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2J6E
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CRYSTAL STRUCTURE OF AN AUTOIMMUNE COMPLEX BETWEEN A HUMAN IGM RHEUMATOID FACTOR AND IGG1 FC REVEALS A NOVEL FC EPITOPE AND EVIDENCE FOR AFFINITY MATURATION
Descriptor:IG GAMMA-1 CHAIN C REGION, IGM, CADMIUM ION, ...
Authors:Duquerroy, S., Stura, E.A., Bressanelli, S., Browne, H., Beale, D., Hamon, M., Casali, P., Vaney, M.-C., Rey, F.A., Sutton, B.J., Taussig, M.J.
Deposit date:2006-09-28
Release date:2007-04-10
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of a Human Autoimmune Complex between Igm Rheumatoid Factor Rf61 and Igg1 Fc Reveals a Novel Epitope and Evidence for Affinity Maturation.
J.Mol.Biol., 368, 2007
2VF1
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X-RAY CRYSTALLOGRAPHIC STRUCTURE OF THE PICOBIRNAVIRUS CAPSID
Descriptor:CAPSID PROTEIN
Authors:Duquerroy, S., Da Costa, B., Vigouroux, A., Lepault, J., Navaza, J., Delmas, B., Rey, F.A.
Deposit date:2007-10-29
Release date:2008-12-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:The Picobirnavirus Crystal Structure Provides Functional Insights Into Virion Assembly and Cell Entry.
Embo J., 28, 2009
1WYY
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POST-FUSION HAIRPIN CONFORMATION OF THE SARS CORONAVIRUS SPIKE GLYCOPROTEIN
Descriptor:E2 Glycoprotein, CHLORIDE ION
Authors:Duquerroy, S., Vigouroux, A., Rottier, P.J.M., Rey, F.A., Bosch, B.J.
Deposit date:2005-02-18
Release date:2005-05-17
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Central ions and lateral asparagine/glutamine zippers stabilize the post-fusion hairpin conformation of the SARS coronavirus spike glycoprotein
Virology, 335, 2005
1PDY
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X-RAY STRUCTURE AND CATALYTIC MECHANISM OF LOBSTER ENOLASE
Descriptor:ENOLASE, SULFATE ION
Authors:Janin, J., Duquerroy, S., Camus, C., Le Bras, G.
Deposit date:1995-06-05
Release date:1995-11-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:X-ray structure and catalytic mechanism of lobster enolase.
Biochemistry, 34, 1995
1PDZ
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X-RAY STRUCTURE AND CATALYTIC MECHANISM OF LOBSTER ENOLASE
Descriptor:ENOLASE, 2-PHOSPHOGLYCOLIC ACID, MANGANESE (II) ION
Authors:Janin, J., Duquerroy, S., Camus, C., Le Bras, G.
Deposit date:1995-06-05
Release date:1995-11-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:X-ray structure and catalytic mechanism of lobster enolase.
Biochemistry, 34, 1995
5N09
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CRYSTAL STRUCTURE OF L107C/A313C COVALENTLY LINKED DENGUE 2 VIRUS ENVELOPE GLYCOPROTEIN DIMER IN COMPLEX WITH THE FAB FRAGMENT OF THE BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 A11
Descriptor:Envelope Glycoprotein E, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 A11 - Heavy chain, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 A11 - Light chain, ...
Authors:Duquerroy, S., Rouvinski, A., Guardado-Calvo, P., Vaney, M.-C., Sharma, A., Rey, F.
Deposit date:2017-02-02
Release date:2017-06-07
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Covalently linked dengue virus envelope glycoprotein dimers reduce exposure of the immunodominant fusion loop epitope.
Nat Commun, 8, 2017
4BWN
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NEMO CC2-LZ DOMAIN
Descriptor:NF-KAPPA-B ESSENTIAL MODULATOR
Authors:Dubosclard, V., Duquerroy, S., Fontan, E., Agou, F.
Deposit date:2013-07-03
Release date:2014-07-23
Last modified:2014-10-29
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:High-Resolution of Crystal Structure of the Human Cc2-Lz Domain of Nemo by Protein Engineering
To be Published
4ACQ
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ALPHA-2 MACROGLOBULIN
Descriptor:ALPHA-2-MACROGLOBULIN, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE
Authors:Marrero, A., Duquerroy, S., Trapani, S., Goulas, T., Guevara, T., Andersen, G.R., Navaza, J., Sottrup-Jensen, L., Gomis-Ruth, F.X.
Deposit date:2011-12-17
Release date:2012-02-22
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:The crystal structure of human alpha 2-macroglobulin reveals a unique molecular cage.
Angew. Chem. Int. Ed. Engl., 51, 2012
4UC6
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N-TERMINAL GLOBULAR DOMAIN OF THE RSV NUCLEOPROTEIN
Descriptor:NUCLEOPROTEIN, SULFATE ION
Authors:Ouizougun-Oubari, M., Pereira, N., Tarus, B., Galloux, M., Tortorici, M.-A., Hoos, S., Baron, B., England, P., Bontems, F., Rey, F.A., Eleouet, J.-F., Sizun, C., Slama-Schwok, A., Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UC7
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N-TERMINAL GLOBULAR DOMAIN OF THE RSV NUCLEOPROTEIN
Descriptor:NUCLEOPROTEIN, SULFATE ION
Authors:Ouizougun-Oubari, M., Pereira, N., Tarus, B., Galloux, M., Tortorici, M.-A., Hoos, S., Baron, B., England, P., Bontems, F., Rey, F.A., Eleouet, J.-F., Sizun, C., Slama-Schwok, A., Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UC8
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N-TERMINAL GLOBULAR DOMAIN OF THE RSV NUCLEOPROTEIN IN COMPLEX WITH C- TERMINAL PHENYLALANINE OF THE PHOSPHOPROTEIN
Descriptor:NUCLEOPROTEIN, PHENYLALANINE, SULFATE ION, ...
Authors:Ouizougun-Oubari, M., Pereira, N., Tarus, B., Galloux, M., Tortorici, M.-A., Hoos, S., Baron, B., England, P., Bontems, F., Rey, F.A., Eleouet, J.-F., Sizun, C., Slama-Schwok, A., Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UC9
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N-TERMINAL GLOBULAR DOMAIN OF THE RSV NUCLEOPROTEIN IN COMPLEX WITH C- TERMINAL DIPEPTIDE OF THE PHOSPHOPROTEIN
Descriptor:NUCLEOPROTEIN, SULFATE ION, ASPARTIC ACID, ...
Authors:Ouizougun-Oubari, M., Pereira, N., Tarus, B., Galloux, M., Tortorici, M.-A., Hoos, S., Baron, B., England, P., Bontems, F., Rey, F.A., Eleouet, J.-F., Sizun, C., Slama-Schwok, A., Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UCA
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N-TERMINAL GLOBULAR DOMAIN OF THE RSV NUCLEOPROTEIN IN COMPLEX WITH C- TERMINAL PEPTIDE OF THE PHOSPHOPROTEIN
Descriptor:NUCLEOPROTEIN, PHOSPHOSPROTEIN, SULFATE ION
Authors:Ouizougun-Oubari, M., Pereira, N., Tarus, B., Galloux, M., Tortorici, M.-A., Hoos, S., Baron, B., England, P., Bontems, F., Rey, F.A., Eleouet, J.-F., Sizun, C., Slama-Schwok, A., Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UCB
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N-TERMINAL GLOBULAR DOMAIN OF THE RSV NUCLEOPROTEIN IN COMPLEX WITH C- TERMINAL PEPTIDE OF THE PHOSPHOPROTEIN
Descriptor:NUCLEOPROTEIN, PHOSPHOSPROTEIN, SULFATE ION
Authors:Ouizougun-Oubari, M., Pereira, N., Tarus, B., Galloux, M., Tortorici, M.-A., Hoos, S., Baron, B., England, P., Bontems, F., Rey, F.A., Eleouet, J.-F., Sizun, C., Slama-Schwok, A., Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UCC
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N-TERMINAL GLOBULAR DOMAIN OF THE RSV NUCLEOPROTEIN IN COMPLEX WITH THE NUCLEOPROTEIN PHOSPHOPROTEIN INTERACTION INHIBITOR M76
Descriptor:NUCLEOPROTEIN, 1-[(2,4-dichlorophenyl)methyl]pyrazole-3,5-dicarboxylic acid
Authors:Ouizougun-Oubari, M., Pereira, N., Tarus, B., Galloux, M., Tortorici, M.-A., Hoos, S., Baron, B., England, P., Bontems, F., Rey, F.A., Eleouet, J.-F., Sizun, C., Slama-Schwok, A., Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UCD
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N-TERMINAL GLOBULAR DOMAIN OF THE RSV NUCLEOPROTEIN IN COMPLEX WITH THE NUCLEOPROTEIN PHOSPHOPROTEIN INTERACTION INHIBITOR M81
Descriptor:NUCLEOPROTEIN, 1-[(2-chlorophenyl)methyl]pyrazole-3,5-dicarboxylic acid, SULFATE ION
Authors:Ouizougun-Oubari, M., Pereira, N., Tarus, B., Galloux, M., Tortorici, M.-A., Hoos, S., Baron, B., England, P., Bontems, F., Rey, F.A., Eleouet, J.-F., Sizun, C., Slama-Schwok, A., Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UCE
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N-TERMINAL GLOBULAR DOMAIN OF THE RSV NUCLEOPROTEIN IN COMPLEX WITH THE NUCLEOPROTEIN PHOSPHOPROTEIN INTERACTION INHIBITOR M72
Descriptor:NUCLEOPROTEIN, 1-[(4-fluorophenyl)methyl]pyrazole-3,5-dicarboxylic acid, SULFATE ION
Authors:Ouizougun-Oubari, M., Pereira, N., Tarus, B., Galloux, M., Tortorici, M.-A., Hoos, S., Baron, B., England, P., Bontems, F., Rey, F.A., Eleouet, J.-F., Sizun, C., Slama-Schwok, A., Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UT6
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CRYSTAL STRUCTURE OF DENGUE 2 VIRUS ENVELOPE GLYCOPROTEIN IN COMPLEX WITH THE FAB FRAGMENT OF THE BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 B7
Descriptor:ENVELOPE GLYCOPROTEIN E, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 B7, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2, ...
Authors:Rouvinski, A., Guardado-Calvo, P., Barba-Spaeth, G., Duquerroy, S., Vaney, M.C., Rey, F.A.
Deposit date:2014-07-18
Release date:2015-01-28
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Recognition Determinants of Broadly Neutralizing Human Antibodies Against Dengue Viruses.
Nature, 520, 2015
4UT7
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CRYSTAL STRUCTURE OF THE SCFV FRAGMENT OF THE BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 A11
Descriptor:BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 A11
Authors:Rouvinski, A., Guardado-Calvo, P., Barba-Spaeth, G., Duquerroy, S., Vaney, M.C., Rey, F.A.
Deposit date:2014-07-18
Release date:2015-01-28
Last modified:2015-04-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Recognition Determinants of Broadly Neutralizing Human Antibodies Against Dengue Viruses.
Nature, 520, 2015
4UT9
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CRYSTAL STRUCTURE OF DENGUE 2 VIRUS ENVELOPE GLYCOPROTEIN DIMER IN COMPLEX WITH THE SCFV FRAGMENT OF THE BROADLY NEUTRALIZING HUMAN ANTIBODY EDE1 C10
Descriptor:ENVELOPE GLYCOPROTEIN E, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE1 C10, N-ACETYL-D-GLUCOSAMINE
Authors:Rouvinski, A., Guardado-Calvo, P., Barba-Spaeth, G., Duquerroy, S., Vaney, M.C., Rey, F.A.
Deposit date:2014-07-18
Release date:2015-01-28
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Recognition Determinants of Broadly Neutralizing Human Antibodies Against Dengue Viruses.
Nature, 520, 2015
4UTA
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CRYSTAL STRUCTURE OF DENGUE 2 VIRUS ENVELOPE GLYCOPROTEIN IN COMPLEX WITH THE FAB FRAGMENT OF THE BROADLY NEUTRALIZING HUMAN ANTIBODY EDE1 C8
Descriptor:ENVELOPE GLYCOPROTEIN E, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE1 C8 HEAVY CHAIN, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE1 C8 LIGHT CHAIN, ...
Authors:Rouvinski, A., Guardado-Calvo, P., Barba-Spaeth, G., Duquerroy, S., Vaney, M.C., Rey, F.A.
Deposit date:2014-07-18
Release date:2015-01-28
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Recognition Determinants of Broadly Neutralizing Human Antibodies Against Dengue Viruses.
Nature, 520, 2015
4UTB
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CRYSTAL STRUCTURE OF DENGUE 2 VIRUS ENVELOPE GLYCOPROTEIN IN COMPLEX WITH THE FAB FRAGMENT OF THE BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 A11
Descriptor:ENVELOPE GLYCOPROTEIN E, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 A11, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Rouvinski, A., Guardado-Calvo, P., Barba-Spaeth, G., Duquerroy, S., Vaney, M.C., Rey, F.A.
Deposit date:2014-07-18
Release date:2015-01-28
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (3.85 Å)
Cite:Recognition Determinants of Broadly Neutralizing Human Antibodies Against Dengue Viruses.
Nature, 520, 2015
4UTC
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CRYSTAL STRUCTURE OF DENGUE 2 VIRUS ENVELOPE GLYCOPROTEIN
Descriptor:ENVELOPE GLYCOPROTEIN E, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
Authors:Kikuti, C., Rouvinski, A., Guardado-Calvo, P., Barba-Spaeth, G., Duquerroy, S., Vaney, M.C., Rey, F.A.
Deposit date:2014-07-18
Release date:2015-01-28
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:Recognition Determinants of Broadly Neutralizing Human Antibodies Against Dengue Viruses.
Nature, 520, 2015
2BUO
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HIV-1 CAPSID C-TERMINAL DOMAIN IN COMPLEX WITH AN INHIBITOR OF PARTICLE ASSEMBLY
Descriptor:HIV-1 CAPSID PROTEIN, INHIBITOR OF CAPSID ASSEMBLY, ACETIC ACID
Authors:Ternois, F., Sticht, J., Duquerroy, S., Krausslich, H.-G., Rey, F.A.
Deposit date:2005-06-17
Release date:2005-07-21
Last modified:2017-02-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The HIV-1 Capsid Protein C-Terminal Domain in Complex with a Virus Assembly Inhibitor
Nat.Struct.Mol.Biol., 12, 2005
2XFB
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CHIKUNGUNYA E1 E2 ENVELOPE GLYCOPROTEINS FITTED IN SINDBIS VIRUS CRYO- EM MAP
Descriptor:E1 ENVELOPE GLYCOPROTEIN, E2 ENVELOPE GLYCOPROTEIN
Authors:Voss, J.E., Vaney, M.C., Duquerroy, S., Rey, F.A.
Deposit date:2010-05-21
Release date:2010-11-24
Last modified:2013-03-20
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Glycoprotein Organization of Chikungunya Virus Particles Revealed by X-Ray Crystallography
Nature, 468, 2010
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