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1RFF
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CRYSTAL STRUCTURE OF HUMAN TYROSYL-DNA PHOSPHODIESTERASE COMPLEXED WITH VANADATE, OCTAPEPTIDE KLNYYDPR, AND TETRANUCLEOTIDE AGTT.
分子名称:5'-D(*AP*GP*TP*T)-3', Tyrosyl-DNA phosphodiesterase 1, Topoisomerase I-Derived Peptide, ...
著者Davies, D.R., Interthal, H., Champoux, J.J., Hol, W.G.
登録日2003-11-08
公開日2004-03-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Explorations of peptide and oligonucleotide binding sites of tyrosyl-DNA phosphodiesterase using vanadate complexes.
J.Med.Chem., 47, 2004
1RFI
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CRYSTAL STRUCTURE OF HUMAN TYROSYL-DNA PHOSPHODIESTERASE COMPLEXED WITH VANADATE, PENTAPEPTIDE KLNYK, AND TETRANUCLEOTIDE AGTC
分子名称:5'-D(*AP*GP*TP*C)-3', Tyrosyl-DNA phosphodiesterase 1, Topoisomerase I-Derived Peptide, ...
著者Davies, D.R., Interthal, H., Champoux, J.J., Hol, W.G.
登録日2003-11-10
公開日2004-03-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Explorations of peptide and oligonucleotide binding sites of tyrosyl-DNA phosphodiesterase using vanadate complexes.
J.Med.Chem., 47, 2004
1RG1
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CRYSTAL STRUCTURE OF HUMAN TYROSYL-DNA PHOSPHODIESTERASE COMPLEXED WITH VANADATE, OCTOPAMINE, AND TETRANUCLEOTIDE AGTT
分子名称:5'-D(*AP*GP*TP*T)-3', Tyrosyl-DNA phosphodiesterase 1, VANADATE ION, ...
著者Davies, D.R., Interthal, H., Champoux, J.J., Hol, W.G.
登録日2003-11-10
公開日2004-03-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Explorations of peptide and oligonucleotide binding sites of tyrosyl-DNA phosphodiesterase using vanadate complexes.
J.Med.Chem., 47, 2004
1RG2
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CRYSTAL STRUCTURE OF HUMAN TYROSYL-DNA PHOSPHODIESTERASE COMPLEXED WITH VANADATE, OCTOPAMINE, AND TETRANUCLEOTIDE AGTA
分子名称:5'-D(*AP*GP*TP*A)-3', Tyrosyl-DNA phosphodiesterase 1, VANADATE ION, ...
著者Davies, D.R., Interthal, H., Champoux, J.J., Hol, W.G.
登録日2003-11-11
公開日2004-03-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Explorations of peptide and oligonucleotide binding sites of tyrosyl-DNA phosphodiesterase using vanadate complexes.
J.Med.Chem., 47, 2004
1RGT
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CRYSTAL STRUCTURE OF HUMAN TYROSYL-DNA PHOSPHODIESTERASE COMPLEXED WITH VANADATE, OCTOPAMINE, AND TETRANUCLEOTIDE AGTC
分子名称:5'-D(*AP*GP*TP*C)-3', Tyrosyl-DNA phosphodiesterase 1, VANADATE ION, ...
著者Davies, D.R., Interthal, H., Champoux, J.J., Hol, W.G.
登録日2003-11-12
公開日2004-03-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Explorations of peptide and oligonucleotide binding sites of tyrosyl-DNA phosphodiesterase using vanadate complexes.
J.Med.Chem., 47, 2004
1RGU
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THE CRYSTAL STRUCTURE OF HUMAN TYROSYL-DNA PHOSPHODIESTERASE COMPLEXED WITH VANADATE, OCTOPAMINE, AND TETRANUCLEOTIDE AGTG
分子名称:5'-D(*AP*GP*TP*G)-3', Tyrosyl-DNA phosphodiesterase 1, VANADATE ION, ...
著者Davies, D.R., Interthal, H., Champoux, J.J., Hol, W.G.
登録日2003-11-13
公開日2004-03-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Explorations of peptide and oligonucleotide binding sites of tyrosyl-DNA phosphodiesterase using vanadate complexes.
J.Med.Chem., 47, 2004
1RH0
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CRYSTAL STRUCTURE OF HUMAN TYROSYL-DNA PHOSPHODIESTERASE COMPLEXED WITH VANADATE, OCTOPAMINE AND TRINUCLEOTIDE GTT
分子名称:5'-D(*GP*TP*T)-3', Tyrosyl-DNA phosphodiesterase 1, VANADATE ION, ...
著者Davies, D.R., Interthal, H., Champoux, J.J., Hol, W.G.
登録日2003-11-13
公開日2004-03-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Explorations of peptide and oligonucleotide binding sites of tyrosyl-DNA phosphodiesterase using vanadate complexes.
J.Med.Chem., 47, 2004
1NOP
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CRYSTAL STRUCTURE OF HUMAN TYROSYL-DNA PHOSPHODIESTERASE (TDP1) IN COMPLEX WITH VANADATE, DNA AND A HUMAN TOPOISOMERASE I-DERIVED PEPTIDE
分子名称:5'-D(*AP*GP*AP*GP*TP*T)-3', tyrosyl-DNA phosphodiesterase 1, topoisomerase I-derived peptide, ...
著者Davies, D.R., Interthal, H., Champoux, J.J., Hol, W.G.J.
登録日2003-01-16
公開日2003-03-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a transition state mimic for Tdp1 assembled from vanadate, DNA, and a topoisomerase I-derived peptide
Chem.Biol., 10, 2003
1MU7
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CRYSTAL STRUCTURE OF A HUMAN TYROSYL-DNA PHOSPHODIESTERASE (TDP1)-TUNGSTATE COMPLEX
分子名称:Tyrosyl-DNA Phosphodiesterase, TUNGSTATE(VI)ION, GLYCEROL
著者Davies, D.R., Interthal, H., Champoux, J.J., Hol, W.G.J.
登録日2002-09-23
公開日2003-01-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insights Into Substrate Binding and Catalytic Mechanism of Human Tyrosyl-DNA Phosphodiesterase (Tdp1) from Vanadate- and Tungstate-Inhibited Structures
J.Mol.Biol., 324, 2003
1MU9
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CRYSTAL STRUCTURE OF A HUMAN TYROSYL-DNA PHOSPHODIESTERASE (TDP1)-VANADATE COMPLEX
分子名称:Tyrosyl-DNA Phosphodiesterase, VANADATE ION, GLYCEROL
著者Davies, D.R., Interthal, H., Champoux, J.J., Hol, W.G.J.
登録日2002-09-23
公開日2003-01-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Insights Into Substrate Binding and Catalytic Mechanism of Human Tyrosyl-DNA Phosphodiesterase (Tdp1) from Vanadate- and Tungstate-Inhibited Structures
J.Mol.Biol., 324, 2002
1B7E
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TRANSPOSASE INHIBITOR
分子名称:PROTEIN (TRANSPOSASE INHIBITOR PROTEIN FROM TN5), 2,2':6',2''-TERPYRIDINE PLATINUM(II) Chloride
著者Davies, D.R., Braam, L.M., Reznikoff, W.S., Rayment, I.
登録日1999-01-22
公開日1999-04-21
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The three-dimensional structure of a Tn5 transposase-related protein determined to 2.9A resolution.
J.Biol.Chem., 274, 1999
1JY1
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CRYSTAL STRUCTURE OF HUMAN TYROSYL-DNA PHOSPHODIESTERASE (TDP1)
分子名称:TYROSYL-DNA PHOSPHODIESTERASE
著者Davies, D.R., Interthal, H., Champoux, J.J., Hol, W.G.J.
登録日2001-09-10
公開日2002-02-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献The crystal structure of human tyrosyl-DNA phosphodiesterase, Tdp1.
Structure, 10, 2002
2B9S
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CRYSTAL STRUCTURE OF HETERODIMERIC L. DONOVANI TOPOISOMERASE I-VANADATE-DNA COMPLEX
分子名称:5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*T)-3', 5'-D(*AP*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', 5'-D(*AP*AP*AP*AP*AP*TP*TP*TP*TP*TP*CP*TP*AP*AP*GP*TP*CP*TP*TP*TP*TP*T)-3', ...
著者Davies, D.R., Hol, W.G.J.
登録日2005-10-12
公開日2006-01-17
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献The Structure of the Transition State of the Heterodimeric Topoisomerase I of Leishmania donovani as a Vanadate Complex with Nicked DNA.
J.Mol.Biol., 357, 2006
3FTS
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LEUKOTRIENE A4 HYDROLASE IN COMPLEX WITH RESVERATROL
分子名称:Leukotriene A-4 hydrolase, ZINC ION, YTTERBIUM (III) ION, ...
著者Davies, D.R.
登録日2009-01-13
公開日2009-07-28
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography.
J.Med.Chem., 52, 2009
3FTU
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LEUKOTRIENE A4 HYDROLASE IN COMPLEX WITH DIHYDRORESVERATROL
分子名称:Leukotriene A-4 hydrolase, ZINC ION, YTTERBIUM (III) ION, ...
著者Davies, D.R.
登録日2009-01-13
公開日2009-07-28
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography.
J.Med.Chem., 52, 2009
3FTV
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LEUKOTRIENE A4 HYDROLASE IN COMPLEX WITH FRAGMENT N-(PYRIDIN-3-YLMETHYL)ANILINE
分子名称:Leukotriene A-4 hydrolase, ZINC ION, YTTERBIUM (III) ION, ...
著者Davies, D.R.
登録日2009-01-13
公開日2009-07-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography.
J.Med.Chem., 52, 2009
3FTW
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LEUKOTRIENE A4 HYDROLASE IN COMPLEX WITH FRAGMENTS N-(PYRIDIN-3-YLMETHYL)ANILINE AND ACETATE
分子名称:Leukotriene A-4 hydrolase, ZINC ION, YTTERBIUM (III) ION, ...
著者Davies, D.R.
登録日2009-01-13
公開日2009-07-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography.
J.Med.Chem., 52, 2009
3FTX
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LEUKOTRIENE A4 HYDROLASE IN COMPLEX WITH DIHYDRORESVERATROL AND BESTATIN
分子名称:Leukotriene A-4 hydrolase, ZINC ION, YTTERBIUM (III) ION, ...
著者Davies, D.R.
登録日2009-01-13
公開日2009-07-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography.
J.Med.Chem., 52, 2009
3FTY
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LEUKOTRIENE A4 HYDROLASE IN COMPLEX WITH FRAGMENT 3-(BENZYLOXY)PYRIDIN-2-AMINE
分子名称:Leukotriene A-4 hydrolase, ZINC ION, YTTERBIUM (III) ION, ...
著者Davies, D.R.
登録日2009-01-13
公開日2009-07-28
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography.
J.Med.Chem., 52, 2009
3FU0
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LEUKOTRIENE A4 HYDROLASE IN COMPLEX WITH FRAGMENT 4-(4-FLUOROBENZOYL)PYRIDINE
分子名称:Leukotriene A-4 hydrolase, ZINC ION, YTTERBIUM (III) ION, ...
著者Davies, D.R.
登録日2009-01-13
公開日2009-07-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography.
J.Med.Chem., 52, 2009
3FU3
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LEUKOTRIENE A4 HYDROLASE IN COMPLEX WITH FRAGMENT 4-(2-AMINO-1,3-THIAZOL-4-YL)PHENOL
分子名称:Leukotriene A-4 hydrolase, ZINC ION, YTTERBIUM (III) ION, ...
著者Davies, D.R.
登録日2009-01-13
公開日2009-07-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography.
J.Med.Chem., 52, 2009
3FU5
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LEUKOTRIENE A4 HYDROLASE IN COMPLEX WITH (5-THIOPHEN-2-YLTHIOPHEN-2-YL)METHYLAMINE
分子名称:Leukotriene A-4 hydrolase, ZINC ION, YTTERBIUM (III) ION, ...
著者Davies, D.R.
登録日2009-01-14
公開日2009-07-28
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography.
J.Med.Chem., 52, 2009
3FU6
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LEUKOTRIENE A4 HYDROLASE IN COMPLEX WITH FRAGMENT (4-THIOPHEN-2-YLPHENYL)METHANAMINE
分子名称:Leukotriene A-4 hydrolase, ZINC ION, YTTERBIUM (III) ION, ...
著者Davies, D.R.
登録日2009-01-14
公開日2009-07-28
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography.
J.Med.Chem., 52, 2009
3FUD
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LEUKOTRIENE A4 HYDROLASE IN COMPLEX WITH N-METHYL-1-(2-THIOPHEN-2-YLPHENYL)METHANAMINE
分子名称:Leukotriene A-4 hydrolase, ZINC ION, YTTERBIUM (III) ION, ...
著者Davies, D.R.
登録日2009-01-14
公開日2009-07-28
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography.
J.Med.Chem., 52, 2009
3FUE
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LEUKOTRIENE A4 HYDROLASE IN COMPLEX WITH FRAGMENT 5-CHLOROINDOLE AND BESTATIN
分子名称:Leukotriene A-4 hydrolase, ZINC ION, YTTERBIUM (III) ION, ...
著者Davies, D.R.
登録日2009-01-14
公開日2009-07-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography.
J.Med.Chem., 52, 2009