Author results

1DHM
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DNA-BINDING DOMAIN OF E2 FROM HUMAN PAPILLOMAVIRUS-31, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称:E2 PROTEIN
著者Liang, H., Petros, A.P., Meadows, R.P., Yoon, H.S., Egan, D.A., Walter, K., Holzman, T.F., Robins, T., Fesik, S.W.
登録日1995-08-15
公開日1996-12-07
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of the DNA-binding domain of a human papillomavirus E2 protein: evidence for flexible DNA-binding regions.
Biochemistry, 35, 1996
2JIX
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CRYSTAL STRUCTURE OF ABT-007 FAB FRAGMENT WITH THE SOLUBLE DOMAIN OF EPO RECEPTOR
分子名称:ABT-007 FAB FRAGMENT, ERYTHROPOIETIN RECEPTOR
著者Liu, Z., Stoll, V.S., DeVries, P., Jakob, C.G., Xie, N., Simmer, R.L., Lacy, S.E., Egan, D.A., Harlan, J.E., Lesniewski, R.R., Reilly, E.B.
登録日2007-07-02
公開日2007-07-10
最終更新日2013-10-30
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献A Potent Erythropoietin-Mimicking Human Antibody Interacts Through a Novel Binding Site.
Blood, 110, 2007
1A7G
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THE CRYSTAL STRUCTURE OF THE E2 DNA-BINDING DOMAIN FROM HUMAN PAPILLOMAVIRUS AT 2.4 ANGSTROMS
分子名称:REGULATORY PROTEIN E2, SULFATE ION
著者Bussiere, D.E., Giranda, V.L.
登録日1998-03-13
公開日1999-04-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the E2 DNA-binding domain from human papillomavirus serotype 31 at 2.4 A.
Acta Crystallogr.,Sect.D, 54, 1998
1CYA
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NMR STUDIES OF (U-13C)CYCLOSPORIN A BOUND TO CYCLOPHILIN: BOUND CONFORMATION AND PORTIONS OF CYCLOSPORIN INVOLVED IN BINDING
分子名称:CYCLOSPORIN A
著者Fesik, S.W.
登録日1992-02-24
公開日1994-01-31
最終更新日2012-12-12
実験手法SOLUTION NMR
主引用文献NMR Studies of [U-13C]Cyclosporin a Bound to Cyclophilin: Bound Conformation and Portions of Cyclosporin Involved in Binding.
Biochemistry, 30, 1991
1CYB
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NMR STUDIES OF (U-13C)CYCLOSPORIN A BOUND TO CYCLOPHILIN: BOUND CONFORMATION AND PORTIONS OF CYCLOSPORIN INVOLVED IN BINDING
分子名称:CYCLOSPORIN A
著者Fesik, S.W.
登録日1992-02-24
公開日1994-01-31
最終更新日2012-12-12
実験手法SOLUTION NMR
主引用文献NMR Studies of [U-13C]Cyclosporin a Bound to Cyclophilin: Bound Conformation and Portions of Cyclosporin Involved in Binding.
Biochemistry, 30, 1991
6E99
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CRYSTAL STRUCTURE OF PROTEIN KINASE A IN COMPLEX WITH THE PKI PEPTIDE AND AN AMINO-PYRIDINYLBENZAMIDE BASED INHIBITOR.
分子名称:cAMP-dependent protein kinase catalytic subunit alpha, PKI peptide, 2-[(2-aminoethyl)amino]-N-[(1R)-1-(3-methoxyphenyl)ethyl]-4-(pyridin-4-yl)benzamide
著者Judge, R.A., Hobson, A.D.
登録日2018-07-31
公開日2018-11-14
最終更新日2019-01-16
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure Based Drug Design.
J. Med. Chem., 61, 2018
6E9L
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CRYSTAL STRUCTURE OF PROTEIN KINASE A IN COMPLEX WITH THE PKI PEPTIDE AND A PYRIDINYLBENZAMIDE BASED INHIBITOR
分子名称:cAMP-dependent protein kinase catalytic subunit alpha, PKI peptide, N-[(2,3-dihydro-1,4-benzodioxin-5-yl)methyl]-4-(pyridin-4-yl)benzamide
著者Judge, R.A., Hobson, A.D.
登録日2018-08-01
公開日2018-11-14
最終更新日2019-01-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure Based Drug Design.
J. Med. Chem., 61, 2018
6E9W
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CRYSTAL STRUCTURE OF ROCK1 WITH A PYRIDINYLBENZAMIDE BASED INHIBITOR
分子名称:Rho-associated protein kinase 1, N-[(2,3-dihydro-1,4-benzodioxin-5-yl)methyl]-4-(pyridin-4-yl)benzamide, SULFATE ION
著者Judge, R.A., Hobson, A.D.
登録日2018-08-01
公開日2018-11-14
最終更新日2019-01-16
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure Based Drug Design.
J. Med. Chem., 61, 2018
6ED6
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CRYSTAL STRUCTURE OF ROCK2 WITH A PYRIDINYLBENZAMIDE BASED INHIBITOR
分子名称:Rho-associated protein kinase 2, N-[(2,3-dihydro-1,4-benzodioxin-5-yl)methyl]-4-(pyridin-4-yl)benzamide
著者Judge, R.A., Hobson, A.D.
登録日2018-08-08
公開日2018-11-14
最終更新日2019-01-16
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure Based Drug Design.
J. Med. Chem., 61, 2018