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4RGM
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STRUCTURE OF STAPHYLOCOCCAL ENTEROTOXIN B BOUND TO THE NEUTRALIZING ANTIBODY 20B1
Descriptor:Enterotoxin type B, 20B1 light chain, 20B1 heavy chain
Authors:Franklin, M.C., Dutta, K., Varshney, A.K., Goger, M.J., Fries, B.C.
Deposit date:2014-09-30
Release date:2015-01-21
Last modified:2015-04-01
Method:X-RAY DIFFRACTION (2.689 Å)
Cite:Mechanisms mediating enhanced neutralization efficacy of staphylococcal enterotoxin B by combinations of monoclonal antibodies.
J.Biol.Chem., 290, 2015
4RGN
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STRUCTURE OF STAPHYLOCOCCAL ENTEROTOXIN B BOUND TO TWO NEUTRALIZING ANTIBODIES, 14G8 AND 6D3
Descriptor:Enterotoxin type B, 14G8 heavy chain, 14G8 light chain, ...
Authors:Franklin, M.C., Dutta, K., Varshney, A.K., Goger, M.J., Fries, B.C.
Deposit date:2014-09-30
Release date:2015-01-21
Last modified:2015-04-01
Method:X-RAY DIFFRACTION (2.698 Å)
Cite:Mechanisms mediating enhanced neutralization efficacy of staphylococcal enterotoxin B by combinations of monoclonal antibodies.
J.Biol.Chem., 290, 2015
4RGO
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STRUCTURE OF STAPHYLOCOCCAL ENTEROTOXIN B BOUND TO THE NEUTRALIZING ANTIBODY 14G8
Descriptor:Enterotoxin type B, 14G8 heavy chain, 14G8 light chain, ...
Authors:Franklin, M.C., Dutta, K., Varshney, A.K., Goger, M.J., Fries, B.C.
Deposit date:2014-09-30
Release date:2015-01-21
Last modified:2015-04-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mechanisms mediating enhanced neutralization efficacy of staphylococcal enterotoxin B by combinations of monoclonal antibodies.
J.Biol.Chem., 290, 2015
2GQC
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SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF RHOMBOID INTRAMEMBRANE PROTEASE FROM P. AERUGINOSA
Descriptor:Rhomboid Intramembrane Protease
Authors:Dutta, K., Del Rio, A., Chavez, J., Ubarretxena-Belandia, I., Ghose, R.
Deposit date:2006-04-20
Release date:2007-03-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure and dynamics of the N-terminal cytosolic domain of rhomboid intramembrane protease from Pseudomonas aeruginosa: insights into a functional role in intramembrane proteolysis.
J.Mol.Biol., 365, 2007
2LJ6
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SOLUTION STRUCTURE AND DNA-BINDING PROPERTIES OF THE PHOSPHOESTERASE DOMAIN OF DNA LIGASE D
Descriptor:Probable ATP-dependent DNA ligase
Authors:Dutta, K., Natarajan, A., Shuman, S., Ghose, R.
Deposit date:2011-09-06
Release date:2011-11-16
Last modified:2012-03-28
Method:SOLUTION NMR
Cite:Solution structure and DNA-binding properties of the phosphoesterase domain of DNA ligase D.
Nucleic Acids Res., 40, 2012
2LWD
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SOLUTION STRUCTURE OF SECOND CARD OF HUMAN RIG-I
Descriptor:Probable ATP-dependent RNA helicase DDX58
Authors:Dutta, K., Ferrage, F., Aggarwal, A.
Deposit date:2012-07-27
Release date:2012-10-31
Last modified:2012-12-26
Method:SOLUTION NMR
Cite:Structure and Dynamics of the Second CARD of Human RIG-I Provide Mechanistic Insights into Regulation of RIG-I Activation.
Structure, 20, 2012
2LWE
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SOLUTION STRUCTURE OF MUTANT (T170E) SECOND CARD OF HUMAN RIG-I
Descriptor:Probable ATP-dependent RNA helicase DDX58
Authors:Dutta, K., Ferrage, F., Aggarwal, A.
Deposit date:2012-07-27
Release date:2012-10-31
Last modified:2012-12-26
Method:SOLUTION NMR
Cite:Structure and Dynamics of the Second CARD of Human RIG-I Provide Mechanistic Insights into Regulation of RIG-I Activation.
Structure, 20, 2012
5J17
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SOLUTION STRUCTURE OF RAS BINDING DOMAIN (RBD) OF B-RAF
Descriptor:Serine/threonine-protein kinase B-raf
Authors:Dutta, K., Vasquez-Del Carpio, R., Aggarwal, A.K., Reddy, E.P.
Deposit date:2016-03-29
Release date:2016-10-05
Last modified:2017-09-20
Method:SOLUTION NMR
Cite:A Small Molecule RAS-Mimetic Disrupts RAS Association with Effector Proteins to Block Signaling.
Cell, 165, 2016
5J18
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SOLUTION STRUCTURE OF RAS BINDING DOMAIN (RBD) OF B-RAF COMPLEXED WITH RIGOSERTIB (COMPLEX I)
Descriptor:Serine/threonine-protein kinase B-raf, N-[2-methoxy-5-({[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl}methyl)phenyl]glycine
Authors:Dutta, K., Vasquez-Del Carpio, R., Aggarwal, A.K., Reddy, E.P.
Deposit date:2016-03-29
Release date:2016-05-04
Method:SOLUTION NMR
Cite:A Small Molecule RAS-Mimetic Disrupts RAS Association with Effector Proteins to Block Signaling.
Cell, 165, 2016
5J2R
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SOLUTION STRUCTURE OF RAS BINDING DOMAIN (RBD) OF B-RAF
Descriptor:Serine/threonine-protein kinase B-raf, N-[2-methoxy-5-({[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl}methyl)phenyl]glycine
Authors:Dutta, K., Vasquez-Del Carpio, R., Aggarwal, A.K., Reddy, E.P.
Deposit date:2016-03-29
Release date:2016-05-04
Method:SOLUTION NMR
Cite:A Small Molecule RAS-Mimetic Disrupts RAS Association with Effector Proteins to Block Signaling.
Cell, 165, 2016
5TVZ
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SOLUTION NMR STRUCTURE OF SACCHAROMYCES CEREVISIAE POM152 IG-LIKE REPEAT, RESIDUES 718-820
Descriptor:Nucleoporin POM152
Authors:Dutta, K., Sampathkumar, P., Cowburn, D., Almo, S.C., Rout, M.P., Fernandez-Martinez, J.
Deposit date:2016-11-10
Release date:2017-02-22
Last modified:2017-09-27
Method:SOLUTION NMR
Cite:Molecular Architecture of the Major Membrane Ring Component of the Nuclear Pore Complex.
Structure, 25, 2017
1IK1
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SOLUTION STRUCTURE OF AN RNA HAIRPIN FROM HRV-14
Descriptor:5'-R(*GP*GP*UP*AP*CP*UP*AP*UP*GP*UP*AP*CP*CP*A)-3'
Authors:Huang, H., Alexandrov, A., Chen, X., Barnes III, T.W., Zhang, H., Dutta, K., Pascal, S.M.
Deposit date:2001-05-01
Release date:2001-07-18
Last modified:2018-01-31
Method:SOLUTION NMR
Cite:Structure of an RNA hairpin from HRV-14.
Biochemistry, 40, 2001
1Z66
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NMR SOLUTION STRUCTURE OF DOMAIN III OF E-PROTEIN OF TICK-BORNE LANGAT FLAVIVIRUS (NO RDC RESTRAINTS)
Descriptor:Major envelope protein E
Authors:Mukherjee, M., Dutta, K., White, M.A., Cowburn, D., Fox, R.O.
Deposit date:2005-03-21
Release date:2006-03-28
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR solution structure and backbone dynamics of domain III of the E protein of tick-borne Langat flavivirus suggests a potential site for molecular recognition.
Protein Sci., 15, 2006
2GG1
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NMR SOLUTION STRUCTURE OF DOMAIN III OF THE E-PROTEIN OF TICK-BORNE LANGAT FLAVIVIRUS (INCLUDES RDC RESTRAINTS)
Descriptor:Genome polyprotein
Authors:Mukherjee, M., Dutta, K., White, M.A., Cowburn, D., Fox, R.O.
Deposit date:2006-03-23
Release date:2006-04-25
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR solution structure and backbone dynamics of domain III of the E protein of tick-borne Langat flavivirus suggests a potential site for molecular recognition.
Protein Sci., 15, 2006
2GGR
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SOLUTION STRUCTURE OF THE C-TERMINAL SH3 DOMAIN OF C-CRKII
Descriptor:Proto-oncogene C-crk
Authors:Muralidharan, V., Dutta, K., Muir, T.W., Cowburn, D.
Deposit date:2006-03-24
Release date:2006-08-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure and Folding Characteristics of the C-Terminal SH3 Domain of c-Crk-II
Biochemistry, 45, 2006
2K6X
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AUTOREGULATION OF A GROUP 1 BACTERIAL SIGMA FACTOR INVOLVES THE FORMATION OF A REGION 1.1- INDUCED COMPACTED STRUCTURE
Descriptor:RNA polymerase sigma factor rpoD
Authors:Schwartz, E.C., Shekhtman, A., Dutta, K., Pratt, M.R., Cowburn, D., Darst, S., Muir, T.W.
Deposit date:2008-07-28
Release date:2008-10-28
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Autoregulation of a Group 1 Bacterial Sigma Factor Involves the Formation of a Region 1.1 - Induced Compacted Structure
Chem.Biol., 15, 2008
2Q82
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CRYSTAL STRUCTURE OF CORE PROTEIN P7 FROM PSEUDOMONAS PHAGE PHI12. NORTHEAST STRUCTURAL GENOMICS TARGET OC1
Descriptor:Core protein P7
Authors:Benach, J., Eryilmaz, E., Su, M., Seetharaman, J., Wei, H., Gottlieb, P., Hunt, J.F., Ghose, R., Northeast Structural Genomics Consortium (NESG)
Deposit date:2007-06-08
Release date:2007-08-07
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structure and dynamics of the P7 protein from the bacteriophage phi 12.
J.Mol.Biol., 382, 2008
4J95
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CRYSTAL STRUCTURE OF FGF RECEPTOR 2 (FGFR2) KINASE DOMAIN HARBORING THE PATHOGENIC K659N MUTATION RESPONSIBLE FOR AN UNCLASSIFIED CRANIOSYNOSTOSIS SYNDROME IN SPACE GROUP C2.
Descriptor:Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION
Authors:Chen, H., Mohammadi, M.
Deposit date:2013-02-15
Release date:2013-08-07
Last modified:2016-12-28
Method:X-RAY DIFFRACTION (2.3767 Å)
Cite:Cracking the Molecular Origin of Intrinsic Tyrosine Kinase Activity through Analysis of Pathogenic Gain-of-Function Mutations.
Cell Rep, 4, 2013
4J96
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CRYSTAL STRUCTURE OF FGF RECEPTOR 2 (FGFR2) KINASE DOMAIN HARBORING THE PATHOGENIC GAIN-OF-FUNCTION K659M MUTATION IDENTIFIED IN CERVICAL CANCER.
Descriptor:Fibroblast growth factor receptor 2, SULFATE ION, CITRATE ANION, ...
Authors:Chen, H., Mohammadi, M.
Deposit date:2013-02-15
Release date:2013-08-07
Last modified:2016-12-28
Method:X-RAY DIFFRACTION (2.2972 Å)
Cite:Cracking the Molecular Origin of Intrinsic Tyrosine Kinase Activity through Analysis of Pathogenic Gain-of-Function Mutations.
Cell Rep, 4, 2013
4J97
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CRYSTAL STRUCTURE OF FGF RECEPTOR 2 (FGFR2) KINASE DOMAIN HARBORING THE PATHOGENIC GAIN-OF-FUNCTION K659E MUTATION IDENTIFIED IN ENDOMETRIAL CANCER.
Descriptor:Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION
Authors:Chen, H., Mohammadi, M.
Deposit date:2013-02-15
Release date:2013-08-07
Last modified:2016-12-28
Method:X-RAY DIFFRACTION (2.5482 Å)
Cite:Cracking the Molecular Origin of Intrinsic Tyrosine Kinase Activity through Analysis of Pathogenic Gain-of-Function Mutations.
Cell Rep, 4, 2013
4J98
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CRYSTAL STRUCTURE OF FGF RECEPTOR 2 (FGFR2) KINASE DOMAIN HARBORING THE GAIN-OF-FUNCTION K659Q MUTATION.
Descriptor:Fibroblast growth factor receptor 2, SULFATE ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
Authors:Huang, Z., Chen, H., Mohammadi, M.
Deposit date:2013-02-15
Release date:2013-08-07
Last modified:2016-12-28
Method:X-RAY DIFFRACTION (2.3067 Å)
Cite:Cracking the Molecular Origin of Intrinsic Tyrosine Kinase Activity through Analysis of Pathogenic Gain-of-Function Mutations.
Cell Rep, 4, 2013
4J99
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CRYSTAL STRUCTURE OF FGF RECEPTOR 2 (FGFR2) KINASE DOMAIN HARBORING THE GAIN-OF-FUNCTION K659T MUTATION.
Descriptor:Fibroblast growth factor receptor 2, SULFATE ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
Authors:Chen, H., Mohammadi, M.
Deposit date:2013-02-15
Release date:2013-08-07
Last modified:2016-12-28
Method:X-RAY DIFFRACTION (1.8474 Å)
Cite:Cracking the Molecular Origin of Intrinsic Tyrosine Kinase Activity through Analysis of Pathogenic Gain-of-Function Mutations.
Cell Rep, 4, 2013