Author results

3GB8
  • Download 3gb8
  • View 3gb8
Molmil generated image of 3gb8
CRYSTAL STRUCTURE OF CRM1/SNURPORTIN-1 COMPLEX
分子名称:Exportin-1, Snurportin-1
著者Dong, X., Biswas, A., Suel, K.E., Jackson, L.K., Martinez, R., Gu, H., Chook, Y.M.
登録日2009-02-19
公開日2009-03-31
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for leucine-rich nuclear export signal recognition by CRM1.
Nature, 458, 2009
1Z9M
  • Download 1z9m
  • View 1z9m
Molmil generated image of 1z9m
CRYSTAL STRUCTURE OF NECTIN-LIKE MOLECULE-1 PROTEIN DOMAIN 1
分子名称:GAPA225
著者Dong, X., Xu, F., Gong, Y., Gao, J., Lin, P., Chen, T., Peng, Y., Qiang, B., Yuan, J., Peng, X., Rao, Z.
登録日2005-04-03
公開日2006-02-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of the V Domain of Human Nectin-like Molecule-1/Syncam3/Tsll1/Igsf4b, a Neural Tissue-specific Immunoglobulin-like Cell-Cell Adhesion Molecule
J.Biol.Chem., 281, 2006
1WQL
  • Download 1wql
  • View 1wql
Molmil generated image of 1wql
CUMENE DIOXYGENASE (CUMA1A2) FROM PSEUDOMONAS FLUORESCENS IP01
分子名称:iron-sulfur protein large subunit of cumene dioxygenase, ethylbenzene dioxygenase small subunit, FE (II) ION, ...
著者Dong, X., Fushinobu, S., Fukuda, E., Terada, T., Nakamura, S., Shimizu, K., Nojiri, H., Omori, T., Shoun, H., Wakagi, T.
登録日2004-09-30
公開日2005-03-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of the Terminal Oxygenase Component of Cumene Dioxygenase from Pseudomonas fluorescens IP01
J.BACTERIOL., 187, 2005
1VS3
  • Download 1vs3
  • View 1vs3
Molmil generated image of 1vs3
CRYSTAL STRUCTURE OF THE TRNA PSEUDOURIDINE SYNTHASE TRUA FROM THERMUS THERMOPHILUS HB8
分子名称:tRNA pseudouridine synthase A
著者Dong, X., Bessho, Y., Shirouzu, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-06-28
公開日2006-12-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal Structure of tRNA Pseudouridine Synthase TruA from Thermus thermophilus HB8
Rna Biol., 3, 2006
2DUD
  • Download 2dud
  • View 2dud
Molmil generated image of 2dud
CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL SINGLE-STRANDED DNA-BINDING PROTEIN(HMTSSB)
分子名称:Single-stranded DNA-binding protein
著者Dong, X., Bessho, Y., Shirouzu, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-07-21
公開日2007-01-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of human mitochondrial single-stranded DNA-binding protein(hmtSSB)
To be Published
2EGV
  • Download 2egv
  • View 2egv
Molmil generated image of 2egv
CRYSTAL STRUCTURE OF RRNA METHYLTRANSFERASE WITH SAM LIGAND
分子名称:UPF0088 protein aq_165, S-ADENOSYLMETHIONINE
著者Dong, X., Shirouzu, M., Bessho, Y., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-02
公開日2007-09-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal structure of rRNA methyltransferase with SAM ligand
To be Published
2EGW
  • Download 2egw
  • View 2egw
Molmil generated image of 2egw
CRYSTAL STRUCTURE OF RRNA METHYLTRANSFERASE WITH SAH LIGAND
分子名称:UPF0088 protein aq_165, S-ADENOSYL-L-HOMOCYSTEINE
著者Dong, X., Shirouzu, M., Bessho, Y., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-02
公開日2007-09-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of rRNA methyltransferase with SAH ligand
To be Published
2MVU
  • Download 2mvu
  • View 2mvu
Molmil generated image of 2mvu
SOLUTION STRUCTURE OF THE 3,7-DIOXO-OCTYL ACTINORHODIN ACYL CARRIER PROTEIN FROM STREPTOMYCES COELICOLOR
分子名称:Actinorhodin polyketide synthase acyl carrier protein, N~3~-{(2S)-4-[(dihydroxyphosphanyl)oxy]-2-hydroxy-3,3-dimethylbutanoyl}-N-{2-[(3,7-dioxooctyl)sulfanyl]ethyl}-beta-alaninamide
著者Dong, X., Bailey, C., Williams, C., Crosby, J., Simpson, T.J., Willis, C.L., Crump, M.P.
登録日2014-10-15
公開日2015-10-21
実験手法SOLUTION NMR
主引用文献ACP-ligand recognition: Selection of derivatized aromatic biosynthetic intermediates
To be Published
2MVV
  • Download 2mvv
  • View 2mvv
Molmil generated image of 2mvv
SOLUTION STRUCTURE OF THE 5-PHENYL-3-OXO-PENTYL ACTINORHODIN ACYL CARRIER PROTEIN FROM STREPTOMYCES COELICOLOR
分子名称:Actinorhodin polyketide synthase acyl carrier protein, N~3~-{(2S)-4-[(dihydroxyphosphanyl)oxy]-2-hydroxy-3,3-dimethylbutanoyl}-N-{2-[(3-oxo-5-phenylpentyl)sulfanyl]ethyl}-beta-alaninamide
著者Dong, X., Bailey, C., Williams, C., Crosby, J., Simpson, T.J., Willis, C.L., Crump, M.P.
登録日2014-10-15
公開日2015-10-21
実験手法SOLUTION NMR
主引用文献ACP-ligand recognition: Selection of derivatized aromatic biosynthetic intermediates
To be Published
4G1E
  • Download 4g1e
  • View 4g1e
Molmil generated image of 4g1e
CRYSTAL STRUCTURE OF INTEGRIN ALPHA V BETA 3 WITH COIL-COILED TAG.
分子名称:Integrin alpha-V, Integrin beta-3, CALCIUM ION, ...
著者Dong, X., Mi, L., Zhu, J., Wang, W., Luo, B., Springer, T.A.
登録日2012-07-10
公開日2012-12-05
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献AlphaV Beta3 Integrin Crystal Structures and their Functional Implications
Biochemistry, 51, 2012
4UM8
  • Download 4um8
  • View 4um8
Molmil generated image of 4um8
CRYSTAL STRUCTURE OF ALPHA V BETA 6
分子名称:INTEGRIN ALPHA-V, INTEGRIN BETA-6, CHLORIDE ION, ...
著者Dong, X., Springer, T.A.
登録日2014-05-15
公開日2014-11-12
最終更新日2014-12-17
実験手法X-RAY DIFFRACTION (2.852 Å)
主引用文献Structural Determinants of Integrin Beta-Subunit Specificity for Latent Tgf-Beta
Nat.Struct.Mol.Biol., 21, 2014
4UM9
  • Download 4um9
  • View 4um9
Molmil generated image of 4um9
CRYSTAL STRUCTURE OF ALPHA V BETA 6 WITH PEPTIDE
分子名称:INTEGRIN ALPHA-V, INTEGRIN BETA-6, TRANSFORMING GROWTH FACTOR BETA 3, ...
著者Dong, X., Springer, T.A.
登録日2014-05-15
公開日2014-11-12
最終更新日2016-03-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Determinants of Integrin Beta-Subunit Specificity for Latent Tgf-Beta
Nat.Struct.Mol.Biol., 21, 2014
5FFG
  • Download 5ffg
  • View 5ffg
Molmil generated image of 5ffg
CRYSTAL STRUCTURE OF INTEGRIN ALPHA V BETA 6 HEAD
分子名称:Integrin alpha-V, Integrin beta-6, CALCIUM ION, ...
著者Dong, X., Springer, T.A.
登録日2015-12-18
公開日2017-01-25
最終更新日2017-02-15
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Force interacts with macromolecular structure in activation of TGF-beta.
Nature, 542, 2017
5FFO
  • Download 5ffo
  • View 5ffo
Molmil generated image of 5ffo
INTEGRIN ALPHA V BETA 6 IN COMPLEX WITH PRO-TGF-BETA
分子名称:Integrin alpha-V, Integrin beta-6, Transforming growth factor beta-1, ...
著者Dong, X., Zhao, B., Springer, T.A.
登録日2015-12-18
公開日2017-01-25
最終更新日2017-02-15
実験手法X-RAY DIFFRACTION (3.49 Å)
主引用文献Force interacts with macromolecular structure in activation of TGF-beta.
Nature, 542, 2017
5XK4
  • Download 5xk4
  • View 5xk4
Molmil generated image of 5xk4
RETRACTED STATE OF S65-PHOSPHORYLATED UBIQUITIN
分子名称:Polyubiquitin-B
著者Dong, X., Gong, Z., Qin, L.Y., Ran, M.L., Zhang, C.L., Liu, K., Liu, Z., Zhang, W.P., Tang, C.
登録日2017-05-05
公開日2017-06-28
最終更新日2017-07-12
実験手法SOLUTION NMR
主引用文献Ubiquitin S65 phosphorylation engenders a pH-sensitive conformational switch
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5Z2S
  • Download 5z2s
  • View 5z2s
Molmil generated image of 5z2s
CRYSTAL STRUCTURE OF DUX4-HD2 DOMAIN
分子名称:Double homeobox protein 4
著者Dong, X., Zhang, W., Wu, H., Huang, J., Zhang, M., Wang, P., Zhang, H., Chen, Z., Chen, S., Meng, G.
登録日2018-01-03
公開日2018-04-04
最終更新日2018-06-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis of DUX4/IGH-driven transactivation.
Leukemia, 32, 2018
5Z2T
  • Download 5z2t
  • View 5z2t
Molmil generated image of 5z2t
CRYSTAL STRUCTURE OF DNA-BOUND DUX4-HD2
分子名称:Double homeobox protein 4, 5'-D(*TP*TP*CP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*TP*T)-3', 5'-D(P*AP*AP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*GP*T)-3'
著者Dong, X., Zhang, W., Wu, H., Huang, J., Zhang, M., Wang, P., Zhang, H., Chen, Z., Chen, S., Meng, G.
登録日2018-01-04
公開日2018-04-04
最終更新日2018-06-20
実験手法X-RAY DIFFRACTION (2.623 Å)
主引用文献Structural basis of DUX4/IGH-driven transactivation.
Leukemia, 32, 2018
6A8R
  • Download 6a8r
  • View 6a8r
Molmil generated image of 6a8r
CRYSTAL STRUCTURE OF DUX4 HD2 DOMAIN ASSOCIATED WITH ERG DNA BINDING SITE
分子名称:Double homeobox protein 4, DNA (5'-D(P*TP*GP*AP*TP*GP*AP*GP*AP*TP*T)-3'), DNA (5'-D(P*AP*AP*TP*CP*TP*CP*AP*TP*CP*A)-3')
著者Dong, X., Zhang, H., Cheng, N., Meng, G.
登録日2018-07-10
公開日2018-10-24
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献DUX4HD2-DNAERGstructure reveals new insight into DUX4-Responsive-Element.
Leukemia, 33, 2019
6N29
  • Download 6n29
  • View 6n29
Molmil generated image of 6n29
CRYSTAL STRUCTURE OF MONOMERIC VON WILLEBRAND FACTOR D`D3 ASSEMBLY
分子名称:von Willebrand factor, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ...
著者Dong, X., Arndt, J.W., Springer, T.A.
登録日2018-11-12
公開日2019-01-23
最終更新日2019-04-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The von Willebrand factor D'D3 assembly and structural principles for factor VIII binding and concatemer biogenesis.
Blood, 133, 2019
5VBT
  • Download 5vbt
  • View 5vbt
Molmil generated image of 5vbt
CRYSTAL STRUCTURE OF A HIGHLY SPECIFIC AND POTENT USP7 UBIQUITIN VARIANT INHIBITOR
分子名称:UBH04
著者DONG, A., DONG, X., LIU, L., GUO, Y., LI, Y., ZHANG, W., WALKER, J.R., SIDHU, S., Bountra, C., Arrowsmith, C.H., Edwards, A.M., TONG, Y., Structural Genomics Consortium (SGC)
登録日2017-03-30
公開日2017-06-07
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Crystal structure of a highly specific and potent USP7 ubiquitin variant inhibitor
to be published
5YZ9
  • Download 5yz9
  • View 5yz9
Molmil generated image of 5yz9
ZINC FINGER DOMAIN OF METTL3-METTL14 N6-METHYLADENOSINE METHYLTRANSFERASE
分子名称:N6-adenosine-methyltransferase catalytic subunit, ZINC ION
著者Dong, X., Tang, C., Gong, Z., Yin, P., Huang, J.B.
登録日2017-12-13
公開日2018-03-28
最終更新日2019-03-27
実験手法SOLUTION NMR, SOLUTION SCATTERING
主引用文献Solution structure of the RNA recognition domain of METTL3-METTL14 N6-methyladenosine methyltransferase.
Protein Cell, 10, 2019
2L22
  • Download 2l22
  • View 2l22
Molmil generated image of 2l22
MUPIROCIN DIDOMAIN ACP
分子名称:Mupirocin didomain Acyl Carrier Protein
著者Dong, X., Williams, C., Crump, M.P., Wattana-amorn, P.
登録日2010-08-10
公開日2012-02-15
最終更新日2013-11-06
実験手法SOLUTION NMR
主引用文献A conserved motif flags acyl carrier proteins for beta-branching in polyketide synthesis.
Nat.Chem.Biol., 9, 2013
3EBM
  • Download 3ebm
  • View 3ebm
Molmil generated image of 3ebm
CRYSTAL STRUCTURE OF HUMAN TRANSLATIONALLY CONTROLLED TUMOUR ASSOCIATED PROTEIN (HTCTP) MUTANT E12V
分子名称:Translationally-controlled tumor protein
著者Yang, B., Dong, X., Zhong, C., Ding, J.
登録日2008-08-28
公開日2009-06-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular basis of the acceleration of the GDP-GTP exchange of human ras homolog enriched in brain by human translationally controlled tumor protein.
J.Biol.Chem., 284, 2009
3PPV
  • Download 3ppv
  • View 3ppv
Molmil generated image of 3ppv
CRYSTAL STRUCTURE OF AN ENGINEERED VWF A2 DOMAIN (N1493C AND C1670S)
分子名称:von Willebrand factor, SULFATE ION, CALCIUM ION
著者Zhou, M., Dong, X., Zhong, C., Ding, J.
登録日2010-11-25
公開日2011-05-04
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13
Blood, 117, 2011
3PPW
  • Download 3ppw
  • View 3ppw
Molmil generated image of 3ppw
CRYSTAL STRUCTURE OF THE D1596A MUTANT OF AN ENGINEERED VWF A2 DOMAIN (N1493C AND C1670S)
分子名称:von Willebrand factor, SODIUM ION
著者Zhou, M., Dong, X., Zhong, C., Ding, J.
登録日2010-11-25
公開日2011-05-04
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13
Blood, 117, 2011
<123>