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1SQ0
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CRYSTAL STRUCTURE OF THE COMPLEX OF THE WILD-TYPE VON WILLEBRAND FACTOR A1 DOMAIN AND GLYCOPROTEIN IB ALPHA AT 2.6 ANGSTROM RESOLUTION
Descriptor:Von Willebrand factor (vWF) [Contains: Von Willebrand antigen II], Platelet glycoprotein Ib alpha chain (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (CD42B-alpha) (CD42B) [Contains: Glycocalicin]
Authors:Dumas, J.J., Kumar, R., McDonagh, T., Sullivan, F., Stahl, M.L., Somers, W.S., Mosyak, L.
Deposit date:2004-03-17
Release date:2004-04-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the wild-type von Willebrand factor A1-glycoprotein Ibalpha complex reveals conformation differences with a complex bearing von Willebrand disease mutations
J.Biol.Chem., 279, 2004
1JOC
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EEA1 HOMODIMER OF C-TERMINAL FYVE DOMAIN BOUND TO INOSITOL 1,3-DIPHOSPHATE
Descriptor:Early Endosomal Autoantigen 1, ZINC ION, PHOSPHORIC ACID MONO-(2,3,4,6-TETRAHYDROXY-5-PHOSPHONOOXY-CYCLOHEXYL) ESTER
Authors:Dumas, J.J., Merithew, E., Rajamani, D., Hayes, S., Lawe, D., Corvera, S., Lambright, D.G.
Deposit date:2001-07-27
Release date:2001-12-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Multivalent endosome targeting by homodimeric EEA1.
Mol.Cell, 8, 2001
1P8V
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CRYSTAL STRUCTURE OF THE COMPLEX OF PLATELET RECEPTOR GPIB-ALPHA AND ALPHA-THROMBIN AT 2.6A
Descriptor:Platelet glycoprotein Ib alpha chain, Prothrombin, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Dumas, J.J., Kumar, R., Seehra, J., Somers, W.S., Mosyak, L.
Deposit date:2003-05-07
Release date:2003-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the GpIbalpha-Thrombin Complex Essential for Platelet Aggregation
Science, 301, 2003
3RAB
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GPPNHP-BOUND RAB3A AT 2.0 A RESOLUTION
Descriptor:PROTEIN (RAB3A), MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Dumas, J.J., Zhu, Z., Connolly, J.L., Lambright, D.G.
Deposit date:1998-11-16
Release date:1999-04-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of activation and GTP hydrolysis in Rab proteins.
Structure Fold.Des., 7, 1999
1HUQ
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1.8A CRYSTAL STRUCTURE OF THE MONOMERIC GTPASE RAB5C (MOUSE)
Descriptor:RAB5C, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Merithew, E., Hatherly, S., Dumas, J.J., Lawe, D.C., Heller-Harrison, R., Lambright, D.G.
Deposit date:2001-01-04
Release date:2001-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural plasticity of an invariant hydrophobic triad in the switch regions of Rab GTPases is a determinant of effector recognition.
J.Biol.Chem., 276, 2001
1HXR
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CRYSTAL STRUCTURE OF MSS4 AT 1.65 ANGSTROMS
Descriptor:GUANINE NUCLEOTIDE EXCHANGE FACTOR MSS4, ZINC ION
Authors:Zhu, Z., Dumas, J.J., Lietzke, S.E., Lambright, D.G.
Deposit date:2001-01-16
Release date:2001-02-14
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A helical turn motif in Mss4 is a critical determinant of Rab binding and nucleotide release.
Biochemistry, 40, 2001