Author results

2C7U
  • Download 2c7u
  • View 2c7u
Molmil generated image of 2c7u
CONFLICTING SELECTIVE FORCES AFFECT CD8 T-CELL RECEPTOR CONTACT SITES IN AN HLA-A2 IMMUNODOMINANT HIV EPITOPE.
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, BETA-2-MICROGLOBULIN, ...
Authors:Iversen, A.K., Stewart-Jones, G., Learn, G.H., Christie, N., Sylvester-Hviid, C., Armitage, A.E., Kaul, R., Beattie, T., Lee, J.K., Li, Y., Chotiyarnwong, P., Dong, T., Xu, X., Luscher, M.A., MacDonald, K., Ullum, H., Klarlund-Pedersen, B., Skinhoj, P., Fugger, J.L., Buus, S., Mullins, J.I., Jones, E.Y., van der Merwe, P.A., McMichael, A.J.
Deposit date:2005-11-29
Release date:2006-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Conflicting Selective Forces Affect T Cell Receptor Contacts in an Immunodominant Human Immunodeficiency Virus Epitope.
Nat.Immunol., 7, 2006
2V2W
  • Download 2v2w
  • View 2v2w
Molmil generated image of 2v2w
T CELL CROSS-REACTIVITY AND CONFORMATIONAL CHANGES DURING TCR ENGAGEMENT
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, BETA-2 MICROGLOBULIN, ...
Authors:Lee, J.K., Stewart-Jones, G., Dong, T., Harlos, K., Di Gleria, K., Dorrell, L., Douek, D.C., Van Der Merwe, P.A., Jones, E.Y., Mcmichael, A.J.
Deposit date:2007-06-07
Release date:2007-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:T Cell Cross-Reactivity and Conformational Changes During Tcr Engagement.
J.Exp.Med., 200, 2004
2V2X
  • Download 2v2x
  • View 2v2x
Molmil generated image of 2v2x
T CELL CROSS-REACTIVITY AND CONFORMATIONAL CHANGES DURING TCR ENGAGEMENT.
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, BETA-2 MICROGLOBULIN, ...
Authors:Lee, J.K., Stewart-Jones, G., Dong, T., harlos, K., Di Gleria, K., Dorrell, L., Douek, D.C., van der Merwe, P.A., Jones, E.Y., McMichael, A.J.
Deposit date:2007-06-07
Release date:2007-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:T Cell Cross-Reactivity and Conformational Changes During Tcr Engagement.
J.Exp.Med., 200, 2004
2HJK
  • Download 2hjk
  • View 2hjk
Molmil generated image of 2hjk
CRYSTAL STRUCTURE OF HLA-B5703 AND HIV-1 PEPTIDE
Descriptor:HLA class I histocompatibility antigen B-57, Beta-2-microglobulin, Gag protein
Authors:Gillespie, G.M.A., Stewart-Jones, G., Rengasamy, J., Beattie, T., Bwayo, J.J., Plummer, F.A.
Deposit date:2006-06-30
Release date:2006-10-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Strong TCR Conservation and Altered T Cell Cross-Reactivity Characterize a B*57-Restricted Immune Response in HIV-1 Infection.
J.Immunol., 177, 2006
2HJL
  • Download 2hjl
  • View 2hjl
Molmil generated image of 2hjl
CRYSTAL STRUCTURE OF HLA-B5703 AND HIV-1 PEPTIDE
Descriptor:HLA class I histocompatibility antigen B-57, Beta-2-microglobulin, Gag protein
Authors:Gillespie, G.M.A., Stewart-Jones, G., Rengasamy, J., Beattie, T., Bwayo, J.J., Plummer, F.A.
Deposit date:2006-06-30
Release date:2006-10-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Strong TCR Conservation and Altered T Cell Cross-Reactivity Characterize a B*57-Restricted Immune Response in HIV-1 Infection.
J.Immunol., 177, 2006
5WJL
  • Download 5wjl
  • View 5wjl
Molmil generated image of 5wjl
CRYSTAL STRUCTURE OF HLA-A*11:01 WITH GTS1 PEPTIDE
Descriptor:HLA class I histocompatibility antigen, A-11 alpha chain, Beta-2-microglobulin, ...
Authors:Gras, S., Rossjohn, J.
Deposit date:2017-07-23
Release date:2017-09-20
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8(+) T cell response.
Nat. Immunol., 18, 2017
5WJN
  • Download 5wjn
  • View 5wjn
Molmil generated image of 5wjn
CRYSTAL STRUCTURE OF HLA-A*11:01-GTS3
Descriptor:HLA class I histocompatibility antigen, A-11 alpha chain, Beta-2-microglobulin, ...
Authors:Gras, S., Rossjohn, J.
Deposit date:2017-07-23
Release date:2017-09-20
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8(+) T cell response.
Nat. Immunol., 18, 2017
5WKF
  • Download 5wkf
  • View 5wkf
Molmil generated image of 5wkf
D30 TCR IN COMPLEX WITH HLA-A*11:01-GTS1
Descriptor:HLA class I histocompatibility antigen, A-11 alpha chain, Beta-2-microglobulin, ...
Authors:Gras, S., Rossjohn, J.
Deposit date:2017-07-25
Release date:2017-09-20
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8(+) T cell response.
Nat. Immunol., 18, 2017
5WKH
  • Download 5wkh
  • View 5wkh
Molmil generated image of 5wkh
D30 TCR IN COMPLEX WITH HLA-A*11:01-GTS3
Descriptor:HLA class I histocompatibility antigen, A-11 alpha chain, Beta-2-microglobulin, ...
Authors:Gras, S., Rossjohn, J.
Deposit date:2017-07-25
Release date:2017-09-20
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8(+) T cell response.
Nat. Immunol., 18, 2017
6G4Y
  • Download 6g4y
  • View 6g4y
Molmil generated image of 6g4y
CRYSTAL STRUCTURE OF MURINE NF-KAPPAB INDUCING KINASE (NIK) IN COMPLEX WITH COMPOUND 1A
Descriptor:Mitogen-activated protein kinase kinase kinase 14, SULFATE ION, 10-[2-[(3~{R})-1-methyl-3-oxidanyl-2-oxidanylidene-pyrrolidin-3-yl]ethynyl]-~{N}3-(oxan-4-yl)-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepine-2,3-dicarboxamide
Authors:Hole, A.J., Hymowitz, S.G., McEwan, P.A.
Deposit date:2018-03-28
Release date:2018-07-04
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Scaffold-Hopping Approach To Discover Potent, Selective, and Efficacious Inhibitors of NF-kappa B Inducing Kinase.
J. Med. Chem., 61, 2018
6G4Z
  • Download 6g4z
  • View 6g4z
Molmil generated image of 6g4z
CRYSTAL STRUCTURE OF MURINE NF-KAPPAB INDUCING KINASE (NIK) IN COMPLEX WITH COMPOUND 2F
Descriptor:Mitogen-activated protein kinase kinase kinase 14, 5-fluoranyl-1-[4-[2-[(3~{R})-1-methyl-3-oxidanyl-2-oxidanylidene-pyrrol-3-yl]ethynyl]pyridin-2-yl]indazole-3-carboxamide
Authors:Leonardo-Silvestre, H., McEwan, P.A., Hymowitz, S.G.
Deposit date:2018-03-28
Release date:2018-07-04
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Scaffold-Hopping Approach To Discover Potent, Selective, and Efficacious Inhibitors of NF-kappa B Inducing Kinase.
J. Med. Chem., 61, 2018
6II4
  • Download 6ii4
  • View 6ii4
Molmil generated image of 6ii4
CRYSTAL STRUCTURE OF H7 HEMAGGLUTININ FROM A/ANHUI/1/2013 IN COMPLEX WITH A HUMAN NEUTRALIZING ANTIBODY L4A-14
Descriptor:Hemagglutinin, Heavy chain of L4A-14 Fab, Light chain of L4A-14 Fab
Authors:Jiang, H.H., Shi, Y., Qi, J., Gao, G.F.
Deposit date:2018-10-03
Release date:2018-10-24
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure-function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans.
Nat Microbiol, 4, 2019
6II8
  • Download 6ii8
  • View 6ii8
Molmil generated image of 6ii8
CRYSTAL STRUCTURE OF H7 HEMAGGLUTININ FROM A/ANHUI/1/2013 IN COMPLEX WITH A HUMAN NEUTRALIZING ANTIBODY L4B-18
Descriptor:Hemagglutinin, Heavy chain of L4B-18 Fab, Light chain of L4B-18 Fab, ...
Authors:Jiang, H.H., Shi, Y., Qi, J., Gao, G.F.
Deposit date:2018-10-03
Release date:2018-10-24
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Structure-function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans.
Nat Microbiol, 4, 2019
6II9
  • Download 6ii9
  • View 6ii9
Molmil generated image of 6ii9
CRYSTAL STRUCTURE OF H7 HEMAGGLUTININ FROM A/ANHUI/1/2013 IN COMPLEX WITH A HUMAN NEUTRALIZING ANTIBODY L3A-44
Descriptor:Hemagglutinin, Heavy chain of L3A-44 Fab, Light chain of L3A-44 Fab, ...
Authors:Jiang, H.H., Shi, Y., Qi, J., Gao, G.F.
Deposit date:2018-10-03
Release date:2018-10-24
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure-function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans.
Nat Microbiol, 4, 2019