Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1SYM
DownloadVisualize
BU of 1sym by Molmil
3-D SOLUTION STRUCTURE OF REDUCED APO-S100B FROM RAT, NMR, 20 STRUCTURES
Descriptor: S100B
Authors:Drohat, A.C, Weber, D.J.
Deposit date:1996-05-29
Release date:1996-12-07
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure of rat apo-S100B(beta beta) as determined by NMR spectroscopy.
Biochemistry, 35, 1996
1QLK
DownloadVisualize
BU of 1qlk by Molmil
SOLUTION STRUCTURE OF CA(2+)-LOADED RAT S100B (BETABETA) NMR, 20 STRUCTURES
Descriptor: CALCIUM ION, S-100 PROTEIN
Authors:Drohat, A.C, Baldisseri, D.M, Rustandi, R.R, Weber, D.J.
Deposit date:1997-09-26
Release date:1998-11-11
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure of calcium-bound rat S100B(betabeta) as determined by nuclear magnetic resonance spectroscopy,.
Biochemistry, 37, 1998
1LMZ
DownloadVisualize
BU of 1lmz by Molmil
Solution Structure of 3-Methyladenine DNA Glycosylase I (TAG)
Descriptor: 3-methyladenine DNA glycosylase I (TAG)
Authors:Drohat, A.C, Kwon, K, Krosky, D.J, Stivers, J.T.
Deposit date:2002-05-02
Release date:2002-08-28
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:3-Methyladenine DNA glycosylase I is an unexpected helix-hairpin-helix superfamily member.
Nat.Struct.Biol., 9, 2002
1B4C
DownloadVisualize
BU of 1b4c by Molmil
SOLUTION STRUCTURE OF RAT APO-S100B USING DIPOLAR COUPLINGS
Descriptor: PROTEIN (S-100 PROTEIN, BETA CHAIN)
Authors:Weber, D.J, Drohat, A.C, Tjandra, N, Baldisseri, D.M.
Deposit date:1998-12-17
Release date:1998-12-30
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:The use of dipolar couplings for determining the solution structure of rat apo-S100B(betabeta).
Protein Sci., 8, 1999
4EUG
DownloadVisualize
BU of 4eug by Molmil
Crystallographic and Enzymatic Studies of an Active Site Variant H187Q of Escherichia Coli Uracil DNA Glycosylase: Crystal Structures of Mutant H187Q and its Uracil Complex
Descriptor: PROTEIN (GLYCOSYLASE)
Authors:Xiao, G, Tordova, M, Drohat, A.C, Jagadeesh, J, Stivers, J.T, Gilliland, G.L.
Deposit date:1998-12-27
Release date:1999-07-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Heteronuclear NMR and crystallographic studies of wild-type and H187Q Escherichia coli uracil DNA glycosylase: electrophilic catalysis of uracil expulsion by a neutral histidine 187.
Biochemistry, 38, 1999
2EUG
DownloadVisualize
BU of 2eug by Molmil
CRYSTAL STRUCTURE OF ESCHERICHIA COLI URACIL DNA GLYCOSYLASE AND ITS COMPLEXES WITH URACIL AND GLYCEROL: STRUCTURE AND GLYCOSYLASE MECHANISM REVISITED
Descriptor: PROTEIN (GLYCOSYLASE), URACIL
Authors:Xiao, G, Tordova, M, Jagadeesh, J, Drohat, A.C, Stivers, J.T, Gilliland, G.L.
Deposit date:1998-10-13
Release date:1999-10-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of Escherichia coli uracil DNA glycosylase and its complexes with uracil and glycerol: structure and glycosylase mechanism revisited.
Proteins, 35, 1999
5JXY
DownloadVisualize
BU of 5jxy by Molmil
Enzyme-substrate complex of TDG catalytic domain bound to a G/U analog
Descriptor: DNA (28-MER), G/T mismatch-specific thymine DNA glycosylase
Authors:Pidugu, L.S, Pozharski, E, Malik, S.S, Drohat, A.C.
Deposit date:2016-05-13
Release date:2016-09-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues.
Nucleic Acids Res., 44, 2016
5T2W
DownloadVisualize
BU of 5t2w by Molmil
Structure of thymine DNA glycosylase bound to substrate analog 2'-F-5-formyl-dC
Descriptor: DNA (27-MER), DNA (28-MER), G/T mismatch-specific thymine DNA glycosylase
Authors:Pidugu, L.S, Pozharski, E, Drohat, A.C.
Deposit date:2016-08-24
Release date:2016-11-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis for Excision of 5-Formylcytosine by Thymine DNA Glycosylase.
Biochemistry, 55, 2016
2RBA
DownloadVisualize
BU of 2rba by Molmil
Structure of Human Thymine DNA Glycosylase Bound to Abasic and Undamaged DNA
Descriptor: DNA (5'-D(*DCP*DAP*DGP*DCP*DTP*DCP*DTP*DGP*DTP*DAP*DCP*DGP*DTP*DGP*DAP*DGP*DCP*DAP*DGP*DTP*DGP*DGP*DA)-3'), DNA (5'-D(*DCP*DCP*DAP*DCP*DTP*DGP*DCP*DTP*DCP*DAP*(3DR)P*DGP*DTP*DAP*DCP*DAP*DGP*DAP*DGP*DCP*DTP*DGP*DT)-3'), G/T mismatch-specific thymine DNA glycosylase
Authors:Maiti, A, Pozharski, E, Drohat, A.C.
Deposit date:2007-09-18
Release date:2008-06-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Crystal structure of human thymine DNA glycosylase bound to DNA elucidates sequence-specific mismatch recognition.
Proc.Natl.Acad.Sci.Usa, 105, 2008
4LND
DownloadVisualize
BU of 4lnd by Molmil
Crystal structure of human apurinic/apyrimidinic endonuclease 1 with essential Mg2+ cofactor
Descriptor: DNA-(apurinic or apyrimidinic site) lyase, MAGNESIUM ION
Authors:Manvilla, B.A, Pozharski, E, Toth, E.A, Drohat, A.C.
Deposit date:2013-07-11
Release date:2013-11-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structure of human apurinic/apyrimidinic endonuclease 1 with the essential Mg(2+) cofactor.
Acta Crystallogr.,Sect.D, 69, 2013
3UFJ
DownloadVisualize
BU of 3ufj by Molmil
Human Thymine DNA Glycosylase Bound to Substrate Analog 2'-fluoro-2'-deoxyuridine
Descriptor: 5'-D(*CP*AP*GP*CP*TP*CP*TP*GP*TP*AP*CP*GP*TP*GP*AP*GP*CP*AP*GP*TP*GP*GP*A)-3', 5'-D(*CP*CP*AP*CP*TP*GP*CP*TP*CP*AP*(UF2)P*GP*TP*AP*CP*AP*GP*AP*GP*CP*TP*GP*T)-3', G/T mismatch-specific thymine DNA glycosylase
Authors:Pozharski, E, Maiti, A, Drohat, A.C.
Deposit date:2011-11-01
Release date:2012-04-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.967 Å)
Cite:Lesion processing by a repair enzyme is severely curtailed by residues needed to prevent aberrant activity on undamaged DNA.
Proc.Natl.Acad.Sci.USA, 109, 2012
3EUG
DownloadVisualize
BU of 3eug by Molmil
CRYSTAL STRUCTURE OF ESCHERICHIA COLI URACIL DNA GLYCOSYLASE AND ITS COMPLEXES WITH URACIL AND GLYCEROL: STRUCTURE AND GLYCOSYLASE MECHANISM REVISITED
Descriptor: GLYCEROL, PROTEIN (GLYCOSYLASE)
Authors:Xiao, G, Tordova, M, Jagadeesh, J, Drohat, A.C, Stivers, J.T, Gilliland, G.L.
Deposit date:1998-10-13
Release date:1999-10-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Crystal structure of Escherichia coli uracil DNA glycosylase and its complexes with uracil and glycerol: structure and glycosylase mechanism revisited.
Proteins, 35, 1999
5HF7
DownloadVisualize
BU of 5hf7 by Molmil
TDG enzyme-substrate complex
Descriptor: DNA (28-MER), G/T mismatch-specific thymine DNA glycosylase
Authors:Pozharski, E, Malik, S.S, Drohat, A.C.
Deposit date:2016-01-06
Release date:2016-09-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues.
Nucleic Acids Res., 44, 2016
7TC3
DownloadVisualize
BU of 7tc3 by Molmil
Human APE1 in the apo form
Descriptor: 1,2-ETHANEDIOL, DNA-(apurinic or apyrimidinic site) endonuclease, mitochondrial
Authors:Pidugu, L.S, Pozharski, E, Drohat, A.C.
Deposit date:2021-12-22
Release date:2022-12-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.252 Å)
Cite:Characterizing inhibitors of human AP endonuclease 1.
Plos One, 18, 2023
7TC2
DownloadVisualize
BU of 7tc2 by Molmil
Human APE1 in complex with 5-nitroindole-2-carboxylic acid
Descriptor: 1,2-ETHANEDIOL, 5-nitro-1H-indole-2-carboxylic acid, DI(HYDROXYETHYL)ETHER, ...
Authors:Pidugu, L.S, Pozharski, E, Drohat, A.C.
Deposit date:2021-12-22
Release date:2022-12-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Characterizing inhibitors of human AP endonuclease 1.
Plos One, 18, 2023
1EUG
DownloadVisualize
BU of 1eug by Molmil
CRYSTAL STRUCTURE OF ESCHERICHIA COLI URACIL DNA GLYCOSYLASE AND ITS COMPLEXES WITH URACIL AND GLYCEROL: STRUCTURE AND GLYCOSYLASE MECHANISM REVISITED
Descriptor: PROTEIN (GLYCOSYLASE)
Authors:Xiao, G, Tordova, M, Jagadeesh, J, Drohat, A.C, Stivers, J.T, Gilliland, G.L.
Deposit date:1998-10-12
Release date:1999-10-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of Escherichia coli uracil DNA glycosylase and its complexes with uracil and glycerol: structure and glycosylase mechanism revisited.
Proteins, 35, 1999
4XEG
DownloadVisualize
BU of 4xeg by Molmil
Structure of the enzyme-product complex resulting from TDG action on a G/hmU mismatch
Descriptor: 1,2-ETHANEDIOL, ACETIC ACID, DNA (28-MER), ...
Authors:Pozharski, E, Malik, S.S, Drohat, A.C.
Deposit date:2014-12-23
Release date:2015-09-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA.
Nucleic Acids Res., 43, 2015
4Z47
DownloadVisualize
BU of 4z47 by Molmil
Structure of the enzyme-product complex resulting from TDG action on a GU mismatch in the presence of excess base
Descriptor: 1,2-ETHANEDIOL, ACETIC ACID, DNA, ...
Authors:Pozharski, E, Malik, S.S, Drohat, A.C.
Deposit date:2015-04-01
Release date:2015-09-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA.
Nucleic Acids Res., 43, 2015
4Z3A
DownloadVisualize
BU of 4z3a by Molmil
Acetate-free structure of the enzyme-product complex resulting from TDG action on a GU mismatch
Descriptor: DNA (28-MER), G/T mismatch-specific thymine DNA glycosylase
Authors:Pozharski, E, Malik, S.S, Drohat, A.C.
Deposit date:2015-03-31
Release date:2015-09-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA.
Nucleic Acids Res., 43, 2015
4Z7Z
DownloadVisualize
BU of 4z7z by Molmil
Structure of the enzyme-product complex resulting from TDG action on a GT mismatch in the presence of excess base
Descriptor: 1,2-ETHANEDIOL, ACETIC ACID, DNA (28-MER), ...
Authors:Pozharski, E, Malik, S.S, Drohat, A.C.
Deposit date:2015-04-08
Release date:2015-09-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA.
Nucleic Acids Res., 43, 2015
4Z7B
DownloadVisualize
BU of 4z7b by Molmil
Structure of the enzyme-product complex resulting from TDG action on a GfC mismatch
Descriptor: 1,2-ETHANEDIOL, ACETIC ACID, DNA (28-MER), ...
Authors:Pozharski, E, Malik, S.S, Drohat, A.C.
Deposit date:2015-04-07
Release date:2015-09-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA.
Nucleic Acids Res., 43, 2015
4DK9
DownloadVisualize
BU of 4dk9 by Molmil
Crystal Structure of MBD4 Catalytic Domain Bound to Abasic DNA
Descriptor: 5'-D(*AP*AP*GP*AP*CP*GP*TP*GP*GP*AP*C)-3', 5'-D(*TP*GP*TP*CP*CP*AP*(3DR)P*GP*TP*CP*T)-3', Methyl-CpG-binding domain protein 4, ...
Authors:Manvilla, B.A, Toth, E.A, Drohat, A.C.
Deposit date:2012-02-03
Release date:2012-04-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Crystal Structure of Human Methyl-Binding Domain IV Glycosylase Bound to Abasic DNA.
J.Mol.Biol., 420, 2012
5CYS
DownloadVisualize
BU of 5cys by Molmil
Structure of the enzyme-product complex resulting from TDG action on a GcaC mismatch
Descriptor: ACETIC ACID, DNA (28-MER), G/T mismatch-specific thymine DNA glycosylase
Authors:Pozharski, E, Malik, S.S, Drohat, A.C.
Deposit date:2015-07-30
Release date:2015-09-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Characterizing the enzyme-product complexes of thymine DNA glycosylase using crystallography and NMR
Nucleic Acids Res., 2015
5EUG
DownloadVisualize
BU of 5eug by Molmil
CRYSTALLOGRAPHIC AND ENZYMATIC STUDIES OF AN ACTIVE SITE VARIANT H187Q OF ESCHERICHIA COLI URACIL DNA GLYCOSYLASE: CRYSTAL STRUCTURES OF MUTANT H187Q AND ITS URACIL COMPLEX
Descriptor: PROTEIN (GLYCOSYLASE), URACIL
Authors:Xiao, G, Tordova, M, Drohat, A.C, Jagadeesh, J, Stivers, J.T, Gilliland, G.L.
Deposit date:1998-12-27
Release date:1999-07-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of Escherichia coli uracil DNA glycosylase and its complexes with uracil and glycerol: structure and glycosylase mechanism revisited.
Proteins, 35, 1999
5FF8
DownloadVisualize
BU of 5ff8 by Molmil
TDG enzyme-product complex
Descriptor: DNA, G/T mismatch-specific thymine DNA glycosylase
Authors:Pozharski, E, Malik, S.S, Drohat, A.C.
Deposit date:2015-12-18
Release date:2016-09-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues.
Nucleic Acids Res., 44, 2016

 

12>

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon