2Y6S
| Structure of an Ebolavirus-protective antibody in complex with its mucin-domain linear epitope | Descriptor: | ENVELOPE GLYCOPROTEIN, HEAVY CHAIN, LIGHT CHAIN | Authors: | Olal, D.O, Kuehne, A, Lee, J.E, Bale, S, Dye, J.M, Saphire, E.O. | Deposit date: | 2011-01-25 | Release date: | 2012-01-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of an Ebola Virus-Protective Antibody in Complex with its Mucin-Domain Linear Epitope. J.Virol., 86, 2012
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4R0R
| Ebolavirus GP Prehairpin Intermediate Mimic | Descriptor: | eboIZN21 | Authors: | Clinton, T.R, Weinstock, M.T, Jacobsen, M.T, Szabo-Fresnais, N, Pandya, M.J, Whitby, F.G, Herbert, A.S, Prugar, L.I, McKinnon, R, Hill, C.P, Welch, B.D, Dye, J.M, Eckert, D.M, Kay, M.S. | Deposit date: | 2014-08-01 | Release date: | 2014-10-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Design and characterization of ebolavirus GP prehairpin intermediate mimics as drug targets. Protein Sci., 24, 2015
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5L4Q
| Crystal Structure of Adaptor Protein 2 Associated Kinase 1 (AAK1) in Complex with LKB1 (AAK1 Dual Inhibitor) | Descriptor: | 1,2-ETHANEDIOL, AP2-associated protein kinase 1, ~{N}-[5-(4-cyanophenyl)-1~{H}-pyrrolo[2,3-b]pyridin-3-yl]pyridine-3-carboxamide | Authors: | Sorrell, F.J, Williams, E, Fox, N, Abdul Azeez, K.R, Gileadi, O, von Delft, F, Edwards, A.M, Bountra, C, Elkins, J.M, Knapp, S. | Deposit date: | 2016-05-26 | Release date: | 2016-06-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Synthesis and Structure-Activity Relationships of 3,5-Disubstituted-pyrrolo[2,3- b]pyridines as Inhibitors of Adaptor-Associated Kinase 1 with Antiviral Activity. J.Med.Chem., 2019
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8TMA
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8TM1
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3VE0
| Crystal structure of Sudan Ebolavirus Glycoprotein (strain Boniface) bound to 16F6 | Descriptor: | 16F6 Antibody chain A, 16F6 Antibody chain B, Envelope glycoprotein, ... | Authors: | Saphire, E.O, Bale, S, Dias, J.M. | Deposit date: | 2012-01-06 | Release date: | 2012-04-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.353 Å) | Cite: | Structural basis for differential neutralization of ebolaviruses. Viruses, 4, 2012
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7QQB
| Crystal structure of the envelope glycoprotein complex of Puumala virus in complex with the scFv fragment of the broadly neutralizing human antibody ADI-42898 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein, GLYCEROL, ... | Authors: | Serris, A, Rey, F.A, Guardado-Calvo, P. | Deposit date: | 2022-01-07 | Release date: | 2023-06-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural and mechanistic basis of neutralization by a pan-hantavirus protective antibody. Sci Transl Med, 15, 2023
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6VKF
| CCHFV GP38 (IbAr10200) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GP38 | Authors: | Mishra, A.K, McLellan, J.S. | Deposit date: | 2020-01-20 | Release date: | 2020-02-05 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.524 Å) | Cite: | Structure and Characterization of Crimean-Congo Hemorrhagic Fever Virus GP38. J.Virol., 94, 2020
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3S88
| Crystal structure of Sudan Ebolavirus Glycoprotein (strain Gulu) bound to 16F6 | Descriptor: | 16F6 - Heavy chain, 16F6 - Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Saphire, E.O, Dias, J.M, Bale, S. | Deposit date: | 2011-05-27 | Release date: | 2011-12-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.351 Å) | Cite: | A shared structural solution for neutralizing ebolaviruses. Nat.Struct.Mol.Biol., 18, 2011
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6MAM
| Cleaved Ebola GP in complex with a broadly neutralizing human antibody, ADI-15946 | Descriptor: | ADI-15946 Fab Heavy Chain, ADI-15946 Fab Light Chain, Envelope glycoprotein, ... | Authors: | West, B.R, Moyer, C.L, Fusco, M.L, Saphire, E.O. | Deposit date: | 2018-08-28 | Release date: | 2019-03-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (4.1 Å) | Cite: | Structural basis of broad ebolavirus neutralization by a human survivor antibody. Nat. Struct. Mol. Biol., 26, 2019
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7M8J
| SARS-CoV-2 S-NTD + Fab CM25 | Descriptor: | CM25 Fab - Heavy Chain, CM25 Fab - Light Chain, Spike protein S1 | Authors: | Johnson, N.V, Mclellan, J.S. | Deposit date: | 2021-03-29 | Release date: | 2021-05-19 | Last modified: | 2021-06-16 | Method: | ELECTRON MICROSCOPY (3.48 Å) | Cite: | Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes. Science, 372, 2021
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