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4BOP
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STRUCTURE OF OTUD1 OTU DOMAIN
Descriptor:OTU DOMAIN-CONTAINING PROTEIN 1, PHOSPHATE ION
Authors:Mevissen, T.E.T., Hospenthal, M.K., Geurink, P.P., Elliott, P.R., Akutsu, M., Arnaudo, N., Ekkebus, R., Kulathu, Y., Wauer, T., El Oualid, F., Freund, S.M.V., Ovaa, H., Komander, D.
Deposit date:2013-05-22
Release date:2013-07-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis.
Cell(Cambridge,Mass.), 154, 2013
4BOQ
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STRUCTURE OF OTUD2 OTU DOMAIN
Descriptor:UBIQUITIN THIOESTERASE OTU1, GLYCEROL
Authors:Mevissen, T.E.T., Hospenthal, M.K., Geurink, P.P., Elliott, P.R., Akutsu, M., Arnaudo, N., Ekkebus, R., Kulathu, Y., Wauer, T., El Oualid, F., Freund, S.M.V., Ovaa, H., Komander, D.
Deposit date:2013-05-22
Release date:2013-07-17
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis.
Cell(Cambridge,Mass.), 154, 2013
4BOS
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STRUCTURE OF OTUD2 OTU DOMAIN IN COMPLEX WITH UBIQUITIN K11-LINKED PEPTIDE
Descriptor:UBIQUITIN THIOESTERASE OTU1, POLYUBIQUITIN-C, OTUD2, ...
Authors:Mevissen, T.E.T., Hospenthal, M.K., Geurink, P.P., Elliott, P.R., Akutsu, M., Arnaudo, N., Ekkebus, R., Kulathu, Y., Wauer, T., El Oualid, F., Freund, S.M.V., Ovaa, H., Komander, D.
Deposit date:2013-05-22
Release date:2013-07-24
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis.
Cell(Cambridge,Mass.), 154, 2013
4BOU
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STRUCTURE OF OTUD3 OTU DOMAIN
Descriptor:OTU DOMAIN-CONTAINING PROTEIN 3
Authors:Mevissen, T.E.T., Hospenthal, M.K., Geurink, P.P., Elliott, P.R., Akutsu, M., Arnaudo, N., Ekkebus, R., Kulathu, Y., Wauer, T., El Oualid, F., Freund, S.M.V., Ovaa, H., Komander, D.
Deposit date:2013-05-22
Release date:2013-07-17
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis.
Cell(Cambridge,Mass.), 154, 2013
4BOZ
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STRUCTURE OF OTUD2 OTU DOMAIN IN COMPLEX WITH K11-LINKED DI UBIQUITIN
Descriptor:UBIQUITIN THIOESTERASE OTU1, UBIQUITIN-C, GLYCEROL
Authors:Mevissen, T.E.T., Hospenthal, M.K., Geurink, P.P., Elliott, P.R., Akutsu, M., Arnaudo, N., Ekkebus, R., Kulathu, Y., Wauer, T., El Oualid, F., Freund, S.M.V., Ovaa, H., Komander, D.
Deposit date:2013-05-22
Release date:2013-07-17
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis.
Cell(Cambridge,Mass.), 154, 2013
4UEL
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UCH-L5 IN COMPLEX WITH UBIQUITIN-PROPARGYL BOUND TO THE RPN13 DEUBAD DOMAIN
Descriptor:UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5, POLYUBIQUITIN-B, PROTEASOMAL UBIQUITIN RECEPTOR ADRM1
Authors:Sahtoe, D.D., Van Dijk, W.J., El Oualid, F., Ekkebus, R., Ovaa, H., Sixma, T.K.
Deposit date:2014-12-18
Release date:2015-03-04
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of Uch-L5 Activation and Inhibition by Deubad Domains in Rpn13 and Ino80G.
Mol.Cell, 57, 2015
4UEM
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UCH-L5 IN COMPLEX WITH THE RPN13 DEUBAD DOMAIN
Descriptor:UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5, PROTEASOMAL UBIQUITIN RECEPTOR ADRM1
Authors:Sahtoe, D.D., Van Dijk, W.J., El Oualid, F., Ekkebus, R., Ovaa, H., Sixma, T.K.
Deposit date:2014-12-18
Release date:2015-03-04
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Mechanism of Uch-L5 Activation and Inhibition by Deubad Domains in Rpn13 and Ino80G.
Mol.Cell, 57, 2015
4UF5
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CRYSTAL STRUCTURE OF UCH-L5 IN COMPLEX WITH INHIBITORY FRAGMENT OF INO80G
Descriptor:UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5, NUCLEAR FACTOR RELATED TO KAPPA-B-BINDING PROTEIN
Authors:Sahtoe, D.D., Van Dijk, W.J., El Oualid, F., Ekkebus, R., Ovaa, H., Sixma, T.K.
Deposit date:2014-12-23
Release date:2015-03-04
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Mechanism of Uch-L5 Activation and Inhibition by Deubad Domains in Rpn13 and Ino80G.
Mol.Cell, 57, 2015
4UF6
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UCH-L5 IN COMPLEX WITH UBIQUITIN-PROPARGYL BOUND TO AN ACTIVATING FRAGMENT OF INO80G
Descriptor:UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5, POLYUBIQUITIN-B, NUCLEAR FACTOR RELATED TO KAPPA-B-BINDING PROTEIN
Authors:Sahtoe, D.D., Van Dijk, W.J., El Oualid, F., Ekkebus, R., Ovaa, H., Sixma, T.K.
Deposit date:2014-12-23
Release date:2015-03-04
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.69 Å)
Cite:Mechanism of Uch-L5 Activation and Inhibition by Deubad Domains in Rpn13 and Ino80G.
Mol.Cell, 57, 2015
5LRU
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STRUCTURE OF CEZANNE/OTUD7B OTU DOMAIN
Descriptor:OTU domain-containing protein 7B
Authors:Mevissen, T.E.T., Kulathu, Y., Mulder, M.P.C., Geurink, P.P., Maslen, S.L., Gersch, M., Elliott, P.R., Burke, J.E., van Tol, B.D.M., Akutsu, M., El Oualid, F., Kawasaki, M., Freund, S.M.V., Ovaa, H., Komander, D.
Deposit date:2016-08-22
Release date:2016-10-19
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne.
Nature, 538, 2016
5LRV
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STRUCTURE OF CEZANNE/OTUD7B OTU DOMAIN BOUND TO LYS11-LINKED DIUBIQUITIN
Descriptor:OTU domain-containing protein 7B, Polyubiquitin-B, PHOSPHATE ION, ...
Authors:Mevissen, T.E.T., Kulathu, Y., Mulder, M.P.C., Geurink, P.P., Maslen, S.L., Gersch, M., Elliott, P.R., Burke, J.E., van Tol, B.D.M., Akutsu, M., El Oualid, F., Kawasaki, M., Freund, S.M.V., Ovaa, H., Komander, D.
Deposit date:2016-08-22
Release date:2016-10-19
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne.
Nature, 538, 2016
5LRW
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STRUCTURE OF CEZANNE/OTUD7B OTU DOMAIN BOUND TO UBIQUITIN
Descriptor:OTU domain-containing protein 7B, Polyubiquitin-B, GLYCEROL
Authors:Mevissen, T.E.T., Kulathu, Y., Mulder, M.P.C., Geurink, P.P., Maslen, S.L., Gersch, M., Elliott, P.R., Burke, J.E., van Tol, B.D.M., Akutsu, M., El Oualid, F., Kawasaki, M., Freund, S.M.V., Ovaa, H., Komander, D.
Deposit date:2016-08-22
Release date:2016-10-19
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne.
Nature, 538, 2016
5LRX
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STRUCTURE OF A20 OTU DOMAIN BOUND TO UBIQUITIN
Descriptor:Tumor necrosis factor alpha-induced protein 3, Polyubiquitin-B
Authors:Mevissen, T.E.T., Kulathu, Y., Mulder, M.P.C., Geurink, P.P., Maslen, S.L., Gersch, M., Elliott, P.R., Burke, J.E., van Tol, B.D.M., Akutsu, M., El Oualid, F., Kawasaki, M., Freund, S.M.V., Ovaa, H., Komander, D.
Deposit date:2016-08-22
Release date:2016-10-19
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne.
Nature, 538, 2016
5IFR
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STRUCTURE OF THE STABLE UBE2D3-UBDHA CONJUGATE
Descriptor:Ubiquitin-conjugating enzyme E2 D3, Polyubiquitin-B, GLYCEROL
Authors:Pruneda, J.N., Mulder, M.P.C., Witting, K., Ovaa, H., Komander, D.
Deposit date:2016-02-26
Release date:2016-05-11
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes.
Nat.Chem.Biol., 12, 2016
5OE7
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STRUCTURE OF OTULIN BOUND TO THE MET1-LINKED DIUBIQUITIN ACTIVITY PROBE
Descriptor:Ubiquitin thioesterase otulin, Polyubiquitin-C
Authors:Elliott, P.R., Komander, D.
Deposit date:2017-07-07
Release date:2017-09-27
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:A Linear Diubiquitin-Based Probe for Efficient and Selective Detection of the Deubiquitinating Enzyme OTULIN.
Cell Chem Biol, 24, 2017