Author results

1WAN
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DNA DTA TRIPLEX, NMR, 7 STRUCTURES
Descriptor:DNA (5'-D(*AP*GP*AP*TP*AP*GP*AP*AP*CP*CP*CP*CP*TP*TP*CP*TP*AP*TP*CP*TP*TP*AP*TP*AP*TP*CP*TP*(D3)P*TP*CP*TP*T)-3')
Authors:Wang, E., Koshlap, K.M., Gillespie, P., Dervan, P.B., Feigon, J.
Deposit date:1996-01-14
Release date:1996-07-11
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a pyrimidine-purine-pyrimidine triplex containing the sequence-specific intercalating non-natural base D3.
J.Mol.Biol., 257, 1996
1CVX
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CRYSTAL STRUCTURE OF POLYAMIDE DIMER (IMPYHPPYBETADP)2 BOUND TO B-DNA DECAMER CCAGATCTGG
Descriptor:5'-D(*CP*CP*AP*GP*AP*TP*CP*TP*GP*G)-3', HYDROXYPYRROLE-IMIDAZOLE-PYRROLE POLYAMIDE
Authors:Kielkopf, C.L., Bremer, R.E., White, S., Baird, E.E., Dervan, P.B., Rees, D.C.
Deposit date:1999-08-24
Release date:2000-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Structural effects of DNA sequence on T.A recognition by hydroxypyrrole/pyrrole pairs in the minor groove.
J.Mol.Biol., 295, 2000
1CVY
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CRYSTAL STRUCTURE OF POLYAMIDE DIMER (IMPYPYPYBETADP)2 BOUND TO CCAGATCTGG
Descriptor:5'-D(*CP*CP*AP*GP*AP*TP*CP*TP*GP*G)-3', IMIDAZOLE-PYRROLE POLYAMIDE
Authors:Kielkopf, C.L., Bremer, R.E., White, S., Baird, E.E., Dervan, P.B., Rees, D.C.
Deposit date:1999-08-24
Release date:2000-01-15
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural effects of DNA sequence on T.A recognition by hydroxypyrrole/pyrrole pairs in the minor groove.
J.Mol.Biol., 295, 2000
1LEJ
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NMR STRUCTURE OF A 1:1 COMPLEX OF POLYAMIDE (IM-PY-BETA-IM-BETA-IM-PY-BETA-DP) WITH THE TRIDECAMER DNA DUPLEX 5'-CCAAAGAGAAGCG-3'
Descriptor:5'-D(*CP*CP*AP*AP*AP*GP*AP*GP*AP*AP*GP*CP*G)-3', 5'-D(*CP*GP*CP*TP*TP*CP*TP*CP*TP*TP*TP*GP*G)-3', IMIDAZOLE-PYRROLE-BETA ALANINE-IMIDAZOLE-BETA ALANINE-IMIDAZOLE-PYRROLE-BETA ALANINE-DIMETHYLAMINO PROPYLAMIDE
Authors:Urbach, A.R., Love, J.J., Ross, S.A., Dervan, P.B.
Deposit date:2002-04-09
Release date:2002-05-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of a beta-alanine-linked polyamide bound to a full helical turn of purine tract DNA in the 1:1 motif.
J.Mol.Biol., 320, 2002
1M18
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LIGAND BINDING ALTERS THE STRUCTURE AND DYNAMICS OF NUCLEOSOMAL DNA
Descriptor:Palindromic 146 Base Pair DNA Fragment, Histone H3.2, Histone H4, ...
Authors:Suto, R.K., Edayathumangalam, R.S., White, C.L., Melander, C., Gottesfeld, J.M., Dervan, P.B., Luger, K.
Deposit date:2002-06-18
Release date:2003-02-18
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal Structures of Nucleosome Core Particles in Complex with Minor Groove DNA-binding Ligands
J.Mol.Biol., 326, 2003
1M19
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LIGAND BINDING ALTERS THE STRUCTURE AND DYNAMICS OF NUCLEOSOMAL DNA
Descriptor:Palindromic 146 Base Pair DNA Fragment, Histone H3.2, Histone H4, ...
Authors:Suto, R.K., Edayathumangalam, R.S., White, C.L., Melander, C., Gottesfeld, J.M., Dervan, P.B., Luger, K.
Deposit date:2002-06-18
Release date:2003-02-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures of Nucleosome Core Particles in Complex with Minor Groove DNA-binding Ligands
J.Mol.Biol., 326, 2003
1M1A
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LIGAND BINDING ALTERS THE STRUCTURE AND DYNAMICS OF NUCLEOSOMAL DNA
Descriptor:Palindromic 146 Base Pair DNA Fragment, Histone H3.2, Histone H4, ...
Authors:Suto, R.K., Edayathumangalam, R.S., White, C.L., Melander, C., Gottesfeld, J.M., Dervan, P.B., Luger, K.
Deposit date:2002-06-18
Release date:2003-02-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal Structures of Nucleosome Core Particles in Complex with Minor Groove DNA-binding Ligands
J.MOL.BIOL., 326, 2003
1PQQ
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NMR STRUCTURE OF A CYCLIC POLYAMIDE-DNA COMPLEX
Descriptor:5'-D(*CP*GP*CP*TP*AP*AP*CP*AP*GP*GP*C)-3', 5'-D(*GP*CP*CP*TP*GP*TP*TP*AP*GP*CP*G)-3', 45-(3-AMINOPROPYL)-5,11,22,28,34-PENTAMETHYL-3,9,15,20,26,32,38,43-OCTAOXO-2,5,8,14,19,22,25,28,31,34,37,42,45,48-TETRADECAAZA-11-AZONIAHEPTACYCLO[42.2.1.1~4,7~.1~10,13~.1~21,24~.1~27,30~.1~33,36~]DOPENTACONTA-1(46),4(52),6,10(51),12,21(50),23,27(49),29,33(48),35,44(47)-DODECAENE
Authors:Zhang, Q., Dwyer, T.J., Tsui, V., Case, D.A., Cho, J., Dervan, P.B., Wemmer, D.E.
Deposit date:2003-06-18
Release date:2004-06-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR Structure of a Cyclic Polyamide-DNA Complex.
J.Am.Chem.Soc., 126, 2004
1S32
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MOLECULAR RECOGNITION OF THE NUCLEOSOMAL 'SUPERGROOVE'
Descriptor:palindromic alpha-satellite 146 bp DNA fragment, histone H3, Histone H4, ...
Authors:Edayathumangalam, R.S., Weyermann, P., Gottesfeld, J.M., Dervan, P.B., Luger, K.
Deposit date:2004-01-12
Release date:2004-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Molecular Recognition of the Nucleosomal 'Supergroove'
Proc.Natl.Acad.Sci.USA, 101, 2004
365D
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STRUCTURAL BASIS FOR G C RECOGNITION IN THE DNA MINOR GROOVE
Descriptor:DNA (5'-D(*CP*CP*AP*GP*GP*(CBR)P*CP*TP*GP*G)-3'), IMIDAZOLE-PYRROLE POLYAMIDE
Authors:Kielkopf, C.L., Baird, E.E., Dervan, P.B., Rees, D.C.
Deposit date:1997-12-17
Release date:1998-02-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for G.C recognition in the DNA minor groove.
Nat.Struct.Biol., 5, 1998
3I5E
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ALLOSTERIC MODULATION OF DNA BY SMALL MOLECULES
Descriptor:5'-D(*CP*CP*AP*GP*GP*CP*CP*TP*GP*G)-3', CALCIUM ION
Authors:Chenoweth, D.M., Dervan, P.B.
Deposit date:2009-07-05
Release date:2009-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (0.98 Å)
Cite:Allosteric modulation of DNA by small molecules
Proc.Natl.Acad.Sci.USA, 106, 2009
3I5L
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ALLOSTERIC MODULATION OF DNA BY SMALL MOLECULES
Descriptor:5'-D(*CP*CP*AP*GP*GP*(C38)P*CP*TP*GP*G)-3', CALCIUM ION, (22R,51R)-22,51-diamino-5,11,17,28,34,40,46,57-octamethyl-2,5,8,11,14,17,20,25,28,31,34,37,40,43,46,49,54,57,60,61,64,65-docosaazanonacyclo[54.2.1.1~4,7~.1~10,13~.1~16,19~.1~27,30~.1~33,36~.1~39,42~.1~45,48~]hexahexaconta-1(58),4(66),6,10(65),12,16(64),18,27(63),29,33(62),35,39(61),41,45(60),47,56(59)-hexadecaene-3,9,15,21,26,32,38,44,50,55-decone
Authors:Chenoweth, D.M., Dervan, P.B.
Deposit date:2009-07-05
Release date:2009-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:Allosteric modulation of DNA by small molecules
Proc.Natl.Acad.Sci.USA, 106, 2009
408D
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STRUCTURAL BASIS FOR RECOGNITION OF A-T AND T-A BASE PAIRS IN THE MINOR GROOVE OF B-DNA
Descriptor:DNA (5'-D(*CP*CP*AP*GP*TP*AP*CP*TP*GP*G)-3'), IMIDAZOLE-PYRROLE POLYAMIDE
Authors:Kielkopf, C.L., White, S., Szewczyk, J.W., Turner, J.M., Baird, E.E., Dervan, P.B., Rees, D.C.
Deposit date:1998-06-24
Release date:1998-10-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A structural basis for recognition of A.T and T.A base pairs in the minor groove of B-DNA.
Science, 282, 1998
8DRH
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HIGH RESOLUTION NMR STRUCTURE OF THE D(GCGTCAGG)R(CCUGACGC) HYBRID, MINIMIZED AVERAGE STRUCTURE
Descriptor:DNA (5'-D(*GP*CP*GP*TP*CP*AP*GP*G)-3'), RNA (5'-R(*CP*CP*UP*GP*AP*CP*GP*C)-3')
Authors:Bachelin, M., Hessler, G., Kurz, G., Hacia, J.G., Dervan, P.B., Kessler, H.
Deposit date:1997-10-13
Release date:1998-05-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of a Stereoregular Phosphorothioate DNA/RNA Duplex
Nat.Struct.Biol., 5, 1998
8PSH
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HIGH RESOLUTION NMR STRUCTURE OF THE STEREOREGULAR (ALL-RP)-PHOSPHOROTHIOATE-DNA/RNA HYBRID D (G*PS*C*PS*G*PS*T*PS*C*PS*A*PS*G*PS*G)R(CCUGACGC), MINIMIZED AVERAGE STRUCTURE
Descriptor:DNA (5'-D(*DGP*(SC)P*(GS)P*(PST)P*(SC)P*(AS)P*(GS)P*(GS))-3'), RNA (5'-R(*CP*CP*UP*GP*AP*CP*GP*C)-3')
Authors:Bachelin, M., Hessler, G., Kurz, G., Hacia, J.G., Dervan, P.B., Kessler, H.
Deposit date:1997-10-13
Release date:1998-05-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of a Stereoregular Phosphorothioate DNA/RNA Duplex
Nat.Struct.Biol., 5, 1998
1GN7
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NMR STRUCTURE OF AN INTRAMOLECULAR DNA TRIPLEX CONTAINING AN N7-GLYCOSYLATED GUANINE, 8 STRUCTURES
Descriptor:DNA (5'-D (*AP*GP*AP*GP*AP*GP*AP*AP*CP*CP*CP*CP*TP*TP*CP*TP*CP*TP* CP*TP*TP*AP*TP*AP*TP*CP*TP*GN7*TP*CP*TP*T)-3')
Authors:Schultze, P., Koshlap, K.M., Feigon, J.
Deposit date:1996-11-22
Release date:1997-05-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of an intramolecular DNA triplex containing an N7-glycosylated guanine which mimics a protonated cytosine.
Biochemistry, 36, 1997
3OMJ
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STRUCTURAL BASIS FOR CYCLIC PY-IM POLYAMIDE ALLOSTERIC INHIBITION OF NUCLEAR RECEPTOR BINDING
Descriptor:5'-D(*CP*(C38)P*AP*GP*TP*AP*CP*TP*GP*G)-3', CALCIUM ION, (23R,52R)-23,52-diamino-5,11,17,28,34,40,46,57-octamethyl-2,5,8,11,14,17,20,25,28,31,34,37,40,43,46,49,54,57,60,64-icosaazanonacyclo[54.2.1.1~4,7~.1~10,13~.1~16,19~.1~27,30~.1~33,36~.1~39,42~.1~45,48~]hexahexaconta-1(58),4(66),6,10(65),12,16(64),18,27(63),29,33(62),35,39(61),41,45(60),47,56(59)-hexadecaene-3,9,15,21,26,32,38,44,50,55-decone
Authors:Chenoweth, D.M.
Deposit date:2010-08-27
Release date:2010-09-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Structural basis for cyclic py-im polyamide allosteric inhibition of nuclear receptor binding.
J.Am.Chem.Soc., 132, 2010
407D
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STRUCTURAL BASIS FOR RECOGNITION OF A-T AND T-A BASE PAIRS IN THE MINOR GROOVE OF B-DNA
Descriptor:DNA (5'-D(*CP*CP*AP*GP*TP*AP*CP*TP*GP*G)-3'), ~{N}-[5-[[5-[[5-[[3-[3-(dimethylamino)propylamino]-3-oxidanylidene-propyl]carbamoyl]-1-methyl-pyrrol-3-yl]carbamoyl]-1-methyl-pyrrol-3-yl]carbamoyl]-1-methyl-4-oxidanyl-pyrrol-3-yl]-1-methyl-imidazole-2-carboxamide, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Rees, D.C.
Deposit date:1998-06-24
Release date:1998-10-19
Last modified:2018-09-26
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A structural basis for recognition of A.T and T.A base pairs in the minor groove of B-DNA.
Science, 282, 1998
4HT4
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MOLECULAR BASIS OF VANCOMYCIN RESISTANCE TRANSFER IN STAPHYLOCOCCUS AUREUS
Descriptor:Nicking enzyme, DNA (28-MER), NICKEL (II) ION, ...
Authors:Edwards, J.S.
Deposit date:2012-10-31
Release date:2013-01-30
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.907 Å)
Cite:Molecular basis of antibiotic multiresistance transfer in Staphylococcus aureus.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HTE
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF NICKING ENZYME FROM STAPHYLOCOCCUS AUREUS
Descriptor:Nicking enzyme, CALCIUM ION
Authors:Betts, L.
Deposit date:2012-11-01
Release date:2013-01-30
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular basis of antibiotic multiresistance transfer in Staphylococcus aureus.
Proc.Natl.Acad.Sci.USA, 110, 2013
5VVR
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TERNARY COMPLEX OF RNA POL II, TRANSCRIPTION SCAFFOLD AND RAD26
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Lahiri, I., Leschziner, A.E.
Deposit date:2017-05-19
Release date:2017-11-22
Last modified:2017-12-13
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Structural basis for the initiation of eukaryotic transcription-coupled DNA repair.
Nature, 551, 2017
5VVS
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RNA POL II ELONGATION COMPLEX
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Lahiri, I., Leschziner, A.E.
Deposit date:2017-05-20
Release date:2017-11-22
Last modified:2017-12-13
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:Structural basis for the initiation of eukaryotic transcription-coupled DNA repair.
Nature, 551, 2017
1HCR
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HIN RECOMBINASE BOUND TO DNA: THE ORIGIN OF SPECIFICITY IN MAJOR AND MINOR GROOVE INTERACTIONS
Descriptor:DNA (5'-D(*TP*GP*TP*TP*TP*TP*TP*GP*AP*TP*AP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*TP*AP*TP*CP*AP*AP*AP*AP*AP*C)-3'), PROTEIN (HIN RECOMBINASE)
Authors:Feng, J.-A., Johnson, R.C., Dickerson, R.E.
Deposit date:1993-12-17
Release date:1994-04-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Hin recombinase bound to DNA: the origin of specificity in major and minor groove interactions.
Science, 263, 1994