Author results

1EJ8
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CRYSTAL STRUCTURE OF DOMAIN 2 OF THE YEAST COPPER CHAPERONE FOR SUPEROXIDE DISMUTASE (LYS7) AT 1.55 A RESOLUTION
Descriptor:LYS7, CALCIUM ION
Authors:Hall, L.T., Sanchez, R.J., Holloway, S.P., Zhu, H., Stine, J.E., Lyons, T.J., Demeler, B., Schirf, V., Hansen, J.C., Nersissian, A.M., Valentine, J.S., Hart, P.J.
Deposit date:2000-03-01
Release date:2000-04-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:X-ray crystallographic and analytical ultracentrifugation analyses of truncated and full-length yeast copper chaperones for SOD (LYS7): a dimer-dimer model of LYS7-SOD association and copper delivery.
Biochemistry, 39, 2000
1IX2
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CRYSTAL STRUCTURE OF SELENOMETHIONINE PCOC, A COPPER RESISTANCE PROTEIN FROM ESCHERICHIA COLI
Descriptor:PcoC copper resistance protein
Authors:Wernimont, A.K., Huffman, D.L., Finney, L.A., Demeler, B., O'Halloran, T.V., Rosenzweig, A.C.
Deposit date:2002-06-10
Release date:2002-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structure and dimerization equilibria of PcoC, a methionine-rich copper resistance protein from Escherichia coli
J.BIOL.INORG.CHEM., 8, 2003
1LYQ
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CRYSTAL STRUCTURE OF PCOC, A METHIONINE RICH COPPER RESISTANCE PROTEIN FROM ESCHERICHIA COLI
Descriptor:PcoC copper resistance protein, GLYCEROL
Authors:Wernimont, A.K., Huffman, D.L., Finney, L.A., Demeler, B., O'Halloran, T.V., Rosenzweig, A.C.
Deposit date:2002-06-07
Release date:2002-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure and dimerization equilibria of PcoC, a methionine-rich copper resistance protein from Escherichia coli
J.BIOL.INORG.CHEM., 8, 2003
1TKV
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SOLUTION STRUCTURE OF T4 ASIA DIMER
Descriptor:10 kDa anti-sigma factor
Authors:Lambert, L.J., Schirf, V., Demeler, B., Cadene, M., Werner, M.H.
Deposit date:2004-06-09
Release date:2004-06-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Flipping a genetic switch by subunit exchange
Embo J., 20, 2001
1TL6
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SOLUTION STRUCTURE OF T4 BACTERIPHAGE ASIA MONOMER
Descriptor:10 kDa anti-sigma factor
Authors:Lambert, L.J., Wei, Y., Schirf, V., Demeler, B., Werner, M.H.
Deposit date:2004-06-09
Release date:2005-06-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:T4 AsiA blocks DNA recognition by remodeling sigma70 region 4
Embo J., 23, 2004
1TLH
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T4 ASIA BOUND TO SIGMA70 REGION 4
Descriptor:10 kDa anti-sigma factor, RNA polymerase sigma factor rpoD
Authors:Lambert, L.J., Wei, Y., Schirf, V., Demeler, B., Werner, M.H.
Deposit date:2004-06-09
Release date:2004-11-23
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:T4 AsiA blocks DNA recognition by remodeling sigma(70) region 4
Embo J., 23, 2004
1TTY
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SOLUTION STRUCTURE OF SIGMA A REGION 4 FROM THERMOTOGA MARITIMA
Descriptor:RNA polymerase sigma factor rpoD
Authors:Lambert, L.J., Wei, Y., Schirf, V., Demeler, B., Werner, M.H.
Deposit date:2004-06-23
Release date:2004-11-23
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:T4 AsiA blocks DNA recognition by remodeling sigma(70) region 4
Embo J., 23, 2004
1YVL
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STRUCTURE OF UNPHOSPHORYLATED STAT1
Descriptor:Signal transducer and activator of transcription 1-alpha/beta, 5-residue peptide, GOLD ION
Authors:Mao, X., Ren, Z., Parker, G.N., Sondermann, H., Pastorello, M.A., Wang, W., McMurray, J.S., Demeler, B., Darnell Jr., J.E., Chen, X.
Deposit date:2005-02-16
Release date:2005-03-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural bases of unphosphorylated STAT1 association and receptor binding.
Mol.Cell, 17, 2005
1Z09
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SOLUTION STRUCTURE OF KM23
Descriptor:Dynein light chain 2A, cytoplasmic
Authors:Ilangovan, U., Ding, W., Mulder, K., Hinck, A.P., Zuniga, J., Trbovich, J.A., Demeler, B., Groppe, J.C.
Deposit date:2005-03-01
Release date:2005-08-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure and Dynamics of the Homodimeric Dynein Light Chain km23.
J.Mol.Biol., 352 (2), 2005
2AEX
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THE 1.58A CRYSTAL STRUCTURE OF HUMAN COPROPORPHYRINOGEN OXIDASE REVEALS THE STRUCTURAL BASIS OF HEREDITARY COPROPORPHYRIA
Descriptor:Coproporphyrinogen III oxidase, mitochondrial, CITRIC ACID
Authors:Lee, D.S., Flachsova, E., Bodnarova, M., Demeler, B., Martasek, P., Raman, C.S.
Deposit date:2005-07-24
Release date:2005-08-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structural basis of hereditary coproporphyria.
Proc.Natl.Acad.Sci.USA, 102, 2005
2N1L
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SOLUTION STRUCTURE OF THE BCOR PUFD
Descriptor:BCL-6 corepressor
Authors:Wong, S.J., Gearhart, M.D., Ha, D.J., Corcoran, C.M., Diaz, V., Taylor, A.B., Schirf, V., Ilangovan, U., Hinck, A.P., Demeler, B., Hart, J., Bardwell, V.J., Kim, C.A.
Deposit date:2015-04-06
Release date:2016-04-06
Method:SOLUTION NMR
Cite:Structural basis for the hierarchical assembly of the core of PRC1.1
To be Published
2VER
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STRUCTURAL MODEL FOR THE COMPLEX BETWEEN THE DR ADHESINS AND CARCINOEMBRYONIC ANTIGEN (CEA)
Descriptor:AFIMBRIAL ADHESIN AFA-III, ARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 5, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate
Authors:Korotkova, N., Yang, Y., Le Trong, I., Cota, E., Demeler, B., Marchant, J., Thomas, W.E., Stenkamp, R.E., Moseley, S.L., Matthews, S.
Deposit date:2007-10-26
Release date:2008-01-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Binding of Dr Adhesins of Escherichia Coli to Carcinoembryonic Antigen Triggers Receptor Dissociation.
Mol.Microbiol., 67, 2008
3JCA
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CORE MODEL OF THE MOUSE MAMMARY TUMOR VIRUS INTASOME
Descriptor:Integrase, 5'-D(*AP*AP*TP*GP*CP*CP*GP*CP*AP*GP*TP*CP*GP*GP*CP*CP*GP*AP*CP*CP*TP*G)-3', 5'-D(*CP*AP*GP*GP*TP*CP*GP*GP*CP*CP*GP*AP*CP*TP*GP*CP*GP*GP*CP*A)-3', ...
Authors:Lyumkis, D.L., Ballandras-Colas, A., Brown, M., Cook, N.J., Dewdney, T.G., Demeler, B., Cherepanov, P., Engelman, A.N.
Deposit date:2015-11-24
Release date:2016-02-17
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function.
Nature, 530, 2016
3PMR
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CRYSTAL STRUCTURE OF E2 DOMAIN OF HUMAN AMYLOID PRECURSOR-LIKE PROTEIN 1
Descriptor:Amyloid-like protein 1, PHOSPHATE ION
Authors:Lee, S., Xue, Y., Hu, J., Wang, Y., Liu, X., Demeler, B., Ha, Y.
Deposit date:2010-11-17
Release date:2011-06-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:The E2 Domains of APP and APLP1 Share a Conserved Mode of Dimerization.
Biochemistry, 50, 2011
3QQD
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HUMAN SOD1 H80R VARIANT, P212121 CRYSTAL FORM
Descriptor:Superoxide dismutase [Cu-Zn], ZINC ION, SULFATE ION
Authors:Seetharaman, S.V., Winkler, D.D., Taylor, A.B., Cao, X., Whitson, L.J., Doucette, P.A., Valentine, J.S., Schirf, V., Demeler, B., Carroll, M.C., Culotta, V.C., Hart, P.J.
Deposit date:2011-02-15
Release date:2011-03-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.653 Å)
Cite:Disrupted zinc-binding sites in structures of pathogenic SOD1 variants D124V and H80R.
Biochemistry, 49, 2010
4RMK
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CRYSTAL STRUCTURE OF THE OLFACTOMEDIN DOMAIN OF LATROPHILIN 3 IN P65 CRYSTAL FORM
Descriptor:Latrophilin-3, CALCIUM ION
Authors:Ranaivoson, F.M., Liu, Q., Martini, F., Bergami, F., Von daake, S., Li, S., Demeler, B., Hendrickson, W.A., Comoletti, D.
Deposit date:2014-10-21
Release date:2015-08-19
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.606 Å)
Cite:Structural and Mechanistic Insights into the Latrophilin3-FLRT3 Complex that Mediates Glutamatergic Synapse Development.
Structure, 23, 2015
4RML
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CRYSTAL STRUCTURE OF THE OLFACTOMEDIN DOMAIN OF LATROPHILIN 3 IN C2221 CRYSTAL FORM
Descriptor:Latrophilin-3, MAGNESIUM ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Ranaivoson, F.M., Liu, Q., Martini, F., Bergami, F., Von daake, S., Li, S., Demeler, B., Hendrickson, W.A., Comoletti, D.
Deposit date:2014-10-21
Release date:2015-08-19
Last modified:2015-10-07
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Structural and Mechanistic Insights into the Latrophilin3-FLRT3 Complex that Mediates Glutamatergic Synapse Development.
Structure, 23, 2015
4YEB
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STRUCTURAL CHARACTERIZATION OF A SYNAPTIC ADHESION COMPLEX
Descriptor:Latrophilin-3, Fibronectin leucine rich transmembrane protein 3, CALCIUM ION, ...
Authors:Ranaivoson, F.M., Liu, Q., Martini, F., Bergami, F., von Daake, S., Li, S., Lee, D., Demeler, B., Hendrickson, W.A., Comoletti, D.
Deposit date:2015-02-23
Release date:2015-08-19
Last modified:2015-09-23
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Structural and Mechanistic Insights into the Latrophilin3-FLRT3 Complex that Mediates Glutamatergic Synapse Development.
Structure, 23, 2015
5YPP
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CRYSTAL STRUCTURE OF ILVN.VAL-1A
Descriptor:Acetolactate synthase isozyme 1 small subunit, VALINE, DI(HYDROXYETHYL)ETHER, ...
Authors:Sarma, S.P., Bansal, A., Schindelin, H., Demeler, B.
Deposit date:2017-11-02
Release date:2018-09-19
Last modified:2019-04-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases.
Biochemistry, 2019
5YPW
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CRYSTAL STRUCTURE OF ILVN.VAL-1B
Descriptor:Acetolactate synthase isozyme 1 small subunit, VALINE
Authors:Sarma, S.P., Bansal, A., Schindelin, H., Demeler, B.
Deposit date:2017-11-03
Release date:2018-09-19
Last modified:2019-04-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases.
Biochemistry, 2019
5YPY
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CRYSTAL STRUCTURE OF ILVN. VAL-1C
Descriptor:Acetolactate synthase isozyme 1 small subunit, VALINE
Authors:Sarma, S.P., Bansal, A., Schindelin, H., Demeler, B.
Deposit date:2017-11-04
Release date:2018-09-19
Last modified:2019-04-10
Method:X-RAY DIFFRACTION (1.966 Å)
Cite:Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases.
Biochemistry, 2019
5YUM
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CRYSTALLOGRAPHIC STRUCTURES OF ILVN.VAL/ILE COMPLEXES:CONFORMATIONAL SELECTIVITY FOR FEEDBACK INHIBITION OF AHASS
Descriptor:Acetolactate synthase isozyme 1 small subunit, ISOLEUCINE, COBALT (II) ION
Authors:Sarma, S.P., Bansal, A., Schindelin, H., Demeler, B.
Deposit date:2017-11-22
Release date:2018-09-19
Last modified:2019-04-10
Method:X-RAY DIFFRACTION (2.432 Å)
Cite:Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases.
Biochemistry, 2019
5TX2
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MINIATURE TGF-BETA2 3-MUTANT MONOMER
Descriptor:Transforming growth factor beta-2
Authors:Taylor, A.B., Kim, S.K., Hart, P.J., Hinck, A.P.
Deposit date:2016-11-15
Release date:2017-03-01
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:An engineered transforming growth factor beta (TGF-beta ) monomer that functions as a dominant negative to block TGF-beta signaling.
J. Biol. Chem., 292, 2017
5TX4
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DERIVATIVE OF MOUSE TGF-BETA2, WITH A DELETION OF RESIDUES 52-71 AND K25R, R26K, L51R, A74K, C77S, L89V, I92V, K94R T95K, I98V SINGLE AMINO ACID SUBSTITUTIONS, BOUND TO HUMAN TGF-BETA TYPE II RECEPTOR ECTODOMAIN RESIDUES 15-130
Descriptor:TGF-beta receptor type-2, Transforming growth factor beta-2
Authors:Hinck, A.P., Kim, S.
Deposit date:2016-11-15
Release date:2017-03-01
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.876 Å)
Cite:An engineered transforming growth factor beta (TGF-beta ) monomer that functions as a dominant negative to block TGF-beta signaling.
J. Biol. Chem., 292, 2017
5TX6
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STRUCTURE OF TGF-BETA2 DERIVATIVE WITH DELETION OF RESIDUES 52-71 AND 10 SINGLE AMINO ACID MUTATIONS (MMTGF-BETA2-7M)
Descriptor:Transforming growth factor beta-2, CALCIUM ION
Authors:Petrunak, E.M., Hinck, A.P.
Deposit date:2016-11-15
Release date:2017-03-01
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.746 Å)
Cite:An engineered transforming growth factor beta (TGF-beta ) monomer that functions as a dominant negative to block TGF-beta signaling.
J. Biol. Chem., 292, 2017
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