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1O9V
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F17-AG LECTIN DOMAIN FROM ESCHERICHIA COLI IN COMPLEX WITH A SELENIUM CARBOHYDRATE DERIVATIVE
Descriptor:F17-AG LECTIN DOMAIN, METHYL 2-ACETAMIDO-1,2-DIDEOXY-1-SELENO-BETA-D-GLUCOPYRANOSIDE
Authors:Buts, L., De Genst, E., Loris, R., Oscarson, S., Lahmann, M., Messens, J., Brosens, E., Wyns, L., Bouckaert, J., De Greve, H.
Deposit date:2002-12-20
Release date:2003-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The Fimbrial Adhesin F17-G of Enterotoxigenic Escherichia Coli Has an Immunoglobulin-Like Lectin Domain that Binds N-Acetylglucosamine
Mol.Microbiol., 49, 2003
1O9W
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F17-AG LECTIN DOMAIN FROM ESCHERICHIA COLI IN COMPLEX WITH N-ACETYL-GLUCOSAMINE
Descriptor:F17A-G FIMBRIAL ADHESIN, N-ACETYL-D-GLUCOSAMINE
Authors:Buts, L., De Genst, E., Loris, R., Oscarson, S., Lahmann, M., Messens, J., Brosens, E., Wyns, L., Bouckaert, J., De Greve, H.
Deposit date:2002-12-20
Release date:2003-05-29
Last modified:2012-01-18
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The Fimbrial Adhesin F17-G of Enterotoxigenic Escherichia Coli Has an Immunoglobulin-Like Lectin Domain that Binds N-Acetylglucosamine
Mol.Microbiol., 49, 2003
1O9Z
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F17-AG LECTIN DOMAIN FROM ESCHERICHIA COLI (LIGAND FREE)
Descriptor:F17-AG LECTIN DOMAIN
Authors:Buts, L., De Genst, E., Loris, R., Oscarson, S., Lahmann, M., Messens, J., Brosens, E., Wyns, L., Bouckaert, J., De Greve, H.
Deposit date:2002-12-23
Release date:2003-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The Fimbrial Adhesin F17-G of Enterotoxigenic Escherichia Coli Has an Immunoglobulin-Like Lectin Domain that Binds N-Acetylglucosamine
Mol.Microbiol., 49, 2003
4B4P
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CRYSTAL STRUCTURE OF THE LECTIN DOMAIN OF F18 FIMBRIAL ADHESIN FEDF.
Descriptor:F18 FIMBRIAL ADHESIN AC, BROMIDE ION, SULFATE ION
Authors:Moonens, K., Bouckaert, J., Coddens, A., Tran, T., Panjikar, S., De Kerpel, M., Cox, E., Remaut, H., De Greve, H.
Deposit date:2012-07-31
Release date:2012-08-15
Last modified:2012-10-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Insight in Histo-Blood Group Binding by the F18 Fimbrial Adhesin Fedf.
Mol.Microbiol., 86, 2012
4B4Q
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CRYSTAL STRUCTURE OF THE LECTIN DOMAIN OF F18 FIMBRIAL ADHESIN FEDF IN COMPLEX WITH BLOOD GROUP A TYPE 1 HEXASACCHARIDE
Descriptor:F18 FIMBRIAL ADHESIN AC, N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE, BETA-D-GALACTOSE, ...
Authors:Moonens, K., Bouckaert, J., Coddens, A., Tran, T., Panjikar, S., De Kerpel, M., Cox, E., Remaut, H., De Greve, H.
Deposit date:2012-07-31
Release date:2012-08-15
Last modified:2012-10-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insight in Histo-Blood Group Binding by the F18 Fimbrial Adhesin Fedf.
Mol.Microbiol., 86, 2012
4B4R
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CRYSTAL STRUCTURE OF THE LECTIN DOMAIN OF F18 FIMBRIAL ADHESIN FEDF IN COMPLEX WITH BLOOD GROUP B TYPE 1 HEXASACCHARIDE
Descriptor:F18 FIMBRIAL ADHESIN AC, ALPHA D-GALACTOSE, BETA-D-GALACTOSE, ...
Authors:Moonens, K., Bouckaert, J., Coddens, A., Tran, T., Panjikar, S., De Kerpel, M., Cox, E., Remaut, H., De Greve, H.
Deposit date:2012-07-31
Release date:2012-08-15
Last modified:2012-10-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Insight in Histo-Blood Group Binding by the F18 Fimbrial Adhesin Fedf.
Mol.Microbiol., 86, 2012
4WEM
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CO-COMPLEX STRUCTURE OF THE F4 FIMBRIAL ADHESIN FAEG VARIANT AC WITH LLAMA SINGLE DOMAIN ANTIBODY V1
Descriptor:K88 fimbrial protein AC, Anti-F4+ETEC bacteria VHH variable region, PHOSPHATE ION
Authors:Moonens, K., Van den Broeck, I., Pardon, E., De Kerpel, M., Remaut, H., De Greve, H.
Deposit date:2014-09-10
Release date:2015-02-04
Last modified:2015-04-15
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural insight in the inhibition of adherence of F4 fimbriae producing enterotoxigenic Escherichia coli by llama single domain antibodies.
Vet. Res., 46, 2015
4WEN
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CO-COMPLEX STRUCTURE OF THE F4 FIMBRIAL ADHESIN FAEG VARIANT AC WITH LLAMA SINGLE DOMAIN ANTIBODY V2
Descriptor:K88 fimbrial protein AC, Anti-F4+ETEC bacteria VHH variable region
Authors:Moonens, K., Van den Broeck, I., Pardon, E., De Kerpel, M., Remaut, H., De Greve, H.
Deposit date:2014-09-10
Release date:2015-02-04
Last modified:2015-04-15
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural insight in the inhibition of adherence of F4 fimbriae producing enterotoxigenic Escherichia coli by llama single domain antibodies.
Vet. Res., 46, 2015
4WEU
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CO-COMPLEX STRUCTURE OF THE F4 FIMBRIAL ADHESIN FAEG VARIANT AD WITH LLAMA SINGLE DOMAIN ANTIBODY V3
Descriptor:Anti-F4+ETEC bacteria VHH variable region, K88 fimbrial protein AD
Authors:Moonens, K., Van den Broeck, I., Pardon, E., De Kerpel, M., Remaut, H., De Greve, H.
Deposit date:2014-09-11
Release date:2015-02-04
Last modified:2015-04-15
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structural insight in the inhibition of adherence of F4 fimbriae producing enterotoxigenic Escherichia coli by llama single domain antibodies.
Vet. Res., 46, 2015
4WE2
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DONOR STRAND COMPLEMENTED FAEG OF F4AB FIMBRIAE
Descriptor:K88 fimbrial protein AB
Authors:Moonens, K., Van den Broeck, I., De Kerpel, M., Deboeck, F., Raymaekers, H., Remaut, H., De Greve, H.
Deposit date:2014-09-09
Release date:2015-02-04
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural and Functional Insight into the Carbohydrate Receptor Binding of F4 Fimbriae-producing Enterotoxigenic Escherichia coli.
J.Biol.Chem., 290, 2015
4WEI
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CRYSTAL STRUCTURE OF THE F4 FIMBRIAL ADHESIN FAEG IN COMPLEX WITH LACTOSE
Descriptor:K88 fimbrial protein AD, ALPHA-D-GLUCOSE, BETA-D-GALACTOSE
Authors:Moonens, K., Van den Broeck, I., De Kerpel, M., Deboeck, F., Raymaekers, H., Remaut, H., De Greve, H.
Deposit date:2014-09-10
Release date:2015-02-04
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Functional Insight into the Carbohydrate Receptor Binding of F4 Fimbriae-producing Enterotoxigenic Escherichia coli.
J.Biol.Chem., 290, 2015
4P2C
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COMPLEX OF SHIGA TOXIN 2E WITH A NEUTRALIZING SINGLE-DOMAIN ANTIBODY
Descriptor:Shiga toxin 2e, subunit A, subunit B, ...
Authors:Lo, A.W.H., Moonens, K., De Kerpel, M., Brys, L., Pardon, E., Remaut, H., De Greve, H.
Deposit date:2014-03-03
Release date:2014-07-30
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.818 Å)
Cite:The Molecular Mechanism of Shiga Toxin Stx2e Neutralization by a Single-domain Antibody Targeting the Cell Receptor-binding Domain.
J.Biol.Chem., 289, 2014
4W6W
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CO-COMPLEX STRUCTURE OF THE LECTIN DOMAIN OF F18 FIMBRIAL ADHESIN FEDF WITH INHIBITORY NANOBODY NBFEDF6
Descriptor:F18 fimbrial adhesin AC, NbFedF6
Authors:Moonens, K., De Kerpel, M., Annelies, C., Cox, E., Pardon, E., Remaut, H., De Greve, H.
Deposit date:2014-08-21
Release date:2014-12-17
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Nanobody Mediated Inhibition of Attachment of F18 Fimbriae Expressing Escherichia coli.
Plos One, 9, 2014
4W6X
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CO-COMPLEX STRUCTURE OF THE LECTIN DOMAIN OF F18 FIMBRIAL ADHESIN FEDF WITH INHIBITORY NANOBODY NBFEDF7
Descriptor:F18 fimbrial adhesin AC, Nanobody NbFedF7
Authors:Moonens, K., De Kerpel, M., Coddens, A., Cox, E., Pardon, E., Remaut, H., De Greve, H.
Deposit date:2014-08-21
Release date:2014-12-17
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Nanobody Mediated Inhibition of Attachment of F18 Fimbriae Expressing Escherichia coli.
Plos One, 9, 2014
4W6Y
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CO-COMPLEX STRUCTURE OF THE LECTIN DOMAIN OF F18 FIMBRIAL ADHESIN FEDF WITH INHIBITORY NANOBODY NBFEDF9
Descriptor:F18 fimbrial adhesin AC, Nanobody NbFedF9, SULFATE ION
Authors:Moonens, K., De Kerpel, M., Coddens, A., Cox, E., Pardon, E., Remaut, H., De Greve, H.
Deposit date:2014-08-21
Release date:2014-12-17
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Nanobody Mediated Inhibition of Attachment of F18 Fimbriae Expressing Escherichia coli.
Plos One, 9, 2014
1TR7
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FIMH ADHESIN RECEPTOR BINDING DOMAIN FROM UROPATHOGENIC E. COLI
Descriptor:FimH protein, BUTYL ALPHA-D-MANNOPYRANOSIDE, CACODYLATE ION, ...
Authors:Bouckaert, J., Berglund, J., Schembri, M., De Genst, E., Cools, L., Wuhrer, M., Hung, C.S., Pinkner, J., Slattegard, R., Zavialov, A., Choudhury, D., Langermann, S., Hultgren, S.J., Wyns, L., Klemm, P., Oscarson, S., Knight, S.D., De Greve, H.
Deposit date:2004-06-21
Release date:2005-05-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Receptor binding studies disclose a novel class of high-affinity inhibitors of the Escherichia coli FimH adhesin
Mol.Microbiol., 55, 2005
4ELY
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CCDBVFI:GYRA14EC
Descriptor:DNA gyrase subunit A, CcdB, SULFATE ION, ...
Authors:De Jonge, N., Simic, R., Buts, L., Haesaerts, S., Roelants, K., Garcia-Pino, A., Sterckx, Y., De Greve, H., Lah, J., Loris, R.
Deposit date:2012-04-11
Release date:2012-05-30
Last modified:2013-01-02
Method:X-RAY DIFFRACTION (1.932 Å)
Cite:Alternative interactions define gyrase specificity in the CcdB family.
Mol.Microbiol., 84, 2012
4ELZ
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CCDBVFI:GYRA14VFI
Descriptor:DNA gyrase subunit A, CcdB, GLYCEROL
Authors:De Jonge, N., Simic, M., Buts, L., Haesaerts, S., Roelants, K., Garcia-Pino, A., Sterckx, Y., De Greve, H., Lah, J., Loris, R.
Deposit date:2012-04-11
Release date:2012-05-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Alternative interactions define gyrase specificity in the CcdB family.
Mol.Microbiol., 84, 2012
5MI3
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STRUCTURE OF PHOSPHORYLATED TRANSLATION ELONGATION FACTOR EF-TU FROM E. COLI
Descriptor:Elongation factor Tu 1, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Talavera, A., Hendrix, J., Versees, W., De Gieter, S., Castro-Roa, D., Jurenas, D., Van Nerom, K., Vandenberk, N., Barth, A., De Greve, H., Hofkens, J., Zenkin, N., Loris, R., Garcia-Pino, A.
Deposit date:2016-11-27
Release date:2017-12-20
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors.
Sci Adv, 4, 2018
5MI8
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STRUCTURE OF THE PHOSPHOMIMETIC MUTANT OF EF-TU T383E
Descriptor:Elongation factor Tu 1, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Talavera, A., Hendrix, J., Versees, W., De Gieter, S., Castro-Roa, D., Jurenas, D., Van Nerom, K., Vandenberk, N., Barth, A., De Greve, H., Hofkens, J., Zenkin, N., Loris, R., Garcia-Pino, A.
Deposit date:2016-11-27
Release date:2017-12-20
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Structure of the phosphomimetic mutant of EF-Tu T383E
To Be Published
5MI9
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STRUCTURE OF THE PHOSPHOMIMETIC MUTANT OF THE ELONGATION FACTOR EF-TU T62E
Descriptor:Elongation factor Tu 1, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Talavera, A., Hendrix, J., Versees, W., De Gieter, S., Castro-Roa, D., Jurenas, D., Van Nerom, K., Vandenberk, N., Barth, A., De Greve, H., Hofkens, J., Zenkin, N., Loris, R., Garcia-Pino, A.
Deposit date:2016-11-27
Release date:2017-12-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of the phosphomimetic mutant of the elongation factor EF-Tu T62E
To Be Published
1UWF
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1.7 A RESOLUTION STRUCTURE OF THE RECEPTOR BINDING DOMAIN OF THE FIMH ADHESIN FROM UROPATHOGENIC E. COLI
Descriptor:FIMH PROTEIN, BUTYL ALPHA-D-MANNOPYRANOSIDE, GLYCEROL
Authors:Bouckaert, J., Berglund, J., Genst, E.D., Cools, L., Hung, C.-S., Wuhrer, M., Zavialov, A., Langermann, S., Hultgren, S., Wyns, L., Oscarson, S., Knight, S.D., De Greve, H.
Deposit date:2004-02-05
Release date:2005-02-16
Last modified:2015-04-15
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Receptor Binding Studies Disclose a Novel Class of High-Affinity Inhibitors of the Escherichia Coli Fimh Adhesin.
Mol.Microbiol., 55, 2005
1ZK5
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ESCHERICHIA COLI F17FG LECTIN DOMAIN COMPLEX WITH N-ACETYLGLUCOSAMINE
Descriptor:F17G adhesin subunit, N-ACETYL-D-GLUCOSAMINE
Authors:Buts, L., Wellens, A., Van Molle, I., De Genst, E., Wyns, L., Loris, R., Lahmann, M., Oscarson, S., De Greve, H., Bouckaert, J.
Deposit date:2005-05-02
Release date:2006-05-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Impact of natural variation in bacterial F17G adhesins on crystallization behaviour.
Acta Crystallogr.,Sect.D, 61, 2005
3GEA
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DONOR STRAND COMPLEMENTED FAEG MONOMER OF F4 VARIANT AD
Descriptor:K88 fimbrial protein AD, SULFATE ION, GLYCEROL
Authors:Van Molle, I., Moonens, K., Garcia-Pino, A., Buts, L., Bouckaert, J., De Greve, H.
Deposit date:2009-02-25
Release date:2009-10-20
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (1.699 Å)
Cite:Structural and thermodynamic characterization of pre- and postpolymerization states in the F4 fimbrial subunit FaeG
J.Mol.Biol., 394, 2009
3GEW
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FAEE-FAEG CHAPERONE-MAJOR PILIN COMPLEX OF F4 AD FIMBRIAE
Descriptor:Chaperone protein faeE, K88 fimbrial protein AD, SULFATE ION, ...
Authors:Van Molle, I., Moonens, K., Garcia-Pino, A., Buts, L., Bouckaert, J., De Greve, H.
Deposit date:2009-02-26
Release date:2009-10-20
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and thermodynamic characterization of pre- and postpolymerization states in the F4 fimbrial subunit FaeG
J.Mol.Biol., 394, 2009