Author results

4A8D
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DEGP DODECAMER WITH BOUND OMP
Descriptor:PERIPLASMIC SERINE ENDOPROTEASE DEGP, OUTER MEMBRANE PROTEIN C
Authors:Malet, H., Krojer, T., Sawa, J., Schafer, E., Saibil, H.R., Ehrmann, M., Clausen, T.
Deposit date:2011-11-20
Release date:2012-01-11
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (28 Å)
Cite:Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq
Nat.Struct.Mol.Biol., 19, 2012
1KY9
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CRYSTAL STRUCTURE OF DEGP (HTRA)
Descriptor:PROTEASE DO
Authors:Krojer, T., Garrido-Franco, M., Huber, R., Ehrmann, M., Clausen, T.
Deposit date:2002-02-04
Release date:2002-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of DegP (HtrA) reveals a new protease-chaperone machine.
Nature, 416, 2002
3NUM
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SUBSTRATE INDUCED REMODELING OF THE ACTIVE SITE REGULATES HTRA1 ACTIVITY
Descriptor:Serine protease HTRA1
Authors:Truebestein, L., Tennstaedt, A., Hauske, P., Krojer, T., Kaiser, M., Clausen, T., Ehrmann, M.
Deposit date:2010-07-07
Release date:2011-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Substrate-induced remodeling of the active site regulates human HTRA1 activity.
Nat.Struct.Mol.Biol., 18, 2011
3NWU
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SUBSTRATE INDUCED REMODELING OF THE ACTIVE SITE REGULATES HTRA1 ACTIVITY
Descriptor:Serine protease HTRA1, SULFATE ION
Authors:Truebestein, L., Tennstaedt, A., Hauske, P., Krojer, T., Kaiser, M., Clausen, T., Ehrmann, M.
Deposit date:2010-07-11
Release date:2011-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Substrate-induced remodeling of the active site regulates human HTRA1 activity.
Nat.Struct.Mol.Biol., 18, 2011
3NZI
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SUBSTRATE INDUCED REMODELING OF THE ACTIVE SITE REGULATES HTRA1 ACTIVITY
Descriptor:Serine protease HTRA1, Citrate synthase
Authors:Truebestein, L., Tennstaedt, A., Hauske, P., Krojer, T., Kaiser, M., Clausen, T., Ehrmann, M.
Deposit date:2010-07-16
Release date:2011-02-23
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Substrate-induced remodeling of the active site regulates human HTRA1 activity.
Nat.Struct.Mol.Biol., 18, 2011
1SOT
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CRYSTAL STRUCTURE OF THE DEGS STRESS SENSOR
Descriptor:Protease degS
Authors:Wilken, C., Kitzing, K., Kurzbauer, R., Ehrmann, M., Clausen, T.
Deposit date:2004-03-15
Release date:2004-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease
Cell(Cambridge,Mass.), 117, 2004
1SOZ
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CRYSTAL STRUCTURE OF DEGS PROTEASE IN COMPLEX WITH AN ACTIVATING PEPTIDE
Descriptor:Protease degS, activating peptide
Authors:Wilken, C., Kitzing, K., Kurzbauer, R., Ehrmann, M., Clausen, T.
Deposit date:2004-03-16
Release date:2004-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease
Cell(Cambridge,Mass.), 117, 2004
1VCW
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CRYSTAL STRUCTURE OF DEGS AFTER BACKSOAKING THE ACTIVATING PEPTIDE
Descriptor:Protease degS
Authors:Wilken, C., Kitzing, K., Kurzbauer, R., Ehrmann, M., Clausen, T.
Deposit date:2004-03-16
Release date:2004-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease.
Cell(Cambridge,Mass.), 117, 2004
3CS0
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CRYSTAL STRUCTURE OF DEGP24
Descriptor:Periplasmic serine endoprotease DegP, pentapeptide
Authors:Krojer, T., Sawa, J., Schaefer, E., Saibil, H.R., Ehrmann, M., Clausen, T.
Deposit date:2008-04-08
Release date:2008-05-27
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for the regulated protease and chaperone function of DegP
Nature, 453, 2008
3STI
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CRYSTAL STRUCTURE OF THE PROTEASE DOMAIN OF DEGQ FROM ESCHERICHIA COLI
Descriptor:Protease degQ
Authors:Sawa, J., Malet, H., Krojer, T., Canellas, F., Ehrmann, M., Clausen, T.
Deposit date:2011-07-11
Release date:2011-07-27
Last modified:2012-01-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelope.
J.Biol.Chem., 286, 2011
3STJ
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CRYSTAL STRUCTURE OF THE PROTEASE + PDZ1 DOMAIN OF DEGQ FROM ESCHERICHIA COLI
Descriptor:Protease degQ, peptide (UNK)
Authors:Sawa, J., Malet, H., Krojer, T., Canellas, F., Ehrmann, M., Clausen, T.
Deposit date:2011-07-11
Release date:2011-07-27
Last modified:2012-01-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelope.
J.Biol.Chem., 286, 2011
4A8A
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ASYMMETRIC CRYO-EM RECONSTRUCTION OF E. COLI DEGQ 12-MER IN COMPLEX WITH LYSOZYME
Descriptor:PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ, LYSOZYME C
Authors:Malet, H., Canellas, F., Sawa, J., Yan, J., Thalassinos, K., Ehrmann, M., Clausen, T., Saibil, H.R.
Deposit date:2011-11-20
Release date:2011-12-28
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (14.2 Å)
Cite:Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq
Nat.Struct.Mol.Biol., 19, 2012
4A8B
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SYMMETRIZED CRYO-EM RECONSTRUCTION OF E. COLI DEGQ 12-MER IN COMPLEX WITH LYSOZYMES
Descriptor:PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ, LYSOZYME C
Authors:Malet, H., Canellas, F., Sawa, J., Yan, J., Thalassinos, K., Ehrmann, M., Clausen, T., Saibil, H.R.
Deposit date:2011-11-20
Release date:2012-01-11
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (13 Å)
Cite:Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq
Nat.Struct.Mol.Biol., 19, 2012
4A8C
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SYMMETRIZED CRYO-EM RECONSTRUCTION OF E. COLI DEGQ 12-MER IN COMPLEX WITH A BINDING PEPTIDE
Descriptor:PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ
Authors:Malet, H., Canellas, F., Sawa, J., Yan, J., Thalassinos, K., Ehrmann, M., Clausen, T., Saibil, H.R.
Deposit date:2011-11-20
Release date:2012-01-11
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq
Nat.Struct.Mol.Biol., 19, 2012
4A9G
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SYMMETRIZED CRYO-EM RECONSTRUCTION OF E. COLI DEGQ 24-MER IN COMPLEX WITH BETA-CASEIN
Descriptor:PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ
Authors:Malet, H., Canellas, F., Sawa, J., Yan, J., Thalassinos, K., Ehrmann, M., Clausen, T., Saibil, H.R.
Deposit date:2011-11-26
Release date:2012-01-11
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq
Nat.Struct.Mol.Biol., 19, 2012
4C2C
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CRYSTAL STRUCTURE OF THE PROTEASE CTPB IN AN ACTIVE STATE
Descriptor:CARBOXY-TERMINAL PROCESSING PROTEASE CTPB, PEPTIDE1, PEPTIDE2
Authors:Mastny, M., Heuck, A., Kurzbauer, R., Clausen, T.
Deposit date:2013-08-17
Release date:2013-12-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis.
Cell(Cambridge,Mass.), 155, 2013
4C2D
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CRYSTAL STRUCTURE OF THE PROTEASE CTPB IN AN ACTIVE STATE
Descriptor:CARBOXY-TERMINAL PROCESSING PROTEASE CTPB, PEPTIDE1, PEPTIDE2
Authors:Mastny, M., Heuck, A., Kurzbauer, R., Clausen, T.
Deposit date:2013-08-17
Release date:2013-12-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis.
Cell(Cambridge,Mass.), 155, 2013
4C2E
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CRYSTAL STRUCTURE OF THE PROTEASE CTPB(S309A) PRESENT IN A RESTING STATE
Descriptor:CARBOXY-TERMINAL PROCESSING PROTEASE CTPB
Authors:Mastny, M., Heuck, A., Kurzbauer, R., Clausen, T.
Deposit date:2013-08-17
Release date:2013-12-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis.
Cell(Cambridge,Mass.), 155, 2013
4C2F
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CRYSTAL STRUCTURE OF THE CTPB R168A MUTANT PRESENT IN AN ACTIVE CONFORMATION
Descriptor:CARBOXY-TERMINAL PROCESSING PROTEASE CTPB, PEPTIDE1, PEPTIDE2
Authors:Mastny, M., Heuck, A., Kurzbauer, R., Clausen, T.
Deposit date:2013-08-17
Release date:2013-12-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis.
Cell(Cambridge,Mass.), 155, 2013
4C2G
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CRYSTAL STRUCTURE OF CTPB(S309A) IN COMPLEX WITH A PEPTIDE HAVING A VAL-PRO-ALA C-TERMINUS
Descriptor:CARBOXY-TERMINAL PROCESSING PROTEASE CTPB, PEPTIDE1
Authors:Mastny, M., Heuck, A., Kurzbauer, R., Clausen, T.
Deposit date:2013-08-17
Release date:2013-12-04
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis.
Cell(Cambridge,Mass.), 155, 2013
4C2H
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CRYSTAL STRUCTURE OF THE CTPB(V118Y) MUTANT
Descriptor:CARBOXY-TERMINAL PROCESSING PROTEASE CTPB
Authors:Mastny, M., Heuck, A., Kurzbauer, R., Clausen, T.
Deposit date:2013-08-17
Release date:2013-12-04
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis.
Cell(Cambridge,Mass.), 155, 2013
6EW9
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CRYSTAL STRUCTURE OF DEGS STRESS SENSOR PROTEASE IN COMPLEX WITH ACTIVATING DNRLGLVYQF PEPTIDE
Descriptor:Serine endoprotease DegS, DNRLGLVYQF PEPTIDE, DI(HYDROXYETHYL)ETHER, ...
Authors:Vetter, I.R., Porfetye, A.T., Stege, P.
Deposit date:2017-11-03
Release date:2018-04-25
Last modified:2018-11-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Identification of Noncatalytic Lysine Residues from Allosteric Circuits via Covalent Probes.
ACS Chem. Biol., 13, 2018
2R3U
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CRYSTAL STRUCTURE OF THE PDZ DELETION MUTANT OF DEGS
Descriptor:Protease degS
Authors:Clausen, T., Kurzbauer, R.
Deposit date:2007-08-30
Release date:2007-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Regulation of the sigmaE stress response by DegS: how the PDZ domain keeps the protease inactive in the resting state and allows integration of different OMP-derived stress signals upon folding stress.
Genes Dev., 21, 2007
2R3Y
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CRYSTAL STRUCTURE OF THE DEGS PROTEASE IN COMPLEX WITH THE YWF ACTIVATING PEPTIDE
Descriptor:Protease degS, Synthetic peptide YWF
Authors:Clausen, T., Hasselblatt, H.
Deposit date:2007-08-30
Release date:2007-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Regulation of the sigmaE stress response by DegS: how the PDZ domain keeps the protease inactive in the resting state and allows integration of different OMP-derived stress signals upon folding stress.
Genes Dev., 21, 2007
2ZLE
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CRYO-EM STRUCTURE OF DEGP12/OMP
Descriptor:Protease do, Outer membrane protein C
Authors:Schaefer, E., Saibil, H.R.
Deposit date:2008-04-09
Release date:2008-06-03
Last modified:2017-02-08
Method:ELECTRON MICROSCOPY (28 Å)
Cite:Structural basis for the regulated protease and chaperone function of DegP
Nature, 453, 2008
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