Author results

3BDJ
  • Download 3bdj
  • View 3bdj
Molmil generated image of 3bdj
CRYSTAL STRUCTURE OF BOVINE MILK XANTHINE DEHYDROGENASE WITH A COVALENTLY BOUND OXIPURINOL INHIBITOR
Descriptor:Xanthine dehydrogenase/oxidase, CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Eger, B.T., Okamoto, K., Nishino, T., Pai, E.F., Nishino, T.
Deposit date:2007-11-14
Release date:2008-11-25
Last modified:2014-09-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mechanism of inhibition of xanthine oxidoreductase by allopurinol: crystal structure of reduced bovine milk xanthine oxidoreductase bound with oxipurinol.
Nucleosides Nucleotides Nucleic Acids, 27, 2008
3UNA
  • Download 3una
  • View 3una
Molmil generated image of 3una
CRYSTAL STRUCTURE OF BOVINE MILK XANTHINE DEHYDROGENASE WITH NAD BOUND
Descriptor:Xanthine dehydrogenase/oxidase, FE2/S2 (INORGANIC) CLUSTER, PHOSPHONIC ACIDMONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,7,8A,9,10,10A-HEXAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL)ESTER, ...
Authors:Eger, B.T., Okamoto, K., Nishino, T., Pai, E.F.
Deposit date:2011-11-15
Release date:2012-05-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Protein conformational gating of enzymatic activity in xanthine oxidoreductase.
J.Am.Chem.Soc., 134, 2012
3UNC
  • Download 3unc
  • View 3unc
Molmil generated image of 3unc
CRYSTAL STRUCTURE OF BOVINE MILK XANTHINE DEHYDROGENASE TO 1.65A RESOLUTION
Descriptor:Xanthine dehydrogenase/oxidase, FE2/S2 (INORGANIC) CLUSTER, PHOSPHONIC ACIDMONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,7,8A,9,10,10A-HEXAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL)ESTER, ...
Authors:Eger, B.T., Okamoto, K., Nishino, T., Pai, E.F.
Deposit date:2011-11-15
Release date:2012-05-09
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Protein conformational gating of enzymatic activity in xanthine oxidoreductase.
J.Am.Chem.Soc., 134, 2012
3UNI
  • Download 3uni
  • View 3uni
Molmil generated image of 3uni
CRYSTAL STRUCTURE OF BOVINE MILK XANTHINE DEHYDROGENASE WITH NADH BOUND
Descriptor:Xanthine dehydrogenase/oxidase, FE2/S2 (INORGANIC) CLUSTER, PHOSPHONIC ACIDMONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,7,8A,9,10,10A-HEXAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL)ESTER, ...
Authors:Eger, B.T., Okamoto, K., Nishino, T., Pai, E.F.
Deposit date:2011-11-15
Release date:2012-05-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Protein conformational gating of enzymatic activity in xanthine oxidoreductase.
J.Am.Chem.Soc., 134, 2012
6BK9
  • Download 6bk9
  • View 6bk9
Molmil generated image of 6bk9
CRYSTAL STRUCTURE OF SQUID ARRESTIN
Descriptor:Visual arrestin, CHLORIDE ION
Authors:Eger, B.T., Bandyopadhyay, A., Yedidi, R.S., Ernst, O.P.
Deposit date:2017-11-08
Release date:2018-09-19
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (3.000056 Å)
Cite:A Novel Polar Core and Weakly Fixed C-Tail in Squid Arrestin Provide New Insight into Interaction with Rhodopsin.
J. Mol. Biol., 430, 2018
1AV7
  • Download 1av7
  • View 1av7
Molmil generated image of 1av7
SUBTILISIN CARLSBERG L-NAPHTHYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX
Descriptor:SUBTILISIN CARLSBERG, TYPE VIII, SODIUM ION
Authors:Stoll, V.S., Eger, B.T., Hynes, R.C., Martichonok, V., Jones, J.B., Pai, E.F.
Deposit date:1997-09-29
Release date:1998-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes.
Biochemistry, 37, 1998
1AVT
  • Download 1avt
  • View 1avt
Molmil generated image of 1avt
SUBTILISIN CARLSBERG D-PARA-CHLOROPHENYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX
Descriptor:SUBTILISIN CARLSBERG, TYPE VIII, SODIUM ION
Authors:Stoll, V.S., Eger, B.T., Hynes, R.C., Martichonok, V., Jones, J.B., Pai, E.F.
Deposit date:1997-09-19
Release date:1998-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes.
Biochemistry, 37, 1998
1FIQ
  • Download 1fiq
  • View 1fiq
Molmil generated image of 1fiq
CRYSTAL STRUCTURE OF XANTHINE OXIDASE FROM BOVINE MILK
Descriptor:XANTHINE OXIDASE, FE2/S2 (INORGANIC) CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Enroth, C., Eger, B.T., Okamoto, K., Nishino, T., Nishino, T., Pai, E.F.
Deposit date:2000-08-04
Release date:2000-10-04
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of bovine milk xanthine dehydrogenase and xanthine oxidase: structure-based mechanism of conversion.
Proc.Natl.Acad.Sci.USA, 97, 2000
1FO4
  • Download 1fo4
  • View 1fo4
Molmil generated image of 1fo4
CRYSTAL STRUCTURE OF XANTHINE DEHYDROGENASE ISOLATED FROM BOVINE MILK
Descriptor:XANTHINE DEHYDROGENASE, CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Enroth, C., Eger, B.T., Okamoto, K., Nishino, T., Nishino, T., Pai, E.F.
Deposit date:2000-08-24
Release date:2000-10-25
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of bovine milk xanthine dehydrogenase and xanthine oxidase: structure-based mechanism of conversion.
Proc.Natl.Acad.Sci.USA, 97, 2000
1N5X
  • Download 1n5x
  • View 1n5x
Molmil generated image of 1n5x
XANTHINE DEHYDROGENASE FROM BOVINE MILK WITH INHIBITOR TEI-6720 BOUND
Descriptor:Xanthine Dehydrogenase, FE2/S2 (INORGANIC) CLUSTER, PHOSPHONIC ACIDMONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,7,8A,9,10,10A-HEXAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL)ESTER, ...
Authors:Okamoto, K., Eger, B.T., Nishino, T., Kondo, S., Pai, E.F., Nishino, T.
Deposit date:2002-11-07
Release date:2003-03-18
Last modified:2013-05-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:An Extremely Potent Inhibitor of Xanthine Oxidoreductase: Crystal Structure of the Enzyme-Inhibitor Complex and Mechanism of Inhibition
J.BIOL.CHEM., 278, 2003
1V97
  • Download 1v97
  • View 1v97
Molmil generated image of 1v97
CRYSTAL STRUCTURE OF BOVINE MILK XANTHINE DEHYDROGENASE FYX-051 BOUND FORM
Descriptor:Xanthine dehydrogenase, CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Okamoto, K., Matsumoto, K., Hille, R., Eger, B.T., Pai, E.F., Nishino, T.
Deposit date:2004-01-21
Release date:2004-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:The crystal structure of xanthine oxidoreductase during catalysis: Implications for reaction mechanism and enzyme inhibition.
Proc.Natl.Acad.Sci.USA, 101, 2004
1VDV
  • Download 1vdv
  • View 1vdv
Molmil generated image of 1vdv
BOVINE MILK XANTHINE DEHYDROGENASE Y-700 BOUND FORM
Descriptor:Xanthine dehydrogenase/oxidase, CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Fukunari, A., Okamoto, K., Nishino, T., Eger, B.T., Pai, E.F., Kamezawa, M., Yamada, I., Kato, N.
Deposit date:2004-03-25
Release date:2004-12-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Y-700 [1-[3-Cyano-4-(2,2-dimethylpropoxy)phenyl]-1H-pyrazole-4-carboxylic acid]: a potent xanthine oxidoreductase inhibitor with hepatic excretion
J.Pharmacol.Exp.Ther., 311, 2004
1VGC
  • Download 1vgc
  • View 1vgc
Molmil generated image of 1vgc
GAMMA-CHYMOTRYPSIN L-PARA-CHLORO-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX
Descriptor:GAMMA CHYMOTRYPSIN, SULFATE ION, L-1-(4-CHLOROPHENYL)-2-(ACETAMIDO)ETHANE BORONIC ACID
Authors:Stoll, V.S., Eger, B.T., Hynes, R.C., Martichonok, V., Jones, J.B., Pai, E.F.
Deposit date:1997-05-01
Release date:1997-11-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes.
Biochemistry, 37, 1998
1VSB
  • Download 1vsb
  • View 1vsb
Molmil generated image of 1vsb
SUBTILISIN CARLSBERG L-PARA-CHLOROPHENYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX
Descriptor:SUBTILISIN CARLSBERG, TYPE VIII
Authors:Stoll, V.S., Eger, B.T., Hynes, R.C., Martichonok, V., Jones, J.B., Pai, E.F.
Deposit date:1997-09-17
Release date:1998-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes.
Biochemistry, 37, 1998
1WYG
  • Download 1wyg
  • View 1wyg
Molmil generated image of 1wyg
CRYSTAL STRUCTURE OF A RAT XANTHINE DEHYDROGENASE TRIPLE MUTANT (C535A, C992R AND C1324S)
Descriptor:Xanthine dehydrogenase/oxidase, PHOSPHATE ION, CALCIUM ION, ...
Authors:Nishino, T., Okamoto, K., Kawaguchi, Y., Hori, H., Matsumura, T., Eger, B.T., Pai, E.F., Nishino, T.
Deposit date:2005-02-14
Release date:2005-05-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Mechanism of the Conversion of Xanthine Dehydrogenase to Xanthine Oxidase: IDENTIFICATION OF THE TWO CYSTEINE DISULFIDE BONDS AND CRYSTAL STRUCTURE OF A NON-CONVERTIBLE RAT LIVER XANTHINE DEHYDROGENASE MUTANT
J.Biol.Chem., 280, 2005
2VGC
  • Download 2vgc
  • View 2vgc
Molmil generated image of 2vgc
GAMMA-CHYMOTRYPSIN D-PARA-CHLORO-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX
Descriptor:GAMMA CHYMOTRYPSIN, SULFATE ION, D-1-(4-CHLOROPHENYL)-2-(ACETAMIDO)ETHANE BORONIC ACID
Authors:Stoll, V.S., Eger, B.T., Hynes, R.C., Martichonok, V., Jones, J.B., Pai, E.F.
Deposit date:1997-05-01
Release date:1997-11-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes.
Biochemistry, 37, 1998
3AMZ
  • Download 3amz
  • View 3amz
Molmil generated image of 3amz
BOVINE XANTHINE OXIDOREDUCTASE URATE BOUND FORM
Descriptor:Xanthine dehydrogenase/oxidase, FE2/S2 (INORGANIC) CLUSTER, CALCIUM ION, ...
Authors:Okamoto, K., Eger, B.T., Pai, E.F., Nishino, T.
Deposit date:2010-08-27
Release date:2010-12-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of Urate Bound Form of Xanthine Oxidoreductase: Substrate Orientation and Structure of the Key Reaction Intermediate
J.Am.Chem.Soc., 132, 2010
3AN1
  • Download 3an1
  • View 3an1
Molmil generated image of 3an1
CRYSTAL STRUCTURE OF RAT D428A MUTANT, URATE BOUND FORM
Descriptor:Xanthine dehydrogenase/oxidase, FE2/S2 (INORGANIC) CLUSTER, CALCIUM ION, ...
Authors:Okamoto, K., Kawaguchi, Y., Eger, B.T., Pai, E.F., Nishino, T.
Deposit date:2010-08-27
Release date:2010-12-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Crystal Structures of Urate Bound Form of Xanthine Oxidoreductase: Substrate Orientation and Structure of the Key Reaction Intermediate
J.Am.Chem.Soc., 132, 2010
3AX7
  • Download 3ax7
  • View 3ax7
Molmil generated image of 3ax7
BOVINE XANTHINE OXIDASE, PROTEASE CLEAVED FORM
Descriptor:Xanthine dehydrogenase/oxidase, FE2/S2 (INORGANIC) CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Ishikita, H., Eger, B.T., Pai, E.F., Okamoto, K., Nishino, T.
Deposit date:2011-03-30
Release date:2012-02-22
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Protein conformational gating of enzymatic activity in xanthine oxidoreductase
J.Am.Chem.Soc., 134, 2012
3AX9
  • Download 3ax9
  • View 3ax9
Molmil generated image of 3ax9
BOVINE XANTHINE OXIDASE, PROTEASE CLEAVED FORM
Descriptor:Xanthine dehydrogenase/oxidase, FE2/S2 (INORGANIC) CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Ishikita, H., Eger, B.T., Pai, E.F., Okamoto, K., Nishino, T.
Deposit date:2011-03-31
Release date:2012-02-22
Last modified:2013-09-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Protein conformational gating of enzymatic activity in xanthine oxidoreductase
J.Am.Chem.Soc., 134, 2012
3VGC
  • Download 3vgc
  • View 3vgc
Molmil generated image of 3vgc
GAMMA-CHYMOTRYPSIN L-NAPHTHYL-1-ACETAMIDO BORONIC ACID ACID INHIBITOR COMPLEX
Descriptor:GAMMA CHYMOTRYPSIN, SULFATE ION, L-1-NAPHTHYL-2-ACETAMIDO-ETHANE BORONIC ACID
Authors:Stoll, V.S., Eger, B.T., Hynes, R.C., Martichonok, V., Jones, J.B., Pai, E.F.
Deposit date:1997-05-01
Release date:1997-11-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes.
Biochemistry, 37, 1998
3VSB
  • Download 3vsb
  • View 3vsb
Molmil generated image of 3vsb
SUBTILISIN CARLSBERG D-NAPHTHYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX
Descriptor:SUBTILISIN CARLSBERG, TYPE VIII, SODIUM ION
Authors:Stoll, V.S., Eger, B.T., Hynes, R.C., Martichonok, V., Jones, J.B., Pai, E.F.
Deposit date:1997-09-25
Release date:1998-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes.
Biochemistry, 37, 1998
4VGC
  • Download 4vgc
  • View 4vgc
Molmil generated image of 4vgc
GAMMA-CHYMOTRYPSIN D-NAPHTHYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX
Descriptor:GAMMA CHYMOTRYPSIN, SULFATE ION, D-1-NAPHTHYL-2-ACETAMIDO-ETHANE BORONIC ACID
Authors:Stoll, V.S., Eger, B.T., Hynes, R.C., Martichonok, V., Jones, J.B., Pai, E.F.
Deposit date:1997-05-01
Release date:1997-11-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes.
Biochemistry, 37, 1998
4YSW
  • Download 4ysw
  • View 4ysw
Molmil generated image of 4ysw
STRUCTURE OF RAT XANTHINE OXIDOREDUCTASE, C-TERMINAL DELETION PROTEIN VARIANT, NADH BOUND FORM
Descriptor:Xanthine dehydrogenase/oxidase, FE2/S2 (INORGANIC) CLUSTER, CALCIUM ION, ...
Authors:Nishino, T., Okamoto, K., Kawaguchi, Y., Matsumura, T., Eger, B.T., Pai, E.F.
Deposit date:2015-03-17
Release date:2015-04-22
Last modified:2015-09-09
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:The C-terminal peptide plays a role in the formation of an intermediate form during the transition between xanthine dehydrogenase and xanthine oxidase.
Febs J., 282, 2015
4YTY
  • Download 4yty
  • View 4yty
Molmil generated image of 4yty
STRUCTURE OF RAT XANTHINE OXIDOREDUCTASE, C535A/C992R/C1324S, NADH BOUND FORM
Descriptor:Xanthine dehydrogenase/oxidase, FE2/S2 (INORGANIC) CLUSTER, CALCIUM ION, ...
Authors:Nishino, T., Okamoto, K., Kawaguchi, Y., Matsumura, T., Eger, B.T., Pai, E.F.
Deposit date:2015-03-18
Release date:2015-04-22
Last modified:2015-09-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The C-terminal peptide plays a role in the formation of an intermediate form during the transition between xanthine dehydrogenase and xanthine oxidase.
Febs J., 282, 2015
<12>