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1KHD
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BU of 1khd by Molmil
Crystal Structure Analysis of the anthranilate phosphoribosyltransferase from Erwinia carotovora at 1.9 resolution (current name, Pectobacterium carotovorum)
Descriptor: Anthranilate phosphoribosyltransferase
Authors:Kim, C, Xuong, N.-H, Edwards, S, Madhusudan, Yee, M.-C, Spraggon, G, Mills, S.E.
Deposit date:2001-11-29
Release date:2002-10-23
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:The Crystal Structure of Anthranilate Phosphoribosyltransferase from the Enterobacterium Pectobacterium carotovorum
FEBS Lett., 523, 2002
1KGZ
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BU of 1kgz by Molmil
Crystal Structure Analysis of the Anthranilate Phosphoribosyltransferase from Erwinia carotovora (current name, Pectobacterium carotovorum)
Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, MANGANESE (II) ION, ...
Authors:Kim, C, Xuong, N.-H, Edwards, S, Madhusudan, Yee, M.-C, Spraggon, G, Mills, S.E.
Deposit date:2001-11-28
Release date:2002-10-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Crystal Structure of Anthranilate Phosphoribosyltransferase from the Enterobacterium Pectobacterium carotovorum
FEBS Lett., 523, 2002
2L8B
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BU of 2l8b by Molmil
TraI (381-569)
Descriptor: Protein traI
Authors:Wright, N.T, Raththagala, M.U, Edwards, S, Krueger, S, Schildbach, J.F.
Deposit date:2011-01-07
Release date:2012-01-11
Last modified:2023-02-08
Method:SOLUTION NMR
Cite:Solution structure and small angle scattering analysis of TraI (381-569).
Proteins, 80, 2012
8TJF
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BU of 8tjf by Molmil
monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the CH1-CL interface
Descriptor: Fab Lambda light chain, IgG1 Fab heavy chain
Authors:Oganesyan, V.Y, van Dyk, N, Mazor, Y, Chiang, C.
Deposit date:2023-07-21
Release date:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Robust production of monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the C H 1-C lambda interface.
Mabs, 15, 2023
8TI4
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BU of 8ti4 by Molmil
monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the CH1-CL interface
Descriptor: GLYCEROL, IgG1 Fab heavy chain, mutated to promote correct pairing, ...
Authors:Oganesyan, V.Y, van Dyk, N, Mazor, Y.
Deposit date:2023-07-19
Release date:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Robust production of monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the C H 1-C lambda interface.
Mabs, 15, 2023
7QPN
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BU of 7qpn by Molmil
Crystal Structure of Phosphatidylinositol 5-Phosphate 4-Kinase (PI5P4K2C) bound to an allosteric inhibitor and AMP-PNP
Descriptor: 5-methyl-2-(2-propan-2-ylphenyl)-~{N}-(pyridin-2-ylmethyl)pyrrolo[3,2-d]pyrimidin-4-amine, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Phosphatidylinositol 5-Phosphate 4-Kinase (PI5P4K2C)
Authors:Howard, T.D, Ogg, D.T.
Deposit date:2022-01-05
Release date:2022-05-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Development of Selective Phosphatidylinositol 5-Phosphate 4-Kinase gamma Inhibitors with a Non-ATP-competitive, Allosteric Binding Mode.
J.Med.Chem., 65, 2022
7QIE
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BU of 7qie by Molmil
Crystal Structure of Phosphatidylinositol 5-Phosphate 4-Kinase (PI5P4K2C) bound to an allosteric inhibitor
Descriptor: 5-methyl-2-(2-propan-2-ylphenyl)-~{N}-(pyridin-2-ylmethyl)pyrrolo[3,2-d]pyrimidin-4-amine, Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma
Authors:Howard, T.D, Ogg, D.T.
Deposit date:2021-12-14
Release date:2022-05-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Development of Selective Phosphatidylinositol 5-Phosphate 4-Kinase gamma Inhibitors with a Non-ATP-competitive, Allosteric Binding Mode.
J.Med.Chem., 65, 2022
8BQ4
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BU of 8bq4 by Molmil
Crystal Structure of Phosphatidylinositol 5-Phosphate 4-Kinase (PI5P4K2C) bound to an inhibitor
Descriptor: 6-methyl-~{N}-(4-methylsulfonylphenyl)thieno[2,3-d]pyrimidin-4-amine, Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma
Authors:Ogg, D.J, Howard, T.D.
Deposit date:2022-11-18
Release date:2022-12-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:The Identification of Potent, Selective, and Brain Penetrant PI5P4K gamma Inhibitors as In Vivo-Ready Tool Molecules.
J.Med.Chem., 66, 2023
8C8C
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BU of 8c8c by Molmil
Crystal Structure of Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (PI5P4Ka) bound to an inhibitor
Descriptor: Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, ~{N}-(3-chloranyl-4-methoxy-phenyl)-7-(3,4-dimethylphenyl)pyrrolo[2,3-d]pyrimidin-4-amine
Authors:Harborne, S.P.D, Howard, T.D, Ogg, D.T.
Deposit date:2023-01-19
Release date:2023-04-26
Last modified:2023-06-07
Method:X-RAY DIFFRACTION (2.096 Å)
Cite:Identification of ARUK2002821 as an isoform-selective PI5P4K alpha inhibitor.
Rsc Med Chem, 14, 2023

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