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6NHL
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CRYSTAL STRUCTURE OF QUEE FROM ESCHERICHIA COLI
分子名称:7-carboxy-7-deazaguanine synthase, FE (III) ION, IRON/SULFUR CLUSTER, ...
著者Grell, T.A.J., Bell, B.N., Nguyen, C., Dowling, D.P., Drennan, C.L.
登録日2018-12-23
公開日2019-01-16
最終更新日2019-02-06
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献Crystal structure of AdoMet radical enzyme 7-carboxy-7-deazaguanine synthase from Escherichia coli suggests how modifications near [4Fe-4S] cluster engender flavodoxin specificity.
Protein Sci., 28, 2019
6ND3
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WILD-TYPE CHOLINE TMA LYASE IN COMPLEX WITH BETAINE ALDEHYDE
分子名称:Choline trimethylamine-lyase, BETAINE ALDEHYDE
著者Funk, M.A., Drennan, C.L.
登録日2018-12-13
公開日2019-01-16
実験手法X-RAY DIFFRACTION (2.364 Å)
主引用文献Structure-Guided Identification of a Small Molecule That Inhibits Anaerobic Choline Metabolism by Human Gut Bacteria.
J. Am. Chem. Soc., 2018
6MSO
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CRYSTAL STRUCTURE OF MITOCHONDRIAL FUMARATE HYDRATASE FROM LEISHMANIA MAJOR IN A COMPLEX WITH INHIBITOR THIOMALATE
分子名称:fumarate hydratase, IRON/SULFUR CLUSTER, GLYCEROL, ...
著者Feliciano, P.R., Drennan, C.L., Nonato, M.C.
登録日2018-10-17
公開日2019-01-30
最終更新日2019-02-27
実験手法X-RAY DIFFRACTION (2.053 Å)
主引用文献Crystal Structures of Fumarate Hydratases from Leishmania major in a Complex with Inhibitor 2-Thiomalate.
ACS Chem. Biol., 14, 2019
6MSN
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CRYSTAL STRUCTURE OF CYTOSOLIC FUMARATE HYDRATASE FROM LEISHMANIA MAJOR IN A COMPLEX WITH INHIBITOR THIOMALATE
分子名称:fumarate hydratase, IRON/SULFUR CLUSTER, (2S)-2-sulfanylbutanedioic acid
著者Feliciano, P.R., Drennan, C.L., Nonato, M.C.
登録日2018-10-17
公開日2019-01-30
最終更新日2019-02-27
実験手法X-RAY DIFFRACTION (1.591 Å)
主引用文献Crystal Structures of Fumarate Hydratases from Leishmania major in a Complex with Inhibitor 2-Thiomalate.
ACS Chem. Biol., 14, 2019
6EFN
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STRUCTURE OF A RIPP MATURASE, SKFB
分子名称:Sporulation killing factor maturation protein SkfB, S-ADENOSYLMETHIONINE, IRON/SULFUR CLUSTER, ...
著者Grell, T.A.J., Drennan, C.L.
登録日2018-08-16
公開日2018-10-24
実験手法X-RAY DIFFRACTION (1.291 Å)
主引用文献Structure of a RiPP maturase, SkfB
J.Biol.Chem., 2018
6DS2
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CRYSTAL STRUCTURE OF NI(II)-BOUND HUMAN CALPROTECTIN
分子名称:Protein S100-A8, Protein S100-A9, SODIUM ION, ...
著者Nolan, E.M., Drennan, C.L., Nakashige, T.G.
登録日2018-06-13
公開日2018-07-04
最終更新日2018-08-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Biophysical Examination of the Calcium-Modulated Nickel-Binding Properties of Human Calprotectin Reveals Conformational Change in the EF-Hand Domains and His3Asp Site.
Biochemistry, 57, 2018
6DJT
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STRUCTURE OF TYW1 WITH A LYSINE-PYRUVATE ADDUCT BOUND
分子名称:S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, IRON/SULFUR CLUSTER, GLYCEROL, ...
著者Grell, T.A.J., Drennan, C.L.
登録日2018-05-26
公開日2018-06-13
最終更新日2018-06-20
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Biochemical and Structural Characterization of a Schiff Base in the Radical-Mediated Biosynthesis of 4-Demethylwyosine by TYW1.
J. Am. Chem. Soc., 140, 2018
6DCH
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STRUCTURE OF ISONITRILE BIOSYNTHESIS ENZYME SCOE
分子名称:ScoE protein, ACETATE ION, CHLORIDE ION, ...
著者Born, D.A., Drennan, C.L.
登録日2018-05-07
公開日2018-06-27
最終更新日2018-08-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Isonitrile Formation by a Non-Heme Iron(II)-Dependent Oxidase/Decarboxylase.
Angew. Chem. Int. Ed. Engl., 57, 2018
6DC2
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CRYSTAL STRUCTURE OF DESULFOVIBRIO VULGARIS CARBON MONOXIDE DEHYDROGENASE C301S VARIANT
分子名称:Carbon monoxide dehydrogenase, IRON/SULFUR CLUSTER, FE2/S2 (INORGANIC) CLUSTER, ...
著者Wittenborn, E.C., Drennan, C.L.
登録日2018-05-04
公開日2018-10-03
最終更新日2018-10-17
実験手法X-RAY DIFFRACTION (1.992 Å)
主引用文献Redox-dependent rearrangements of the NiFeS cluster of carbon monoxide dehydrogenase.
Elife, 7, 2018
6CIQ
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PYRUVATE:FERREDOXIN OXIDOREDUCTASE FROM MOORELLA THERMOACETICA WITH COENZYME A BOUND
分子名称:PYRUVATE-FERREDOXIN OXIDOREDUCTASE, IRON/SULFUR CLUSTER, THIAMINE DIPHOSPHATE, ...
著者Chen, P.Y.-T., Drennan, C.L.
登録日2018-02-24
公開日2018-03-28
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (3.302 Å)
主引用文献Binding site for coenzyme A revealed in the structure of pyruvate:ferredoxin oxidoreductase fromMoorella thermoacetica.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6CIP
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PYRUVATE:FERREDOXIN OXIDOREDUCTASE FROM MOORELLA THERMOACETICA WITH ACETYL-TPP BOUND
分子名称:PYRUVATE-FERREDOXIN OXIDOREDUCTASE, IRON/SULFUR CLUSTER, 2-ACETYL-THIAMINE DIPHOSPHATE, ...
著者Chen, P.Y.-T., Drennan, C.L.
登録日2018-02-24
公開日2018-03-28
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (3.189 Å)
主引用文献Binding site for coenzyme A revealed in the structure of pyruvate:ferredoxin oxidoreductase fromMoorella thermoacetica.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6CIO
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PYRUVATE:FERREDOXIN OXIDOREDUCTASE FROM MOORELLA THERMOACETICA WITH LACTYL-TPP BOUND
分子名称:PYRUVATE-FERREDOXIN OXIDOREDUCTASE, IRON/SULFUR CLUSTER, 3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-(1-CARBOXY-1-HYDROXYETHYL)-5-(2-{[HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM, ...
著者Chen, P.Y.-T., Drennan, C.L.
登録日2018-02-24
公開日2018-03-28
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (3.003 Å)
主引用文献Binding site for coenzyme A revealed in the structure of pyruvate:ferredoxin oxidoreductase fromMoorella thermoacetica.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6CIN
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CRYSTAL STRUCTURE OF PYRUVATE:FERREDOXIN OXIDOREDUCTASE FROM MOORELLA THERMOACETICA
分子名称:PYRUVATE-FERREDOXIN OXIDOREDUCTASE, IRON/SULFUR CLUSTER, THIAMINE DIPHOSPHATE, ...
著者Chen, P.Y.-T., Drennan, C.L.
登録日2018-02-24
公開日2018-03-28
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Binding site for coenzyme A revealed in the structure of pyruvate:ferredoxin oxidoreductase fromMoorella thermoacetica.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6B9T
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CRYSTAL STRUCTURE OF MPNS WITH SUBSTRATE 2-HYDROXYETHYLPHOSPHONATE (2-HEP) AND FE(II) BOUND
分子名称:Methylphosphonate synthase, FE (III) ION, (2-hydroxyethyl)phosphonic acid, ...
著者Born, D.A., Drennan, C.L.
登録日2017-10-11
公開日2017-12-20
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural basis for methylphosphonate biosynthesis.
Science, 358, 2017
6B9S
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MPNS CRYSTALLIZED IN THE ABSENCE OF SUBSTRATE
分子名称:Methylphosphonate synthase, FE (III) ION
著者Born, D.A., Drennan, C.L.
登録日2017-10-11
公開日2017-12-20
実験手法X-RAY DIFFRACTION (2.373 Å)
主引用文献Structural basis for methylphosphonate biosynthesis.
Science, 358, 2017
6B9R
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STREPTOMYCES ALBUS HEPD WITH SUBSTRATE 2-HYDROXYETHYLPHOSPHONATE (2-HEP) AND FE(II) BOUND
分子名称:Hydroxyethylphosphonate dioxygenase, FE (III) ION, (2-hydroxyethyl)phosphonic acid, ...
著者Born, D.A., Drennan, C.L.
登録日2017-10-11
公開日2017-12-20
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献Structural basis for methylphosphonate biosynthesis.
Science, 358, 2017
6B6Y
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CRYSTAL STRUCTURE OF DESULFOVIBRIO VULGARIS CARBON MONOXIDE DEHYDROGENASE, DITHIONITE-REDUCED THEN OXYGEN-EXPOSED (PROTEIN BATCH 2), OXIDIZED C-CLUSTER
分子名称:Carbon monoxide dehydrogenase, IRON/SULFUR CLUSTER, Fe(4)-Ni(1)-S(4) cluster, ...
著者Wittenborn, E.C., Drennan, C.L.
登録日2017-10-03
公開日2018-10-03
最終更新日2018-10-17
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Redox-dependent rearrangements of the NiFeS cluster of carbon monoxide dehydrogenase.
Elife, 7, 2018
6B6X
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CRYSTAL STRUCTURE OF DESULFOVIBRIO VULGARIS CARBON MONOXIDE DEHYDROGENASE, DITHIONITE-REDUCED (PROTEIN BATCH 2), CANONICAL C-CLUSTER
分子名称:Carbon monoxide dehydrogenase, IRON/SULFUR CLUSTER, FE(4)-NI(1)-S(4) CLUSTER, ...
著者Wittenborn, E.C., Drennan, C.L.
登録日2017-10-03
公開日2018-10-03
最終更新日2018-10-17
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Redox-dependent rearrangements of the NiFeS cluster of carbon monoxide dehydrogenase.
Elife, 7, 2018
6B6W
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CRYSTAL STRUCTURE OF DESULFOVIBRIO VULGARIS CARBON MONOXIDE DEHYDROGENASE, AS-ISOLATED (PROTEIN BATCH 2), OXIDIZED C-CLUSTER
分子名称:Carbon monoxide dehydrogenase, IRON/SULFUR CLUSTER, MAGNESIUM ION, ...
著者Wittenborn, E.C., Drennan, C.L.
登録日2017-10-03
公開日2018-10-03
最終更新日2018-10-17
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Redox-dependent rearrangements of the NiFeS cluster of carbon monoxide dehydrogenase.
Elife, 7, 2018
6B6V
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CRYSTAL STRUCTURE OF DESULFOVIBRIO VULGARIS CARBON MONOXIDE DEHYDROGENASE, AS-ISOLATED (PROTEIN BATCH 1), CANONICAL C-CLUSTER
分子名称:Carbon monoxide dehydrogenase, IRON/SULFUR CLUSTER, FE(4)-NI(1)-S(4) CLUSTER, ...
著者Wittenborn, E.C., Drennan, C.L.
登録日2017-10-03
公開日2018-10-03
最終更新日2018-10-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Redox-dependent rearrangements of the NiFeS cluster of carbon monoxide dehydrogenase.
Elife, 7, 2018
6AUI
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HUMAN RIBONUCLEOTIDE REDUCTASE LARGE SUBUNIT (ALPHA) WITH DATP AND CDP
分子名称:Ribonucleoside-diphosphate reductase large subunit, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Brignole, E.J., Drennan, C.L., Asturias, F.J., Tsai, K.L., Penczek, P.A.
登録日2017-09-01
公開日2018-04-18
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献3.3- angstrom resolution cryo-EM structure of human ribonucleotide reductase with substrate and allosteric regulators bound.
Elife, 7, 2018
5W1F
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CRYSTAL STRUCTURE OF NI(II)- AND CA(II)-BOUND HUMAN CALPROTECTIN
分子名称:Protein S100-A8, Protein S100-A9, SODIUM ION, ...
著者Nakashige, T.G., Drennan, C.L., Nolan, E.M.
登録日2017-06-03
公開日2017-06-14
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Nickel Sequestration by the Host-Defense Protein Human Calprotectin.
J. Am. Chem. Soc., 139, 2017
5USR
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CRYSTAL STRUCTURE OF HUMAN NFS1-ISD11 IN COMPLEX WITH E. COLI ACYL-CARRIER PROTEIN AT 3.09 ANGSTROMS
分子名称:Cysteine desulfurase, mitochondrial, LYR motif-containing protein 4, ...
著者Cory, S.A., Barondeau, D.P.
登録日2017-02-13
公開日2017-06-21
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Structure of human Fe-S assembly subcomplex reveals unexpected cysteine desulfurase architecture and acyl-ACP-ISD11 interactions.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UL4
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STRUCTURE OF COBALAMIN-DEPENDENT S-ADENOSYLMETHIONINE RADICAL ENZYME OXSB WITH AQUA-COBALAMIN AND S-ADENOSYLMETHIONINE BOUND
分子名称:OxsB protein, IRON/SULFUR CLUSTER, COBALAMIN, ...
著者Bridwell-Rabb, J., Drennan, C.L.
登録日2017-01-24
公開日2017-04-19
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A B12-dependent radical SAM enzyme involved in oxetanocin A biosynthesis.
Nature, 544, 2017
5UL3
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STRUCTURE OF COBALAMIN-DEPENDENT S-ADENOSYLMETHIONINE RADICAL ENZYME OXSB WITH AQUA-COBALAMIN BOUND
分子名称:OxsB protein, IRON/SULFUR CLUSTER, COBALAMIN, ...
著者Bridwell-Rabb, J., Drennan, C.L.
登録日2017-01-24
公開日2017-04-19
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A B12-dependent radical SAM enzyme involved in oxetanocin A biosynthesis.
Nature, 544, 2017