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6NZ0
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BU of 6nz0 by Molmil
Cryo-EM structure of AAV-2 in complex with AAVR PKD domains 1 and 2
Descriptor: Capsid protein VP1, Dyslexia-associated protein KIAA0319-like protein, MAGNESIUM ION
Authors:Meyer, N.L, Xie, Q, Davulcu, O, Yoshioka, C, Chapman, M.S.
Deposit date:2019-02-12
Release date:2019-06-12
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structure of the gene therapy vector, adeno-associated virus with its cell receptor, AAVR.
Elife, 8, 2019
8G6I
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BU of 8g6i by Molmil
Coagulation factor VIII bound to a patient-derived anti-C1 domain antibody inhibitor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Coagulation factor VIII chimera from human and pig, NB33 heavy chain, ...
Authors:Childers, K.C, Davulcu, O, Haynes, R.M, Lollar, P, Doering, C.B, Coxon, C.H, Spiegel, P.C.
Deposit date:2023-02-15
Release date:2023-05-24
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (4.23 Å)
Cite:Structure of coagulation factor VIII bound to a patient-derived anti-C1 domain antibody inhibitor.
Blood, 142, 2023
5UF6
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BU of 5uf6 by Molmil
The 2.8 A Electron Microscopy Structure of Adeno-Associated Virus-DJ Bound by a Heparanoid Pentasaccharide
Descriptor: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, capsid protein VP1
Authors:Xie, Q, Spear, J.M, Noble, A.J, Sousa, D.R, Meyer, N.L, Davulcu, O, Zhang, F, Linhardt, R.J, Stagg, S.M, Chapman, M.
Deposit date:2017-01-03
Release date:2017-05-24
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:The 2.8 angstrom Electron Microscopy Structure of Adeno-Associated Virus-DJ Bound by a Heparinoid Pentasaccharide.
Mol Ther Methods Clin Dev, 5, 2017
5J9A
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BU of 5j9a by Molmil
Ambient temperature transition state structure of arginine kinase - crystal 11/Form II
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ARGININE, Arginine kinase, ...
Authors:Godsey, M, Davulcu, O, Nix, J, Skalicky, J.J, Bruschweiler, R, Chapman, M.S.
Deposit date:2016-04-08
Release date:2016-08-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.997 Å)
Cite:The Sampling of Conformational Dynamics in Ambient-Temperature Crystal Structures of Arginine Kinase.
Structure, 24, 2016
5J99
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BU of 5j99 by Molmil
Ambient temperature transition state structure of arginine kinase - crystal 8/Form I
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ARGININE, Arginine kinase, ...
Authors:Godsey, M, Davulcu, O, Nix, J, Skalicky, J.J, Bruschweiler, R, Chapman, M.S.
Deposit date:2016-04-08
Release date:2016-08-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Sampling of Conformational Dynamics in Ambient-Temperature Crystal Structures of Arginine Kinase.
Structure, 24, 2016
4GVZ
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BU of 4gvz by Molmil
Crystal structure of arginine kinase in complex with D-arginine, MgADP, and nitrate.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Arginine kinase, D-ARGININE, ...
Authors:Clark, S.A, Davulcu, O, Chapman, M.S.
Deposit date:2012-08-31
Release date:2012-10-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Crystal structures of arginine kinase in complex with ADP, nitrate, and various phosphagen analogs.
Biochem.Biophys.Res.Commun., 427, 2012
4GW0
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BU of 4gw0 by Molmil
Crystal structure of arginine kinase in complex with imino-L-ornithine, MgADP, and nitrate.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Arginine kinase, MAGNESIUM ION, ...
Authors:Clark, S.A, Davulcu, O, Chapman, M.S.
Deposit date:2012-08-31
Release date:2012-10-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.448 Å)
Cite:Crystal structures of arginine kinase in complex with ADP, nitrate, and various phosphagen analogs.
Biochem.Biophys.Res.Commun., 427, 2012
4GW2
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BU of 4gw2 by Molmil
Crystal structure of arginine kinase in complex with L-ornithine, MgADP, and nitrate.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Arginine kinase, L-ornithine, ...
Authors:Clark, S.A, Davulcu, O, Chapman, M.S.
Deposit date:2012-08-31
Release date:2012-10-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.157 Å)
Cite:Crystal structures of arginine kinase in complex with ADP, nitrate, and various phosphagen analogs.
Biochem.Biophys.Res.Commun., 427, 2012
4GVY
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BU of 4gvy by Molmil
Crystal structure of arginine kinase in complex with L-citrulline and MgADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Arginine kinase, CITRULLINE, ...
Authors:Clark, S.A, Davulcu, O, Chapman, M.S.
Deposit date:2012-08-31
Release date:2012-10-03
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.091 Å)
Cite:Crystal structures of arginine kinase in complex with ADP, nitrate, and various phosphagen analogs.
Biochem.Biophys.Res.Commun., 427, 2012
8TY1
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BU of 8ty1 by Molmil
Cryo-EM structure of coagulation factor VIII bound to NB2E9
Descriptor: Coagulation factor VIII, NB2E9 heavy chain, NB2E9 light chain, ...
Authors:Childers, K.C, Spiegel, P.C.
Deposit date:2023-08-24
Release date:2023-09-13
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Structural basis for inhibition of coagulation factor VIII reveals a shared immunogenic hot-spot on the C1 domain
To Be Published
3JQ3
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BU of 3jq3 by Molmil
Crystal Structure of Lombricine Kinase, complexed with substrate ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lombricine kinase
Authors:Bush, D.J, Kirillova, O, Clark, S.A, Fabiola, F, Somasundaram, T, Chapman, M.S.
Deposit date:2009-09-05
Release date:2010-09-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.503 Å)
Cite:The structure of lombricine kinase: implications for phosphagen kinase conformational changes.
J.Biol.Chem., 286, 2011
3JPZ
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BU of 3jpz by Molmil
Crystal Structure of Lombricine Kinase
Descriptor: Lombricine kinase, NITRATE ION
Authors:Bush, D.J, Kirillova, O, Clark, S.A, Fabiola, F, Somasundaram, T, Chapman, M.S.
Deposit date:2009-09-04
Release date:2010-09-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The structure of lombricine kinase: implications for phosphagen kinase conformational changes.
J.Biol.Chem., 286, 2011
3M10
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BU of 3m10 by Molmil
Substrate-free form of Arginine Kinase
Descriptor: Arginine kinase, SULFATE ION
Authors:Yousef, M.S, Clark, S.A, Pruett, P.K, Somasundaram, T, Ellington, W.R, Chapman, M.S.
Deposit date:2010-03-03
Release date:2010-03-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.727 Å)
Cite:Arginine kinase: joint crystallographic and NMR RDC analyses link substrate-associated motions to intrinsic flexibility.
J.Mol.Biol., 405, 2011

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