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1VHR
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BU of 1vhr by Molmil
HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE VHR, SULFATE ION
Authors:Yuvaniyama, J, Denu, J.M, Dixon, J.E, Saper, M.A.
Deposit date:1996-02-20
Release date:1996-06-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the dual specificity protein phosphatase VHR.
Science, 272, 1996
8F48
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BU of 8f48 by Molmil
Human CASQ1 mutant - S248E
Descriptor: Calsequestrin-1
Authors:Mayfield, J.E, Dixon, J.E.
Deposit date:2022-11-10
Release date:2023-12-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Human CASQ1 mutant - S248E
To Be Published
1BYR
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BU of 1byr by Molmil
CRYSTAL STRUCTURE OF A PHOSPHOLIPASE D FAMILY MEMBER, NUC FROM SALMONELLA TYPHIMURIUM
Descriptor: PROTEIN (ENDONUCLEASE)
Authors:Stuckey, J.A, Dixon, J.E.
Deposit date:1998-10-19
Release date:1999-10-19
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a phospholipase D family member.
Nat.Struct.Biol., 6, 1999
1BYS
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BU of 1bys by Molmil
CRYSTAL STRUCTURE OF NUC COMPLEXED WITH TUNGSTATE
Descriptor: PROTEIN (ENDONUCLEASE), TUNGSTATE(VI)ION
Authors:Stuckey, J.A, Dixon, J.E.
Deposit date:1998-10-19
Release date:1999-10-19
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a phospholipase D family member.
Nat.Struct.Biol., 6, 1999
2QH7
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BU of 2qh7 by Molmil
MitoNEET is a uniquely folded 2Fe-2S outer mitochondrial membrane protein stabilized by pioglitazone
Descriptor: FE2/S2 (INORGANIC) CLUSTER, Zinc finger CDGSH-type domain 1
Authors:Paddock, M.L, Wiley, S.E, Axelrod, H.L, Cohen, A.E, Roy, M, Abresch, E.C, Capraro, D, Murphy, A.N, Nechushtai, R, Dixon, J.E, Jennings, P.A.
Deposit date:2007-06-30
Release date:2007-08-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:MitoNEET is a uniquely folded 2Fe 2S outer mitochondrial membrane protein stabilized by pioglitazone.
Proc.Natl.Acad.Sci.Usa, 104, 2007
1UKF
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BU of 1ukf by Molmil
Crystal Structure of Pseudomonas Avirulence Protein AvrPphB
Descriptor: Avirulence protein AVRPPH3
Authors:Zhu, M, Shao, F, Innes, R.W, Dixon, J.E, Xu, Z.
Deposit date:2003-08-21
Release date:2003-12-09
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:The crystal structure of Pseudomonas avirulence protein AvrPphB: a papain-like fold with a distinct substrate-binding site.
Proc.Natl.Acad.Sci.Usa, 101, 2004
1YTS
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BU of 1yts by Molmil
A LIGAND-INDUCED CONFORMATIONAL CHANGE IN THE YERSINIA PROTEIN TYROSINE PHOSPHATASE
Descriptor: SULFATE ION, YERSINIA PROTEIN TYROSINE PHOSPHATASE
Authors:Schubert, H.L, Stuckey, J.A, Fauman, E.B, Dixon, J.E, Saper, M.A.
Deposit date:1995-04-07
Release date:1995-07-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A ligand-induced conformational change in the Yersinia protein tyrosine phosphatase.
Protein Sci., 4, 1995
4ITR
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BU of 4itr by Molmil
Crystal Structure of IbpAFic2-H3717A in complex with adenylylated Cdc42
Descriptor: ADENOSINE MONOPHOSPHATE, Adenosine monophosphate-protein transferase and cysteine protease IbpA, Cell division control protein 42 homolog, ...
Authors:Xiao, J, Dixon, J.E.
Deposit date:2013-01-18
Release date:2013-02-20
Last modified:2023-06-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of Fic-mediated adenylylation.
Nat.Struct.Mol.Biol., 17, 2010
1YPT
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BU of 1ypt by Molmil
CRYSTAL STRUCTURE OF YERSINIA PROTEIN TYROSINE PHOSPHATASE AT 2.5 ANGSTROMS AND THE COMPLEX WITH TUNGSTATE
Descriptor: PROTEIN-TYROSINE PHOSPHATASE YERSINIA (CATALYTIC DOMAIN)
Authors:Stuckey, J.A, Schubert, H.L, Fauman, E.B, Zhang, Z.-Y, Dixon, J.E, Saper, M.A.
Deposit date:1994-09-16
Release date:1994-12-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of Yersinia protein tyrosine phosphatase at 2.5 A and the complex with tungstate.
Nature, 370, 1994
1LW3
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BU of 1lw3 by Molmil
Crystal Structure of Myotubularin-related protein 2 complexed with phosphate
Descriptor: Myotubularin-related protein 2, PHOSPHATE ION
Authors:Begley, M.J, Taylor, G.S, Kim, S.-A, Veine, D.M, Dixon, J.E, Stuckey, J.A.
Deposit date:2002-05-30
Release date:2003-10-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of a Phosphoinositide Phosphatase, MTMR2: Insights into Myotubular Myopathy and Charcot-Marie-Tooth Syndrome
Mol.Cell, 12, 2003
1M7R
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BU of 1m7r by Molmil
Crystal Structure of Myotubularin-related Protein-2 (MTMR2) Complexed with Phosphate
Descriptor: Myotubularin-related Protein-2, PHOSPHATE ION
Authors:Begley, M.J, Taylor, G.S, Kim, S.-A, Veine, D.M, Dixon, J.E, Stuckey, J.A.
Deposit date:2002-07-22
Release date:2003-10-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of a phosphoinositide phosphatase, MTMR2: insights into myotubular myopathy and Charcot-Marie-Tooth syndrome
Mol.Cell, 12, 2003
1DOF
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BU of 1dof by Molmil
THE CRYSTAL STRUCTURE OF ADENYLOSUCCINATE LYASE FROM PYROBACULUM AEROPHILUM: INSIGHTS INTO THERMAL STABILITY AND HUMAN PATHOLOGY
Descriptor: ADENYLOSUCCINATE LYASE
Authors:Toth, E.A, Yeates, T.O, Goedken, E, Dixon, J.E, Marqusee, S.
Deposit date:1999-12-20
Release date:2001-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of adenylosuccinate lyase from Pyrobaculum aerophilum reveals an intracellular protein with three disulfide bonds.
J.Mol.Biol., 301, 2000
1ZSQ
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BU of 1zsq by Molmil
Crystal Structure of MTMR2 in complex with phosphatidylinositol 3-phosphate
Descriptor: 1,2-ETHANEDIOL, 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE, Myotubularin-related protein 2
Authors:Begley, M.J, Taylor, G.S, Brock, M.A, Ghosh, P, Woods, V.L, Dixon, J.E.
Deposit date:2005-05-25
Release date:2006-01-31
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Molecular basis for substrate recognition by MTMR2, a myotubularin family phosphoinositide phosphatase
Proc.Natl.Acad.Sci.Usa, 103, 2006
1ZVR
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BU of 1zvr by Molmil
Crystal Structure of MTMR2 in complex with phosphatidylinositol 3,5-bisphosphate
Descriptor: (1S)-2-(1-HYDROXYBUTOXY)-1-{[(HYDROXY{[(2R,3S,5R,6S)-2,4,6-TRIHYDROXY-3,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTYRATE, 1,2-ETHANEDIOL, Myotubularin-related protein 2
Authors:Begley, M.J, Taylor, G.S, Brock, M.A, Ghosh, P, Woods, V.L, Dixon, J.E.
Deposit date:2005-06-02
Release date:2006-01-31
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Molecular basis for substrate recognition by MTMR2, a myotubularin family phosphoinositide phosphatase
Proc.Natl.Acad.Sci.Usa, 103, 2006
6K0J
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BU of 6k0j by Molmil
The co-crystal structure of DYRK2 with a small molecule inhibitor
Descriptor: 3-(2,7-dimethoxyacridin-9-yl)sulfanylpropan-1-amine, Dual specificity tyrosine-phosphorylation-regulated kinase 2
Authors:Tiantian, W, Xiao, J.
Deposit date:2019-05-06
Release date:2019-11-20
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.352 Å)
Cite:Inhibition of dual-specificity tyrosine phosphorylation-regulated kinase 2 perturbs 26S proteasome-addicted neoplastic progression.
Proc.Natl.Acad.Sci.USA, 116, 2019
5ZTN
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BU of 5ztn by Molmil
The crystal structure of human DYRK2 in complex with Curcumin
Descriptor: (1Z,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one, Dual specificity tyrosine-phosphorylation-regulated kinase 2
Authors:Ji, C.G, Xiao, J.Y.
Deposit date:2018-05-04
Release date:2018-07-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.496 Å)
Cite:Ancient drug curcumin impedes 26S proteasome activity by direct inhibition of dual-specificity tyrosine-regulated kinase 2.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5LN3
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BU of 5ln3 by Molmil
The human 26S Proteasome at 6.8 Ang.
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
Authors:Schweitzer, A, Beck, F, Sakata, E, Unverdorben, P.
Deposit date:2016-08-03
Release date:2017-03-22
Last modified:2017-05-24
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome.
Mol. Cell Proteomics, 16, 2017
3N3U
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BU of 3n3u by Molmil
Crystal Structure of IbpAFic2
Descriptor: Adenosine monophosphate-protein transferase ibpA, SULFATE ION, ZINC ION
Authors:Xiao, J.
Deposit date:2010-05-20
Release date:2010-07-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.846 Å)
Cite:Structural basis of Fic-mediated adenylylation.
Nat.Struct.Mol.Biol., 17, 2010
5GZA
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BU of 5gza by Molmil
protein O-mannose kinase
Descriptor: 2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose, 4-METHYL-2H-CHROMEN-2-ONE, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Xiao, J.
Deposit date:2016-09-27
Release date:2016-12-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of protein O-mannose kinase reveals a unique active site architecture
Elife, 5, 2016
5JDA
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BU of 5jda by Molmil
Bacillus cereus CotH kinase plus Mg2+/AMP
Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, ...
Authors:Tomchick, D.R, Tagliabracci, V.S, Sreelatha, A.
Deposit date:2016-04-15
Release date:2016-05-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.401 Å)
Cite:Phosphorylation of spore coat proteins by a family of atypical protein kinases.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JD9
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BU of 5jd9 by Molmil
Bacillus cereus CotH kinase
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, Spore coat protein H
Authors:Tomchick, D.R, Tagliabracci, V.S, Sreelatha, A.
Deposit date:2016-04-15
Release date:2016-05-18
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Phosphorylation of spore coat proteins by a family of atypical protein kinases.
Proc.Natl.Acad.Sci.USA, 113, 2016
4KQB
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BU of 4kqb by Molmil
crystal structure of the Golgi casein kinase with Mn/ADP bound
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Xiao, J.
Deposit date:2013-05-14
Release date:2013-06-26
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.045 Å)
Cite:Crystal structure of the Golgi casein kinase.
Proc.Natl.Acad.Sci.USA, 110, 2013
3CXB
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BU of 3cxb by Molmil
Crystal Structure of sifa and skip
Descriptor: Pleckstrin homology domain-containing family M member 2, Protein sifA
Authors:Huang, Z, Chai, J.
Deposit date:2008-04-24
Release date:2008-12-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure and function of Salmonella SifA indicate that its interactions with SKIP, SseJ, and RhoA family GTPases induce endosomal tubulation
Cell Host Microbe, 4, 2008
2I42
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BU of 2i42 by Molmil
Crystal structure of Yersinia protein tyrosine phosphatase complexed with vanadate, a transition state analogue
Descriptor: Tyrosine-protein phosphatase, VANADATE ION
Authors:Vijayalakshmi, J, Saper, M.A.
Deposit date:2006-08-21
Release date:2006-09-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Yersinia protein tyrosine phosphatase complexed with vanadate, a transition state analogue
To be Published
5WRR
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BU of 5wrr by Molmil
Crystal structure of Fam20A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Pseudokinase FAM20A
Authors:Zhu, Q.
Deposit date:2016-12-03
Release date:2017-05-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.506 Å)
Cite:Structure of Fam20A reveals a pseudokinase featuring a unique disulfide pattern and inverted ATP-binding
Elife, 6, 2017

 

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