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2B2X
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BU of 2b2x by Molmil
VLA1 RdeltaH I-domain complexed with a quadruple mutant of the AQC2 Fab
Descriptor: Antibody AQC2 Fab, Integrin alpha-1, MAGNESIUM ION
Authors:Clark, L.A, Boriack-Sjodin, P.A, Eldredge, J, Fitch, C, Friedman, B, Hanf, K.J, Jarpe, M, Liparoto, S.F, Li, Y, Lugovskoy, A.
Deposit date:2005-09-19
Release date:2006-04-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Affinity enhancement of an in vivo matured therapeutic antibody using structure-based computational design
Protein Sci., 15, 2006
3EOT
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BU of 3eot by Molmil
Crystal structure of LAC031, an engineered anti-VLA1 Fab
Descriptor: FAB FRAGMENT, HEAVY CHAIN, LIGHT CHAIN
Authors:Boriack-Sjodin, P.A, Clark, L.A.
Deposit date:2008-09-29
Release date:2009-01-20
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An antibody loop replacement design feasibility study and a loop-swapped dimer structure.
Protein Eng.Des.Sel., 22, 2009
3KYK
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BU of 3kyk by Molmil
Crystal structure of li33 Igg1 Fab
Descriptor: Heavy Chain Li33 IgG1, Light Chain Li33 IgG1, SULFATE ION
Authors:Silvian, L.F, Pepinsky, R.B, Walus, L.
Deposit date:2009-12-06
Release date:2010-03-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Improving the solubility of anti-LINGO-1 monoclonal antibody Li33 by isotype switching and targeted mutagenesis.
Protein Sci., 19, 2010
3KYM
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BU of 3kym by Molmil
Crystal structure of Li33 IgG2 di-Fab
Descriptor: Heavy Chain Li33 IgG2, Light Chain Li33 IgG2
Authors:Silvian, L.F, Pepinsky, R.B, Walus, L.
Deposit date:2009-12-06
Release date:2010-03-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Improving the solubility of anti-LINGO-1 monoclonal antibody Li33 by isotype switching and targeted mutagenesis.
Protein Sci., 19, 2010

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