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Crystal structure of the phosphoinositol (3,4)-bisphosphate binding PH domain of TAPP1 from human.
Descriptor:	CITRIC ACID, TANDEM PH DOMAIN CONTAINING PROTEIN-1
Authors:	Thomas, C.C, Dowler, S, Deak, M, Alessi, D.R, Van Aalten, D.M.F.
Deposit date:	2001-07-17
Release date:	2002-07-11
Last modified:	2023-12-13
Method:	X-RAY DIFFRACTION (1.4 Å)
Cite:	Crystal Structure of the Phosphatidylinositol 3,4-Bisphosphate-Binding Pleckstrin Homology (Ph) Domain of Tandem Ph-Domain-Containing Protein 1 (Tapp1): Molecular Basis of Lipid Specificity Biochem.J., 358, 2001

Optimization of potent and selective ATM inhibitors suitable for a proof-of-concept study in Huntington's disease models
Descriptor:	2-morpholin-4-yl-6-[7-[(2~{R})-1-morpholin-4-ylpropan-2-yl]oxy-9~{H}-thioxanthen-4-yl]pyran-4-one, Phosphatidylinositol 3-kinase catalytic subunit type 3
Authors:	Leonard, P.M.
Deposit date:	2018-11-07
Release date:	2019-03-20
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (2.09 Å)
Cite:	Optimization of Potent and Selective Ataxia Telangiectasia-Mutated Inhibitors Suitable for a Proof-of-Concept Study in Huntington's Disease Models. J.Med.Chem., 62, 2019