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5VYC
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BU of 5vyc by Molmil
Crystal structure of the human 40S ribosomal subunit in complex with DENR-MCT-1.
Descriptor: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ...
Authors:Lomakin, I.B, Stolboushkina, E.A, Vaidya, A.T, Garber, M.B, Dmitriev, S.E, Steitz, T.A.
Deposit date:2017-05-24
Release date:2017-07-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (6 Å)
Cite:Crystal Structure of the Human Ribosome in Complex with DENR-MCT-1.
Cell Rep, 20, 2017
5W2F
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BU of 5w2f by Molmil
Crystal Structure of the C-terminal Domain of Human eIF2D at 1.4 A resolution
Descriptor: Eukaryotic translation initiation factor 2D, FORMIC ACID
Authors:Vaidya, A.T, Lomakin, I.B, Joseph, N.N, Dmitriev, S.E, Steitz, T.A.
Deposit date:2017-06-06
Release date:2017-08-02
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal Structure of the C-terminal Domain of Human eIF2D and Its Implications on Eukaryotic Translation Initiation.
J. Mol. Biol., 429, 2017
6MS4
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BU of 6ms4 by Molmil
Crystal structure of the DENR-MCT-1 complex
Descriptor: Density-regulated protein, GLYCEROL, Malignant T-cell-amplified sequence 1, ...
Authors:Lomakin, I.B, Steitz, T.A, Dmitriev, S.E.
Deposit date:2018-10-16
Release date:2019-01-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Crystal structure of the DENR-MCT-1 complex revealed zinc-binding site essential for heterodimer formation.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
5I4L
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BU of 5i4l by Molmil
Crystal structure of Amicoumacin A bound to the yeast 80S ribosome
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Prokhorova, I.V, Yusupova, G, Yusupov, M.
Deposit date:2016-02-12
Release date:2016-06-22
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Amicoumacin A induces cancer cell death by targeting the eukaryotic ribosome.
Sci Rep, 6, 2016
6Y6X
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BU of 6y6x by Molmil
Tetracenomycin X bound to the human ribosome
Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Buschauer, R, Cheng, J, Berninghausen, O, Beckmann, R, Wilson, D.N.
Deposit date:2020-02-27
Release date:2020-07-08
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel.
Nat.Chem.Biol., 16, 2020
6Y69
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BU of 6y69 by Molmil
Cryo-EM structure of an Escherichia coli 70S ribosome in complex with antibiotic TetracenomycinX
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Wieland, M, Wilson, D.N.
Deposit date:2020-02-26
Release date:2020-07-01
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel.
Nat.Chem.Biol., 16, 2020

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