Author results

2K2G
  • Download 2k2g
  • View 2k2g
Molmil generated image of 2k2g
SOLUTION STRUCTURE OF THE WILD-TYPE CATALYTIC DOMAIN OF HUMAN MATRIX METALLOPROTEINASE 12 (MMP-12) IN COMPLEX WITH A TIGHT-BINDING INHIBITOR
Descriptor:Macrophage metalloelastase, ZINC ION, N-(dibenzo[b,d]thiophen-3-ylsulfonyl)-L-valine
Authors:Markus, M.A., Dwyer, B., Wolfrom, S., Li, J., Li, W., Malakian, K., Wilhelm, J., Tsao, D.H.H.
Deposit date:2008-04-01
Release date:2008-05-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of wild-type human matrix metalloproteinase 12 (MMP-12) in complex with a tight-binding inhibitor.
J.Biomol.Nmr, 41, 2008
2ID5
  • Download 2id5
  • View 2id5
Molmil generated image of 2id5
CRYSTAL STRUCTURE OF THE LINGO-1 ECTODOMAIN
Descriptor:Leucine rich repeat neuronal 6A, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE
Authors:Mosyak, L., Wood, A., Dwyer, B., Johnson, M., Stahl, M.L., Somers, W.S.
Deposit date:2006-09-14
Release date:2006-09-26
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.698 Å)
Cite:The structure of the Lingo-1 ectodomain, a module implicated in central nervous system repair inhibition.
J.Biol.Chem., 281, 2006
6E7K
  • Download 6e7k
  • View 6e7k
Molmil generated image of 6e7k
STRUCTURE OF THE LIPOPROTEIN LIPASE GPIHBP1 COMPLEX THAT MEDIATES PLASMA TRIGLYCERIDE HYDROLYSIS
Descriptor:Lipoprotein lipase, Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1, CALCIUM ION, ...
Authors:Birrane, G., Meiyappan, M.
Deposit date:2018-07-26
Release date:2018-12-19
Last modified:2019-02-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the lipoprotein lipase-GPIHBP1 complex that mediates plasma triglyceride hydrolysis.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
2ZM3
  • Download 2zm3
  • View 2zm3
Molmil generated image of 2zm3
COMPLEX STRUCTURE OF INSULIN-LIKE GROWTH FACTOR RECEPTOR AND ISOQUINOLINEDIONE INHIBITOR
Descriptor:Insulin-like growth factor 1 receptor, (4Z)-6-bromo-4-({[4-(pyrrolidin-1-ylmethyl)phenyl]amino}methylidene)isoquinoline-1,3(2H,4H)-dione
Authors:Xu, W., Mayer, S.C., Boschelli, F., Johnson, M., Dwyer, B.
Deposit date:2008-04-10
Release date:2008-06-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Lead identification to generate isoquinolinedione inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment
Bioorg.Med.Chem.Lett., 18, 2008