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4OX9
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CRYSTAL STRUCTURE OF THE AMINOGLYCOSIDE RESISTANCE METHYLTRANSFERASE NPMA BOUND TO THE 30S RIBOSOMAL SUBUNIT
Descriptor:30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, 30S ribosomal protein S5, 30S ribosomal protein S6, 30S ribosomal protein S7, 30S ribosomal protein S8, 30S ribosomal protein S9, 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, 30S ribosomal protein S13, 30S ribosomal protein S14, 30S ribosomal protein S15, 30S ribosomal protein S16, 30S ribosomal protein S17, 30S ribosomal protein S18, 30S ribosomal protein S19, 30S ribosomal protein S20, 30S ribosomal protein S21, NpmA/RNA Complex
Authors:Dunkle, J.A., Conn, G.L., Dunham, C.M.
Deposit date:2014-02-04
Release date:2014-04-09
Last modified:2015-09-30
Method:X-RAY DIFFRACTION (3.8035 Å)
Cite:Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA.
Proc.Natl.Acad.Sci.USA, 111, 2014
4V7S
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CRYSTAL STRUCTURE OF THE E. COLI RIBOSOME BOUND TO TELITHROMYCIN.
Descriptor:Ribosome, telithromycin
Authors:Dunkle, J.A., Xiong, L., Mankin, A.S., Cate, J.H.D.
Deposit date:2010-08-05
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.2547 Å)
Cite:Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action.
Proc.Natl.Acad.Sci.USA, 107, 2010
4V7T
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CRYSTAL STRUCTURE OF THE E. COLI RIBOSOME BOUND TO CHLORAMPHENICOL.
Descriptor:Ribosome, chloramphenicol
Authors:Dunkle, J.A., Xiong, L., Mankin, A.S., Cate, J.H.D.
Deposit date:2010-08-14
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.1942 Å)
Cite:Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action.
Proc.Natl.Acad.Sci.USA, 107, 2010
4V7U
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CRYSTAL STRUCTURE OF THE E. COLI RIBOSOME BOUND TO ERYTHROMYCIN.
Descriptor:Ribosome
Authors:Dunkle, J.A., Xiong, L., Mankin, A.S., Cate, J.H.D.
Deposit date:2010-08-15
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action.
Proc.Natl.Acad.Sci.USA, 107, 2010
4V7V
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CRYSTAL STRUCTURE OF THE E. COLI RIBOSOME BOUND TO CLINDAMYCIN.
Descriptor:Ribosome, clindamycin
Authors:Dunkle, J.A., Xiong, L., Mankin, A.S., Cate, J.H.D.
Deposit date:2010-08-16
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.2891 Å)
Cite:Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action.
Proc.Natl.Acad.Sci.USA, 107, 2010
4V9D
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STRUCTURES OF THE BACTERIAL RIBOSOME IN CLASSICAL AND HYBRID STATES OF TRNA BINDING
Descriptor:PROTEIN/RNA Complex
Authors:Dunkle, J.A., Wang, L., Feldman, M.B., Pulk, A., Chen, V.B., Kapral, G.J., Noeske, J., Richardson, J.S., Blanchard, S.C., Cate, J.H.D.
Deposit date:2012-07-31
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of the bacterial ribosome in classical and hybrid states of tRNA binding.
Science, 332, 2011
1VVJ
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CRYSTAL STRUCTURE OF FRAMESHIFT SUPPRESSOR TRNA SUFA6 BOUND TO CODON CCC-G ON THE RIBOSOME
Descriptor:PROTEIN/RNA Complex
Authors:Maehigashi, T., Dunkle, J.A., Dunham, C.M.
Deposit date:2013-05-24
Release date:2014-08-06
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.440001 Å)
Cite:Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Proc.Natl.Acad.Sci.USA, 111, 2014
4L47
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CRYSTAL STRUCTURE OF FRAMESHIFT SUPPRESSOR TRNA SUFA6 BOUND TO CODON CCC-U ON THE RIBOSOME
Descriptor:PROTEIN/RNA Complex
Authors:Maehigashi, T., Dunkle, J.A., Dunham, C.M.
Deposit date:2013-06-07
Release date:2014-08-06
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.220001 Å)
Cite:Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Proc.Natl.Acad.Sci.USA, 111, 2014
4L71
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CRYSTAL STRUCTURE OF FRAMESHIFT SUPPRESSOR TRNA SUFA6 BOUND TO CODON CCC-A ON THE RIBOSOME
Descriptor:PROTEIN/RNA Complex
Authors:Maehigashi, T., Dunkle, J.A., Dunham, C.M.
Deposit date:2013-06-13
Release date:2014-08-06
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (3.900001 Å)
Cite:Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Proc.Natl.Acad.Sci.USA, 111, 2014
4LEL
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CRYSTAL STRUCTURE OF FRAMESHIFT SUPPRESSOR TRNA SUFA6 BOUND TO CODON CCG-G ON THE RIBOSOME
Descriptor:PROTEIN/RNA Complex
Authors:Maehigashi, T., Dunkle, J.A., Dunham, C.M.
Deposit date:2013-06-25
Release date:2014-08-06
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Proc.Natl.Acad.Sci.USA, 111, 2014
4LFZ
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CRYSTAL STRUCTURE OF FRAMESHIFT SUPPRESSOR TRNA SUFA6 BOUND TO CODON CCC-U IN THE ABSENCE OF PAROMOMYCIN
Descriptor:PROTEIN/RNA Complex
Authors:Maehigashi, T., Dunkle, J.A., Dunham, C.M.
Deposit date:2013-06-27
Release date:2014-08-06
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.920001 Å)
Cite:Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Proc.Natl.Acad.Sci.USA, 111, 2014
4LNT
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CRYSTAL STRUCTURE OF TRNA PROLINE (CGG) BOUND TO CODON CCC-U ON THE RIBOSOME
Descriptor:PROTEIN/RNA Complex
Authors:Maehigashi, T., Dunkle, J.A., Dunham, C.M.
Deposit date:2013-07-12
Release date:2014-08-06
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Proc.Natl.Acad.Sci.USA, 111, 2014
4LSK
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CRYSTAL STRUCTURE OF TRNA PROLINE (CGG) BOUND TO CODON CCG-G ON THE RIBOSOME
Descriptor:PROTEIN/RNA Complex
Authors:Maehigashi, T., Dunkle, J.A., Dunham, C.M.
Deposit date:2013-07-22
Release date:2014-08-06
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.480006 Å)
Cite:Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Proc.Natl.Acad.Sci.USA, 111, 2014
4LT8
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CRYSTAL STRUCTURE OF TRNA PROLINE (CGG) BOUND TO CODON CCC-G ON THE RIBOSOME
Descriptor:PROTEIN/RNA Complex
Authors:Maehigashi, T., Dunkle, J.A., Dunham, C.M.
Deposit date:2013-07-23
Release date:2014-08-06
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.140002 Å)
Cite:Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Proc.Natl.Acad.Sci.USA, 111, 2014
4P70
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CRYSTAL STRUCTURE OF UNMODIFIED TRNA PROLINE (CGG) BOUND TO CODON CCG ON THE RIBOSOME
Descriptor:30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, 30S ribosomal protein S5, 30S ribosomal protein S6, 30S ribosomal protein S7, 30S ribosomal protein S8, 30S ribosomal protein S9, 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, 30S ribosomal protein S13, 30S ribosomal protein S14, 30S ribosomal protein S15, 30S ribosomal protein S16, 30S ribosomal protein S17, 30S ribosomal protein S18, 30S ribosomal protein S19, 30S ribosomal protein S20, 30S ribosomal protein S21, 50S ribosomal protein L2, 50S ribosomal protein L3, 50S ribosomal protein L4, 50S ribosomal protein L5, 50S ribosomal protein L6, 50S ribosomal protein L9, 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L15, 50S ribosomal protein L16, 50S ribosomal protein L17, 50S ribosomal protein L18, 50S ribosomal protein L19, 50S ribosomal protein L20, 50S ribosomal protein L21, 50S ribosomal protein L22, 50S ribosomal protein L23, 50S ribosomal protein L24, 50S ribosomal protein L25, 50S ribosomal protein L27, 50S ribosomal protein L28, 50S ribosomal protein L29, 50S ribosomal protein L30, 50S ribosomal protein L32, 50S ribosomal protein L33, 50S ribosomal protein L34, 50S ribosomal protein L35, 50S ribosomal protein L36/RNA Complex
Authors:Maehigashi, T., Dunkle, J.A., Dunham, C.M.
Deposit date:2014-03-25
Release date:2014-08-13
Last modified:2015-02-25
Method:X-RAY DIFFRACTION (3.68 Å)
Cite:Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Proc.Natl.Acad.Sci.USA, 111, 2014
4PX8
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STRUCTURE OF P. VULGARIS HIGB TOXIN
Descriptor:Killer protein
Authors:Schureck, M.A., Dunkle, J.A., Maehigashi, T., Dunham, C.M.
Deposit date:2014-03-22
Release date:2015-10-21
Last modified:2015-11-25
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Defining the mRNA recognition signature of a bacterial toxin protein.
Proc.Natl.Acad.Sci.USA, 112, 2015
4V6C
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CRYSTAL STRUCTURE OF THE E. COLI 70S RIBOSOME IN AN INTERMEDIATE STATE OF RATCHETING
Descriptor:PROTEIN/RNA Complex
Authors:Zhang, W., Dunkle, J.A., Cate, J.H.D.
Deposit date:2009-06-27
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Structures of the ribosome in intermediate States of ratcheting.
Science, 325, 2009
4V6D
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CRYSTAL STRUCTURE OF THE E. COLI 70S RIBOSOME IN AN INTERMEDIATE STATE OF RATCHETING
Descriptor:PROTEIN/RNA Complex
Authors:Zhang, W., Dunkle, J.A., Cate, J.H.D.
Deposit date:2009-06-27
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.814 Å)
Cite:Structures of the ribosome in intermediate States of ratcheting.
Science, 325, 2009
4V6E
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CRYSTAL STRUCTURE OF THE E. COLI 70S RIBOSOME IN AN INTERMEDIATE STATE OF RATCHETING
Descriptor:PROTEIN/RNA Complex
Authors:Zhang, W., Dunkle, J.A., Cate, J.H.D.
Deposit date:2009-06-28
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.712 Å)
Cite:Structures of the ribosome in intermediate States of ratcheting.
Science, 325, 2009
4V8J
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CRYSTAL STRUCTURE OF THE BACTERIAL RIBOSOME RAM MUTATION G347U.
Descriptor:PROTEIN/RNA Complex
Authors:Fagan, C.E., Dunkle, J.A., Maehigashi, T., Dunham, C.M.
Deposit date:2011-12-20
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Reorganization of an intersubunit bridge induced by disparate 16S ribosomal ambiguity mutations mimics an EF-Tu-bound state.
Proc.Natl.Acad.Sci.USA, 110, 2013
4V97
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CRYSTAL STRUCTURE OF THE BACTERIAL RIBOSOME RAM MUTATION G299A.
Descriptor:PROTEIN/RNA Complex
Authors:Fagan, C.E., Dunkle, J.A., Maehigashi, T., Dunham, C.M.
Deposit date:2012-04-06
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.516 Å)
Cite:Reorganization of an intersubunit bridge induced by disparate 16S ribosomal ambiguity mutations mimics an EF-Tu-bound state.
Proc.Natl.Acad.Sci.USA, 110, 2013
4W4G
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POSTCLEAVAGE STATE OF 70S BOUND TO HIGB TOXIN AND AAA (LYSINE) CODON
Descriptor:30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, 30S ribosomal protein S5, 30S ribosomal protein S6, 30S ribosomal protein S7, 30S ribosomal protein S8, 30S ribosomal protein S9, 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, 30S ribosomal protein S13, 30S ribosomal protein S14 type Z, 30S ribosomal protein S15, 30S ribosomal protein S16, 30S ribosomal protein S17, 30S ribosomal protein S18, 30S ribosomal protein S19, 30S ribosomal protein S20, 30S ribosomal protein Thx, Host inhibition of growth B, 50S ribosomal protein L2, 50S ribosomal protein L3, 50S ribosomal protein L4, 50S ribosomal protein L5, 50S ribosomal protein L6, 50S ribosomal protein L9, 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L15, 50S ribosomal protein L16, 50S ribosomal protein L17, 50S ribosomal protein L18, 50S ribosomal protein L19, 50S ribosomal protein L20, 50S ribosomal protein L21, 50S ribosomal protein L22, 50S ribosomal protein L23, 50S ribosomal protein L24, 50S ribosomal protein L25, 50S ribosomal protein L27, 50S ribosomal protein L28, 50S ribosomal protein L29, 50S ribosomal protein L30, 50S ribosomal protein L31, 50S ribosomal protein L32, 50S ribosomal protein L33, 50S ribosomal protein L34, 50S ribosomal protein L35, 50S ribosomal protein L36/RNA Complex
Authors:Schureck, M.A., Maehigashi, T., Dunkle, J.A., Dunham, C.M.
Deposit date:2014-08-14
Release date:2015-10-21
Last modified:2015-11-25
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Defining the mRNA recognition signature of a bacterial toxin protein.
Proc.Natl.Acad.Sci.USA, 112, 2015
4YPB
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PRECLEAVAGE 70S STRUCTURE OF THE P. VULGARIS HIGB DELTAH92 TOXIN BOUND TO THE AAA CODON
Descriptor:Ribosome
Authors:Schureck, M.A., Dunkle, J.A., Maehigashi, T., Dunham, C.M.
Deposit date:2015-03-12
Release date:2015-10-21
Last modified:2015-11-25
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Defining the mRNA recognition signature of a bacterial toxin protein.
Proc.Natl.Acad.Sci.USA, 112, 2015
4YZV
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PRECLEAVAGE 70S STRUCTURE OF THE P. VULGARIS HIGB DELTAH92 TOXIN BOUND TO THE ACA CODON
Descriptor:Ribosome
Authors:Schureck, M.A., Dunkle, J.A., Maehigashi, T., Dunham, C.M.
Deposit date:2015-03-25
Release date:2015-10-21
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Defining the mRNA recognition signature of a bacterial toxin protein.
Proc.Natl.Acad.Sci.USA, 112, 2015
4WWW
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CRYSTAL STRUCTURE OF THE E. COLI RIBOSOME BOUND TO CEM-101
Descriptor:50S RIBOSOMAL PROTEIN L2, 50S RIBOSOMAL PROTEIN L3, 50S RIBOSOMAL PROTEIN L4, 50S RIBOSOMAL PROTEIN L5, 50S RIBOSOMAL PROTEIN L6, 50S RIBOSOMAL PROTEIN L9, 50S RIBOSOMAL PROTEIN L11, 50S RIBOSOMAL PROTEIN L13, 50S RIBOSOMAL PROTEIN L14, 50S RIBOSOMAL PROTEIN L15, 50S RIBOSOMAL PROTEIN L16, 50S RIBOSOMAL PROTEIN L17, 50S RIBOSOMAL PROTEIN L18, 50S RIBOSOMAL PROTEIN L19, 50S RIBOSOMAL PROTEIN L20, 50S RIBOSOMAL PROTEIN L21, 50S RIBOSOMAL PROTEIN L22, 50S RIBOSOMAL PROTEIN L23, 50S RIBOSOMAL PROTEIN L24, 50S RIBOSOMAL PROTEIN L25, 50S RIBOSOMAL PROTEIN L27, 50S RIBOSOMAL PROTEIN L28, 50S RIBOSOMAL PROTEIN L29, 50S RIBOSOMAL PROTEIN L30, 50S RIBOSOMAL PROTEIN L32, 50S RIBOSOMAL PROTEIN L33, 50S RIBOSOMAL PROTEIN L34, 50S RIBOSOMAL PROTEIN L35, 50S RIBOSOMAL PROTEIN L36, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, 30S RIBOSOMAL PROTEIN S4, 30S RIBOSOMAL PROTEIN S5, 30S RIBOSOMAL PROTEIN S6, 30S RIBOSOMAL PROTEIN S7, 30S RIBOSOMAL PROTEIN S8, 30S RIBOSOMAL PROTEIN S9, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, 30S RIBOSOMAL PROTEIN 12, 30S RIBOSOMAL PROTEIN S13, 30S RIBOSOMAL PROTEIN 14, 30S RIBOSOMAL PROTEIN S15, 30S RIBOSOMAL PROTEIN S16, 30S RIBOSOMAL PROTEIN S17, 30S RIBOSOMAL PROTEIN S18, 30S RIBOSOMAL PROTEIN S19, 30S RIBOSOMAL PROTEIN S20, 30S RIBOSOMAL PROTEIN S21/RNA Complex
Authors:Dunkle, J.A., Zhang, W., Cate, J.H.D., Mankin, A.S.
Deposit date:2014-11-12
Release date:2014-12-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Binding and action of CEM-101, a new fluoroketolide antibiotic that inhibits protein synthesis.
Antimicrob. Agents Chemother., 54, 2010
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