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1Z93
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HUMAN CARBONIC ANHYDRASE III:STRUCTURAL AND KINETIC STUDY OF CATALYSIS AND PROTON TRANSFER.
Descriptor:Carbonic anhydrase III, ZINC ION
Authors:Duda, D.M., Tu, C., Fisher, S.Z., An, H., Yoshioka, C., Govindasamy, L., Laipis, P.J., Agbandje-McKenna, M., Silverman, D.N., McKenna, R.
Deposit date:2005-03-31
Release date:2005-08-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Human Carbonic Anhydrase III: Structural and Kinetic Study of Catalysis and Proton Transfer
Biochemistry, 44, 2005
1Z97
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HUMAN CARBONIC ANHYDRASE III: STRUCTURAL AND KINETIC STUDY OF CATALYSIS AND PROTON TRANSFER.
Descriptor:Carbonic anhydrase III, ZINC ION
Authors:Duda, D.M., Tu, C., Fisher, S.Z., An, H., Yoshioka, C., Govindasamy, L., Laipis, P.J., Agbandje-McKenna, M., Silverman, D.N., McKenna, R.
Deposit date:2005-03-31
Release date:2005-08-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Human Carbonic Anhydrase III: Structural and Kinetic Study of Catalysis and Proton Transfer
Biochemistry, 44, 2005
1ZFN
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STRUCTURAL ANALYSIS OF ESCHERICHIA COLI THIF
Descriptor:Adenylyltransferase thiF, ZINC ION, ADENOSINE-5'-TRIPHOSPHATE
Authors:Duda, D.M., Walden, H., Sfondouris, J., Schulman, B.A.
Deposit date:2005-04-20
Release date:2005-06-14
Last modified:2014-11-19
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural Analysis of Escherichia Coli ThiF.
J.Mol.Biol., 349, 2005
1ZKM
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STRUCTURAL ANALYSIS OF ESCHERICHIA COLI THIF
Descriptor:Adenylyltransferase thiF, ZINC ION
Authors:Duda, D.M., Walden, H., Sfondouris, J., Schulman, B.A.
Deposit date:2005-05-03
Release date:2005-06-14
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural Analysis of Escherichia Coli ThiF.
J.Mol.Biol., 349, 2005
2EKE
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STRUCTURE OF A SUMO-BINDING-MOTIF MIMIC BOUND TO SMT3P-UBC9P: CONSERVATION OF A NONCOVALENT UBIQUITIN-LIKE PROTEIN-E2 COMPLEX AS A PLATFORM FOR SELECTIVE INTERACTIONS WITHIN A SUMO PATHWAY
Descriptor:SUMO-conjugating enzyme UBC9, Ubiquitin-like protein SMT3
Authors:Duda, D.M., Schulman, B.A.
Deposit date:2007-03-23
Release date:2007-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a SUMO-binding-motif Mimic Bound to Smt3p-Ubc9p: Conservation of a Non-covalent Ubiquitin-like Protein-E2 Complex as a Platform for Selective Interactions within a SUMO Pathway
J.Mol.Biol., 369, 2007
3DPL
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STRUCTURAL INSIGHTS INTO NEDD8 ACTIVATION OF CULLIN-RING LIGASES: CONFORMATIONAL CONTROL OF CONJUGATION.
Descriptor:Cullin-5, RING-box protein 1, ZINC ION
Authors:Duda, D.M., Schulman, B.A.
Deposit date:2008-07-08
Release date:2008-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation.
Cell(Cambridge,Mass.), 134, 2008
3DQV
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STRUCTURAL INSIGHTS INTO NEDD8 ACTIVATION OF CULLIN-RING LIGASES: CONFORMATIONAL CONTROL OF CONJUGATION
Descriptor:NEDD8, Cullin-5, Rbx1, ...
Authors:Duda, D.M., Borg, L.A., Scott, D.C., Hunt, H.W., Hammel, M., Schulman, B.A.
Deposit date:2008-07-09
Release date:2008-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation.
Cell(Cambridge,Mass.), 134, 2008
4F52
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STRUCTURE OF A GLOMULIN-RBX1-CUL1 COMPLEX
Descriptor:Cullin-1, E3 ubiquitin-protein ligase RBX1, Glomulin, ...
Authors:Duda, D.M., Olszewski, J.L., Schulman, B.A.
Deposit date:2012-05-11
Release date:2012-09-19
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of a Glomulin-RBX1-CUL1 Complex: Inhibition of a RING E3 Ligase through Masking of Its E2-Binding Surface.
Mol.Cell, 47, 2012
4KBL
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STRUCTURE OF HHARI, A RING-IBR-RING UBIQUITIN LIGASE: AUTOINHIBITION OF AN ARIADNE-FAMILY E3 AND INSIGHTS INTO LIGATION MECHANISM
Descriptor:E3 ubiquitin-protein ligase ARIH1, ZINC ION
Authors:Duda, D.M., Olszewski, J.L., Schulman, B.A.
Deposit date:2013-04-23
Release date:2013-05-29
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of HHARI, a RING-IBR-RING Ubiquitin Ligase: Autoinhibition of an Ariadne-Family E3 and Insights into Ligation Mechanism.
Structure, 21, 2013
4KC9
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STRUCTURE OF HHARI, A RING-IBR-RING UBIQUITIN LIGASE: AUTOINHIBITION OF AN ARIADNE-FAMILY E3 AND INSIGHTS INTO LIGATION MECHANISM
Descriptor:E3 ubiquitin-protein ligase ARIH1, ZINC ION
Authors:Duda, D.M., Olszewski, J.L., Schulman, B.A.
Deposit date:2013-04-24
Release date:2013-05-29
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (3.603 Å)
Cite:Structure of HHARI, a RING-IBR-RING Ubiquitin Ligase: Autoinhibition of an Ariadne-Family E3 and Insights into Ligation Mechanism.
Structure, 21, 2013
2GJD
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DISTINCT FUNCTIONAL DOMAINS OF UBC9 DICTATE CELL SURVIVAL AND RESISTANCE TO GENOTOXIC STRESS
Descriptor:Ubiquitin-conjugating enzyme E2-18 kDa
Authors:van Waardenburg, R.C., Duda, D.M., Lancaster, C.S., Schulman, B.A., Bjornsti, M.A.
Deposit date:2006-03-30
Release date:2006-07-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Distinct functional domains of ubc9 dictate cell survival and resistance to genotoxic stress.
Mol.Cell.Biol., 26, 2006
3FN1
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E2-RING EXPANSION OF THE NEDD8 CASCADE CONFERS SPECIFICITY TO CULLIN MODIFICATION.
Descriptor:NEDD8-activating enzyme E1 catalytic subunit, NEDD8-conjugating enzyme UBE2F
Authors:Huang, D.T., Ayrault, O., Hunt, H.W., Taherbhoy, A.M., Duda, D.M., Scott, D.C., Borg, L.A., Neale, G., Murray, P.J., Roussel, M.F., Schulman, B.A.
Deposit date:2008-12-22
Release date:2009-03-17
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification
Mol.Cell, 33, 2009
3O2P
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A DUAL E3 MECHANISM FOR RUB1 LIGATION TO CDC53: DCN1(P)-CDC53(WHB)
Descriptor:Defective in cullin neddylation protein 1, Cell division control protein 53, GLYCEROL
Authors:Scott, D.C., Monda, J.K., Grace, C.R.R., Duda, D.M., Kriwacki, R.W., Kurz, T., Schulman, B.A.
Deposit date:2010-07-22
Release date:2010-09-15
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.233 Å)
Cite:A dual E3 mechanism for Rub1 ligation to Cdc53.
Mol.Cell, 39, 2010
3O2U
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S. CEREVISIAE UBC12
Descriptor:NEDD8-conjugating enzyme UBC12, GLYCEROL
Authors:Scott, D.C., Monda, J.K., Grace, C.R.R., Duda, D.M., Kriwacki, R.W., Kurz, T., Schulman, B.A.
Deposit date:2010-07-22
Release date:2010-09-15
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:A dual E3 mechanism for Rub1 ligation to Cdc53.
Mol.Cell, 39, 2010
3O6B
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A DUAL E3 MECHANISM FOR RUB1 LIGATION TO CDC53: DCN1(P)-CDC53(WHB) LOW RESOLUTION
Descriptor:Defective in cullin neddylation protein 1, Cell division control protein 53
Authors:Scott, D.C., Monda, J.K., Grace, C.R.R., Duda, D.M., Kriwacki, R.W., Kurz, T., Schulman, B.A.
Deposit date:2010-07-28
Release date:2010-09-15
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A dual E3 mechanism for Rub1 ligation to Cdc53.
Mol.Cell, 39, 2010
3RTR
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A RING E3-SUBSTRATE COMPLEX POISED FOR UBIQUITIN-LIKE PROTEIN TRANSFER: STRUCTURAL INSIGHTS INTO CULLIN-RING LIGASES
Descriptor:Cullin-1, E3 ubiquitin-protein ligase RBX1, ZINC ION
Authors:Calabrese, M.F., Scott, D.C., Duda, D.M., Grace, C.R., Kurinov, I., Kriwacki, R.W., Schulman, B.A.
Deposit date:2011-05-03
Release date:2011-07-20
Last modified:2011-08-24
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:A RING E3-substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases.
Nat.Struct.Mol.Biol., 18, 2011
4GSJ
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CRYSTAL STRUCTURE OF ATG7 NTD K14A F16A D18A MUTANT
Descriptor:Ubiquitin-like modifier-activating enzyme ATG7, CITRIC ACID, ISOPROPYL ALCOHOL
Authors:Kaiser, S.E., Mao, K., Taherbhoy, A.M., Yu, S., Olszewski, J.L., Duda, D.M., Kurinov, I., Deng, A., Fenn, T.D., Klionsky, D.J., Schulman, B.A.
Deposit date:2012-08-27
Release date:2012-11-14
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.695 Å)
Cite:Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7-Atg3 and Atg7-Atg10 structures.
Nat.Struct.Mol.Biol., 19, 2012
4GSK
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CRYSTAL STRUCTURE OF AN ATG7-ATG10 CROSSLINKED COMPLEX
Descriptor:Ubiquitin-like modifier-activating enzyme ATG7, Ubiquitin-like-conjugating enzyme ATG10, ZINC ION
Authors:Kaiser, S.E., Mao, K., Taherbhoy, A.M., Yu, S., Olszewski, J.L., Duda, D.M., Kurinov, I., Deng, A., Fenn, T.D., Klionsky, D.J., Schulman, B.A.
Deposit date:2012-08-27
Release date:2012-11-14
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7-Atg3 and Atg7-Atg10 structures.
Nat.Struct.Mol.Biol., 19, 2012
4GSL
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CRYSTAL STRUCTURE OF AN ATG7-ATG3 CROSSLINKED COMPLEX
Descriptor:Ubiquitin-like modifier-activating enzyme ATG7, Autophagy-related protein 3, ZINC ION
Authors:Kaiser, S.E., Mao, K., Taherbhoy, A.M., Yu, S., Olszewski, J.L., Duda, D.M., Kurinov, I., Deng, A., Fenn, T.D., Klionsky, D.J., Schulman, B.A.
Deposit date:2012-08-27
Release date:2012-11-14
Last modified:2012-12-19
Method:X-RAY DIFFRACTION (2.703 Å)
Cite:Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7-Atg3 and Atg7-Atg10 structures.
Nat.Struct.Mol.Biol., 19, 2012
1MOO
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SITE SPECIFIC MUTANT (H64A) OF HUMAN CARBONIC ANHYDRASE II AT HIGH RESOLUTION
Descriptor:Carbonic Anhydrase II, ZINC ION, MERCURY (II) ION, ...
Authors:Duda, D.M., Govindasamy, L., Agbandje-McKenna, M., Tu, C.K., Silverman, D.N., McKenna, R.
Deposit date:2002-09-09
Release date:2002-09-18
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:The refined atomic structure of carbonic anhydrase II at 1.05 A resolution: implications of chemical rescue of proton transfer.
Acta Crystallogr.,Sect.D, 59, 2003
1LZV
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SITE-SPECIFIC MUTANT (TYR7 REPLACED WITH HIS) OF HUMAN CARBONIC ANHYDRASE II
Descriptor:Carbonic Anhydrase II, ZINC ION
Authors:Tu, C.K., Qian, M., An, H., Wadhwa, N.R., Duda, D.M., Yoshioka, C., Pathak, Y., McKenna, R., Laipis, P.J., Silverman, D.N.
Deposit date:2002-06-11
Release date:2002-10-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Kinetic analysis of multiple proton shuttles in the active site of human carbonic anhydrase.
J.Biol.Chem., 277, 2002
3HQH
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STRUCTURES OF SPOP-SUBSTRATE COMPLEXES: INSIGHTS INTO MOLECULAR ARCHITECTURES OF BTB-CUL3 UBIQUITIN LIGASES: SPOPMATHX-MACROH2ASBCPEP1
Descriptor:Speckle-type POZ protein, MacroH2A, ZINC ION
Authors:Zhuang, M., Schulman, B.A.
Deposit date:2009-06-06
Release date:2009-10-20
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
3HQI
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STRUCTURES OF SPOP-SUBSTRATE COMPLEXES: INSIGHTS INTO MOLECULAR ARCHITECTURES OF BTB-CUL3 UBIQUITIN LIGASES: SPOPMATHX/BTB/3-BOX-PUCSBC1
Descriptor:Speckle-type POZ protein, PucSBC1
Authors:Zhuang, M., Schulman, B.A.
Deposit date:2009-06-07
Release date:2009-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
3HQL
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STRUCTURES OF SPOP-SUBSTRATE COMPLEXES: INSIGHTS INTO MOLECULAR ARCHITECTURES OF BTB-CUL3 UBIQUITIN LIGASES:SPOPMATHX-PUCSBC1_PEP2
Descriptor:Speckle-type POZ protein, Puckered, SULFATE ION
Authors:Zhuang, M., Schulman, B.A.
Deposit date:2009-06-07
Release date:2009-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
3HQM
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STRUCTURES OF SPOP-SUBSTRATE COMPLEXES: INSIGHTS INTO MOLECULAR ARCHITECTURES OF BTB-CUL3 UBIQUITIN LIGASES: SPOPMATHX-CISBC2
Descriptor:Speckle-type POZ protein, Protein cubitus interruptus, SULFATE ION
Authors:Zhuang, M., Schulman, B.A.
Deposit date:2009-06-07
Release date:2009-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
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