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4ON9
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BU of 4on9 by Molmil
DECH box helicase domain
Descriptor: CHLORIDE ION, Probable ATP-dependent RNA helicase DDX58, SULFATE ION
Authors:Deimling, T, Witte, G, Hopfner, K.P.
Deposit date:2014-01-28
Release date:2014-07-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Crystal and solution structure of the human RIG-I SF2 domain
Acta Crystallogr.,Sect.F, 70, 2014
4JC5
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BU of 4jc5 by Molmil
Immune activator bound to receptor
Descriptor: (9-oxoacridin-10(9H)-yl)acetic acid, Transmembrane protein 173
Authors:Deimling, T, Hopfner, K.P.
Deposit date:2013-02-21
Release date:2013-05-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Species-specific detection of the antiviral small-molecule compound CMA by STING.
Embo J., 32, 2013
4KB6
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BU of 4kb6 by Molmil
Structure of porcine cyclic GMP AMP synthase (CGAS) in complex with DNA, ATP and GTP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*CP*GP*AP*CP*GP*CP*TP*AP*GP*CP*GP*TP*CP*G)-3'), GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Deimling, T, Hopfner, K.-P.
Deposit date:2013-04-23
Release date:2013-06-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.0754 Å)
Cite:Structural mechanism of cytosolic DNA sensing by cGAS.
Nature, 498, 2013
4YVZ
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BU of 4yvz by Molmil
Structure of Thermotoga maritima DisA in complex with 3'-dATP/Mn2+
Descriptor: 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, DNA integrity scanning protein DisA, MANGANESE (II) ION
Authors:Mueller, M, Deimling, T, Hopfner, K.-P, Witte, G.
Deposit date:2015-03-20
Release date:2015-06-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.495 Å)
Cite:Structural analysis of the diadenylate cyclase reaction of DNA-integrity scanning protein A (DisA) and its inhibition by 3'-dATP.
Biochem.J., 469, 2015
4YXM
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BU of 4yxm by Molmil
Structure of Thermotoga maritima DisA D75N mutant with reaction product c-di-AMP
Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, (4S)-2-METHYL-2,4-PENTANEDIOL, DNA integrity scanning protein DisA
Authors:Mueller, M, Deimling, T, Hopfner, K.-P, Witte, G.
Deposit date:2015-03-23
Release date:2015-06-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural analysis of the diadenylate cyclase reaction of DNA-integrity scanning protein A (DisA) and its inhibition by 3'-dATP.
Biochem.J., 469, 2015
4YXJ
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BU of 4yxj by Molmil
Structure of Thermotoga maritima DisA in complex with ApCpp
Descriptor: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA integrity scanning protein DisA
Authors:Mueller, M, Deimling, T, Hopfner, K.-P, Witte, G.
Deposit date:2015-03-23
Release date:2015-06-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural analysis of the diadenylate cyclase reaction of DNA-integrity scanning protein A (DisA) and its inhibition by 3'-dATP.
Biochem.J., 469, 2015
3TBK
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BU of 3tbk by Molmil
Mouse RIG-I ATPase Domain
Descriptor: 1,2-ETHANEDIOL, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RIG-I Helicase Domain
Authors:Civril, F, Bennett, M.D, Hopfner, K.-P.
Deposit date:2011-08-07
Release date:2011-10-26
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:The RIG-I ATPase domain structure reveals insights into ATP-dependent antiviral signalling.
Embo Rep., 12, 2011
4JLX
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BU of 4jlx by Molmil
Structure of porcine cyclic GMP-AMP synthase (cGAS)
Descriptor: GLYCEROL, MALONATE ION, TETRAETHYLENE GLYCOL, ...
Authors:Civril, F, Hopfner, K.P.
Deposit date:2013-03-13
Release date:2013-06-12
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.004 Å)
Cite:Structural mechanism of cytosolic DNA sensing by cGAS
Nature, 498, 2013
4JLZ
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BU of 4jlz by Molmil
Structure of porcine cGAS in complex with bound UTP
Descriptor: MAGNESIUM ION, URIDINE 5'-TRIPHOSPHATE, Uncharacterized protein, ...
Authors:Civril, F, Hopfner, K.P.
Deposit date:2013-03-13
Release date:2013-06-12
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Structural mechanism of cytosolic DNA sensing by cGAS
Nature, 498, 2013

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