5DSE
 
 | | Crystal Structure of the TTC7B/Hyccin Complex | | Descriptor: | Hyccin, Tetratricopeptide repeat protein 7B | | Authors: | Wu, X, Baskin, J.M, Reinisch, K.M, De Camilli, P. | | Deposit date: | 2015-09-17 | | Release date: | 2015-12-02 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | The leukodystrophy protein FAM126A (hyccin) regulates PtdIns(4)P synthesis at the plasma membrane.
Nat.Cell Biol., 18, 2016
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2AGA
 | | De-ubiquitinating function of ataxin-3: insights from the solution structure of the Josephin domain | | Descriptor: | Machado-Joseph disease protein 1 | | Authors: | Mao, Y, Senic-Matuglia, F, Di Fiore, P, Polo, S, Hodsdon, M.E, De Camilli, P. | | Deposit date: | 2005-07-26 | | Release date: | 2005-08-30 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Deubiquitinating function of ataxin-3: insights from the solution structure of the Josephin domain.
Proc.Natl.Acad.Sci.Usa, 102, 2005
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3QIS
 | | Recognition of the F&H motif by the Lowe Syndrome protein OCRL | | Descriptor: | Inositol polyphosphate 5-phosphatase OCRL-1, Protein FAM109A | | Authors: | Pirruccello, M, Swan, L.E, Folta-Stogniew, E, De Camilli, P. | | Deposit date: | 2011-01-27 | | Release date: | 2011-06-15 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Recognition of the F&H motif by the Lowe syndrome protein OCRL.
Nat.Struct.Mol.Biol., 18, 2011
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2QV2
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2KIG
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2KIE
 | | A PH domain within OCRL bridges clathrin mediated membrane trafficking to phosphoinositide metabolis | | Descriptor: | Inositol polyphosphate 5-phosphatase OCRL-1 | | Authors: | Mao, Y, Balkin, D.M, Zoncu, R, Erdmann, K, Tomasini, L, Hu, F, Jin, M.M, Hodsdon, M.E, De Camilli, P. | | Deposit date: | 2009-05-03 | | Release date: | 2009-07-21 | | Last modified: | 2022-03-16 | | Method: | SOLUTION NMR | | Cite: | A PH domain within OCRL bridges clathrin-mediated membrane trafficking to phosphoinositide metabolism
Embo J., 28, 2009
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4N5C
 | | Crystal structure of Ypp1 | | Descriptor: | Cargo-transport protein YPP1 | | Authors: | Wu, X, Chi, R.J, Baskin, J.M, Lucast, L, Burd, C.G, De Camilli, P, Reinisch, K.M. | | Deposit date: | 2013-10-09 | | Release date: | 2014-01-22 | | Last modified: | 2014-03-19 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | Structural insights into assembly and regulation of the plasma membrane phosphatidylinositol 4-kinase complex.
Dev.Cell, 28, 2014
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4N5A
 | | Crystal structure of Efr3 | | Descriptor: | Protein EFR3 | | Authors: | Wu, X, Chi, R.J, Baskin, J.M, Lucast, L, Burd, C.G, De Camilli, P, Reinisch, K.M. | | Deposit date: | 2013-10-09 | | Release date: | 2014-01-22 | | Last modified: | 2014-03-19 | | Method: | X-RAY DIFFRACTION (3.204 Å) | | Cite: | Structural insights into assembly and regulation of the plasma membrane phosphatidylinositol 4-kinase complex.
Dev.Cell, 28, 2014
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6BQ1
 | | Human PI4KIIIa lipid kinase complex | | Descriptor: | 5-{2-amino-1-[4-(morpholin-4-yl)phenyl]-1H-benzimidazol-6-yl}-N-(2-fluorophenyl)-2-methoxypyridine-3-sulfonamide, Phosphatidylinositol 4-kinase III alpha (PI4KA), Protein FAM126A, ... | | Authors: | Lees, J.A, Zhang, Y, Oh, M, Schauder, C.M, Yu, X, Baskin, J, Dobbs, K, Notarangelo, L.D, Camilli, P.D, Walz, T, Reinisch, K.M. | | Deposit date: | 2017-11-27 | | Release date: | 2017-12-13 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Architecture of the human PI4KIII alpha lipid kinase complex.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1EDU
 | | CRYSTAL STRUCTURE OF THE ENTH DOMAIN OF RAT EPSIN 1 | | Descriptor: | 1,2-ETHANEDIOL, EH domain binding protein EPSIN | | Authors: | Hyman, J.H, Chen, H, Decamilli, P, Brunger, A.T. | | Deposit date: | 2000-01-28 | | Release date: | 2000-05-10 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Epsin 1 undergoes nucleocytosolic shuttling and its eps15 interactor NH(2)-terminal homology (ENTH) domain, structurally similar to Armadillo and HEAT repeats, interacts with the transcription factor promyelocytic leukemia Zn(2)+ finger protein (PLZF).
J.Cell Biol., 149, 2000
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5TOD
 | | Transmembrane protein 24 SMP domain | | Descriptor: | Transmembrane protein 24 | | Authors: | Lees, J.A, Reinisch, K.M. | | Deposit date: | 2016-10-17 | | Release date: | 2017-03-01 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (2.96 Å) | | Cite: | Lipid transport by TMEM24 at ER-plasma membrane contacts regulates pulsatile insulin secretion.
Science, 355, 2017
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6CBC
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1AUV
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1AUX
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4P42
 | | Extended-Synaptotagmin 2, SMP - C2A - C2B Domains | | Descriptor: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-(2-{2-[2-(2-{2-[2-(2-{2-[4-(1,1,3,3-TETRAMETHYL-BUTYL)-PHENOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOX Y}-ETHOXY)-ETHANOL, Extended synaptotagmin-2 | | Authors: | Schauder, C.M, Wu, X, Reinisch, K.M. | | Deposit date: | 2014-03-10 | | Release date: | 2014-05-14 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.44 Å) | | Cite: | Structure of a lipid-bound extended synaptotagmin indicates a role in lipid transfer.
Nature, 510, 2014
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5LP0
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