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3P3K
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BU of 3p3k by Molmil
The crystal structure of translationally controlled tumor protein (TCTP) of Plasmodium falciparum
Descriptor: Translationally-controlled tumor protein homolog
Authors:Eichhorn, T, Winter, D, Dirdjaja, N, Frank, M, Krauth-Siegel, L, Granzin, J, Efferth, T.
Deposit date:2010-10-05
Release date:2011-11-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.551 Å)
Cite:Molecular interaction of artemisinin with translationally controlled tumor protein (TCTP) of Plasmodium falciparum.
Biochem Pharmacol, 85, 2013
8AU5
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BU of 8au5 by Molmil
c-MET F1200I mutant in complex with Tepotinib
Descriptor: 1,2-ETHANEDIOL, 3-[1-(3-{5-[(1-methylpiperidin-4-yl)methoxy]pyrimidin-2-yl}benzyl)-6-oxo-1,6-dihydropyridazin-3-yl]benzonitrile, CHLORIDE ION, ...
Authors:Graedler, U, Lammens, A.
Deposit date:2022-08-25
Release date:2023-09-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Biophysical and structural characterization of the impacts of MET phosphorylation on tepotinib binding.
J.Biol.Chem., 299, 2023
8AW1
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BU of 8aw1 by Molmil
c-MET Y1235D mutant in complex with Tepotinib
Descriptor: 3-[1-(3-{5-[(1-methylpiperidin-4-yl)methoxy]pyrimidin-2-yl}benzyl)-6-oxo-1,6-dihydropyridazin-3-yl]benzonitrile, Hepatocyte growth factor receptor
Authors:Graedler, U, Lammens, A.
Deposit date:2022-08-29
Release date:2023-09-06
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Biophysical and structural characterization of the impacts of MET phosphorylation on tepotinib binding.
J.Biol.Chem., 299, 2023
8AU3
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BU of 8au3 by Molmil
c-MET Y1234E,Y1235E mutant in complex with Tepotinib
Descriptor: 3-[1-(3-{5-[(1-methylpiperidin-4-yl)methoxy]pyrimidin-2-yl}benzyl)-6-oxo-1,6-dihydropyridazin-3-yl]benzonitrile, DI(HYDROXYETHYL)ETHER, Hepatocyte growth factor receptor, ...
Authors:Graedler, U, Lammens, A.
Deposit date:2022-08-25
Release date:2023-09-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Biophysical and structural characterization of the impacts of MET phosphorylation on tepotinib binding.
J.Biol.Chem., 299, 2023
6OMU
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BU of 6omu by Molmil
Structure of human Bruton's Tyrosine Kinase in complex with Evobrutinib
Descriptor: 1-[4-({[6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl]amino}methyl)piperidin-1-yl]prop-2-en-1-one, CHLORIDE ION, Tyrosine-protein kinase BTK
Authors:Mochalkin, I, Gardberg, A.S.
Deposit date:2019-04-19
Release date:2019-08-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Discovery of Evobrutinib: An Oral, Potent, and Highly Selective, Covalent Bruton's Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases.
J.Med.Chem., 62, 2019

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PDB entries from 2024-03-27

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