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3FEY
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BU of 3fey by Molmil
Crystal structure of the CBC-importin alpha complex.
Descriptor: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2
Authors:Dias, S.M.G, Ambrosio, A.L.B, Cerione, R.A.
Deposit date:2008-12-01
Release date:2009-08-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The molecular basis for the regulation of the cap-binding complex by the importins.
Nat.Struct.Mol.Biol., 16, 2009
3FEX
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BU of 3fex by Molmil
Crystal structure of the CBC-importin alpha complex.
Descriptor: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2
Authors:Dias, S.M.G, Ambrosio, A.L.B, Cerione, R.A.
Deposit date:2008-12-01
Release date:2009-08-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.549 Å)
Cite:The molecular basis for the regulation of the cap-binding complex by the importins.
Nat.Struct.Mol.Biol., 16, 2009
4JKT
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BU of 4jkt by Molmil
Crystal structure of mouse Glutaminase C, BPTES-bound form
Descriptor: Glutaminase kidney isoform, mitochondrial, N,N'-[sulfanediylbis(ethane-2,1-diyl-1,3,4-thiadiazole-5,2-diyl)]bis(2-phenylacetamide)
Authors:Fornezari, C, Ferreira, A.P.S, Dias, S.M.G, Ambrosio, A.L.B.
Deposit date:2013-03-11
Release date:2013-08-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Active Glutaminase C Self-assembles into a Supratetrameric Oligomer That Can Be Disrupted by an Allosteric Inhibitor.
J.Biol.Chem., 288, 2013
3SUK
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BU of 3suk by Molmil
Crystal structure of cerato-platanin 2 from M. perniciosa (MpCP2)
Descriptor: Cerato-platanin-like protein
Authors:Oliveira, J.F, Barsottini, M.R.O, Zaparoli, G, Machado, L.O, Dias, S.M.G, Pereira, G.A.G, Ambrosio, A.L.B.
Deposit date:2011-07-11
Release date:2012-07-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Functional diversification of cerato-platanins in Moniliophthora perniciosa as seen by differential expression and protein function specialization.
Mol. Plant Microbe Interact., 26, 2013
3SS5
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BU of 3ss5 by Molmil
Crystal structure of mouse Glutaminase C, L-glutamate-bound form
Descriptor: GLUTAMIC ACID, Glutaminase C
Authors:Ambrosio, A.L.B, Dias, S.M.G, Cerione, R.A.
Deposit date:2011-07-07
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
3SUJ
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BU of 3suj by Molmil
Crystal structure of cerato-platanin 1 from M. perniciosa (MpCP1)
Descriptor: ACETATE ION, CHLORIDE ION, Cerato-platanin 1, ...
Authors:Oliveira, J.F, Barsottini, M.R.O, Zaparoli, G, Machado, L.O, Dias, S.M.G, Pereira, G.A.G, Ambrosio, A.L.B.
Deposit date:2011-07-11
Release date:2012-07-11
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Functional diversification of cerato-platanins in Moniliophthora perniciosa as seen by differential expression and protein function specialization.
Mol. Plant Microbe Interact., 26, 2013
3SUM
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BU of 3sum by Molmil
Crystal structure of cerato-platanin 5 from M. perniciosa (MpCP5)
Descriptor: Cerato-platanin-like protein
Authors:Oliveira, J.F, Barsottini, M.R.O, Zaparoli, G, Machado, L.O, Dias, S.M.G, Pereira, G.A.G, Ambrosio, A.L.B.
Deposit date:2011-07-11
Release date:2012-07-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Functional diversification of cerato-platanins in Moniliophthora perniciosa as seen by differential expression and protein function specialization.
Mol. Plant Microbe Interact., 26, 2013
3ST1
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BU of 3st1 by Molmil
Crystal structure of Necrosis and Ethylene inducing Protein 2 from the causal agent of cocoa's Witches Broom disease
Descriptor: Necrosis-and ethylene-inducing protein, SODIUM ION, ZINC ION
Authors:Oliveira, J.F, Zaparoli, G, Barsottini, M.R.O, Ambrosio, A.L.B, Pereira, G.A.G, Dias, S.M.G.
Deposit date:2011-07-08
Release date:2011-11-02
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Crystal Structure of Necrosis- and Ethylene-Inducing Protein 2 from the Causal Agent of Cacao's Witches' Broom Disease Reveals Key Elements for Its Activity.
Biochemistry, 50, 2011
3SUL
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BU of 3sul by Molmil
Crystal structure of cerato-platanin 3 from M. perniciosa (MpCP3)
Descriptor: Cerato-platanin-like protein
Authors:Oliveira, J.F, Barsottini, M.R.O, Zaparoli, G, Machado, L.O, Dias, S.M.G, Pereira, G.A.G, Ambrosio, A.L.B.
Deposit date:2011-07-11
Release date:2012-07-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Functional diversification of cerato-platanins in Moniliophthora perniciosa as seen by differential expression and protein function specialization.
Mol. Plant Microbe Interact., 26, 2013
3SS4
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BU of 3ss4 by Molmil
Crystal structure of mouse Glutaminase C, phosphate-bound form
Descriptor: Glutaminase C, PHOSPHATE ION
Authors:Ambrosio, A.L.B, Dias, S.M.G, Cerione, R.A.
Deposit date:2011-07-07
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
3SS3
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BU of 3ss3 by Molmil
Crystal structure of mouse Glutaminase C, ligand-free form
Descriptor: CHLORIDE ION, Glutaminase C
Authors:Ambrosio, A.L.B, Dias, S.M.G, Cerione, R.A.
Deposit date:2011-07-07
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
2PTW
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BU of 2ptw by Molmil
Crystal Structure of the T. brucei enolase complexed with sulphate, identification of a metal binding site IV
Descriptor: 1,2-ETHANEDIOL, Enolase, SULFATE ION, ...
Authors:Navarro, M.V.A.S, Rigden, D.J, Garratt, R.C, Dias, S.M.G.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
2PTZ
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BU of 2ptz by Molmil
Crystal Structure of the T. brucei enolase complexed with phosphonoacetohydroxamate (PAH), His156-out conformation
Descriptor: 1,2-ETHANEDIOL, Enolase, PHOSPHONOACETOHYDROXAMIC ACID, ...
Authors:Navarro, M.V.A.S, Rigden, D.J, Garratt, R.C, Dias, S.M.G.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
2PU0
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BU of 2pu0 by Molmil
Crystal Structure of the T. brucei enolase complexed with phosphonoacetohydroxamate (PAH), His156-in conformation
Descriptor: 1,2-ETHANEDIOL, Enolase, PHOSPHONOACETOHYDROXAMIC ACID, ...
Authors:Navarro, M.V.A.S, Rigden, D.J, Garratt, R.C, Dias, S.M.G.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
2PTY
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BU of 2pty by Molmil
Crystal Structure of the T. brucei enolase complexed with PEP
Descriptor: 1,2-ETHANEDIOL, Enolase, PHOSPHOENOLPYRUVATE, ...
Authors:Navarro, M.V.A.S, Rigden, D.J, Garratt, R.C, Dias, S.M.G.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
2PTX
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BU of 2ptx by Molmil
Crystal Structure of the T. brucei enolase complexed with sulphate in closed conformation
Descriptor: 1,2-ETHANEDIOL, Enolase, SULFATE ION, ...
Authors:Navarro, M.V.A.S, Rigden, D.J, Garratt, R.C, Dias, S.M.G.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
2PU1
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BU of 2pu1 by Molmil
Crystal Structure of the T. brucei enolase complexed with Fluoro-phosphonoacetohydroxamate (FPAH)
Descriptor: 1,2-ETHANEDIOL, Enolase, ZINC ION, ...
Authors:Navarro, M.V.A.S, Rigden, D.J, Garratt, R.C, Dias, S.M.G.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
3JZB
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BU of 3jzb by Molmil
Crystal Structure of TR-alfa bound to the selective thyromimetic TRIAC
Descriptor: THRA protein, [4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC ACID
Authors:Nascimento, A.S, Dias, S.M.G, Nunes, F.M, Aparicio, R.
Deposit date:2009-09-23
Release date:2009-12-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.007 Å)
Cite:Gaining ligand selectivity in thyroid hormone receptors via entropy.
Proc.Natl.Acad.Sci.USA, 106, 2009
3JZC
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BU of 3jzc by Molmil
Crystal Structure of TR-beta bound to the selective thyromimetic TRIAC
Descriptor: Thyroid hormone receptor beta, [4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC ACID
Authors:Nascimento, A.S, Dias, S.G.M, Nunes, F.M, Aparicio, R.
Deposit date:2009-09-23
Release date:2009-12-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Gaining ligand selectivity in thyroid hormone receptors via entropy.
Proc.Natl.Acad.Sci.USA, 106, 2009
4WN5
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BU of 4wn5 by Molmil
Crystal structure of the C-terminal Per-Arnt-Sim (PASb) of human HIF-3alpha9 bound to 18:1-1-monoacylglycerol
Descriptor: HEXAETHYLENE GLYCOL, Hypoxia-inducible factor 3-alpha, MONOVACCENIN, ...
Authors:Fala, A.M, Oliveira, J.F, Dias, S.M, Ambrosio, A.L.
Deposit date:2014-10-10
Release date:2015-08-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Unsaturated fatty acids as high-affinity ligands of the C-terminal Per-ARNT-Sim domain from the Hypoxia-inducible factor 3 alpha.
Sci Rep, 5, 2015
8EC6
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BU of 8ec6 by Molmil
Cryo-EM structure of the Glutaminase C core filament (fGAC)
Descriptor: Isoform 2 of Glutaminase kidney isoform, mitochondrial, PHOSPHATE ION
Authors:Ambrosio, A.L, Dias, S.M, Quesnay, J.E, Portugal, R.V, Cassago, A, van Heel, M.G, Islam, Z, Rodrigues, C.T.
Deposit date:2022-09-01
Release date:2023-09-20
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Molecular mechanism of glutaminase activation through filamentation and the role of filaments in mitophagy protection.
Nat.Struct.Mol.Biol., 30, 2023
3HZF
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BU of 3hzf by Molmil
Structure of TR-alfa bound to selective thyromimetic GC-1 in C2 space group
Descriptor: Thyroid hormone receptor, alpha isoform 1 variant, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid
Authors:Aparicio, R, Bleicher, L, Polikarpov, I.
Deposit date:2009-06-23
Release date:2009-07-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms.
Bmc Struct.Biol., 8, 2008
3ILZ
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BU of 3ilz by Molmil
Structure of TR-alfa bound to selective thyromimetic GC-1 in P212121 space group
Descriptor: Thyroid hormone receptor, alpha isoform 1 variant, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid
Authors:Aparicio, R, Polikarpov, L, Bleicher, L.
Deposit date:2009-08-07
Release date:2010-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms.
Bmc Struct.Biol., 8, 2008
3IMY
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BU of 3imy by Molmil
Structure of TR-beta bound to selective thyromimetic GC-1
Descriptor: Thyroid hormone receptor beta, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid
Authors:Bleicher, L, Polikarpov, L, Aparicio, R.
Deposit date:2009-08-11
Release date:2009-09-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms.
BMC STRUCT.BIOL., 8, 2008

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