Author results

6RX1
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CRYSTAL STRUCTURE OF HUMAN SYNCYTIN 1 IN POST-FUSION CONFORMATION
Descriptor:Syncytin-1, GLYCEROL, CHLORIDE ION
Authors:Ruigrok, K., Backovic, M., Vaney, M.C., Rey, F.A.
Deposit date:2019-06-07
Release date:2019-11-20
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray Structures of the Post-fusion 6-Helix Bundle of the Human Syncytins and their Functional Implications.
J.Mol.Biol., 431, 2019
6RX3
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CRYSTAL STRUCTURE OF HUMAN SYNCYTIN 2 IN POST-FUSION CONFORMATION
Descriptor:Syncytin-2, CHLORIDE ION
Authors:Ruigrok, K., Backovic, M., Vaney, M.C., Rey, F.A.
Deposit date:2019-06-07
Release date:2019-11-20
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:X-ray Structures of the Post-fusion 6-Helix Bundle of the Human Syncytins and their Functional Implications.
J.Mol.Biol., 431, 2019
6EPK
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CRYSTAL STRUCTURE OF THE PRECURSOR MEMBRANE PROTEIN-ENVELOPE PROTEIN HETERODIMER FROM THE YELLOW FEVER VIRUS
Descriptor:Envelope protein E, Precursor Membrane Protein, SULFATE ION, ...
Authors:Rey, F.A., Duquerroy, S., Crampon, E., Barba-Spaeth, G.
Deposit date:2017-10-11
Release date:2018-10-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:CRYSTAL STRUCTURE OF THE PRECURSOR MEMBRANE PROTEIN-ENVELOPE PROTEIN HETERODIMER FROM THE YELLOW FEVER VIRUS
To Be Published
5N09
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CRYSTAL STRUCTURE OF L107C/A313C COVALENTLY LINKED DENGUE 2 VIRUS ENVELOPE GLYCOPROTEIN DIMER IN COMPLEX WITH THE FAB FRAGMENT OF THE BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 A11
Descriptor:Envelope Glycoprotein E, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 A11 - Heavy chain, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 A11 - Light chain, ...
Authors:Duquerroy, S., Rouvinski, A., Guardado-Calvo, P., Vaney, M.-C., Sharma, A., Rey, F.
Deposit date:2017-02-02
Release date:2017-06-07
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Covalently linked dengue virus envelope glycoprotein dimers reduce exposure of the immunodominant fusion loop epitope.
Nat Commun, 8, 2017
5N0A
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CRYSTAL STRUCTURE OF A259C COVALENTLY LINKED DENGUE 2 VIRUS ENVELOPE GLYCOPROTEIN DIMER IN COMPLEX WITH THE FAB FRAGMENT OF THE BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 A11
Descriptor:Envelope Glycoprotein E, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 A11 HEAVY CHAIN, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 A11, ...
Authors:Vaney, M.C., Rouvinski, A., Guardado-Calvo, P., Sharma, A., Rey, F.A.
Deposit date:2017-02-02
Release date:2017-06-07
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Covalently linked dengue virus envelope glycoprotein dimers reduce exposure of the immunodominant fusion loop epitope.
Nat Commun, 8, 2017
5LBS
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STRUCTURAL BASIS OF ZIKA AND DENGUE VIRUS POTENT ANTIBODY CROSS-NEUTRALIZATION
Descriptor:envelope protein E, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE1 C8, 1,2-ETHANEDIOL, ...
Authors:Vaney, M.C., Rouvinski, A., Barba-Spaeth, G., Rey, F.A.
Deposit date:2016-06-17
Release date:2016-07-06
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Structural basis of potent Zika-dengue virus antibody cross-neutralization.
Nature, 536, 2016
5LBV
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STRUCTURAL BASIS OF ZIKA AND DENGUE VIRUS POTENT ANTIBODY CROSS-NEUTRALIZATION
Descriptor:envelope protein E, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Barba-Spaeth, G.
Deposit date:2016-06-17
Release date:2016-07-06
Last modified:2016-08-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of potent Zika-dengue virus antibody cross-neutralization.
Nature, 536, 2016
5A42
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CRYO-EM SINGLE PARTICLE 3D RECONSTRUCTION OF THE NATIVE CONFORMATION OF E. COLI ALPHA-2-MACROGLOBULIN (ECAM)
Descriptor:UNCHARACTERIZED LIPOPROTEIN YFHM
Authors:Garcia-Ferrer, I., Arede, P., Gomez-Blanco, J., Luque, D., Duquerroy, S., Caston, J.R., Goulas, T., Gomis-Ruth, F.X.
Deposit date:2015-06-04
Release date:2015-07-29
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (16 Å)
Cite:Structural and Functional Insights Into Escherichia Coli Alpha2- Macroglobulin Endopeptidase Snap-Trap Inhibition.
Proc.Natl.Acad.Sci.USA, 112, 2015
4ZJG
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CRYSTAL STRUCTURE OF NATIVE ALPHA-2-MACROGLOBULIN FROM ESCHERICHIA COLI SPANNING DOMAINS MG0-NIE-MG1.
Descriptor:alpha-2-Macroglobulin, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, ...
Authors:Garcia-Ferrer, I., Arede, P., Gomez-Blanco, J., Luque, D., Duquerroy, S., Caston, J.R., Goulas, T., Gomis-Ruth, X.F.
Deposit date:2015-04-29
Release date:2015-06-10
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and functional insights into Escherichia coli alpha 2-macroglobulin endopeptidase snap-trap inhibition.
Proc.Natl.Acad.Sci.USA, 112, 2015
4ZJH
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CRYSTAL STRUCTURE OF NATIVE ALPHA-2-MACROGLOBULIN FROM ESCHERICHIA COLI SPANNING DOMAINS NIE-MG1.
Descriptor:alpha-2-Macroglobulin, ACETATE ION, GLYCEROL
Authors:Garcia-Ferrer, I., Arede, P., Gomez-Blanco, J., Luque, D., Duquerroy, S., Caston, J.R., Goulas, T., Gomis-Ruth, X.F.
Deposit date:2015-04-29
Release date:2015-06-10
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and functional insights into Escherichia coli alpha 2-macroglobulin endopeptidase snap-trap inhibition.
Proc.Natl.Acad.Sci.USA, 112, 2015
4ZIQ
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CRYSTAL STRUCTURE OF TRYPSIN ACTIVATED ALPHA-2-MACROGLOBULIN FROM ESCHERICHIA COLI.
Descriptor:Uncharacterized lipoprotein YfhM, GLYCEROL, CHLORIDE ION
Authors:Garcia-Ferrer, I., Arede, P., Gomez-Blanco, J., Luque, D., Duquerroy, S., Caston, J.R., Goulas, T., Gomis-Ruth, X.F.
Deposit date:2015-04-28
Release date:2015-06-10
Last modified:2015-07-15
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural and functional insights into Escherichia coli alpha 2-macroglobulin endopeptidase snap-trap inhibition.
Proc.Natl.Acad.Sci.USA, 112, 2015
4ZIU
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CRYSTAL STRUCTURE OF NATIVE ALPHA-2-MACROGLOBULIN FROM ESCHERICHIA COLI SPANNING THE RESIDUES FROM DOMAIN MG7 TO THE C-TERMINUS.
Descriptor:Uncharacterized lipoprotein YfhM, NICKEL (II) ION, GLYCEROL
Authors:Garcia-Ferrer, I., Arede, P., Gomez-Blanco, J., Luque, D., Duquerroy, S., Caston, J.R., Goulas, T., Gomis-Ruth, X.F.
Deposit date:2015-04-28
Release date:2015-06-10
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and functional insights into Escherichia coli alpha 2-macroglobulin endopeptidase snap-trap inhibition.
Proc.Natl.Acad.Sci.USA, 112, 2015
4UC6
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N-TERMINAL GLOBULAR DOMAIN OF THE RSV NUCLEOPROTEIN
Descriptor:NUCLEOPROTEIN, SULFATE ION
Authors:Ouizougun-Oubari, M., Pereira, N., Tarus, B., Galloux, M., Tortorici, M.-A., Hoos, S., Baron, B., England, P., Bontems, F., Rey, F.A., Eleouet, J.-F., Sizun, C., Slama-Schwok, A., Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UC7
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N-TERMINAL GLOBULAR DOMAIN OF THE RSV NUCLEOPROTEIN
Descriptor:NUCLEOPROTEIN, SULFATE ION
Authors:Ouizougun-Oubari, M., Pereira, N., Tarus, B., Galloux, M., Tortorici, M.-A., Hoos, S., Baron, B., England, P., Bontems, F., Rey, F.A., Eleouet, J.-F., Sizun, C., Slama-Schwok, A., Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UC8
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N-TERMINAL GLOBULAR DOMAIN OF THE RSV NUCLEOPROTEIN IN COMPLEX WITH C- TERMINAL PHENYLALANINE OF THE PHOSPHOPROTEIN
Descriptor:NUCLEOPROTEIN, PHENYLALANINE, SULFATE ION, ...
Authors:Ouizougun-Oubari, M., Pereira, N., Tarus, B., Galloux, M., Tortorici, M.-A., Hoos, S., Baron, B., England, P., Bontems, F., Rey, F.A., Eleouet, J.-F., Sizun, C., Slama-Schwok, A., Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UC9
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N-TERMINAL GLOBULAR DOMAIN OF THE RSV NUCLEOPROTEIN IN COMPLEX WITH C- TERMINAL DIPEPTIDE OF THE PHOSPHOPROTEIN
Descriptor:NUCLEOPROTEIN, SULFATE ION, ASPARTIC ACID, ...
Authors:Ouizougun-Oubari, M., Pereira, N., Tarus, B., Galloux, M., Tortorici, M.-A., Hoos, S., Baron, B., England, P., Bontems, F., Rey, F.A., Eleouet, J.-F., Sizun, C., Slama-Schwok, A., Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UCA
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N-TERMINAL GLOBULAR DOMAIN OF THE RSV NUCLEOPROTEIN IN COMPLEX WITH C- TERMINAL PEPTIDE OF THE PHOSPHOPROTEIN
Descriptor:NUCLEOPROTEIN, PHOSPHOSPROTEIN, SULFATE ION
Authors:Ouizougun-Oubari, M., Pereira, N., Tarus, B., Galloux, M., Tortorici, M.-A., Hoos, S., Baron, B., England, P., Bontems, F., Rey, F.A., Eleouet, J.-F., Sizun, C., Slama-Schwok, A., Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UCB
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N-TERMINAL GLOBULAR DOMAIN OF THE RSV NUCLEOPROTEIN IN COMPLEX WITH C- TERMINAL PEPTIDE OF THE PHOSPHOPROTEIN
Descriptor:NUCLEOPROTEIN, PHOSPHOSPROTEIN, SULFATE ION
Authors:Ouizougun-Oubari, M., Pereira, N., Tarus, B., Galloux, M., Tortorici, M.-A., Hoos, S., Baron, B., England, P., Bontems, F., Rey, F.A., Eleouet, J.-F., Sizun, C., Slama-Schwok, A., Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UCC
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N-TERMINAL GLOBULAR DOMAIN OF THE RSV NUCLEOPROTEIN IN COMPLEX WITH THE NUCLEOPROTEIN PHOSPHOPROTEIN INTERACTION INHIBITOR M76
Descriptor:NUCLEOPROTEIN, 1-[(2,4-dichlorophenyl)methyl]pyrazole-3,5-dicarboxylic acid
Authors:Ouizougun-Oubari, M., Pereira, N., Tarus, B., Galloux, M., Tortorici, M.-A., Hoos, S., Baron, B., England, P., Bontems, F., Rey, F.A., Eleouet, J.-F., Sizun, C., Slama-Schwok, A., Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UCD
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N-TERMINAL GLOBULAR DOMAIN OF THE RSV NUCLEOPROTEIN IN COMPLEX WITH THE NUCLEOPROTEIN PHOSPHOPROTEIN INTERACTION INHIBITOR M81
Descriptor:NUCLEOPROTEIN, 1-[(2-chlorophenyl)methyl]pyrazole-3,5-dicarboxylic acid, SULFATE ION
Authors:Ouizougun-Oubari, M., Pereira, N., Tarus, B., Galloux, M., Tortorici, M.-A., Hoos, S., Baron, B., England, P., Bontems, F., Rey, F.A., Eleouet, J.-F., Sizun, C., Slama-Schwok, A., Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UCE
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N-TERMINAL GLOBULAR DOMAIN OF THE RSV NUCLEOPROTEIN IN COMPLEX WITH THE NUCLEOPROTEIN PHOSPHOPROTEIN INTERACTION INHIBITOR M72
Descriptor:NUCLEOPROTEIN, 1-[(4-fluorophenyl)methyl]pyrazole-3,5-dicarboxylic acid, SULFATE ION
Authors:Ouizougun-Oubari, M., Pereira, N., Tarus, B., Galloux, M., Tortorici, M.-A., Hoos, S., Baron, B., England, P., Bontems, F., Rey, F.A., Eleouet, J.-F., Sizun, C., Slama-Schwok, A., Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UT6
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CRYSTAL STRUCTURE OF DENGUE 2 VIRUS ENVELOPE GLYCOPROTEIN IN COMPLEX WITH THE FAB FRAGMENT OF THE BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 B7
Descriptor:ENVELOPE GLYCOPROTEIN E, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 B7, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2, ...
Authors:Rouvinski, A., Guardado-Calvo, P., Barba-Spaeth, G., Duquerroy, S., Vaney, M.C., Rey, F.A.
Deposit date:2014-07-18
Release date:2015-01-28
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Recognition Determinants of Broadly Neutralizing Human Antibodies Against Dengue Viruses.
Nature, 520, 2015
4UT7
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CRYSTAL STRUCTURE OF THE SCFV FRAGMENT OF THE BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 A11
Descriptor:BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 A11
Authors:Rouvinski, A., Guardado-Calvo, P., Barba-Spaeth, G., Duquerroy, S., Vaney, M.C., Rey, F.A.
Deposit date:2014-07-18
Release date:2015-01-28
Last modified:2015-04-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Recognition Determinants of Broadly Neutralizing Human Antibodies Against Dengue Viruses.
Nature, 520, 2015
4UT9
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CRYSTAL STRUCTURE OF DENGUE 2 VIRUS ENVELOPE GLYCOPROTEIN DIMER IN COMPLEX WITH THE SCFV FRAGMENT OF THE BROADLY NEUTRALIZING HUMAN ANTIBODY EDE1 C10
Descriptor:ENVELOPE GLYCOPROTEIN E, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE1 C10, N-ACETYL-D-GLUCOSAMINE
Authors:Rouvinski, A., Guardado-Calvo, P., Barba-Spaeth, G., Duquerroy, S., Vaney, M.C., Rey, F.A.
Deposit date:2014-07-18
Release date:2015-01-28
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Recognition Determinants of Broadly Neutralizing Human Antibodies Against Dengue Viruses.
Nature, 520, 2015
4UTA
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CRYSTAL STRUCTURE OF DENGUE 2 VIRUS ENVELOPE GLYCOPROTEIN IN COMPLEX WITH THE FAB FRAGMENT OF THE BROADLY NEUTRALIZING HUMAN ANTIBODY EDE1 C8
Descriptor:ENVELOPE GLYCOPROTEIN E, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE1 C8 HEAVY CHAIN, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE1 C8 LIGHT CHAIN, ...
Authors:Rouvinski, A., Guardado-Calvo, P., Barba-Spaeth, G., Duquerroy, S., Vaney, M.C., Rey, F.A.
Deposit date:2014-07-18
Release date:2015-01-28
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Recognition Determinants of Broadly Neutralizing Human Antibodies Against Dengue Viruses.
Nature, 520, 2015
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