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1BBS
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X-RAY ANALYSES OF PEPTIDE INHIBITOR COMPLEXES DEFINE THE STRUCTURAL BASIS OF SPECIFICITY FOR HUMAN AND MOUSE RENINS
分子名称:RENIN
著者Dhanaraj, V., Blundell, T.L.
登録日1992-05-21
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献X-ray analyses of peptide-inhibitor complexes define the structural basis of specificity for human and mouse renins.
Nature, 357, 1992
1QIB
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CRYSTAL STRUCTURE OF GELATINASE A CATALYTIC DOMAIN
分子名称:72 kDa type IV collagenase, ZINC ION, CALCIUM ION
著者Dhanaraj, V., Williams, M.G., Ye, Q.-Z., Molina, F., Johnson, L.L., Ortwine, D.F., Pavlovsky, A., Rubin, J.R., Skeean, R.W., White, A.D., Humblet, C., Hupe, D.J., Blundell, T.L.
登録日1999-06-11
公開日1999-11-19
最終更新日2017-05-31
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献X-ray structure of gelatinase A catalytic domain complexed with a hydroxamate inhibitor
Croatica Chemica Acta, 72, 1999
1BLX
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P19INK4D/CDK6 COMPLEX
分子名称:CYCLIN-DEPENDENT KINASE 6, P19INK4D, CALCIUM ION
著者Brotherton, D.H., Dhanaraj, V., Wick, S., Brizuela, L., Domaille, P.J., Volyanik, E., Xu, X., Parisini, E., Smith, B.O., Archer, S.J., Serrano, M., Brenner, S.L., Blundell, T.L., Laue, E.D.
登録日1998-07-21
公開日1999-06-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d.
Nature, 395, 1998
1AW8
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PYRUVOYL DEPENDENT ASPARTATE DECARBOXYLASE
分子名称:L-ASPARTATE-ALPHA-DECARBOXYLASE
著者Albert, A., Dhanaraj, V., Genschel, U., Khan, G., Ramjee, M.K., Pulido, R., Sybanda, B.L., von Delf, F., Witty, M., Blundell, T.L., Smith, A.G., Abell, C.
登録日1997-10-12
公開日1998-04-29
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of aspartate decarboxylase at 2.2 A resolution provides evidence for an ester in protein self-processing.
Nat.Struct.Biol., 5, 1998
1B8Y
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X-RAY STRUCTURE OF HUMAN STROMELYSIN CATALYTIC DOMAIN COMPLEXED WITH NON-PEPTIDE INHIBITORS: IMPLICATIONS FOR INHIBITOR SELECTIVITY
分子名称:PROTEIN (STROMELYSIN-1), ZINC ION, CALCIUM ION, ...
著者Pavlovsky, A.G., Williams, M.G., Ye, Q.-Z., Ortwine, D.F., Purchase II, C.F., White, A.D., Dhanaraj, V., Roth, B.D., Johnson, L.L., Hupe, D., Humblet, C., Blundell, T.L.
登録日1999-02-03
公開日1999-08-31
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity.
Protein Sci., 8, 1999
1CAQ
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X-RAY STRUCTURE OF HUMAN STROMELYSIN CATALYTIC DOMAIN COMPLEXES WITH NON-PEPTIDE INHIBITORS: IMPLICATION FOR INHIBITOR SELECTIVITY
分子名称:PROTEIN (STROMELYSIN-1), ZINC ION, CALCIUM ION, ...
著者Pavlovsky, A.G., Williams, M.G., Ye, Q.-Z., Ortwine, D.F., Purchase II, C.F., White, A.D., Dhanaraj, V., Roth, B.D., Johnson, L.L., Hupe, D., Humblet, C., Blundell, T.L.
登録日1999-02-23
公開日1999-07-07
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity.
Protein Sci., 8, 1999
1CIZ
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X-RAY STRUCTURE OF HUMAN STROMELYSIN CATALYTIC DOMAIN COMPLEXES WITH NON-PEPTIDE INHIBITORS: IMPLICATION FOR INHIBITOR SELECTIVITY
分子名称:PROTEIN (STROMELYSIN-1), ZINC ION, CALCIUM ION, ...
著者Pavlovsky, A.G., Williams, M.G., Ye, Q.-Z., Ortwine, D.F., Purchase II, C.F., White, A.D., Dhanaraj, V., Roth, B.D., Johnson, L.L., Hupe, D., Humblet, C., Blundell, T.L.
登録日1999-04-06
公開日1999-09-01
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity.
Protein Sci., 8, 1999
1CZI
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CHYMOSIN COMPLEX WITH THE INHIBITOR CP-113972
分子名称:CHYMOSIN, CP-113972 (NORSTATINE-S-METHYL CYSTEINE-IODO-PHENYLALANINE-PROLINE)
著者Groves, M.R., Dhanaraj, V., Pitts, J.E., Badasso, M., Hoover, D., Nugent, P., Blundell, T.L.
登録日1997-01-15
公開日1997-04-01
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A 2.3 A resolution structure of chymosin complexed with a reduced bond inhibitor shows that the active site beta-hairpin flap is rearranged when compared with the native crystal structure.
Protein Eng., 11, 1998
1IHO
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CRYSTAL APO-STRUCTURE OF PANTOTHENATE SYNTHETASE FROM E. COLI
分子名称:PANTOATE--BETA-ALANINE LIGASE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 1,2-ETHANEDIOL
著者von Delft, F., Lewendon, A., Dhanaraj, V., Blundell, T.L., Abell, C., Smith, A.
登録日2001-04-19
公開日2001-05-30
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The crystal structure of E. coli pantothenate synthetase confirms it as a member of the cytidylyltransferase superfamily.
Structure, 9, 2001
1M3U
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CRYSTAL STRUCTURE OF KETOPANTOATE HYDROXYMETHYLTRANSFERASE COMPLEXED THE PRODUCT KETOPANTOATE
分子名称:3-methyl-2-oxobutanoate hydroxymethyltransferase, MAGNESIUM ION, KETOPANTOATE
著者von Delft, F., Inoue, T., Saldanha, S.A., Ottenhof, H.H., Dhanaraj, V., Witty, M., Abell, C., Smith, A.G., Blundell, T.L.
登録日2002-06-30
公開日2003-07-22
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of E. coli Ketopantoate Hydroxymethyl Transferase Complexed with Ketopantoate and Mg(2+), Solved by Locating 160 Selenomethionine Sites.
Structure, 11, 2003
1QIA
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CRYSTAL STRUCTURE OF STROMELYSIN CATALYTIC DOMAIN
分子名称:STROMELYSIN-1, ZINC ION, CALCIUM ION
著者Williams, M.G., Ye, Q.-Z., Molina, F., Johnson, L.L., Ortwine, D.F., Pavlovsky, A.G., Rubin, J.R., Skeean, R.W., White, A.D., Blundell, T.L., Humblet, C., Hupe, D.J., Dhanaraj, V.
登録日1999-06-11
公開日2003-02-11
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity
Protein Sci., 8, 1999
1QIC
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CRYSTAL STRUCTURE OF STROMELYSIN CATALYTIC DOMAIN
分子名称:PROTEIN (STROMELYSIN-1), ZINC ION, CALCIUM ION
著者Williams, M.G., Ye, Q.-Z., Molina, F., Johnson, L.L., Ortwine, D.F., Pavlovsky, A.G., Rubin, J.R., Skeean, R.W., White, A.D., Blundell, T.L., Humblet, C., Hupe, D.J., Dhanaraj, V.
登録日1999-06-11
公開日2003-02-11
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity
Protein Sci., 8, 1999
1RQF
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STRUCTURE OF CK2 BETA SUBUNIT CRYSTALLIZED IN THE PRESENCE OF A P21WAF1 PEPTIDE
分子名称:Casein kinase II beta chain, Disordered segment of Cyclin-dependent kinase inhibitor 1, ZINC ION, ...
著者Bertrand, L., Sayed, M.F., Pei, X.-Y., Parisini, E., Dhanaraj, V., Bolanos-Garcia, V.M., Allende, J.E., Blundell, T.L.
登録日2003-12-05
公開日2004-10-05
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Structure of the regulatory subunit of CK2 in the presence of a p21WAF1 peptide demonstrates flexibility of the acidic loop.
Acta Crystallogr.,Sect.D, 60, 2004
1JAC
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A NOVEL MODE OF CARBOHYDRATE RECOGNITION IN JACALIN, A MORACEAE PLANT LECTIN WITH A BETA-PRISM
分子名称:JACALIN, ALPHA-METHYL-D-GALACTOSIDE
著者Sankaranarayanan, R., Sekar, K., Banerjee, R., Sharma, V., Surolia, A., Vijayan, M.
登録日1996-05-22
公開日1997-06-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献A novel mode of carbohydrate recognition in jacalin, a Moraceae plant lectin with a beta-prism fold.
Nat.Struct.Biol., 3, 1996
1SMR
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THE 3-D STRUCTURE OF MOUSE SUBMAXILLARY RENIN COMPLEXED WITH A DECAPEPTIDE INHIBITOR CH-66 BASED ON THE 4-16 FRAGMENT OF RAT ANGIOTENSINOGEN
分子名称:RENIN, INHIBITOR CH-66
著者Dealwis, C.G., Blundell, T.L.
登録日1992-03-11
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-ray analysis at 2.0 A resolution of mouse submaxillary renin complexed with a decapeptide inhibitor CH-66, based on the 4-16 fragment of rat angiotensinogen.
J.Mol.Biol., 236, 1994
1ZS0
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN MMP-8 AND A PHOSPHONATE INHIBITOR (S-ENANTIOMER)
分子名称:Neutrophil collagenase, CALCIUM ION, ZINC ION, ...
著者Pochetti, G., Gavuzzo, E., Campestre, C., Agamennone, M., Tortorella, P., Consalvi, V., Gallina, C., Hiller, O., Tschesche, H., Tucker, P.A., Mazza, F.
登録日2005-05-23
公開日2006-05-02
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Structural insight into the stereoselective inhibition of MMP-8 by enantiomeric sulfonamide phosphonates.
J.Med.Chem., 49, 2006
1ZVX
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN MMP-8 AND A PHOSPHONATE INHIBITOR (R-ENANTIOMER)
分子名称:Neutrophil collagenase, CALCIUM ION, ZINC ION, ...
著者Pochetti, G., Gavuzzo, E., Campestre, C., Agamennone, M., Tortorella, P., Consalvi, V., Gallina, C., Hiller, O., Tschesche, H., Tucker, P.A., Mazza, F.
登録日2005-06-03
公開日2006-05-16
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structural insight into the stereoselective inhibition of MMP-8 by enantiomeric sulfonamide phosphonates.
J.Med.Chem., 49, 2006
1BZW
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PEANUT LECTIN COMPLEXED WITH C-LACTOSE
分子名称:PROTEIN (PEANUT LECTIN), BETA-D-GALACTOSE, ALPHA-D-GLUCOSE, ...
著者Ravishankar, R., Surolia, A., Vijayan, M., Lim, S., Kishi, Y.
登録日1998-11-05
公開日1998-11-11
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Preferred Conformation of C-Lactose at the Free and Peanut Lectin Bound States
J.Am.Chem.Soc., 120, 1998
1CIW
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PEANUT LECTIN COMPLEXED WITH N-ACETYLLACTOSAMINE
分子名称:PROTEIN (PEANUT LECTIN), BETA-D-GALACTOSE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
著者Ravishankar, R., Suguna, K., Surolia, A., Vijayan, M.
登録日1999-04-06
公開日1999-07-27
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structures of the complexes of peanut lectin with methyl-beta-galactose and N-acetyllactosamine and a comparative study of carbohydrate binding in Gal/GalNAc-specific legume lectins.
Acta Crystallogr.,Sect.D, 55, 1999
1CQ9
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PEANUT LECTIN-TRICLINIC FORM
分子名称:PROTEIN (PEANUT LECTIN), CALCIUM ION, MANGANESE (II) ION
著者Ravishankar, R., Suguna, K., Surolia, A., Vijayan, M.
登録日1999-08-06
公開日2002-05-01
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystal structures of the peanut lectin-lactose complex at acidic pH: retention of unusual quaternary structure, empty and carbohydrate bound combining sites, molecular mimicry and crystal packing directed by interactions at the combining site.
Proteins, 43, 2001
1CR7
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PEANUT LECTIN-LACTOSE COMPLEX MONOCLINIC FORM
分子名称:LECTIN, BETA-D-GALACTOSE, ALPHA-D-GLUCOSE, ...
著者Ravishankar, R., Suguna, K., Surolia, A., Vijayan, M.
登録日1999-08-14
公開日2001-04-21
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structures of the peanut lectin-lactose complex at acidic pH: retention of unusual quaternary structure, empty and carbohydrate bound combining sites, molecular mimicry and crystal packing directed by interactions at the combining site.
Proteins, 43, 2001
1QF3
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PEANUT LECTIN COMPLEXED WITH METHYL-BETA-GALACTOSE
分子名称:PROTEIN (PEANUT LECTIN), METHYL-BETA-GALACTOSE, CALCIUM ION, ...
著者Ravishankar, R., Suguna, K., Surolia, A., Vijayan, M.
登録日1999-04-06
公開日1999-07-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of the complexes of peanut lectin with methyl-beta-galactose and N-acetyllactosamine and a comparative study of carbohydrate binding in Gal/GalNAc-specific legume lectins.
Acta Crystallogr.,Sect.D, 55, 1999
2DH1
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CRYSTAL STRUCTURE OF PEANUT LECTIN LACTOSE-AZOBENZENE-4,4'-DICARBOXYLIC ACID-LACTOSE COMPLEX
分子名称:Galactose-binding lectin
著者Natchiar, S.K., Srinivas, O., Nivedita, M., Sagarika, D., Jayaraman, N., Surolia, A., Vijayan, M.
登録日2006-03-17
公開日2006-08-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (7.65 Å)
主引用文献Multivalency in lectins - A crystallographic, modelling and light-scattering study involving peanut lectin and a bivalent ligand
Curr.Sci., 90, 2006
2DV9
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CRYSTAL STRUCTURE OF PEANUT LECTIN GAL-BETA-1,3-GAL COMPLEX
分子名称:Galactose-binding lectin, BETA-D-GALACTOSE, CALCIUM ION, ...
著者Natchiar, S.K., Srinivas, O., Mitra, N., Surolia, A., Jayaraman, N., Vijayan, M.
登録日2006-07-30
公開日2006-11-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Structural studies on peanut lectin complexed with disaccharides involving different linkages: further insights into the structure and interactions of the lectin
ACTA CRYSTALLOGR.,SECT.D, 62, 2006
2DVA
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CRYSTAL STRUCTURE OF PEANUT LECTIN GAL-BETA-1,3-GALNAC-ALPHA-O-ME (METHYL-T-ANTIGEN) COMPLEX
分子名称:Galactose-binding lectin, BETA-D-GALACTOSE, ALPHA-METHYL-N-ACETYL-D-GALACTOSAMINE, ...
著者Natchiar, S.K., Srinivas, O., Mitra, N., Surolia, A., Jayaraman, N., Vijayan, M.
登録日2006-07-30
公開日2006-11-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural studies on peanut lectin complexed with disaccharides involving different linkages: further insights into the structure and interactions of the lectin
ACTA CRYSTALLOGR.,SECT.D, 62, 2006
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