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2Y2F
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Crystal structure of Yersinia pestis YopH in complex with an aminooxy- containing platform compound for inhibitor design
Descriptor: PROTEIN-TYROSINE PHOSPHATASE YOPH, [4-[3-(DIFLUORO-PHOSPHONO-METHYL)PHENYL]PHENYL]METHOXYAZANIUM
Authors:Lountos, G.T, Bahta, M, Dyas, B, Ulrich, R.G, Waugh, D.S, Burke, T.R.
Deposit date:2010-12-14
Release date:2011-03-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Utilization of Nitrophenylphosphates and Oxime-Based Ligation for the Development of Nanomolar Affinity Inhibitors of the Yersinia Pestis Outer Protein H (Yoph) Phosphatase.
J.Med.Chem., 54, 2011

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