Author results

1ITG
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HIV-1 INTEGRASE: SIMILARITY TO OTHER POLYNUCLEOTIDYL TRANSFERASES
Descriptor:HIV-1 INTEGRASE, CACODYLATE ION
Authors:Dyda, F., Hickman, A.B., Jenkins, T.M., Engelman, A., Craigie, R., Davies, D.R.
Deposit date:1994-11-21
Release date:1995-05-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases.
Science, 266, 1994
1PYD
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CATALYTIC CENTERS IN THE THIAMIN DIPHOSPHATE DEPENDENT ENZYME PYRUVATE DECARBOXYLASE AT 2.4 ANGSTROMS RESOLUTION
Descriptor:PYRUVATE DECARBOXYLASE, MAGNESIUM ION, THIAMIN DIPHOSPHATE
Authors:Furey, W., Dyda, F.
Deposit date:1993-03-23
Release date:1994-04-30
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Catalytic centers in the thiamin diphosphate dependent enzyme pyruvate decarboxylase at 2.4-A resolution.
Biochemistry, 32, 1993
1UUT
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THE NUCLEASE DOMAIN OF ADENO-ASSOCIATED VIRUS REP COMPLEXED WITH THE RBE' STEMLOOP OF THE VIRAL INVERTED TERMINAL REPEAT
Descriptor:REP PROTEIN, 5'-D(*CP*AP*GP*CP*TP*CP*TP*TP*TP*GP *AP*GP*CP*TP*G)-3', MAGNESIUM ION, ...
Authors:Dyda, F., Hickman, A.B., Ronning, D.R., Perez, Z.N., Kotin, R.M.
Deposit date:2004-01-10
Release date:2004-02-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Nuclease Domain of Adeno-Associated Virus Rep Coordinates Replication Initiation Using Two Distinct DNA Recognition Interfaces
Mol.Cell, 13, 2004
6B67
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HUMAN PP2CALPHA (PPM1A) COMPLEXED WITH CYCLIC PEPTIDE C(MPSIPYVA)
Descriptor:Protein phosphatase 1A, cyclic peptide c(MpSIpYVA), CALCIUM ION
Authors:Dyda, F., Kosek, D.
Deposit date:2017-10-01
Release date:2018-04-11
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A trapped human PPM1A-phosphopeptide complex reveals structural features critical for regulation of PPM protein phosphatase activity.
J. Biol. Chem., 293, 2018
6DWW
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HERMES TRANSPOSASE DELETION DIMER COMPLEX WITH (A/T) DNA AND MN2+
Descriptor:Hermes transposase, DNA (5'-D(*AP*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), DNA (25-MER), ...
Authors:Dyda, F., Voth, A.R., Hickman, A.B.
Deposit date:2018-06-28
Release date:2018-09-19
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (2.851 Å)
Cite:Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase.
Nucleic Acids Res., 46, 2018
6DWY
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HERMES TRANSPOSASE DELETION DIMER COMPLEX WITH (C/G) DNA AND CA2+
Descriptor:Hermes transposase, DNA (5'-D(*AP*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), DNA (26-MER), ...
Authors:Dyda, F., Hickman, A.B.
Deposit date:2018-06-28
Release date:2018-09-19
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase.
Nucleic Acids Res., 46, 2018
6DWZ
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HERMES TRANSPOSASE DELETION DIMER COMPLEX WITH (C/G) DNA
Descriptor:Hermes transposase, DNA (5'-D(*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), DNA (26-MER), ...
Authors:Dyda, F., Hickman, A.B.
Deposit date:2018-06-28
Release date:2018-09-19
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase.
Nucleic Acids Res., 46, 2018
6DX0
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HERMES TRANSPOSASE DELETION DIMER COMPLEX WITH (A/T) DNA
Descriptor:Hermes transposase, DNA (5'-D(*AP*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), DNA (25-MER), ...
Authors:Dyda, F., Voth, A.R., Hickman, A.B.
Deposit date:2018-06-28
Release date:2018-09-19
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase.
Nucleic Acids Res., 46, 2018
1AER
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DOMAIN III OF PSEUDOMONAS AERUGINOSA EXOTOXIN COMPLEXED WITH BETA-TAD
Descriptor:EXOTOXIN A, BETA-METHYLENE-THIAZOLE-4-CARBOXYAMIDE-ADENINE DINUCLEOTIDE, 2-(1,5-DIDEOXYRIBOSE)-4-AMIDO-THIAZOLE, ...
Authors:Li, M., Dyda, F., Benhar, I., Pastan, I., Davies, D.R.
Deposit date:1995-12-11
Release date:1996-06-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the catalytic domain of Pseudomonas exotoxin A complexed with a nicotinamide adenine dinucleotide analog: implications for the activation process and for ADP ribosylation
Proc.Natl.Acad.Sci.USA, 93, 1996
1BIS
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HIV-1 INTEGRASE CORE DOMAIN
Descriptor:HIV-1 INTEGRASE
Authors:Goldgur, Y., Dyda, F., Hickman, A.B., Jenkins, T.M., Craigie, R., Davies, D.R.
Deposit date:1998-06-19
Release date:1998-08-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium.
Proc.Natl.Acad.Sci.USA, 95, 1998
1BIU
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HIV-1 INTEGRASE CORE DOMAIN COMPLEXED WITH MG++
Descriptor:HIV-1 INTEGRASE, MAGNESIUM ION
Authors:Goldgur, Y., Dyda, F., Hickman, A.B., Jenkins, T.M., Craigie, R., Davies, D.R.
Deposit date:1998-06-19
Release date:1998-08-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium.
Proc.Natl.Acad.Sci.USA, 95, 1998
1BIZ
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HIV-1 INTEGRASE CORE DOMAIN
Descriptor:HIV-1 INTEGRASE, CACODYLATE ION
Authors:Goldgur, Y., Dyda, F., Hickman, A.B., Jenkins, T.M., Craigie, R., Davies, D.R.
Deposit date:1998-06-21
Release date:1998-08-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium.
Proc.Natl.Acad.Sci.USA, 95, 1998
1RZ9
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CRYSTAL STRUCTURE OF AAV REP COMPLEXED WITH THE REP-BINDING SEQUENCE
Descriptor:26-MER, Rep protein
Authors:Hickman, A.B., Ronning, D.R., Perez, Z.N., Kotin, R.M., Dyda, F.
Deposit date:2003-12-24
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The nuclease domain of adeno-associated virus rep coordinates replication initiation using two distinct DNA recognition interfaces.
Mol.Cell, 13, 2004
1T0F
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CRYSTAL STRUCTURE OF THE TNSA/TNSC(504-555) COMPLEX
Descriptor:Transposon Tn7 transposition protein tnsA, Transposon Tn7 transposition protein tnsC, MAGNESIUM ION, ...
Authors:Ronning, D.R., Li, Y., Perez, Z.N., Ross, P.D., Hickman, A.B., Craig, N.L., Dyda, F.
Deposit date:2004-04-08
Release date:2004-11-09
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The carboxy-terminal portion of TnsC activates the Tn7 transposase through a specific interaction with TnsA.
Embo J., 23, 2004
1A30
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HIV-1 PROTEASE COMPLEXED WITH A TRIPEPTIDE INHIBITOR
Descriptor:HIV-1 PROTEASE, TRIPEPTIDE GLU-ASP-LEU
Authors:Louis, J.M., Dyda, F., Nashed, N.T., Kimmel, A.R., Davies, D.R.
Deposit date:1998-01-27
Release date:1998-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Hydrophilic peptides derived from the transframe region of Gag-Pol inhibit the HIV-1 protease.
Biochemistry, 37, 1998
1AIH
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CATALYTIC DOMAIN OF BACTERIOPHAGE HP1 INTEGRASE
Descriptor:HP1 INTEGRASE, SULFATE ION, MAGNESIUM ION
Authors:Hickman, A.B., Waninger, S., Scocca, J.J., Dyda, F.
Deposit date:1997-04-17
Release date:1997-08-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular organization in site-specific recombination: the catalytic domain of bacteriophage HP1 integrase at 2.7 A resolution.
Cell(Cambridge,Mass.), 89, 1997
1B6B
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MELATONIN BIOSYNTHESIS: THE STRUCTURE OF SEROTONIN N-ACETYLTRANSFERASE AT 2.5 A RESOLUTION SUGGESTS A CATALYTIC MECHANISM
Descriptor:PROTEIN (ARYLALKYLAMINE N-ACETYLTRANSFERASE)
Authors:Hickman, A.B., Klein, D.C., Dyda, F.
Deposit date:1999-01-13
Release date:2000-01-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Melatonin biosynthesis: the structure of serotonin N-acetyltransferase at 2.5 A resolution suggests a catalytic mechanism.
Mol.Cell, 3, 1999
1CJW
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SEROTONIN N-ACETYLTRANSFERASE COMPLEXED WITH A BISUBSTRATE ANALOG
Descriptor:PROTEIN (SEROTONIN N-ACETYLTRANSFERASE), COA-S-ACETYL TRYPTAMINE
Authors:Hickman, A.B., Namboodiri, M.A.A., Klein, D.C., Dyda, F.
Deposit date:1999-04-19
Release date:1999-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structural basis of ordered substrate binding by serotonin N-acetyltransferase: enzyme complex at 1.8 A resolution with a bisubstrate analog.
Cell(Cambridge,Mass.), 97, 1999
1DMA
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DOMAIN III OF PSEUDOMONAS AERUGINOSA EXOTOXIN COMPLEXED WITH NICOTINAMIDE AND AMP
Descriptor:EXOTOXIN A, NICOTINAMIDE, ADENOSINE MONOPHOSPHATE
Authors:Li, M., Dyda, F., Benhar, I., Pastan, I., Davies, D.
Deposit date:1995-04-28
Release date:1995-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of Pseudomonas aeruginosa exotoxin domain III with nicotinamide and AMP: conformational differences with the intact exotoxin.
Proc.Natl.Acad.Sci.USA, 92, 1995
1F1Z
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TNSA, A CATALYTIC COMPONENT OF THE TN7 TRANSPOSITION SYSTEM
Descriptor:TNSA ENDONUCLEASE, MAGNESIUM ION, CHLORIDE ION
Authors:Hickman, A.B., Li, Y., Mathew, S.V., May, E.W., Craig, N.L., Dyda, F.
Deposit date:2000-05-21
Release date:2000-06-28
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Unexpected structural diversity in DNA recombination: the restriction endonuclease connection.
Mol.Cell, 5, 2000
1IB1
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CRYSTAL STRUCTURE OF THE 14-3-3 ZETA:SEROTONIN N-ACETYLTRANSFERASE COMPLEX
Descriptor:14-3-3 ZETA ISOFORM, SEROTONIN N-ACETYLTRANSFERASE, COA-S-ACETYL TRYPTAMINE
Authors:Obsil, T., Ghirlando, R., Klein, D.C., Ganguly, S., Dyda, F.
Deposit date:2001-03-26
Release date:2001-05-02
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the 14-3-3zeta:serotonin N-acetyltransferase complex. a role for scaffolding in enzyme regulation.
Cell(Cambridge,Mass.), 105, 2001
1M55
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CATALYTIC DOMAIN OF THE ADENO ASSOCIATED VIRUS TYPE 5 REP PROTEIN
Descriptor:Rep protein, ZINC ION, CHLORIDE ION
Authors:Hickman, A.B., Ronning, D.R., Kotin, R.M., Dyda, F.
Deposit date:2002-07-08
Release date:2002-08-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural unity among viral origin binding proteins: crystal structure of the nuclease domain of adeno-associated virus Rep.
Mol.Cell, 10, 2002
1MPE
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ENSEMBLE OF 20 STRUCTURES OF THE TETRAMERIC MUTANT OF THE B1 DOMAIN OF STREPTOCOCCAL PROTEIN G
Descriptor:Immunoglobulin G binding protein G
Authors:Frank, M.K., Dyda, F., Dobrodumov, A., Gronenborn, A.M.
Deposit date:2002-09-12
Release date:2002-10-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Core mutations switch monomeric protein GB1 into an intertwined tetramer.
Nat.Struct.Biol., 9, 2002
1MVK
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X-RAY STRUCTURE OF THE TETRAMERIC MUTANT OF THE B1 DOMAIN OF STREPTOCOCCAL PROTEIN G
Descriptor:Immunoglobulin G binding protein G, SULFATE ION
Authors:Frank, M.K., Dyda, F., Dobrodumov, A., Gronenborn, A.M.
Deposit date:2002-09-25
Release date:2002-10-30
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Core mutations switch monomeric protein GB1 into an intertwined tetramer.
Nat.Struct.Biol., 9, 2002
1YQV
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THE CRYSTAL STRUCTURE OF THE ANTIBODY FAB HYHEL5 COMPLEX WITH LYSOZYME AT 1.7A RESOLUTION
Descriptor:HyHEL-5 Antibody Light Chain, HyHEL-5 Antibody Heavy Chain, Hen Egg White Lysozyme
Authors:Cohen, G.H., Silverton, E.W., Padlan, E.A., Dyda, F., Wibbenmeyer, J.A., Wilson, R.C., Davies, D.R.
Deposit date:2005-02-02
Release date:2005-04-26
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Water molecules in the antibody-antigen interface of the structure of the Fab HyHEL-5-lysozyme complex at 1.7 A resolution: comparison with results from isothermal titration calorimetry.
Acta Crystallogr.,Sect.D, 61, 2005
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