Author results

2Q3F
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X-RAY CRYSTAL STRUCTURE OF PUTATIVE HUMAN RAS-RELATED GTP BINDING D IN COMPLEX WITH GMPPNP
分子名称:Ras-related GTP-binding protein D, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
著者Mulichak, A.M., Rabeh, W.M., Tempel, W., Nedyalkova, L., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Keefe, L.J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2007-05-30
公開日2007-06-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of human Ras-related GTP-binding D.
To be published
3MSE
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CRYSTAL STRUCTURE OF C-TERMINAL DOMAIN OF PF110239.
分子名称:Calcium-dependent protein kinase, putative, CALCIUM ION, ...
著者Wernimont, A.K., Artz, J.D., Hutchinson, A., Sullivan, H., Weadge, J., Tempel, W., Bochkarev, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R., Lin, Y.H., Neculai, A.M., Amani, M., Structural Genomics Consortium (SGC)
登録日2010-04-29
公開日2010-06-23
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of C-terminal domain of PF110239
To be Published
3OZ6
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CRYSTAL STRUCTURE OF MAPK FROM CRYPTOSPORIDIUM PARVUM, CGD2_1960
分子名称:Mitogen-activated protein kinase 1, serine/threonine protein kinase, GLYCEROL
著者Wernimont, A.K., Lew, J., Lin, Y.H., Sullivan, H., Hassanali, A., Kozieradzki, I., Cossar, D., Arrowsmith, C.H., Bochkarev, A., Bountra, C., Edwards, A.M., Weigelt, J., Hui, R., Neculai, A.M., Hutchinson, A., Structural Genomics Consortium (SGC)
登録日2010-09-24
公開日2010-12-08
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Crystal structure of MapK from Cryptosporidium Parvum, cgd2_1960
To be Published
3P1W
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CRYSTAL STRUCTURE OF RAB GDI FROM PLASMODIUM FALCIPARUM, PFL2060C
分子名称:RabGDI protein
著者Wernimont, A.K., Neculai, A.M., Weadge, J., MacKenzie, F., Cossar, D., Tempel, W., Bochkarev, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Langsley, G., Bosch, J., Hui, R., Pizzaro, J.C., Hutchinson, A., Structural Genomics Consortium (SGC)
登録日2010-09-30
公開日2010-12-15
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structure of RAB GDI from Plasmodium Falciparum, PFL2060c
To be published
3Q5I
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CRYSTAL STRUCTURE OF PBANKA_031420
分子名称:Protein kinase, CALCIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Wernimont, A.K., Hutchinson, A., Sullivan, H., Panico, E., Crombet, L., Cossar, D., Hassani, A., Vedadi, M., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R., Neculai, A.M., Amani, M., Structural Genomics Consortium (SGC)
登録日2010-12-28
公開日2011-06-01
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of CDPK1 from Plasmodium Bergheii, PBANKA_031420
To be Published
5DYK
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CRYSTAL STRUCTURE OF PF3D7_1436600
分子名称:CGMP-dependent protein kinase, 1,2-ETHANEDIOL, SULFATE ION, ...
著者Wernimont, A.K., Tempel, W., He, H., Seitova, A., Hills, T., Neculai, A.M., Baker, D.A., Flueck, C., Kettleborough, C.A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Hui, R., Hutchinson, A., El Bakkouri, M., Structural Genomics Consortium (SGC)
登録日2015-09-24
公開日2015-11-04
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal Structure of PF3D7_1436600
To Be Published
5DYL
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CRYSTAL STRUCTURE OF PVX_084705
分子名称:cGMP-dependent protein kinase, putative
著者Wernimont, A.K., Tempel, W., He, H., Seitova, A., Hills, T., Neculai, A.M., Baker, D.A., Flueck, C., Kettleborough, C.A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Hui, R., Hutchinson, A., El Bakkouri, M., Structural Genomics Consortium (SGC)
登録日2015-09-24
公開日2015-11-04
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of PVX_084705
To Be Published
5FET
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CRYSTAL STRUCTURE OF PVX_084705 IN PRESENCE OF COMPOUND 2
分子名称:cGMP-dependent protein kinase, putative, 4-[7-[(dimethylamino)methyl]-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-amine
著者Wernimont, A.K., Tempel, W., Walker, J.R., He, H., Seitova, A., Hills, T., Neculai, A.M., Baker, D.A., Flueck, C., Kettleborough, C.A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Hui, R., Hutchinson, A., El Bakkouri, M., Structural Genomics Consortium (SGC)
登録日2015-12-17
公開日2016-01-13
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (3.07 Å)
主引用文献Crystal Structure of PVX_084705 in presence of Compound 2
To be published
5OCH
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THE CRYSTAL STRUCTURE OF HUMAN ABCB8 IN AN OUTWARD-FACING STATE
分子名称:ATP-binding cassette sub-family B member 8, mitochondrial, ADENOSINE-5'-DIPHOSPHATE, ...
著者Faust, B., Pike, A.C.W., Shintre, C.A., Quiqley, A.M., Chu, A., Barr, A., Shrestha, L., Mukhopadhyay, S., Borkowska, O., Chalk, R., Burgess-Brown, N.A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC)
登録日2017-06-30
公開日2018-07-25
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献The crystal structure of human ABCB8 in an outward-facing state
To Be Published
1HV2
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SOLUTION STRUCTURE OF YEAST ELONGIN C IN COMPLEX WITH A VON HIPPEL-LINDAU PEPTIDE
分子名称:ELONGIN C, VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR
著者Botuyan, M.V., Mer, G., Yi, G.-S., Koth, C.M., Case, D.A., Edwards, A.M., Chazin, W.J., Arrowsmith, C.H.
登録日2001-01-05
公開日2001-09-06
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure and dynamics of yeast elongin C in complex with a von Hippel-Lindau peptide.
J.Mol.Biol., 312, 2001
1QUQ
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COMPLEX OF REPLICATION PROTEIN A SUBUNITS RPA14 AND RPA32
分子名称:PROTEIN (REPLICATION PROTEIN A 32 KD SUBUNIT), PROTEIN (REPLICATION PROTEIN A 14 KD SUBUNIT)
著者Bochkarev, A., Bochkareva, E., Frappier, L., Edwards, A.M.
登録日1999-07-02
公開日1999-08-13
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of the complex of replication protein A subunits RPA32 and RPA14 reveals a mechanism for single-stranded DNA binding.
EMBO J., 18, 1999
6CNH
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HUMAN PRPF4B IN COMPLEX WITH REBASTINIB
分子名称:Serine/threonine-protein kinase PRP4 homolog, 4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide, SULFATE ION
著者Godoi, P.H.C., Santiago, A.S., Ramos, P.Z., Fala, A.M., Salmazo, A.P.T., Counago, R.M., Righetto, G.L., Silva, P.N.B., Gileadi, O., Guimaraes, C.R.W., Massirer, K.B., Arruda, P., Elkins, J.M., Edwards, A.M., Structural Genomics Consortium (SGC)
登録日2018-03-08
公開日2018-03-28
最終更新日2019-04-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the human PRPF4B in complex with Rebastinib
To be Published
1DPU
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SOLUTION STRUCTURE OF THE C-TERMINAL DOMAIN OF HUMAN RPA32 COMPLEXED WITH UNG2(73-88)
分子名称:REPLICATION PROTEIN A (RPA32) C-TERMINAL DOMAIN, URACIL DNA GLYCOSYLASE (UNG2)
著者Mer, G., Edwards, A.M., Chazin, W.J.
登録日1999-12-27
公開日2000-11-10
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural basis for the recognition of DNA repair proteins UNG2, XPA, and RAD52 by replication factor RPA.
Cell(Cambridge,Mass.), 103, 2000
1EF4
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SOLUTION STRUCTURE OF THE ESSENTIAL RNA POLYMERASE SUBUNIT RPB10 FROM METHANOBACTERIUM THERMOAUTOTROPHICUM
分子名称:DNA-DIRECTED RNA POLYMERASE, ZINC ION
著者Mackereth, C.D., Arrowsmith, C.H., Edwards, A.M., Mcintosh, L.P., Northeast Structural Genomics Consortium (NESG)
登録日2000-02-07
公開日2000-06-14
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Zinc-bundle structure of the essential RNA polymerase subunit RPB10 from Methanobacterium thermoautotrophicum.
Proc.Natl.Acad.Sci.USA, 97, 2000
1EIJ
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NMR ENSEMBLE OF METHANOBACTERIUM THERMOAUTOTROPHICUM PROTEIN 1615
分子名称:HYPOTHETICAL PROTEIN MTH1615
著者Christendat, D., Booth, V., Gernstein, M., Arrowsmith, C.H., Edwards, A.M., Northeast Structural Genomics Consortium (NESG)
登録日2000-02-25
公開日2000-11-03
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural proteomics of an archaeon.
Nat.Struct.Biol., 7, 2000
1EIK
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SOLUTION STRUCTURE OF RNA POLYMERASE SUBUNIT RPB5 FROM METHANOBACTERIUM THERMOAUTOTROPHICUM
分子名称:RNA POLYMERASE SUBUNIT RPB5
著者Yee, A., Booth, V., Dharamsi, A., Engel, A., Edwards, A.M., Arrowsmith, C.H., Northeast Structural Genomics Consortium (NESG)
登録日2000-02-25
公開日2000-06-21
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of the RNA polymerase subunit RPB5 from Methanobacterium thermoautotrophicum.
Proc.Natl.Acad.Sci.USA, 97, 2000
1EJ2
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CRYSTAL STRUCTURE OF METHANOBACTERIUM THERMOAUTOTROPHICUM NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE WITH BOUND NAD+
分子名称:NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE, SULFATE ION, SODIUM ION, ...
著者Saridakis, V., Christendat, D., Kimber, M.S., Edwards, A.M., Pai, E.F., Midwest Center for Structural Genomics (MCSG), Northeast Structural Genomics Consortium (NESG)
登録日2000-02-29
公開日2001-03-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Insights into ligand binding and catalysis of a central step in NAD+ synthesis: structures of Methanobacterium thermoautotrophicum NMN adenylyltransferase complexes.
J.Biol.Chem., 276, 2001
1EJE
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CRYSTAL STRUCTURE OF AN FMN-BINDING PROTEIN
分子名称:FMN-BINDING PROTEIN, NICKEL (II) ION, SULFATE ION, ...
著者Christendat, D., Saridakis, V., Bochkarev, A., Arrowsmith, C., Edwards, A.M., Northeast Structural Genomics Consortium (NESG)
登録日2000-03-02
公開日2000-10-11
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural proteomics of an archaeon.
Nat.Struct.Biol., 7, 2000
1ENW
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ELONGATION FACTOR TFIIS DOMAIN II
分子名称:TRANSCRIPTION ELONGATION FACTOR S-II
著者Morin, P.E., Awrey, D.E., Edwards, A.M., Arrowsmith, C.H.
登録日2000-03-21
公開日2000-04-12
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Elongation factor TFIIS contains three structural domains: solution structure of domain II.
Proc.Natl.Acad.Sci.USA, 93, 1996
1EO0
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CONSERVED DOMAIN COMMON TO TRANSCRIPTION FACTORS TFIIS, ELONGIN A, CRSP70
分子名称:TRANSCRIPTION ELONGATION FACTOR S-II
著者Booth, V., Koth, C., Edwards, A.M., Arrowsmith, C.H., Northeast Structural Genomics Consortium (NESG)
登録日2000-03-21
公開日2000-05-03
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure of a conserved domain common to the transcription factors TFIIS, elongin A, and CRSP70
J.Biol.Chem., 275, 2000
1EP0
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HIGH RESOLUTION CRYSTAL STRUCTURE OF DTDP-6-DEOXY-D-XYLO-4-HEXULOSE 3,5-EPIMERASE FROM METHANOBACTERIUM THERMOAUTOTROPHICUM
分子名称:DTDP-6-DEOXY-D-XYLO-4-HEXULOSE 3,5-EPIMERASE
著者Christendat, D., Saridakis, V., Bochkarev, A., Pai, E.F., Arrowsmith, C.H., Edwards, A.M., Northeast Structural Genomics Consortium (NESG)
登録日2000-03-24
公開日2000-12-13
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of dTDP-4-keto-6-deoxy-D-hexulose 3,5-epimerase from Methanobacterium thermoautotrophicum complexed with dTDP.
J.Biol.Chem., 275, 2000
1EPZ
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CRYSTAL STRUCTURE OF DTDP-6-DEOXY-D-XYLO-4-HEXULOASE 3,5-EPIMERASE FROM METHANOBACTERIUM THERMOAUTOTROPHICUM WITH BOUND LIGAND.
分子名称:DTDP-6-DEOXY-D-XYLO-4-HEXULOSE 3,5-EPIMERASE, THYMIDINE-5'-DIPHOSPHATE
著者Christendat, D., Saridakis, V., Bochkarev, A., Pai, E.F., Arrowsmith, C., Edwards, A.M.
登録日2000-03-30
公開日2000-12-13
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure of dTDP-4-keto-6-deoxy-D-hexulose 3,5-epimerase from Methanobacterium thermoautotrophicum complexed with dTDP.
J.Biol.Chem., 275, 2000
1HYB
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CRYSTAL STRUCTURE OF AN ACTIVE SITE MUTANT OF METHANOBACTERIUM THERMOAUTOTROPHICUM NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE
分子名称:NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE, SULFATE ION, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE
著者Saridakis, V., Christendat, D., Kimber, M.S., Edwards, A.M., Pai, E.F.
登録日2001-01-18
公開日2001-03-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insights into ligand binding and catalysis of a central step in NAD+ synthesis: structures of Methanobacterium thermoautotrophicum NMN adenylyltransferase complexes.
J.Biol.Chem., 276, 2001
1IIO
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NMR-BASED STRUCTURE OF THE CONSERVED PROTEIN MTH865 FROM THE ARCHEA METHANOBACTERIUM THERMOAUTOTROPHICUM
分子名称:conserved hypothetical protein MTH865
著者Lee, G.M., Edwards, A.M., Arrowsmith, C.H., McIntosh, L.P.
登録日2001-04-23
公開日2001-10-17
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献NMR-based structure of the conserved protein MTH865 from the archaeon Methanobacterium thermoautotrophicum.
J.Biomol.NMR, 21, 2001
1JW2
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SOLUTION STRUCTURE OF HEMOLYSIN EXPRESSION MODULATING PROTEIN HHA FROM ESCHERICHIA COLI. ONTARIO CENTRE FOR STRUCTURAL PROTEOMICS TARGET EC0308_1_72; NORTHEAST STRUCTURAL GENOMICS TARGET ET88
分子名称:HEMOLYSIN EXPRESSION MODULATING PROTEIN Hha
著者Chang, X., Yee, A., Savchenko, A., Edwards, A.M., Arrowsmith, C.H., Northeast Structural Genomics Consortium (NESG)
登録日2001-09-02
公開日2002-02-27
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献An NMR approach to structural proteomics
Proc.Natl.Acad.Sci.USA, 99, 2002