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1LCT
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BU of 1lct by Molmil
STRUCTURE OF THE RECOMBINANT N-TERMINAL LOBE OF HUMAN LACTOFERRIN AT 2.0 ANGSTROMS RESOLUTION
Descriptor: CARBONATE ION, FE (III) ION, LACTOFERRIN
Authors:Day, C.L, Anderson, B.F, Baker, E.N.
Deposit date:1993-06-19
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the recombinant N-terminal lobe of human lactoferrin at 2.0 A resolution.
J.Mol.Biol., 232, 1993
1CWW
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BU of 1cww by Molmil
SOLUTION STRUCTURE OF THE CASPASE RECRUITMENT DOMAIN (CARD) FROM APAF-1
Descriptor: APOPTOTIC PROTEASE ACTIVATING FACTOR 1
Authors:Day, C.L, Dupont, C, Lackmann, M, Vaux, D.L, Hinds, M.G.
Deposit date:1999-08-26
Release date:2000-01-21
Last modified:2022-12-21
Method:SOLUTION NMR
Cite:Solution structure and mutagenesis of the caspase recruitment domain (CARD) from Apaf-1.
Cell Death Differ., 6, 1999
1DEB
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BU of 1deb by Molmil
CRYSTAL STRUCTURE OF THE N-TERMINAL COILED COIL DOMAIN FROM APC
Descriptor: ADENOMATOUS POLYPOSIS COLI PROTEIN, SULFATE ION
Authors:Day, C.L, Alber, T.
Deposit date:1999-11-14
Release date:2000-09-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the amino-terminal coiled-coil domain of the APC tumor suppressor.
J.Mol.Biol., 301, 2000
1WSX
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BU of 1wsx by Molmil
Solution structure of MCL-1
Descriptor: myeloid cell leukemia sequence 1
Authors:Day, C.L, Chen, L, Richardson, S.J, Harrison, P.J, Huang, D.C, Hinds, M.G.
Deposit date:2004-11-12
Release date:2004-11-23
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution Structure of Prosurvival Mcl-1 and Characterization of Its Binding by Proapoptotic BH3-only Ligands
J.Biol.Chem., 280, 2005
1RE6
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BU of 1re6 by Molmil
Localisation of Dynein Light Chains 1 and 2 and their Pro-apoptotic Ligands
Descriptor: dynein light chain 2
Authors:Day, C.L, Puthalakath, H, Skea, G, Strasser, A, Barsukov, I, Lian, L.Y, Huang, D.C, Hinds, M.G.
Deposit date:2003-11-06
Release date:2004-03-23
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Localization of dynein light chains 1 and 2 and their pro-apoptotic ligands.
Biochem.J., 377, 2004
2ROD
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BU of 2rod by Molmil
Solution Structure of MCL-1 Complexed with NoxaA
Descriptor: Induced myeloid leukemia cell differentiation protein Mcl-1 homolog, Noxa
Authors:Day, C.L, Smits, C, Fan, F.C, Lee, E.F, Fairlie, W.D, Hinds, M.G.
Deposit date:2008-03-17
Release date:2008-07-08
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Structure of the BH3 Domains from the p53-Inducible BH3-Only Proteins Noxa and Puma in Complex with Mcl-1
J.Mol.Biol., 380, 2008
2ROC
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BU of 2roc by Molmil
Solution structure of Mcl-1 Complexed with Puma
Descriptor: Bcl-2-binding component 3, Induced myeloid leukemia cell differentiation protein Mcl-1 homolog
Authors:Day, C.L, Smits, C, Fan, F.C, Lee, E.F, Fairlie, W.D, Hinds, M.G.
Deposit date:2008-03-17
Release date:2008-07-08
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Structure of the BH3 Domains from the p53-Inducible BH3-Only Proteins Noxa and Puma in Complex with Mcl-1
J.Mol.Biol., 380, 2008
2L9M
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BU of 2l9m by Molmil
Structure of cIAP1 CARD
Descriptor: Baculoviral IAP repeat-containing protein 2
Authors:Day, C.L, Rautureau, G.J.P, Hinds, M.G.
Deposit date:2011-02-21
Release date:2011-08-17
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:CARD-mediated autoinhibition of cIAP1's E3 ligase activity suppresses cell proliferation and migration.
Mol.Cell, 42, 2011
8GBQ
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BU of 8gbq by Molmil
Structure of RNF125 in complex with UbcH5b
Descriptor: E3 ubiquitin-protein ligase RNF125, GLYCEROL, Ubiquitin-conjugating enzyme E2 D2, ...
Authors:Middleton, A.J, Day, C.L, Fokkens, T.J.
Deposit date:2023-02-27
Release date:2023-07-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Zinc finger 1 of the RING E3 ligase, RNF125, interacts with the E2 to enhance ubiquitylation.
Structure, 31, 2023
8GCB
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BU of 8gcb by Molmil
Structure of RNF125 in complex with a UbcH5b~Ub conjugate
Descriptor: E3 ubiquitin-protein ligase RNF125, Ubiquitin-conjugating enzyme E2 D2, ZINC ION
Authors:Middleton, A.J, Day, C.L, Fokkens, T.J.
Deposit date:2023-03-01
Release date:2023-07-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Zinc finger 1 of the RING E3 ligase, RNF125, interacts with the E2 to enhance ubiquitylation.
Structure, 31, 2023
1VFE
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BU of 1vfe by Molmil
HUMAN LACTOFERRIN, N-TERMINAL LOBE MUTANT WITH ARG 121 REPLACED BY SER (R121S)
Descriptor: CARBONATE ION, FE (III) ION, HUMAN LACTOFERRIN
Authors:Faber, H.R, Day, C.L, Baker, E.N.
Deposit date:1996-10-01
Release date:1997-04-01
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mutation of arginine 121 in lactoferrin destabilizes iron binding by disruption of anion binding: crystal structures of R121S and R121E mutants.
Biochemistry, 35, 1996
1VFD
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BU of 1vfd by Molmil
HUMAN LACTOFERRIN, N-TERMINAL LOBE MUTANT WITH ARG 121 REPLACED BY GLU (R121E)
Descriptor: CARBONATE ION, FE (III) ION, LACTOFERRIN
Authors:Faber, H.R, Day, C.L, Baker, E.N.
Deposit date:1996-10-01
Release date:1997-04-21
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mutation of arginine 121 in lactoferrin destabilizes iron binding by disruption of anion binding: crystal structures of R121S and R121E mutants.
Biochemistry, 35, 1996
7R71
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BU of 7r71 by Molmil
Crystal Structure of the UbArk2C-UbcH5b~Ub complex
Descriptor: Ubiquitin, Ubiquitin,E3 ubiquitin-protein ligase RNF165, Ubiquitin-conjugating enzyme E2 D2, ...
Authors:Paluda, A, Middleton, A.J, Mace, P.D, Day, C.L.
Deposit date:2021-06-24
Release date:2022-03-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Ubiquitin and a charged loop regulate the ubiquitin E3 ligase activity of Ark2C.
Nat Commun, 13, 2022
7R70
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BU of 7r70 by Molmil
Crystal Structure of the UbArk2C fusion protein
Descriptor: GLYCEROL, Ubiquitin,E3 ubiquitin-protein ligase RNF165, ZINC ION
Authors:Paluda, A, Middleton, A.J, Mace, P.D, Day, C.L.
Deposit date:2021-06-24
Release date:2022-03-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.499 Å)
Cite:Ubiquitin and a charged loop regulate the ubiquitin E3 ligase activity of Ark2C.
Nat Commun, 13, 2022
4IC2
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BU of 4ic2 by Molmil
Crystal structure of the XIAP RING domain
Descriptor: E3 ubiquitin-protein ligase XIAP, NICKEL (II) ION, ZINC ION
Authors:Linke, K, Nakatani, Y, Day, C.L.
Deposit date:2012-12-09
Release date:2012-12-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Regulation of ubiquitin transfer by XIAP, a dimeric RING E3 ligase
Biochem.J., 450, 2013
4IC3
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BU of 4ic3 by Molmil
Crystal structure of the F495L mutant XIAP RING domain
Descriptor: E3 ubiquitin-protein ligase XIAP, NICKEL (II) ION, ZINC ION
Authors:Nakatani, Y, Day, C.L.
Deposit date:2012-12-09
Release date:2012-12-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.783 Å)
Cite:Regulation of ubiquitin transfer by XIAP, a dimeric RING E3 ligase
Biochem.J., 450, 2013
6W9D
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BU of 6w9d by Molmil
RNF12 RING domain in complex with a Ube2d2~Ub conjugate
Descriptor: E3 ubiquitin-protein ligase RLIM, IODIDE ION, Ubiquitin, ...
Authors:Middleton, A.J, Day, C.L.
Deposit date:2020-03-22
Release date:2020-05-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:The RING Domain of RING Finger 12 Efficiently Builds Degradative Ubiquitin Chains.
J.Mol.Biol., 432, 2020
6W7Z
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BU of 6w7z by Molmil
RNF12 RING domain in complex with Ube2d2
Descriptor: E3 ubiquitin-protein ligase RLIM, GLYCEROL, Ubiquitin-conjugating enzyme E2 D2, ...
Authors:Middleton, A.J, Day, C.L.
Deposit date:2020-03-19
Release date:2020-05-20
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The RING Domain of RING Finger 12 Efficiently Builds Degradative Ubiquitin Chains.
J.Mol.Biol., 432, 2020
6W9A
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BU of 6w9a by Molmil
RNF12 RING domain in complex with Ube2e2
Descriptor: E3 ubiquitin-protein ligase RLIM, GLYCEROL, Ubiquitin-conjugating enzyme E2 E2, ...
Authors:Middleton, A.J, Day, C.L.
Deposit date:2020-03-22
Release date:2020-05-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The RING Domain of RING Finger 12 Efficiently Builds Degradative Ubiquitin Chains.
J.Mol.Biol., 432, 2020
7L3L
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BU of 7l3l by Molmil
Structure of TRAF5 and TRAF6 RING Hetero dimer
Descriptor: TNF receptor-associated factor 5, TNF receptor-associated factor 6, ZINC ION
Authors:Das, A, Middleton, A.J, Padala, P, Day, C.L.
Deposit date:2020-12-17
Release date:2021-02-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structure and ubiquitin binding properties of TRAF RING heterodimers.
J.Mol.Biol., 2021
7MYH
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BU of 7myh by Molmil
Ubiquitin variant UbV.k.2 in complex with Ube2k
Descriptor: GLYCEROL, Ubiquitin variant UbV.k.2, Ubiquitin-conjugating enzyme E2 K
Authors:Middleton, A.J, Day, C.L, Teyra, J, Sidhu, S.S.
Deposit date:2021-05-21
Release date:2021-08-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.394 Å)
Cite:Identification of Ubiquitin Variants That Inhibit the E2 Ubiquitin Conjugating Enzyme, Ube2k.
Acs Chem.Biol., 16, 2021
7MYF
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BU of 7myf by Molmil
Ubiquitin variant UbV.k.1 in complex with Ube2k
Descriptor: Ubiquitin, Ubiquitin variant UbV.k.1, Ubiquitin-conjugating enzyme E2 K
Authors:Middleton, A.J, Day, C.L, Teyra, J, Sidhu, S.S.
Deposit date:2021-05-21
Release date:2021-08-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Identification of Ubiquitin Variants That Inhibit the E2 Ubiquitin Conjugating Enzyme, Ube2k.
Acs Chem.Biol., 16, 2021
1O0L
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BU of 1o0l by Molmil
THE STRUCTURE OF BCL-W REVEALS A ROLE FOR THE C-TERMINAL RESIDUES IN MODULATING BIOLOGICAL ACTIVITY
Descriptor: Apoptosis regulator Bcl-W
Authors:Hinds, M.G, Lackmann, M, Skea, G.L, Harrison, P.J, Huang, D.C.S, Day, C.L.
Deposit date:2003-02-22
Release date:2003-04-01
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:The structure of Bcl-w reveals a role for the C-terminal residues in modulating biological activity
Embo J., 22, 2003
1QBH
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BU of 1qbh by Molmil
SOLUTION STRUCTURE OF A BACULOVIRAL INHIBITOR OF APOPTOSIS (IAP) REPEAT
Descriptor: INHIBITOR OF APOPTOSIS PROTEIN (2MIHB/C-IAP-1), ZINC ION
Authors:Hinds, M.G, Norton, R.S, Vaux, D.L, Day, C.L.
Deposit date:1999-04-20
Release date:1999-10-20
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure of a baculoviral inhibitor of apoptosis (IAP) repeat.
Nat.Struct.Biol., 6, 1999
3EB6
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BU of 3eb6 by Molmil
Structure of the cIAP2 RING domain bound to UbcH5b
Descriptor: Baculoviral IAP repeat-containing protein 3, Ubiquitin-conjugating enzyme E2 D2, ZINC ION
Authors:Mace, P.D, Linke, K, Schumacher, F.-R, Smith, C.A, Day, C.L.
Deposit date:2008-08-27
Release date:2008-09-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structures of the cIAP2 RING Domain Reveal Conformational Changes Associated with Ubiquitin-conjugating Enzyme (E2) Recruitment.
J.Biol.Chem., 283, 2008

 

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