2A6L
| Dihydrodipicolinate synthase (E. coli)- mutant R138H | Descriptor: | Dihydrodipicolinate synthase, POTASSIUM ION | Authors: | Dobson, R.C, Devenish, S.R, Turner, L.A, Clifford, V.R, Pearce, F.G, Jameson, G.B, Gerrard, J.A. | Deposit date: | 2005-07-03 | Release date: | 2005-10-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Role of Arginine 138 in the Catalysis and Regulation of Escherichia coli Dihydrodipicolinate Synthase. Biochemistry, 44, 2005
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2A6N
| Dihydrodipicolinate synthase (E. coli)- mutant R138A | Descriptor: | Dihydrodipicolinate synthase, POTASSIUM ION | Authors: | Dobson, R.C, Devenish, S.R, Turner, L.A, Clifford, V.R, Pearce, F.G, Jameson, G.B, Gerrard, J.A. | Deposit date: | 2005-07-03 | Release date: | 2005-10-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Role of Arginine 138 in the Catalysis and Regulation of Escherichia coli Dihydrodipicolinate Synthase. Biochemistry, 44, 2005
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3TUU
| Structure of dihydrodipicolinate synthase from the common grapevine | Descriptor: | BROMIDE ION, CHLORIDE ION, dihydrodipicolinate synthase | Authors: | Perugini, M.A, Dobson, R.C, Atkinson, S.C. | Deposit date: | 2011-09-19 | Release date: | 2012-07-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal, Solution and In silico Structural Studies of Dihydrodipicolinate Synthase from the Common Grapevine. Plos One, 7, 2012
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2PUR
| Structure of dihydrodipicolinate synthase mutant Thr44Ser at 1.7 A. | Descriptor: | Dihydrodipicolinate synthase, GLYCEROL, PHOSPHATE ION, ... | Authors: | Dobson, R.C.J, Jameson, G.B, Gerrard, J.A. | Deposit date: | 2007-05-09 | Release date: | 2008-05-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Specificity versus catalytic potency: The role of threonine 44 in Escherichia coli dihydrodipicolinate synthase mediated catalysis. Biochimie, 91, 2009
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1YXD
| Structure of E. coli dihydrodipicolinate synthase bound with allosteric inhibitor (S)-lysine to 2.0 A | Descriptor: | CHLORIDE ION, LYSINE, POTASSIUM ION, ... | Authors: | Dobson, R.C.J, Griffin, M.D.W, Jameson, G.B, Gerrard, J.A. | Deposit date: | 2005-02-20 | Release date: | 2005-08-02 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance. Acta Crystallogr.,Sect.D, 61, 2005
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1YXC
| Structure of E. coli dihydrodipicolinate synthase to 1.9 A | Descriptor: | CHLORIDE ION, POTASSIUM ION, dihydrodipicolinate synthase | Authors: | Dobson, R.C.J, Griffin, M.D.W, Jameson, G.B, Gerrard, J.A. | Deposit date: | 2005-02-20 | Release date: | 2005-08-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance. Acta Crystallogr.,Sect.D, 61, 2005
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4TLJ
| Ultra-high resolution crystal structure of caprine Beta-lactoglobulin | Descriptor: | 1,4-BUTANEDIOL, Beta-lactoglobulin | Authors: | Crowther, J.M, Jameson, G.B, Suzuki, H, Dobson, R.C.J. | Deposit date: | 2014-05-30 | Release date: | 2014-06-18 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.17 Å) | Cite: | Ultra-high resolution crystal structure of recombinant caprine beta-lactoglobulin. Febs Lett., 588, 2014
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8UUB
| Structure of hypothiocyanous acid reductase (Har) from Streptococcus pneumoniae | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, MALONATE ION, Oxidoreductase, ... | Authors: | Shearer, H.L, Currie, M.J, Dickerhof, N, Dobson, R.C.J. | Deposit date: | 2023-10-31 | Release date: | 2024-04-17 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Hypothiocyanous acid reductase is critical for host colonization and infection by Streptococcus pneumoniae J.Biol.Chem., 2024
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5KZD
| N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus with bound sialic acid alditol | Descriptor: | (2~{S},4~{S},5~{R},6~{R},7~{S},8~{R})-5-acetamido-2,4,6,7,8,9-hexakis(oxidanyl)nonanoic acid, N-acetylneuraminate lyase | Authors: | North, R.A, Watson, A.J.A, Pearce, F.G, Muscroft-Taylor, A.C, Friemann, R, Fairbanks, A.J, Dobson, R.C.J. | Deposit date: | 2016-07-25 | Release date: | 2017-01-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.334 Å) | Cite: | Structure and inhibition of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus. FEBS Lett., 590, 2016
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5DPT
| Crystal structure of PLEKHM1 LIR-fused human GABARAPL1_2-117 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Pleckstrin homology domain-containing family M member 1, Gamma-aminobutyric acid receptor-associated protein-like 1,Gamma-aminobutyric acid receptor-associated protein-like 1 | Authors: | Ravichandran, A.C, Suzuki, H, Dobson, R.C.J. | Deposit date: | 2015-09-14 | Release date: | 2016-09-28 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural and functional analysis of the GABARAP interaction motif (GIM). EMBO Rep., 18, 2017
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5DPS
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5DPW
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5DPR
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5KZE
| N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus | Descriptor: | GLYCEROL, N-acetylneuraminate lyase, SULFATE ION | Authors: | North, R.A, Watson, A.J.A, Pearce, F.G, Muscroft-Taylor, A.C, Friemann, R, Fairbanks, A.J, Dobson, R.C.J. | Deposit date: | 2016-07-25 | Release date: | 2017-01-11 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Structure and inhibition of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus. FEBS Lett., 590, 2016
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3HIJ
| Crystal structure of dihydrodipicolinate synthase from Bacillus anthracis in complex with its substrate, pyruvate | Descriptor: | Dihydrodipicolinate synthase, GLYCEROL, SODIUM ION | Authors: | Voss, J.E, Scally, S.W, Dobson, R.C.J, Perugini, M.A. | Deposit date: | 2009-05-20 | Release date: | 2009-11-24 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Substrate-mediated Stabilization of a Tetrameric Drug Target Reveals Achilles Heel in Anthrax. J.Biol.Chem., 285, 2010
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2OJP
| The crystal structure of a dimeric mutant of Dihydrodipicolinate synthase from E.coli- DHDPS-L197Y | Descriptor: | Dihydrodipicolinate synthase, GLYCEROL | Authors: | Griffin, M.D.W, Dobson, R.C.J, Antonio, L, Perugini, M.A, Jameson, G.B, Gerrard, J.A. | Deposit date: | 2007-01-13 | Release date: | 2008-01-01 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Evolution of quaternary structure in a homotetrameric enzyme. J.Mol.Biol., 380, 2008
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3DU0
| E. coli dihydrodipicolinate synthase with first substrate, pyruvate, bound in active site | Descriptor: | CHLORIDE ION, Dihydrodipicolinate synthase, GLYCEROL, ... | Authors: | Dobson, R.C.J, Devenish, S.R.A, Gerrard, J.A, Jameson, G.B. | Deposit date: | 2008-07-16 | Release date: | 2008-11-18 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The high-resolution structure of dihydrodipicolinate synthase from Escherichia coli bound to its first substrate, pyruvate. Acta Crystallogr.,Sect.F, 64, 2008
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4C1L
| Crystal structure of pyrococcus furiosus 3-deoxy-D-arabino- heptulosonate 7-phosphate synthase I181D interface mutant | Descriptor: | 2-dehydro-3-deoxyphosphoheptonate aldolase, CHLORIDE ION, MANGANESE (II) ION, ... | Authors: | Nazmi, A.R, Schofield, L.R, Dobson, R.C.J, Jameson, G.B, Parker, E.J. | Deposit date: | 2013-08-13 | Release date: | 2013-11-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Destabilization of the homotetrameric assembly of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from the hyperthermophile Pyrococcus furiosus enhances enzymatic activity. J. Mol. Biol., 426, 2014
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4EOU
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3PB0
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3PB2
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3I7Q
| Dihydrodipicolinate synthase mutant - K161A | Descriptor: | Dihydrodipicolinate synthase, GLYCEROL, PHOSPHATE ION, ... | Authors: | Dobson, R.C.J, Jameson, G.B, Gerrard, J.A, Soares da Costa, T.P. | Deposit date: | 2009-07-08 | Release date: | 2010-04-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase? Biochimie, 92, 2010
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3I7R
| Dihydrodipicolinate synthase - K161R | Descriptor: | CHLORIDE ION, Dihydrodipicolinate synthase, GLYCEROL, ... | Authors: | Dobson, R.C.J, Jameson, G.B, Gerrard, J.A, Soares da Costa, T.P. | Deposit date: | 2009-07-08 | Release date: | 2010-04-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase? Biochimie, 92, 2010
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3I7S
| Dihydrodipicolinate synthase mutant - K161A - with the substrate pyruvate bound in the active site. | Descriptor: | Dihydrodipicolinate synthase, GLYCEROL, PHOSPHATE ION, ... | Authors: | Dobson, R.C.J, Jameson, G.B, Gerrard, J.A, Soares da Costa, T.P. | Deposit date: | 2009-07-08 | Release date: | 2010-04-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase? Biochimie, 92, 2010
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3WAL
| Crystal structure of human LC3A_2-121 | Descriptor: | D-MALATE, Microtubule-associated proteins 1A/1B light chain 3A | Authors: | Suzuki, H, Tabata, K, Morita, E, Kawasaki, M, Kato, R, Dobson, R.C.J, Yoshimori, T, Wakatsuki, S. | Deposit date: | 2013-05-06 | Release date: | 2013-12-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism. Structure, 22, 2014
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