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2GQC
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BU of 2gqc by Molmil
Solution structure of the N-terminal domain of Rhomboid Intramembrane Protease from P. aeruginosa
Descriptor: Rhomboid Intramembrane Protease
Authors:Dutta, K, Del Rio, A, Chavez, J, Ubarretxena-Belandia, I, Ghose, R.
Deposit date:2006-04-20
Release date:2007-03-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure and dynamics of the N-terminal cytosolic domain of rhomboid intramembrane protease from Pseudomonas aeruginosa: insights into a functional role in intramembrane proteolysis.
J.Mol.Biol., 365, 2007
1AU7
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BU of 1au7 by Molmil
PIT-1 MUTANT/DNA COMPLEX
Descriptor: CONSENSUS DNA 25-MER, DNA (5'-D(*CP*TP*TP*CP*CP*TP*CP*AP*TP*GP*TP*AP*TP*AP*TP*AP*C P*AP*TP*GP*AP*GP* GP*A)-3'), PROTEIN PIT-1
Authors:Jacobson, E.M, Li, P, Leon-Del-Rio, A, Rosenfeld, M.G, Aggarwal, A.K.
Deposit date:1997-09-12
Release date:1998-01-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of Pit-1 POU domain bound to DNA as a dimer: unexpected arrangement and flexibility.
Genes Dev., 11, 1997
6ZRB
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BU of 6zrb by Molmil
Crystal structure of SMYD3 conjugate with piperidine-based covalent inhibitor EM127
Descriptor: ACETATE ION, Histone-lysine N-methyltransferase SMYD3, N-[1-(2-Chloroacetyl)piperidin-4-yl]-5-cyclopropyl-1,2-oxazole-3-carboxamide, ...
Authors:Talibov, V.O, Eriksson, D.
Deposit date:2020-07-13
Release date:2022-07-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Discovery of the 4-aminopiperidine-based compound EM127 for the site-specific covalent inhibition of SMYD3
Eur.J.Med.Chem., 2022
6YUH
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BU of 6yuh by Molmil
Crystal structure of SMYD3 with diperodon R enantiomer bound to allosteric site
Descriptor: Diperodon, GLYCEROL, Histone-lysine N-methyltransferase SMYD3, ...
Authors:Cederfelt, D, Talibov, V.O, Dobritzsch, D, Danielson, U.H.
Deposit date:2020-04-27
Release date:2021-01-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Discovery of an Allosteric Ligand Binding Site in SMYD3 Lysine Methyltransferase.
Chembiochem, 22, 2021

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