Author results

1A2O
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STRUCTURAL BASIS FOR METHYLESTERASE CHEB REGULATION BY A PHOSPHORYLATION-ACTIVATED DOMAIN
Descriptor:CHEB METHYLESTERASE
Authors:Djordjevic, S., Goudreau, P.N., Xu, Q., Stock, A.M., West, A.H.
Deposit date:1998-01-06
Release date:1998-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for methylesterase CheB regulation by a phosphorylation-activated domain.
Proc.Natl.Acad.Sci.USA, 95, 1998
1AF7
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CHER FROM SALMONELLA TYPHIMURIUM
Descriptor:CHEMOTAXIS RECEPTOR METHYLTRANSFERASE CHER, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Djordjevic, S., Stock, A.M.
Deposit date:1997-03-22
Release date:1998-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the chemotaxis receptor methyltransferase CheR suggests a conserved structural motif for binding S-adenosylmethionine.
Structure, 5, 1997
1BC5
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CHEMOTAXIS RECEPTOR RECOGNITION BY PROTEIN METHYLTRANSFERASE CHER
Descriptor:CHEMOTAXIS RECEPTOR METHYLTRANSFERASE, CHEMOTAXIS RECEPTOR, COBALT (II) ION, ...
Authors:Djordjevic, S., Stock, A.M.
Deposit date:1998-05-05
Release date:1998-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Chemotaxis receptor recognition by protein methyltransferase CheR.
Nat.Struct.Biol., 5, 1998
1BUC
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THREE-DIMENSIONAL STRUCTURE OF BUTYRYL-COA DEHYDROGENASE FROM MEGASPHAERA ELSDENII
Descriptor:BUTYRYL-COA DEHYDROGENASE, ACETOACETYL-COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Djordjevic, S., Pace, C.P., Stankovich, M.T., Kim, J.J.P.
Deposit date:1994-09-06
Release date:1995-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three-dimensional structure of butyryl-CoA dehydrogenase from Megasphaera elsdenii.
Biochemistry, 34, 1995
1J04
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STRUCTURAL MECHANISM OF ENZYME MISTARGETING IN HEREDITARY KIDNEY STONE DISEASE IN VITRO
Descriptor:alanine--glyoxylate aminotransferase, (AMINOOXY)ACETIC ACID, GLYCEROL
Authors:Zhang, X., Djordjevic, S., Bartlam, M., Ye, S., Rao, Z., Danpure, C.J.
Deposit date:2002-10-30
Release date:2003-11-11
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural implications of a G170R mutation of alanine:glyoxylate aminotransferase that is associated with peroxisome-to-mitochondrion mistargeting.
Acta Crystallogr.,Sect.F, 66, 2010
6ESK
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STRUCTURE OF THE APO FORM OF AIOX FROM RHIZOBIUM SP. STR. NT-26
Descriptor:Putative periplasmic phosphite-binding-like protein (Pbl) PtxB-like protein designated AioX, GLYCEROL
Authors:Djordjevic, S., Badilla, C., Cole, A., Santini, J.
Deposit date:2017-10-20
Release date:2018-10-17
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A new family of periplasmic-binding proteins that sense arsenic oxyanions.
Sci Rep, 8, 2018
6ESV
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STRUCTURE OF THE PHOSPHATE-BOUND FORM OF AIOX FROM RHIZOBIUM SP. STR. NT-26
Descriptor:Putative periplasmic phosphite-binding-like protein (Pbl) PtxB-like protein designated AioX, PHOSPHATE ION
Authors:Djordjevic, S., Badilla, C., Cole, A., Santini, J.
Deposit date:2017-10-24
Release date:2018-10-17
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:A new family of periplasmic-binding proteins that sense arsenic oxyanions.
Sci Rep, 8, 2018
6EU7
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STRUCTURE OF THE ARSENITE-BOUND FORM OF AIOX FROM RHIZOBIUM SP. STR. NT-26
Descriptor:Putative periplasmic phosphite-binding-like protein (Pbl) PtxB-like protein designated AioX
Authors:Djordjevic, S., Badilla, C., Cole, A., Santini, J.
Deposit date:2017-10-28
Release date:2018-10-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:A new family of periplasmic-binding proteins that sense arsenic oxyanions.
Sci Rep, 8, 2018
3E0U
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CRYSTAL STRUCTURE OF T. CRUZI GPX1
Descriptor:Glutathione peroxidase, AMMONIUM ION, GLYCEROL
Authors:Patel, S.H., Hussain, S., Harris, R., Driscoll, P., Djordjevic, S.
Deposit date:2008-08-01
Release date:2009-08-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insights into the catalytic mechanism of Trypanosoma cruzi GPXI (glutathione peroxidase-like enzyme I).
Biochem.J., 425, 2010
6FMC
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NEUROPILIN1-B1 DOMAIN IN COMPLEX WITH EG01377, 0.9 ANGSTROM STRUCTURE
Descriptor:Neuropilin-1, (2~{S})-2-[[3-[[5-[4-(aminomethyl)phenyl]-1-benzofuran-7-yl]sulfonylamino]thiophen-2-yl]carbonylamino]-5-carbamimidamido-pentanoic acid
Authors:Yelland, T., Djordjevic, S., Fotinou, K., Selwood, D., Zachary, I., Frankel, P.
Deposit date:2018-01-30
Release date:2018-10-17
Method:X-RAY DIFFRACTION (0.9 Å)
Cite:Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGF beta ) Production in Regulatory T-Cells.
J. Med. Chem., 61, 2018
6FMF
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NEUROPILIN-1 B1 DOMAIN IN COMPLEX WITH EG01377; 2.8 ANGSTROM STRUCTURE
Descriptor:Neuropilin-1, (2~{S})-2-[[3-[[5-[4-(aminomethyl)phenyl]-1-benzofuran-7-yl]sulfonylamino]thiophen-2-yl]carbonylamino]-5-carbamimidamido-pentanoic acid, trifluoroacetic acid
Authors:Yelland, T., Djordjevic, S., Selwood, D., Zachary, I., Frankel, P.
Deposit date:2018-01-31
Release date:2018-10-17
Method:X-RAY DIFFRACTION (2.811 Å)
Cite:Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGF beta ) Production in Regulatory T-Cells.
J. Med. Chem., 61, 2018
1EVV
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CRYSTAL STRUCTURE OF YEAST PHENYLALANINE TRANSFER RNA AT 2.0 A RESOLUTION
Descriptor:PHENYLALANINE TRANSFER RNA, MAGNESIUM ION, SPERMINE
Authors:Jovine, L., Djordjevic, S., Rhodes, D.
Deposit date:2000-04-20
Release date:2000-05-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of yeast phenylalanine tRNA at 2.0 A resolution: cleavage by Mg(2+) in 15-year old crystals.
J.Mol.Biol., 301, 2000
1GU9
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS ALKYLPEROXIDASE AHPD
Descriptor:ALKYLHYDROPEROXIDASE D
Authors:Nunn, C.M., Djordjevic, S., Hillas, P.J., Nishida, C., Ortiz de Montellano, P.R.
Deposit date:2002-01-24
Release date:2002-02-14
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Crystal Structure of Mycobacterium Tuberculosis Alkylhydroperoxidase Ahpd, a Potential Target for Antitubercular Drug Design
J.Biol.Chem., 277, 2002
1LW1
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS ALKYLPEROXIDASE AHPD H137F MUTANT
Descriptor:ALKYLHYDROPEROXIDASE D
Authors:Nunn, C.M., Djordjevic, S., Ortiz de Montellano, P.R.
Deposit date:2002-05-30
Release date:2002-07-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Mechanism of Mycobacterium tuberculosis Alkylhydroperoxidase AhpD as Defined by Mutagenesis, Crystallography, and Kinetics
J.Biol.Chem., 278, 2003
1ME5
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS ALKYLPEROXIDASE AHPD H132Q MUTANT
Descriptor:ALKYLHYDROPEROXIDASE D
Authors:Nunn, C.M., Djordjevic, S., Ortiz de Montellano, P.R.
Deposit date:2002-08-08
Release date:2002-09-11
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The mechanism of Mycobacterium tuberculosis alkylhydroperoxidase AhpD as defined by mutagenesis, crystallography, and kinetics.
J.Biol.Chem., 278, 2003
1Q31
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CRYSTAL STRUCTURE OF THE TOBACCO ETCH VIRUS PROTEASE C151A MUTANT
Descriptor:Nuclear inclusion protein A, BETA-MERCAPTOETHANOL
Authors:Nunn, C.M., Djordjevic, S., George, R.R., Urquhart, G.T., Chao, L.H., Tsuchiya, Y.
Deposit date:2003-07-28
Release date:2004-11-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of tobacco etch virus protease shows the protein C terminus bound within the active site.
J.Mol.Biol., 350, 2005
2AR5
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CRYSTAL STRUCTURE OF THE MAMMALIAN C2ALPHA-PI3 KINASE PX-DOMAIN
Descriptor:Phosphoinositide 3-kinase, GLYCEROL
Authors:Parkinson, G.N., Vines, D., Driscoll, P.C., Djordjevic, S.
Deposit date:2005-08-19
Release date:2006-10-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Ligand-binding specificity of PI3Kinase C2alpha PX domain.
To be Published
2I08
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SOLVATION EFFECT IN CONFORMATIONAL CHANGES OF EF-HAND PROTEINS: X-RAY STRUCTURE OF CA2+-SATURATED DOUBLE MUTANT Q41L-K75I OF N-DOMAIN OF CALMODULIN
Descriptor:Calmodulin, CALCIUM ION, GLYCEROL
Authors:Ababou, A., Parkinson, G.N., Desjarlais, J.R., Djordjevic, S.
Deposit date:2006-08-10
Release date:2007-08-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Solvation effect in conformational changes of EF-hand proteins: X-ray structure of double mutant Q41L-K75I of N-domain of calmodulin
To be Published
2REA
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CRYSTAL STRUCTURES OF C2ALPHA-PI3 KINASE PX-DOMAIN DOMAIN INDICATE CONFORMATIONAL CHANGE ASSOCIATED WITH LIGAND BINDING.
Descriptor:Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide
Authors:Parkinson, G.N., Vines, D., Driscoll, P.C., Djordjevic, S.
Deposit date:2007-09-26
Release date:2007-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of PI3K-C2alpha PX domain indicate conformational change associated with ligand binding
Bmc Struct.Biol., 8, 2008
2RED
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CRYSTAL STRUCTURES OF C2ALPHA-PI3 KINASE PX-DOMAIN DOMAIN INDICATE CONFORMATIONAL CHANGE ASSOCIATED WITH LIGAND BINDING.
Descriptor:Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide, GLYCEROL
Authors:Parkinson, G.N., Vines, D., Driscoll, P.C., Djordjevic, S.
Deposit date:2007-09-26
Release date:2007-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of PI3K-C2alpha PX domain indicate conformational change associated with ligand binding
Bmc Struct.Biol., 8, 2008
3I97
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B1 DOMAIN OF HUMAN NEUROPILIN-1 BOUND WITH SMALL MOLECULE EG00229
Descriptor:Neuropilin-1, (S)-2-(3-(benzo[c][1,2,5]thiadiazole-4-sulfonamido)thiophene-2-carboxamido)-5-guanidinopentanoic acid, GLYCEROL
Authors:Allerston, C.K., Djordjevic, S.
Deposit date:2009-07-10
Release date:2010-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction.
J.Med.Chem., 53, 2010
3O7W
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THE CRYSTAL STRUCTURE OF HUMAN LEUCINE CARBOXYL METHYLTRANSFERASE 1
Descriptor:Leucine carboxyl methyltransferase 1, GLYCEROL, S-ADENOSYLMETHIONINE, ...
Authors:Tsai, M.L., Cronin, N., Djordjevic, S.
Deposit date:2010-08-01
Release date:2010-09-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of human leucine carboxyl methyltransferase 1 that regulates protein phosphatase PP2A
Acta Crystallogr.,Sect.D, 67, 2011
4RN5
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B1 DOMAIN OF HUMAN NEUROPILIN-1 WITH ACETATE ION IN A LIGAND-BINDING SITE
Descriptor:Neuropilin-1, ACETATE ION, ZINC ION, ...
Authors:Allerston, C.K., Yelland, T.S., Jarvis, A., Jenkins, K., Winfield, N., Cheng, L., Jia, H., Zachary, I., Selwood, D.L., Djordjevic, S.
Deposit date:2014-10-23
Release date:2015-10-28
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Conserved water molecules in a ligand-binding site of neuropilin-1
To be Published
5DN2
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HUMAN NRP2 B1 DOMAIN IN COMPLEX WITH THE PEPTIDE CORRESPONDING TO THE C-TERMINUS OF VEGF-A
Descriptor:Neuropilin-2, Vascular endothelial growth factor A, 1,4-DIETHYLENE DIOXIDE, ...
Authors:Tsai, Y.C.I., Frankel, P., Fotinou, C., Rana, R., Zachary, I., Djordjevic, S.
Deposit date:2015-09-09
Release date:2016-07-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural studies of neuropilin-2 reveal a zinc ion binding site remote from the vascular endothelial growth factor binding pocket.
Febs J., 283, 2016
5DQ0
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STRUCTURE OF HUMAN NEUROPILIN-2 B1 DOMAIN WITH NOVEL AND UNIQUE ZINC BINDING SITE
Descriptor:Neuropilin-2, ZINC ION, CHLORIDE ION, ...
Authors:Tsai, Y.I., Rana, R.R., Zachary, I., Djordjevic, S.
Deposit date:2015-09-14
Release date:2016-09-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:To be published
To Be Published
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