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1YAJ
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BU of 1yaj by Molmil
Crystal Structure of Human Liver Carboxylesterase in complex with benzil
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, BENZOIC ACID, CES1 protein, ...
Authors:Fleming, C.D, Bencharit, S, Edwards, C.C, Hyatt, J.L, Morton, C.M, Howard-Williams, E.L, Potter, P.M, Redinbo, M.R.
Deposit date:2004-12-17
Release date:2005-08-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil.
J.Mol.Biol., 352, 2005
1YA4
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BU of 1ya4 by Molmil
Crystal Structure of Human Liver Carboxylesterase 1 in complex with tamoxifen
Descriptor: (Z)-2-[4-(1,2)-DIPHENYL-1-BUTENYL)-PHENOXY]-N,N-DIMETHYLETHANAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CES1 protein, ...
Authors:Fleming, C.D, Bencharit, S, Edwards, C.C, Hyatt, J.L, Morton, C.L, Howard-Williams, E.L, Potter, P.M, Redinbo, M.R.
Deposit date:2004-12-17
Release date:2005-08-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil.
J.Mol.Biol., 352, 2005
1YAH
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BU of 1yah by Molmil
Crystal Structure of Human Liver Carboxylesterase complexed to Etyl Acetate; A Fatty Acid Ethyl Ester Analogue
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CES1 protein, ETHYL ACETATE, ...
Authors:Fleming, C.D, Bencahrit, S, Edwards, C.C, Hyatt, J.L, Morton, C.L, Howard-Williams, E.L, Potter, P.M, Redinbo, M.R.
Deposit date:2004-12-17
Release date:2005-08-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil.
J.Mol.Biol., 352, 2005
1YA8
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BU of 1ya8 by Molmil
Crystal Structure of Human Liver Carboxylesterase in complex with cleavage products of Mevastatin
Descriptor: (1S,7S,8S,8AR)-1,2,3,7,8,8A-HEXAHYDRO-7-METHYL-8-[2-[(2R,4R)-TETRAHYDRO-4-HY DROXY-6-OXO-2H-PYRAN-2-YL]ETHYL]-1-NAPHTHALENOL, 2-METHYLBUTANOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Fleming, C.D, Bencharit, S, Edwards, C.C, Hyatt, J.L, Morton, C.L, Howard-Williams, E.L, Potter, P.M, Redinbo, M.R.
Deposit date:2004-12-17
Release date:2005-08-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil.
J.Mol.Biol., 352, 2005
2DQY
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BU of 2dqy by Molmil
Crystal structure of human carboxylesterase in complex with cholate and palmitate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLIC ACID, Liver carboxylesterase 1, ...
Authors:Bencharit, S, Edwards, C.C, Morton, C.L, Howard-Williams, E.L, Potter, P.M, Redinbo, M.R.
Deposit date:2006-06-02
Release date:2006-08-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1
J.Mol.Biol., 363, 2006
2H7C
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BU of 2h7c by Molmil
Crystal structure of human carboxylesterase in complex with Coenzyme A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COENZYME A, ...
Authors:Bencharit, S, Edwards, C.C, Morton, C.L, Howard-Williams, E.L, Potter, P.M, Redinbo, M.R.
Deposit date:2006-06-02
Release date:2006-08-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1
J.Mol.Biol., 363, 2006
2DQZ
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BU of 2dqz by Molmil
Crystal structure of human carboxylesterase in complex with homatropine, coenzyme A, and palmitate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, COENZYME A, FLUORIDE ION, ...
Authors:Bencharit, S, Redinbo, M.R.
Deposit date:2006-06-02
Release date:2006-08-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1
J.Mol.Biol., 363, 2006
2DR0
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BU of 2dr0 by Molmil
Crystal structure of human carboxylesterase in complex with taurocholate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Liver carboxylesterase 1, N-acetyl-alpha-neuraminic acid, ...
Authors:Bencharit, S, Redinbo, M.R.
Deposit date:2006-06-02
Release date:2006-08-29
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1
J.Mol.Biol., 363, 2006
2HRR
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BU of 2hrr by Molmil
Crystal structure of Human Liver Carboxylesterase 1 (hCE1) in covalent complex with the nerve agent Tabun (GA)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Liver carboxylesterase 1, N-acetyl-alpha-neuraminic acid, ...
Authors:Fleming, C.D, Redinbo, M.R.
Deposit date:2006-07-20
Release date:2007-05-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structures of Human Carboxylesterase 1 in Covalent Complexes with the Chemical Warfare Agents Soman and Tabun.
Biochemistry, 46, 2007
2HRQ
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BU of 2hrq by Molmil
Crystal structure of Human Liver Carboxylesterase 1 (hCE1) in covalent complex with the nerve agent Soman (GD)
Descriptor: (1R)-1,2,2-TRIMETHYLPROPYL (R)-METHYLPHOSPHINATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Liver carboxylesterase 1, ...
Authors:Fleming, C.D, Redinbo, M.R.
Deposit date:2006-07-20
Release date:2007-05-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structures of Human Carboxylesterase 1 in Covalent Complexes with the Chemical Warfare Agents Soman and Tabun.
Biochemistry, 46, 2007
3K9B
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BU of 3k9b by Molmil
Crystal structure of human liver carboxylesterase 1 (hCE1) in covalent complex with the nerve agent Cyclosarin (GF)
Descriptor: Liver carboxylesterase 1, cyclohexyl (S)-methylphosphonofluoridoate
Authors:Hemmert, A.C, Redinbo, M.R.
Deposit date:2009-10-15
Release date:2010-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Human carboxylesterase 1 stereoselectively binds the nerve agent cyclosarin and spontaneously hydrolyzes the nerve agent sarin.
Mol.Pharmacol., 77, 2010

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