Author results

1BBS
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X-RAY ANALYSES OF PEPTIDE INHIBITOR COMPLEXES DEFINE THE STRUCTURAL BASIS OF SPECIFICITY FOR HUMAN AND MOUSE RENINS
Descriptor:RENIN
Authors:Dhanaraj, V., Blundell, T.L.
Deposit date:1992-05-21
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:X-ray analyses of peptide-inhibitor complexes define the structural basis of specificity for human and mouse renins.
Nature, 357, 1992
1QIB
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CRYSTAL STRUCTURE OF GELATINASE A CATALYTIC DOMAIN
Descriptor:72 kDa type IV collagenase, ZINC ION, CALCIUM ION
Authors:Dhanaraj, V., Williams, M.G., Ye, Q.-Z., Molina, F., Johnson, L.L., Ortwine, D.F., Pavlovsky, A., Rubin, J.R., Skeean, R.W., White, A.D., Humblet, C., Hupe, D.J., Blundell, T.L.
Deposit date:1999-06-11
Release date:1999-11-19
Last modified:2017-05-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:X-ray structure of gelatinase A catalytic domain complexed with a hydroxamate inhibitor
Croatica Chemica Acta, 72, 1999
1BLX
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P19INK4D/CDK6 COMPLEX
Descriptor:CYCLIN-DEPENDENT KINASE 6, P19INK4D, CALCIUM ION
Authors:Brotherton, D.H., Dhanaraj, V., Wick, S., Brizuela, L., Domaille, P.J., Volyanik, E., Xu, X., Parisini, E., Smith, B.O., Archer, S.J., Serrano, M., Brenner, S.L., Blundell, T.L., Laue, E.D.
Deposit date:1998-07-21
Release date:1999-06-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d.
Nature, 395, 1998
1AW8
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PYRUVOYL DEPENDENT ASPARTATE DECARBOXYLASE
Descriptor:L-ASPARTATE-ALPHA-DECARBOXYLASE
Authors:Albert, A., Dhanaraj, V., Genschel, U., Khan, G., Ramjee, M.K., Pulido, R., Sybanda, B.L., von Delf, F., Witty, M., Blundell, T.L., Smith, A.G., Abell, C.
Deposit date:1997-10-12
Release date:1998-04-29
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of aspartate decarboxylase at 2.2 A resolution provides evidence for an ester in protein self-processing.
Nat.Struct.Biol., 5, 1998
1B8Y
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X-RAY STRUCTURE OF HUMAN STROMELYSIN CATALYTIC DOMAIN COMPLEXED WITH NON-PEPTIDE INHIBITORS: IMPLICATIONS FOR INHIBITOR SELECTIVITY
Descriptor:PROTEIN (STROMELYSIN-1), ZINC ION, CALCIUM ION, ...
Authors:Pavlovsky, A.G., Williams, M.G., Ye, Q.-Z., Ortwine, D.F., Purchase II, C.F., White, A.D., Dhanaraj, V., Roth, B.D., Johnson, L.L., Hupe, D., Humblet, C., Blundell, T.L.
Deposit date:1999-02-03
Release date:1999-08-31
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity.
Protein Sci., 8, 1999
1CAQ
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X-RAY STRUCTURE OF HUMAN STROMELYSIN CATALYTIC DOMAIN COMPLEXES WITH NON-PEPTIDE INHIBITORS: IMPLICATION FOR INHIBITOR SELECTIVITY
Descriptor:PROTEIN (STROMELYSIN-1), ZINC ION, CALCIUM ION, ...
Authors:Pavlovsky, A.G., Williams, M.G., Ye, Q.-Z., Ortwine, D.F., Purchase II, C.F., White, A.D., Dhanaraj, V., Roth, B.D., Johnson, L.L., Hupe, D., Humblet, C., Blundell, T.L.
Deposit date:1999-02-23
Release date:1999-07-07
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity.
Protein Sci., 8, 1999
1CIZ
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X-RAY STRUCTURE OF HUMAN STROMELYSIN CATALYTIC DOMAIN COMPLEXES WITH NON-PEPTIDE INHIBITORS: IMPLICATION FOR INHIBITOR SELECTIVITY
Descriptor:PROTEIN (STROMELYSIN-1), ZINC ION, CALCIUM ION, ...
Authors:Pavlovsky, A.G., Williams, M.G., Ye, Q.-Z., Ortwine, D.F., Purchase II, C.F., White, A.D., Dhanaraj, V., Roth, B.D., Johnson, L.L., Hupe, D., Humblet, C., Blundell, T.L.
Deposit date:1999-04-06
Release date:1999-09-01
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity.
Protein Sci., 8, 1999
1CZI
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CHYMOSIN COMPLEX WITH THE INHIBITOR CP-113972
Descriptor:CHYMOSIN, CP-113972 (NORSTATINE-S-METHYL CYSTEINE-IODO-PHENYLALANINE-PROLINE)
Authors:Groves, M.R., Dhanaraj, V., Pitts, J.E., Badasso, M., Hoover, D., Nugent, P., Blundell, T.L.
Deposit date:1997-01-15
Release date:1997-04-01
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A 2.3 A resolution structure of chymosin complexed with a reduced bond inhibitor shows that the active site beta-hairpin flap is rearranged when compared with the native crystal structure.
Protein Eng., 11, 1998
1IHO
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CRYSTAL APO-STRUCTURE OF PANTOTHENATE SYNTHETASE FROM E. COLI
Descriptor:PANTOATE--BETA-ALANINE LIGASE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 1,2-ETHANEDIOL
Authors:von Delft, F., Lewendon, A., Dhanaraj, V., Blundell, T.L., Abell, C., Smith, A.
Deposit date:2001-04-19
Release date:2001-05-30
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The crystal structure of E. coli pantothenate synthetase confirms it as a member of the cytidylyltransferase superfamily.
Structure, 9, 2001
1M3U
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CRYSTAL STRUCTURE OF KETOPANTOATE HYDROXYMETHYLTRANSFERASE COMPLEXED THE PRODUCT KETOPANTOATE
Descriptor:3-methyl-2-oxobutanoate hydroxymethyltransferase, MAGNESIUM ION, KETOPANTOATE
Authors:von Delft, F., Inoue, T., Saldanha, S.A., Ottenhof, H.H., Dhanaraj, V., Witty, M., Abell, C., Smith, A.G., Blundell, T.L.
Deposit date:2002-06-30
Release date:2003-07-22
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of E. coli Ketopantoate Hydroxymethyl Transferase Complexed with Ketopantoate and Mg(2+), Solved by Locating 160 Selenomethionine Sites.
Structure, 11, 2003
1QIA
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CRYSTAL STRUCTURE OF STROMELYSIN CATALYTIC DOMAIN
Descriptor:STROMELYSIN-1, ZINC ION, CALCIUM ION
Authors:Williams, M.G., Ye, Q.-Z., Molina, F., Johnson, L.L., Ortwine, D.F., Pavlovsky, A.G., Rubin, J.R., Skeean, R.W., White, A.D., Blundell, T.L., Humblet, C., Hupe, D.J., Dhanaraj, V.
Deposit date:1999-06-11
Release date:2003-02-11
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity
Protein Sci., 8, 1999
1QIC
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CRYSTAL STRUCTURE OF STROMELYSIN CATALYTIC DOMAIN
Descriptor:PROTEIN (STROMELYSIN-1), ZINC ION, CALCIUM ION
Authors:Williams, M.G., Ye, Q.-Z., Molina, F., Johnson, L.L., Ortwine, D.F., Pavlovsky, A.G., Rubin, J.R., Skeean, R.W., White, A.D., Blundell, T.L., Humblet, C., Hupe, D.J., Dhanaraj, V.
Deposit date:1999-06-11
Release date:2003-02-11
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity
Protein Sci., 8, 1999
1RQF
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STRUCTURE OF CK2 BETA SUBUNIT CRYSTALLIZED IN THE PRESENCE OF A P21WAF1 PEPTIDE
Descriptor:Casein kinase II beta chain, Disordered segment of Cyclin-dependent kinase inhibitor 1, ZINC ION, ...
Authors:Bertrand, L., Sayed, M.F., Pei, X.-Y., Parisini, E., Dhanaraj, V., Bolanos-Garcia, V.M., Allende, J.E., Blundell, T.L.
Deposit date:2003-12-05
Release date:2004-10-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Structure of the regulatory subunit of CK2 in the presence of a p21WAF1 peptide demonstrates flexibility of the acidic loop.
Acta Crystallogr.,Sect.D, 60, 2004
1JAC
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A NOVEL MODE OF CARBOHYDRATE RECOGNITION IN JACALIN, A MORACEAE PLANT LECTIN WITH A BETA-PRISM
Descriptor:JACALIN, ALPHA-METHYL-D-GALACTOSIDE
Authors:Sankaranarayanan, R., Sekar, K., Banerjee, R., Sharma, V., Surolia, A., Vijayan, M.
Deposit date:1996-05-22
Release date:1997-06-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:A novel mode of carbohydrate recognition in jacalin, a Moraceae plant lectin with a beta-prism fold.
Nat.Struct.Biol., 3, 1996
1SMR
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THE 3-D STRUCTURE OF MOUSE SUBMAXILLARY RENIN COMPLEXED WITH A DECAPEPTIDE INHIBITOR CH-66 BASED ON THE 4-16 FRAGMENT OF RAT ANGIOTENSINOGEN
Descriptor:RENIN, INHIBITOR CH-66
Authors:Dealwis, C.G., Blundell, T.L.
Deposit date:1992-03-11
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray analysis at 2.0 A resolution of mouse submaxillary renin complexed with a decapeptide inhibitor CH-66, based on the 4-16 fragment of rat angiotensinogen.
J.Mol.Biol., 236, 1994
1ZS0
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN MMP-8 AND A PHOSPHONATE INHIBITOR (S-ENANTIOMER)
Descriptor:Neutrophil collagenase, CALCIUM ION, ZINC ION, ...
Authors:Pochetti, G., Gavuzzo, E., Campestre, C., Agamennone, M., Tortorella, P., Consalvi, V., Gallina, C., Hiller, O., Tschesche, H., Tucker, P.A., Mazza, F.
Deposit date:2005-05-23
Release date:2006-05-02
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Structural insight into the stereoselective inhibition of MMP-8 by enantiomeric sulfonamide phosphonates.
J.Med.Chem., 49, 2006
1ZVX
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN MMP-8 AND A PHOSPHONATE INHIBITOR (R-ENANTIOMER)
Descriptor:Neutrophil collagenase, CALCIUM ION, ZINC ION, ...
Authors:Pochetti, G., Gavuzzo, E., Campestre, C., Agamennone, M., Tortorella, P., Consalvi, V., Gallina, C., Hiller, O., Tschesche, H., Tucker, P.A., Mazza, F.
Deposit date:2005-06-03
Release date:2006-05-16
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structural insight into the stereoselective inhibition of MMP-8 by enantiomeric sulfonamide phosphonates.
J.Med.Chem., 49, 2006
1BZW
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PEANUT LECTIN COMPLEXED WITH C-LACTOSE
Descriptor:PROTEIN (PEANUT LECTIN), BETA-D-GALACTOSE, ALPHA-D-GLUCOSE, ...
Authors:Ravishankar, R., Surolia, A., Vijayan, M., Lim, S., Kishi, Y.
Deposit date:1998-11-05
Release date:1998-11-11
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Preferred Conformation of C-Lactose at the Free and Peanut Lectin Bound States
J.Am.Chem.Soc., 120, 1998
1CIW
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PEANUT LECTIN COMPLEXED WITH N-ACETYLLACTOSAMINE
Descriptor:PROTEIN (PEANUT LECTIN), BETA-D-GALACTOSE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Ravishankar, R., Suguna, K., Surolia, A., Vijayan, M.
Deposit date:1999-04-06
Release date:1999-07-27
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structures of the complexes of peanut lectin with methyl-beta-galactose and N-acetyllactosamine and a comparative study of carbohydrate binding in Gal/GalNAc-specific legume lectins.
Acta Crystallogr.,Sect.D, 55, 1999
1CQ9
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PEANUT LECTIN-TRICLINIC FORM
Descriptor:PROTEIN (PEANUT LECTIN), CALCIUM ION, MANGANESE (II) ION
Authors:Ravishankar, R., Suguna, K., Surolia, A., Vijayan, M.
Deposit date:1999-08-06
Release date:2002-05-01
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structures of the peanut lectin-lactose complex at acidic pH: retention of unusual quaternary structure, empty and carbohydrate bound combining sites, molecular mimicry and crystal packing directed by interactions at the combining site.
Proteins, 43, 2001
1CR7
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PEANUT LECTIN-LACTOSE COMPLEX MONOCLINIC FORM
Descriptor:LECTIN, BETA-D-GALACTOSE, ALPHA-D-GLUCOSE, ...
Authors:Ravishankar, R., Suguna, K., Surolia, A., Vijayan, M.
Deposit date:1999-08-14
Release date:2001-04-21
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of the peanut lectin-lactose complex at acidic pH: retention of unusual quaternary structure, empty and carbohydrate bound combining sites, molecular mimicry and crystal packing directed by interactions at the combining site.
Proteins, 43, 2001
1QF3
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PEANUT LECTIN COMPLEXED WITH METHYL-BETA-GALACTOSE
Descriptor:PROTEIN (PEANUT LECTIN), METHYL-BETA-GALACTOSE, CALCIUM ION, ...
Authors:Ravishankar, R., Suguna, K., Surolia, A., Vijayan, M.
Deposit date:1999-04-06
Release date:1999-07-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of the complexes of peanut lectin with methyl-beta-galactose and N-acetyllactosamine and a comparative study of carbohydrate binding in Gal/GalNAc-specific legume lectins.
Acta Crystallogr.,Sect.D, 55, 1999
2DH1
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CRYSTAL STRUCTURE OF PEANUT LECTIN LACTOSE-AZOBENZENE-4,4'-DICARBOXYLIC ACID-LACTOSE COMPLEX
Descriptor:Galactose-binding lectin
Authors:Natchiar, S.K., Srinivas, O., Nivedita, M., Sagarika, D., Jayaraman, N., Surolia, A., Vijayan, M.
Deposit date:2006-03-17
Release date:2006-08-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (7.65 Å)
Cite:Multivalency in lectins - A crystallographic, modelling and light-scattering study involving peanut lectin and a bivalent ligand
Curr.Sci., 90, 2006
2DV9
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CRYSTAL STRUCTURE OF PEANUT LECTIN GAL-BETA-1,3-GAL COMPLEX
Descriptor:Galactose-binding lectin, BETA-D-GALACTOSE, CALCIUM ION, ...
Authors:Natchiar, S.K., Srinivas, O., Mitra, N., Surolia, A., Jayaraman, N., Vijayan, M.
Deposit date:2006-07-30
Release date:2006-11-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structural studies on peanut lectin complexed with disaccharides involving different linkages: further insights into the structure and interactions of the lectin
ACTA CRYSTALLOGR.,SECT.D, 62, 2006
2DVA
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CRYSTAL STRUCTURE OF PEANUT LECTIN GAL-BETA-1,3-GALNAC-ALPHA-O-ME (METHYL-T-ANTIGEN) COMPLEX
Descriptor:Galactose-binding lectin, BETA-D-GALACTOSE, ALPHA-METHYL-N-ACETYL-D-GALACTOSAMINE, ...
Authors:Natchiar, S.K., Srinivas, O., Mitra, N., Surolia, A., Jayaraman, N., Vijayan, M.
Deposit date:2006-07-30
Release date:2006-11-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural studies on peanut lectin complexed with disaccharides involving different linkages: further insights into the structure and interactions of the lectin
ACTA CRYSTALLOGR.,SECT.D, 62, 2006
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