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1O7C
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BU of 1o7c by Molmil
Solution structure of the human TSG-6 Link module in the presence of a hyaluronan octasaccharide
Descriptor: TUMOR NECROSIS FACTOR-INDUCIBLE PROTEIN TSG-6
Authors:Blundell, C.D, Teriete, P, Kahmann, J.D, Pickford, A.R, Campbell, I.D, Day, A.J.
Deposit date:2002-10-29
Release date:2003-10-23
Last modified:2018-01-24
Method:SOLUTION NMR
Cite:The link module from ovulation- and inflammation-associated protein TSG-6 changes conformation on hyaluronan binding.
J. Biol. Chem., 278, 2003
1O7B
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BU of 1o7b by Molmil
Refined solution structure of the human TSG-6 Link module
Descriptor: TUMOR NECROSIS FACTOR-INDUCIBLE PROTEIN TSG-6
Authors:Blundell, C.D, Teriete, P, Kahmann, J.D, Pickford, A.R, Campbell, I.D, Day, A.J.
Deposit date:2002-10-29
Release date:2003-10-23
Last modified:2018-01-24
Method:SOLUTION NMR
Cite:The link module from ovulation- and inflammation-associated protein TSG-6 changes conformation on hyaluronan binding.
J. Biol. Chem., 278, 2003
1POZ
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BU of 1poz by Molmil
SOLUTION STRUCTURE OF THE HYALURONAN BINDING DOMAIN OF HUMAN CD44
Descriptor: CD44 antigen
Authors:Teriete, P, Banerji, S, Blundell, C.D, Kahmann, J.D, Pickford, A.R, Wright, A.J, Campbell, I.D, Jackson, D.G, Day, A.J.
Deposit date:2003-06-16
Release date:2004-03-16
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Structure of the Regulatory Hyaluronan Binding Domain in the Inflammatory Leukocyte Homing Receptor CD44.
Mol.Cell, 13, 2004
1AOT
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BU of 1aot by Molmil
NMR STRUCTURE OF THE FYN SH2 DOMAIN COMPLEXED WITH A PHOSPHOTYROSYL PEPTIDE, MINIMIZED AVERAGE STRUCTURE
Descriptor: FYN PROTEIN-TYROSINE KINASE, PHOSPHOTYROSYL PEPTIDE
Authors:Mulhern, T.D, Shaw, G.L, Morton, C.J, Day, A.J, Campbell, I.D.
Deposit date:1997-07-10
Release date:1998-01-14
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:The SH2 domain from the tyrosine kinase Fyn in complex with a phosphotyrosyl peptide reveals insights into domain stability and binding specificity.
Structure, 5, 1997
1AOU
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BU of 1aou by Molmil
NMR STRUCTURE OF THE FYN SH2 DOMAIN COMPLEXED WITH A PHOSPHOTYROSYL PEPTIDE, 22 STRUCTURES
Descriptor: FYN PROTEIN-TYROSINE KINASE, PHOSPHOTYROSYL PEPTIDE
Authors:Mulhern, T.D, Shaw, G.L, Morton, C.J, Day, A.J, Campbell, I.D.
Deposit date:1997-07-10
Release date:1998-01-14
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:The SH2 domain from the tyrosine kinase Fyn in complex with a phosphotyrosyl peptide reveals insights into domain stability and binding specificity.
Structure, 5, 1997
6FPZ
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BU of 6fpz by Molmil
Inter-alpha-inhibitor heavy chain 1, D298A
Descriptor: ACETATE ION, GLYCEROL, Inter-alpha-trypsin inhibitor heavy chain H1
Authors:Briggs, D.C, Day, A.J.
Deposit date:2018-02-12
Release date:2019-02-27
Last modified:2020-03-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Inter-alpha-inhibitor heavy chain-1 has an integrin-like 3D structure mediating immune regulatory activities and matrix stabilization during ovulation
J.Biol.Chem., 2020
6FPY
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BU of 6fpy by Molmil
Inter-alpha-inhibitor heavy chain 1, wild type
Descriptor: GLYCEROL, Inter-alpha-trypsin inhibitor heavy chain H1, MAGNESIUM ION
Authors:Briggs, D.C, Day, A.J.
Deposit date:2018-02-12
Release date:2019-02-27
Last modified:2020-03-18
Method:X-RAY DIFFRACTION (2.339 Å)
Cite:Inter-alpha-inhibitor heavy chain-1 has an integrin-like 3D structure mediating immune regulatory activities and matrix stabilization during ovulation
J.Biol.Chem., 2020
2PF5
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BU of 2pf5 by Molmil
Crystal Structure of the Human TSG-6 Link Module
Descriptor: NONAETHYLENE GLYCOL, SULFATE ION, Tumor necrosis factor-inducible protein TSG-6
Authors:Higman, V.A, Mahoney, D.J, Noble, M.E.M, Day, A.J.
Deposit date:2007-04-04
Release date:2007-06-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Plasticity of the TSG-6 HA-binding loop and mobility in the TSG-6-HA complex revealed by NMR and X-ray crystallography
J.Mol.Biol., 371, 2007
2JCQ
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BU of 2jcq by Molmil
The hyaluronan binding domain of murine CD44 in a Type A complex with an HA 8-mer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD44 ANTIGEN, GLYCEROL
Authors:Banerji, S, Wright, A.J, Noble, M.E.M, Mahoney, D.J, Campbell, I.D, Day, A.J, Jackson, D.G.
Deposit date:2007-01-03
Release date:2007-01-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structures of the Cd44-Hyaluronan Complex Provide Insight Into a Fundamental Carbohydrate-Protein Interaction.
Nat.Struct.Mol.Biol., 14, 2008
2JCR
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BU of 2jcr by Molmil
The hyaluronan binding domain of murine CD44 in a Type B complex with an HA 8-mer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD44 ANTIGEN, GLYCEROL
Authors:Banerji, S, Wright, A.J, Noble, M.E.M, Mahoney, D.J, Campbell, I.D, Day, A.J, Jackson, D.G.
Deposit date:2007-01-03
Release date:2007-01-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of the Cd44-Hyaluronan Complex Provide Insight Into a Fundamental Carbohydrate-Protein Interaction.
Nat.Struct.Mol.Biol., 14, 2008
2JCP
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BU of 2jcp by Molmil
The hyaluronan binding domain of murine CD44
Descriptor: CD44 ANTIGEN
Authors:Banerji, S, Wright, A.J, Noble, M.E.M, Mahoney, D.J, Campbell, I.D, Day, A.J, Jackson, D.G.
Deposit date:2007-01-03
Release date:2007-01-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structures of the Cd44-Hyaluronan Complex Provide Insight Into a Fundamental Carbohydrate-Protein Interaction.
Nat.Struct.Mol.Biol., 14, 2008
2UWN
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BU of 2uwn by Molmil
Crystal structure of Human Complement Factor H, SCR domains 6-8 (H402 risk variant), in complex with ligand.
Descriptor: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, ACETATE ION, CHLORIDE ION, ...
Authors:Prosser, B.E, Johnson, S, Roversi, P, Herbert, A.P, Blaum, B.S, Tyrrell, J, Jowitt, T.A, Clark, S.J, Terelli, E, Uhrin, D, Barlow, P.N, Sim, R.B, Day, A.J, Lea, S.M.
Deposit date:2007-03-22
Release date:2007-10-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Basis for Complement Factor H Linked Age-Related Macular Degeneration.
J.Exp.Med., 204, 2007
2V8E
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BU of 2v8e by Molmil
Crystal structure of Human Complement Factor H, SCR domains 6-8 (H402 risk variant), in complex with ligand.
Descriptor: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, CHLORIDE ION, COMPLEMENT FACTOR H, ...
Authors:Prosser, B.E, Johnson, S, Roversi, P, Herbert, A.P, Blaum, B.S, Tyrrell, J, Jowitt, T.A, Clark, S.J, Tarelli, E, Uhrin, D, Barlow, P.N, Sim, R.B, Day, A.J, Lea, S.M.
Deposit date:2007-08-07
Release date:2007-10-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Complement Factor H Linked Age-Related Macular Degeneration.
J.Exp.Med., 204, 2007
2WNO
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BU of 2wno by Molmil
X-ray Structure of CUB_C domain from TSG-6
Descriptor: CALCIUM ION, COBALT (II) ION, TUMOR NECROSIS FACTOR-INDUCIBLE GENE 6 PROTEIN
Authors:Briggs, D.C, Day, A.J.
Deposit date:2009-07-13
Release date:2010-09-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Metal Ion-Dependent Heavy Chain Transfer Activity of Tsg-6 Mediates Assembly of the Cumulus-Oocyte Matrix.
J.Biol.Chem., 290, 2015
2IC4
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BU of 2ic4 by Molmil
Solution structure of the His402 allotype of the Factor H SCR6-SCR7-SCR8 fragment
Descriptor: Complement factor H
Authors:Fernando, A.N, Furtado, P.B, Gilbert, H.E, Clark, S.J, Day, A.J, Sim, R.B, Perkins, S.J.
Deposit date:2006-09-12
Release date:2007-04-10
Last modified:2024-02-21
Method:SOLUTION SCATTERING
Cite:Associative and Structural Properties of the Region of Complement Factor H Encompassing the Tyr402His Disease-related Polymorphism and its Interactions with Heparin.
J.Mol.Biol., 368, 2007
1HCC
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BU of 1hcc by Molmil
THREE-DIMENSIONAL STRUCTURE OF A COMPLEMENT CONTROL PROTEIN MODULE IN SOLUTION
Descriptor: 16TH COMPLEMENT CONTROL PROTEIN
Authors:Norman, D.G, Barlow, P.B, Campbell, I.D.C.
Deposit date:1990-11-28
Release date:1992-04-15
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Three-dimensional structure of a complement control protein module in solution.
J.Mol.Biol., 219, 1991
2N40
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BU of 2n40 by Molmil
Solution structure of the link module of human tsg-6 in presence of a chondroitin 4-sulfate hexasaccharide
Descriptor: Tumor necrosis factor-inducible gene 6 protein
Authors:Park, Y, Prestegard, J.H.
Deposit date:2015-06-16
Release date:2016-01-13
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Nuclear Magnetic Resonance Insight into the Multiple Glycosaminoglycan Binding Modes of the Link Module from Human TSG-6.
Biochemistry, 55, 2016
4MRE
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BU of 4mre by Molmil
Crystal structure of the murine CD44 hyaluronan binding domain complex with a small molecule
Descriptor: 3-methylbenzene-1,2-diamine, CD44 antigen, DIMETHYL SULFOXIDE
Authors:Liu, L.K, Finzel, B.
Deposit date:2013-09-17
Release date:2014-04-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Fragment-Based Identification of an Inducible Binding Site on Cell Surface Receptor CD44 for the Design of Protein-Carbohydrate Interaction Inhibitors.
J.Med.Chem., 57, 2014
4MRD
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BU of 4mrd by Molmil
Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule
Descriptor: CD44 antigen, SULFATE ION, beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Liu, L.K, Finzel, B.
Deposit date:2013-09-17
Release date:2014-04-16
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Fragment-Based Identification of an Inducible Binding Site on Cell Surface Receptor CD44 for the Design of Protein-Carbohydrate Interaction Inhibitors.
J.Med.Chem., 57, 2014
4MRF
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BU of 4mrf by Molmil
Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule
Descriptor: 1,2,3,4-tetrahydroisoquinoline, CD44 antigen, DIMETHYL SULFOXIDE, ...
Authors:Liu, L.K, Finzel, B.
Deposit date:2013-09-17
Release date:2014-04-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Fragment-Based Identification of an Inducible Binding Site on Cell Surface Receptor CD44 for the Design of Protein-Carbohydrate Interaction Inhibitors.
J.Med.Chem., 57, 2014
4MRG
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BU of 4mrg by Molmil
Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule
Descriptor: 1,2,3,4-tetrahydroisoquinolin-5-amine, CD44 antigen, DIMETHYL SULFOXIDE, ...
Authors:Liu, L.K, Finzel, B.
Deposit date:2013-09-17
Release date:2014-04-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Fragment-Based Identification of an Inducible Binding Site on Cell Surface Receptor CD44 for the Design of Protein-Carbohydrate Interaction Inhibitors.
J.Med.Chem., 57, 2014
4MRH
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Crystal structure of the murine CD44 hyaluronan binding domain complex with a small molecule
Descriptor: 4-chloro-5-methylbenzene-1,2-diamine, CD44 antigen, DIMETHYL SULFOXIDE
Authors:Liu, L.K, Finzel, B.
Deposit date:2013-09-17
Release date:2014-04-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Fragment-Based Identification of an Inducible Binding Site on Cell Surface Receptor CD44 for the Design of Protein-Carbohydrate Interaction Inhibitors.
J.Med.Chem., 57, 2014

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