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1YA4
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CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE 1 IN COMPLEX WITH TAMOXIFEN
Descriptor:CES1 protein, N-ACETYL-D-GLUCOSAMINE, O-SIALIC ACID, ...
Authors:Fleming, C.D., Bencharit, S., Edwards, C.C., Hyatt, J.L., Morton, C.L., Howard-Williams, E.L., Potter, P.M., Redinbo, M.R.
Deposit date:2004-12-17
Release date:2005-08-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil.
J.Mol.Biol., 352, 2005
1YA8
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CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEX WITH CLEAVAGE PRODUCTS OF MEVASTATIN
Descriptor:CES1 protein, N-ACETYL-D-GLUCOSAMINE, O-SIALIC ACID, ...
Authors:Fleming, C.D., Bencharit, S., Edwards, C.C., Hyatt, J.L., Morton, C.L., Howard-Williams, E.L., Potter, P.M., Redinbo, M.R.
Deposit date:2004-12-17
Release date:2005-08-02
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil.
J.Mol.Biol., 352, 2005
1YAH
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CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE COMPLEXED TO ETYL ACETATE; A FATTY ACID ETHYL ESTER ANALOGUE
Descriptor:CES1 protein, N-ACETYL-D-GLUCOSAMINE, O-SIALIC ACID, ...
Authors:Fleming, C.D., Bencahrit, S., Edwards, C.C., Hyatt, J.L., Morton, C.L., Howard-Williams, E.L., Potter, P.M., Redinbo, M.R.
Deposit date:2004-12-17
Release date:2005-08-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil.
J.Mol.Biol., 352, 2005
1YAJ
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CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEX WITH BENZIL
Descriptor:CES1 protein, N-ACETYL-D-GLUCOSAMINE, O-SIALIC ACID, ...
Authors:Fleming, C.D., Bencharit, S., Edwards, C.C., Hyatt, J.L., Morton, C.M., Howard-Williams, E.L., Potter, P.M., Redinbo, M.R.
Deposit date:2004-12-17
Release date:2005-08-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil.
J.Mol.Biol., 352, 2005
2DQY
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CRYSTAL STRUCTURE OF HUMAN CARBOXYLESTERASE IN COMPLEX WITH CHOLATE AND PALMITATE
Descriptor:Liver carboxylesterase 1, N-ACETYL-D-GLUCOSAMINE, O-SIALIC ACID, ...
Authors:Bencharit, S., Edwards, C.C., Morton, C.L., Howard-Williams, E.L., Potter, P.M., Redinbo, M.R.
Deposit date:2006-06-02
Release date:2006-08-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1
J.Mol.Biol., 363, 2006
2H7C
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CRYSTAL STRUCTURE OF HUMAN CARBOXYLESTERASE IN COMPLEX WITH COENZYME A
Descriptor:Liver carboxylesterase 1, N-ACETYL-D-GLUCOSAMINE, SULFATE ION, ...
Authors:Bencharit, S., Edwards, C.C., Morton, C.L., Howard-Williams, E.L., Potter, P.M., Redinbo, M.R.
Deposit date:2006-06-02
Release date:2006-08-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1
J.Mol.Biol., 363, 2006
2DQZ
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CRYSTAL STRUCTURE OF HUMAN CARBOXYLESTERASE IN COMPLEX WITH HOMATROPINE, COENZYME A, AND PALMITATE
Descriptor:Liver carboxylesterase 1, N-ACETYL-D-GLUCOSAMINE, O-SIALIC ACID, ...
Authors:Bencharit, S., Redinbo, M.R.
Deposit date:2006-06-02
Release date:2006-08-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1
J.Mol.Biol., 363, 2006
2DR0
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CRYSTAL STRUCTURE OF HUMAN CARBOXYLESTERASE IN COMPLEX WITH TAUROCHOLATE
Descriptor:Liver carboxylesterase 1, N-ACETYL-D-GLUCOSAMINE, O-SIALIC ACID, ...
Authors:Bencharit, S., Redinbo, M.R.
Deposit date:2006-06-02
Release date:2006-08-29
Last modified:2011-10-12
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1
J.Mol.Biol., 363, 2006
2HRQ
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CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE 1 (HCE1) IN COVALENT COMPLEX WITH THE NERVE AGENT SOMAN (GD)
Descriptor:Liver carboxylesterase 1, N-ACETYL-D-GLUCOSAMINE, O-SIALIC ACID, ...
Authors:Fleming, C.D., Redinbo, M.R.
Deposit date:2006-07-20
Release date:2007-05-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structures of Human Carboxylesterase 1 in Covalent Complexes with the Chemical Warfare Agents Soman and Tabun.
Biochemistry, 46, 2007
2HRR
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CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE 1 (HCE1) IN COVALENT COMPLEX WITH THE NERVE AGENT TABUN (GA)
Descriptor:Liver carboxylesterase 1, N-ACETYL-D-GLUCOSAMINE, O-SIALIC ACID, ...
Authors:Fleming, C.D., Redinbo, M.R.
Deposit date:2006-07-20
Release date:2007-05-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structures of Human Carboxylesterase 1 in Covalent Complexes with the Chemical Warfare Agents Soman and Tabun.
Biochemistry, 46, 2007
3K9B
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CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE 1 (HCE1) IN COVALENT COMPLEX WITH THE NERVE AGENT CYCLOSARIN (GF)
Descriptor:Liver carboxylesterase 1, cyclohexyl (S)-methylphosphonofluoridoate
Authors:Hemmert, A.C., Redinbo, M.R.
Deposit date:2009-10-15
Release date:2010-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Human carboxylesterase 1 stereoselectively binds the nerve agent cyclosarin and spontaneously hydrolyzes the nerve agent sarin.
Mol.Pharmacol., 77, 2010