallographic Studies on the Reaction of Isopenicillin N Synthase with an Unsaturated Substrate Analogue
Org.Biomol.Chem., 1, 2003
1UPA
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CARBOXYETHYLARGININE SYNTHASE FROM STREPTOMYCES CLAVULIGERUS (SEMET STRUCTURE)
Descriptor:CARBOXYETHYLARGININE SYNTHASE, THIAMINE DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Caines, M.E.C., Elkins, J.M., Hewitson, K.S., Schofield, C.J.
Deposit date:2003-09-29
Release date:2003-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal Structure and Mechanistic Implications of N2-(2-Carboxyethyl)Arginine Synthase, the First Enzyme in the Clavulanic Acid Biosynthesis Pathway
J.Biol.Chem., 279, 2004
1UPB
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CARBOXYETHYLARGININE SYNTHASE FROM STREPTOMYCES CLAVULIGERUS
Descriptor:CARBOXYETHYLARGININE SYNTHASE, THIAMINE DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Caines, M.E.C., Elkins, J.M., Hewitson, K.S., Schofield, C.J.
Deposit date:2003-09-29
Release date:2003-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal Structure and Mechanistic Implications of N2-(2-Carboxyethyl)Arginine Synthase, the First Enzyme in the Clavulanic Acid Biosynthesis Pathway
J.Biol.Chem., 279, 2004
1UPC
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CARBOXYETHYLARGININE SYNTHASE FROM STREPTOMYCES CLAVULIGERUS
Descriptor:CARBOXYETHYLARGININE SYNTHASE, THIAMINE DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Caines, M.E.C., Elkins, J.M., Hewitson, K.S., Schofield, C.J.
Deposit date:2003-09-29
Release date:2003-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal Structure and Mechanistic Implications of N2-(2-Carboxyethyl)Arginine Synthase, the First Enzyme in the Clavulanic Acid Biosynthesis Pathway
J.Biol.Chem., 279, 2004
1VZ6
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ORNITHINE ACETYLTRANSFERASE (ORF6 GENE PRODUCT - CLAVULANIC ACID BIOSYNTHESIS) FROM STREPTOMYCES CLAVULIGERUS
Descriptor:ORNITHINE ACETYL-TRANSFERASE, SULFATE ION
Authors:Elkins, J.M., Kershaw, N.J., Schofield, C.J.
Deposit date:2004-05-14
Release date:2004-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:X-Ray Crystal Structure of Ornithine Acetyltransferase from the Clavulanic Acid Biosynthesis Gene Cluster.
Biochem.J., 385, 2005
1VZ7
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ORNITHINE ACETYLTRANSFERASE (ORF6 GENE PRODUCT - CLAVULANIC ACID BIOSYNTHESIS) FROM STREPTOMYCES CLAVULIGERUS
Descriptor:ORNITHINE ACETYL-TRANSFERASE, SULFATE ION
Authors:Elkins, J.M., Kershaw, N.J., Schofield, C.J.
Deposit date:2004-05-14
Release date:2004-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:X-Ray Crystal Structure of Ornithine Acetyltransferase from the Clavulanic Acid Biosynthesis Gene Cluster.
Biochem.J., 385, 2005
1VZ8
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ORNITHINE ACETYLTRANSFERASE (ORF6 GENE PRODUCT - CLAVULANIC ACID BIOSYNTHESIS) FROM STREPTOMYCES CLAVULIGERUS (SEMET STRUCTURE)
Descriptor:ORNITHINE ACETYL-TRANSFERASE, SULFATE ION
Authors:Elkins, J.M., Kershaw, N.J., Schofield, C.J.
Deposit date:2004-05-14
Release date:2004-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:X-Ray Crystal Structure of Ornithine Acetyltransferase from the Clavulanic Acid Biosynthesis Gene Cluster.
Biochem.J., 385, 2005
2BMJ
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GTPASE LIKE DOMAIN OF CENTAURIN GAMMA 1 (HUMAN)
Descriptor:CENTAURIN GAMMA 1
Authors:Yang, X., Elkins, J.M., Soundararajan, M., Arrowsmith, C., Edwards, A., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2005-03-14
Release date:2005-04-12
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Centaurin Gamma-1 Gtpase-Like Domain Functions as an Ntpase.
Biochem.J., 401, 2007
2BQ0
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14-3-3 PROTEIN BETA (HUMAN)
Descriptor:14-3-3 BETA/ALPHA
Authors:Yang, X., Elkins, J.M., Fedorov, O., Longman, E.J., Sobott, L., Ball, L.J., Sundstrom, M., Arrowsmith, C., Edwards, A., Doyle, D.A.
Deposit date:2005-04-26
Release date:2005-05-06
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Protein-Protein Interactions in the 14-3-3 Protein Family.
Proc.Natl.Acad.Sci.USA, 103, 2006
2BR9
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14-3-3 PROTEIN EPSILON (HUMAN) COMPLEXED TO PEPTIDE
Descriptor:14-3-3 PROTEIN EPSILON, CONSENSUS PEPTIDE FOR 14-3-3 PROTEINS
Authors:Yang, X., Elkins, J.M., Soundararajan, M., Fedorov, O., Sundstrom, M., Edwards, A., Arrowsmith, C., Doyle, D.A.
Deposit date:2005-05-03
Release date:2005-05-12
Last modified:2013-12-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Basis for Protein-Protein Interactions in the 14-3-3 Protein Family.
Proc.Natl.Acad.Sci.USA, 103, 2006
1YCI
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FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH N-(CARBOXYCARBONYL)-D-PHENYLALANINE
Descriptor:Hypoxia-inducible factor 1 alpha inhibitor, FE (II) ION, SULFATE ION, ...
Authors:McDonough, M.A., Schofield, C.J.
Deposit date:2004-12-22
Release date:2005-05-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Selective inhibition of factor inhibiting hypoxia-inducible factor
J.Am.Chem.Soc., 127, 2005
2BV1
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REGULATOR OF G-PROTEIN SIGNALLING 1 (HUMAN)
Descriptor:REGULATOR OF G-PROTEIN SIGNALLING 1
Authors:Elkins, J.M., Yang, X., Soundararajan, M., Schoch, G.A., Haroniti, A., Sundstrom, M., Edwards, A., Arrowsmith, C., Doyle, D.A.
Deposit date:2005-06-20
Release date:2005-06-27
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc. Natl. Acad. Sci. U.S.A., 105, 2008