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6WGK
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BU of 6wgk by Molmil
Fab portion of dupilumab with Crystal Kappa design and intrachain disulfide
Descriptor: Dupilumab Fab heavy chain, Dupilumab Fab light chain
Authors:Druzina, Z, Atwell, S, Pustilnik, A, Antonysamy, S, Ho, C, Lieu, R, Hendle, J, Benach, J, Wang, J.
Deposit date:2020-04-05
Release date:2020-09-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing.
Plos One, 15, 2020
6WGL
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BU of 6wgl by Molmil
Dupilumab fab with Crystal Kappa design complexed with human IL-4 receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dupilumab Fab heavy chain, ...
Authors:Druzina, Z, Atwell, S, Pustilnik, A, Antonysamy, S, Ho, C, Lieu, R, Hendle, J, Benach, J, Wang, J.
Deposit date:2020-04-05
Release date:2020-09-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing.
Plos One, 15, 2020
6WGB
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BU of 6wgb by Molmil
Crystal structure of the fab portion of dupilumab
Descriptor: Dupilumab Fab heavy chain, Dupilumab Fab light chain
Authors:Druzina, Z, Atwell, S, Pustilnik, A, Antonysamy, S, Ho, C, Lieu, R, Hendle, J, Benach, J, Wang, J.
Deposit date:2020-04-05
Release date:2020-09-16
Last modified:2020-09-23
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing.
Plos One, 15, 2020
6WG8
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BU of 6wg8 by Molmil
Fab portion of dupilumab with Crystal Kappa design
Descriptor: Dupilumab Fab heavy chain, Dupilumab Fab light chain, GLYCEROL
Authors:Druzina, Z, Atwell, S, Pustilnik, A, Antonysamy, S, Ho, C, Lieu, R, Hendle, J, Benach, J, Wang, J.
Deposit date:2020-04-05
Release date:2020-09-16
Last modified:2020-09-23
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing.
Plos One, 15, 2020
6WGJ
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BU of 6wgj by Molmil
Fab portion of dupilumab with Crystal Kappa design and no interchain disulfide
Descriptor: Dupilumab Fab heavy chain, Dupilumab Fab light chain
Authors:Druzina, Z, Atwell, S, Pustilnik, A, Antonysamy, S, Ho, C, Lieu, R, Hendle, J, Benach, J, Wang, J.
Deposit date:2020-04-05
Release date:2020-09-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing.
Plos One, 15, 2020
5KN5
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BU of 5kn5 by Molmil
TGFalpha/Epiregulin complex with neutralizing antibody LY3016859
Descriptor: Epiregulin Antibody LY3016859 Fab Heavy Chain, Epiregulin Antibody LY3016859 Fab Light Chain, Protransforming growth factor alpha, ...
Authors:Atwell, S, Boyles, J.S, Clawson, D.K, Druzina, Z, Josef, G.H, Weichert, K, Witcher, D.R.
Deposit date:2016-06-27
Release date:2016-08-31
Last modified:2016-11-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of selectivity and neutralizing activity of a TGF alpha /epiregulin specific antibody.
Protein Sci., 25, 2016
4GQB
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BU of 4gqb by Molmil
Crystal Structure of the human PRMT5:MEP50 Complex
Descriptor: (2S,5S,6E)-2,5-diamino-6-[(3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxydihydrofuran-2(3H)-ylidene]hexanoic acid, Histone H4 peptide, Methylosome protein 50, ...
Authors:Antonysamy, S, Bonday, Z, Campbell, R, Doyle, B, Druzina, Z, Gheyi, T, Han, B, Jungheim, L.N, Qian, Y, Rauch, C, Russell, M, Sauder, J.M, Wasserman, S.R, Weichert, K, Willard, F.S, Zhang, A, Emtage, S.
Deposit date:2012-08-22
Release date:2012-10-17
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Crystal structure of the human PRMT5:MEP50 complex.
Proc.Natl.Acad.Sci.USA, 109, 2012
4MI5
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BU of 4mi5 by Molmil
Crystal structure of the EZH2 SET domain
Descriptor: Histone-lysine N-methyltransferase EZH2, SULFATE ION, ZINC ION
Authors:Antonysamy, S, Condon, B, Druzina, Z, Bonanno, J, Gheyi, T, Macewan, I, Zhang, A, Ashok, S, Russell, M, Luz, J.G.
Deposit date:2013-08-30
Release date:2014-01-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Context of Disease-Associated Mutations and Putative Mechanism of Autoinhibition Revealed by X-Ray Crystallographic Analysis of the EZH2-SET Domain.
Plos One, 8, 2013
6WZK
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BU of 6wzk by Molmil
LY3041658 Fab bound to CXCL3
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, C-X-C motif chemokine 3, ...
Authors:Durbin, J.D, Druzina, Z.
Deposit date:2020-05-14
Release date:2020-11-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody.
Mabs, 12
6WZL
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BU of 6wzl by Molmil
LY3041658 Fab bound to CXCL7
Descriptor: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, C-X-C motif chemokine 7, LY3041658 Fab heavy chain, ...
Authors:Durbin, J.D, Druzina, Z.
Deposit date:2020-05-14
Release date:2020-11-25
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody.
Mabs, 12
6WZM
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BU of 6wzm by Molmil
LY3041658 Fab bound to CXCL8
Descriptor: 1,2-ETHANEDIOL, Interleukin-8, LY3041658 Fab heavy chain, ...
Authors:Durbin, J.D, Druzina, Z.
Deposit date:2020-05-14
Release date:2020-11-25
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody.
Mabs, 12
6WZJ
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BU of 6wzj by Molmil
LY3041658 Fab bound to CXCL2
Descriptor: C-X-C motif chemokine 2, LY3041658 Fab Heavy Chain, LY3041658 Fab Light Chain
Authors:Durbin, J.D, Druzina, Z.
Deposit date:2020-05-14
Release date:2020-11-25
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody.
Mabs, 12
6WIO
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BU of 6wio by Molmil
Fab antigen complex
Descriptor: Fab Heavy chain, Fab Light chain, Interleukin-17A
Authors:Antonysamy, S.
Deposit date:2020-04-10
Release date:2020-09-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing.
Plos One, 15, 2020
6WIR
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BU of 6wir by Molmil
Fab antigen complex
Descriptor: Fab heavy chain, Fab light chain, Interleukin-17A
Authors:Antonysamy, S.
Deposit date:2020-04-10
Release date:2020-09-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing.
Plos One, 15, 2020
8T7I
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BU of 8t7i by Molmil
Structure of the S1CE variant of Fab F1 (FabS1CE-F1)
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, S1CE variant of Fab F1 heavy chain, ...
Authors:Singer, A.U, Bruce, H.A, Enderle, L, Blazer, L, Adams, J.J, Sicheri, F, Sidhu, S.S.
Deposit date:2023-06-20
Release date:2023-11-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci., 33, 2024
8T7G
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BU of 8t7g by Molmil
Structure of the CK variant of Fab F1 (FabC-F1)
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, CK variant of Fab F1 heavy chain, ...
Authors:Singer, A.U, Bruce, H.A, Blazer, L, Adams, J.J, Sicheri, F, Sidhu, S.S.
Deposit date:2023-06-20
Release date:2023-11-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci., 33, 2024
8T7F
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BU of 8t7f by Molmil
Structure of the S1 variant of Fab F1
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, S1 variant of Fab F1 heavy chain, S1 variant of Fab F1 light chain, ...
Authors:Singer, A.U, Bruce, H.A, Enderle, L, Blazer, L, Adams, J.J, Sicheri, F, Sidhu, S.S.
Deposit date:2023-06-20
Release date:2023-11-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci., 33, 2024

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PDB entries from 2024-03-27

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