Author results

6T9R
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APLYSIA CALIFORNICA ACHBP IN COMPLEX WITH A CYTISINE DERIVATIVE
Descriptor:Acetylcholine binding protein, (1~{R},9~{S})-5-(3-oxidanylpropyl)-7,11-diazatricyclo[7.3.1.0^{2,7}]trideca-2,4-dien-6-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Davis, S., Hunter, W.N.
Deposit date:2019-10-28
Release date:2020-02-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:The thermodynamic profile and molecular interactions of a C(9)-cytisine derivative-binding acetylcholine-binding protein from Aplysia californica.
Acta Crystallogr.,Sect.F, 76, 2020
6QKK
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APLYSIA CALIFORNICA ACHBP IN COMPLEX WITH 2-FLUORO-(CARBAMOYLPYRIDINYL)DESCHLOROEPIBATIDINE ANALOGUE (1)
Descriptor:Soluble acetylcholine receptor, 4-[5-[(1~{R},2~{R},4~{S})-7-azabicyclo[2.2.1]heptan-2-yl]-2-fluoranyl-pyridin-3-yl]benzamide, PHOSPHATE ION, ...
Authors:Davis, S., Bueno, R.V., Dawson, A., Hunter, W.N.
Deposit date:2019-01-29
Release date:2020-02-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Aplysia californica AChBP in complex with 2-Fluoro-(carbamoylpyridinyl)deschloroepibatidine analogue (1)
To Be Published
6ZDC
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STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN ENDO-ALPHA-MANNOSIDASE MANEA IN COMPLEX WITH NICKEL
Descriptor:Glycoprotein endo-alpha-1,2-mannosidase, NICKEL (II) ION
Authors:Sobala, L.F., Fernandes, P.Z., Hakki, Z., Thompson, A.J., Howe, J.D., Hill, M., Zitzmann, N., Davies, S., Stamataki, Z., Butters, T.D., Alonzi, D.S., Williams, S.J., Davies, G.J.
Deposit date:2020-06-14
Release date:2020-11-18
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (2.251 Å)
Cite:Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target.
Proc.Natl.Acad.Sci.USA, 117, 2020
6ZDF
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STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN ENDO-ALPHA-MANNOSIDASE MANEA IN COMPLEX WITH HEPES
Descriptor:Glycoprotein endo-alpha-1,2-mannosidase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Sobala, L.F., Fernandes, P.Z., Hakki, Z., Thompson, A.J., Howe, J.D., Hill, M., Zitzmann, N., Davies, S., Stamataki, Z., Butters, T.D., Alonzi, D.S., Williams, S.J., Davies, G.J.
Deposit date:2020-06-14
Release date:2020-11-18
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target.
Proc.Natl.Acad.Sci.USA, 117, 2020
6ZDK
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STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN ENDO-ALPHA-MANNOSIDASE MANEA IN COMPLEX WITH HEPES AND HEXATUNGSTOTELLURATE(VI) TEW
Descriptor:Glycoprotein endo-alpha-1,2-mannosidase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION, ...
Authors:Sobala, L.F., Fernandes, P.Z., Hakki, Z., Thompson, A.J., Howe, J.D., Hill, M., Zitzmann, N., Davies, S., Stamataki, Z., Butters, T.D., Alonzi, D.S., Williams, S.J., Davies, G.J.
Deposit date:2020-06-14
Release date:2020-11-18
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target.
Proc.Natl.Acad.Sci.USA, 117, 2020
6ZDL
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STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN ENDO-ALPHA-MANNOSIDASE MANEA IN COMPLEX WITH GLCIFG AND HEXATUNGSTOTELLURATE(VI) TEW
Descriptor:Glycoprotein endo-alpha-1,2-mannosidase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION, ...
Authors:Sobala, L.F., Fernandes, P.Z., Hakki, Z., Thompson, A.J., Howe, J.D., Hill, M., Zitzmann, N., Davies, S., Stamataki, Z., Butters, T.D., Alonzi, D.S., Williams, S.J., Davies, G.J.
Deposit date:2020-06-14
Release date:2020-11-18
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target.
Proc.Natl.Acad.Sci.USA, 117, 2020
6ZFA
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STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN ENDO-ALPHA-MANNOSIDASE MANEA IN COMPLEX WITH GLCIFG, ALPHA-1,2-MANNOBIOSE AND HEXATUNGSTOTELLURATE(VI) TEW
Descriptor:Glycoprotein endo-alpha-1,2-mannosidase, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Sobala, L.F., Fernandes, P.Z., Hakki, Z., Thompson, A.J., Howe, J.D., Hill, M., Zitzmann, N., Davies, S., Stamataki, Z., Butters, T.D., Alonzi, D.S., Williams, S.J., Davies, G.J.
Deposit date:2020-06-16
Release date:2020-11-18
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target.
Proc.Natl.Acad.Sci.USA, 117, 2020
6ZFN
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STRUCTURE OF AN INACTIVE E404Q VARIANT OF THE CATALYTIC DOMAIN OF HUMAN ENDO-ALPHA-MANNOSIDASE MANEA IN COMPLEX WITH 1-METHYL ALPHA-1,2-MANNOBIOSE
Descriptor:Glycoprotein endo-alpha-1,2-mannosidase, alpha-D-mannopyranose-(1-2)-methyl alpha-D-mannopyranoside, SULFATE ION
Authors:Sobala, L.F., Fernandes, P.Z., Hakki, Z., Thompson, A.J., Howe, J.D., Hill, M., Zitzmann, N., Davies, S., Stamataki, Z., Butters, T.D., Alonzi, D.S., Williams, S.J., Davies, G.J.
Deposit date:2020-06-17
Release date:2020-11-18
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target.
Proc.Natl.Acad.Sci.USA, 117, 2020
6ZFQ
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STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN ENDO-ALPHA-MANNOSIDASE MANEA IN COMPLEX WITH BIS-TRIS
Descriptor:Glycoprotein endo-alpha-1,2-mannosidase, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Sobala, L.F., Fernandes, P.Z., Hakki, Z., Thompson, A.J., Howe, J.D., Hill, M., Zitzmann, N., Davies, S., Stamataki, Z., Butters, T.D., Alonzi, D.S., Williams, S.J., Davies, G.J.
Deposit date:2020-06-17
Release date:2020-11-18
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target.
Proc.Natl.Acad.Sci.USA, 117, 2020
6ZJ1
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STRUCTURE OF AN INACTIVE E404Q VARIANT OF THE CATALYTIC DOMAIN OF HUMAN ENDO-ALPHA-MANNOSIDASE MANEA IN COMPLEX WITH TETRASACCHARIDE N-GLYCAN FRAGMENT AND HEXATUNGSTOTELLURATE(VI) TEW
Descriptor:Glycoprotein endo-alpha-1,2-mannosidase, alpha-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-methyl alpha-D-mannopyranoside, MAGNESIUM ION, ...
Authors:Sobala, L.F., Fernandes, P.Z., Hakki, Z., Thompson, A.J., Howe, J.D., Hill, M., Zitzmann, N., Davies, S., Stamataki, Z., Butters, T.D., Alonzi, D.S., Williams, S.J., Davies, G.J.
Deposit date:2020-06-27
Release date:2020-12-02
Method:X-RAY DIFFRACTION (1.957 Å)
Cite:Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target.
Proc.Natl.Acad.Sci.USA, 2020
6ZJ6
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STRUCTURE OF THE GH99 ENDO-ALPHA-MANNANASE FROM BACTEROIDES XYLANISOLVENS IN COMPLEX WITH CYCLOHEXYLMETHYL-GLC-1,3-ISOFAGOMINE
Descriptor:Glycosyl hydrolase family 71, 1,2-ETHANEDIOL, ACETATE ION, ...
Authors:Thompson, A.J., Sobala, L.F., Fernandes, P.Z., Hakki, Z., Howe, J.D., Hill, M., Zitzmann, N., Davies, S., Stamataki, Z., Butters, T.D., Alonzi, D.S., Williams, S.J., Davies, G.J.
Deposit date:2020-06-27
Release date:2020-11-18
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (1.09 Å)
Cite:Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target.
Proc.Natl.Acad.Sci.USA, 117, 2020
1R17
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CRYSTAL STRUCTURE ANALYSIS OF S.EPIDERMIDIS ADHESIN SDRG BINDING TO FIBRINOGEN (ADHESIN-LIGAND COMPLEX)
Descriptor:fibrinogen-binding protein SdrG, fibrinopeptide B, CALCIUM ION
Authors:Ponnuraj, K., Bowden, M.G., Davis, S., Gurusiddappa, S., Moore, D., Choe, D., Xu, Y., Hook, M., Narayana, S.V.L.
Deposit date:2003-09-23
Release date:2003-10-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:A "dock, lock and latch" Structural Model for a Staphylococcal Adhesin Binding to Fibrinogen
Cell(Cambridge,Mass.), 115, 2003
1R19
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CRYSTAL STRUCTURE ANALYSIS OF S.EPIDERMIDIS ADHESIN SDRG BINDING TO FIBRINOGEN (APO STRUCTURE)
Descriptor:fibrinogen-binding protein SdrG
Authors:Ponnuraj, K., Bowden, M.G., Davis, S., Gurusiddappa, S., Moore, D., Choe, D., Xu, Y., Hook, M., Narayana, S.V.L.
Deposit date:2003-09-23
Release date:2003-10-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.51 Å)
Cite:A "dock, lock and latch" Structural Model for a Staphylococcal Adhesin Binding to Fibrinogen
Cell(Cambridge,Mass.), 115, 2003
4ASZ
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CRYSTAL STRUCTURE OF APO TRKB KINASE DOMAIN
Descriptor:BDNF/NT-3 GROWTH FACTORS RECEPTOR
Authors:Bertrand, T., Kothe, M., Liu, J., Dupuy, A., Rak, A., Berne, P.F., Davis, S., Gladysheva, T., Valtre, C., Crenne, J.Y., Mathieu, M.
Deposit date:2012-05-03
Release date:2012-08-22
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Crystal Structures of Trka and Trkb Suggest Key Regions for Achieving Selective Inhibition.
J.Mol.Biol., 423, 2012
4AT3
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CRYSTAL STRUCTURE OF TRKB KINASE DOMAIN IN COMPLEX WITH CPD5N
Descriptor:BDNF/NT-3 GROWTH FACTORS RECEPTOR, (5Z)-5-(carbamoylimino)-3-[(5R)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ylsulfanyl]-2,5-dihydroisothiazole-4-carboxamide
Authors:Bertrand, T., Kothe, M., Liu, J., Dupuy, A., Rak, A., Berne, P.F., Davis, S., Gladysheva, T., Valtre, C., Crenne, J.Y., Mathieu, M.
Deposit date:2012-05-03
Release date:2012-08-22
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:The Crystal Structures of Trka and Trkb Suggest Key Regions for Achieving Selective Inhibition.
J.Mol.Biol., 423, 2012
4AT4
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CRYSTAL STRUCTURE OF TRKB KINASE DOMAIN IN COMPLEX WITH EX429
Descriptor:BDNF/NT-3 GROWTH FACTORS RECEPTOR, 1-[4-(4-aminothieno[2,3-d]pyrimidin-5-yl)phenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Authors:Bertrand, T., Kothe, M., Liu, J., Dupuy, A., Rak, A., Berne, P.F., Davis, S., Gladysheva, T., Valtre, C., Crenne, J.Y., Mathieu, M.
Deposit date:2012-05-03
Release date:2012-08-22
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:The Crystal Structures of Trka and Trkb Suggest Key Regions for Achieving Selective Inhibition.
J.Mol.Biol., 423, 2012
4AT5
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CRYSTAL STRUCTURE OF TRKB KINASE DOMAIN IN COMPLEX WITH GW2580
Descriptor:BDNF/NT-3 GROWTH FACTORS RECEPTOR, 5-{3-methoxy-4-[(4-methoxybenzyl)oxy]benzyl}pyrimidine-2,4-diamine, GLYCEROL
Authors:Bertrand, T., Kothe, M., Liu, J., Dupuy, A., Rak, A., Berne, P.F., Davis, S., Gladysheva, T., Valtre, C., Crenne, J.Y., Mathieu, M.
Deposit date:2012-05-03
Release date:2012-08-22
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:The Crystal Structures of Trka and Trkb Suggest Key Regions for Achieving Selective Inhibition.
J.Mol.Biol., 423, 2012
6QQO
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APLYSIA CALIFORNICA ACHBP IN COMPLEX WITH 2-FLUORO-(CARBAMOYLPYRIDINYL)DESCHLOROEPIBATIDINE ANALOGUE (3)
Descriptor:Soluble acetylcholine receptor, 6-[5-[(1~{R},2~{R},4~{S})-7-azabicyclo[2.2.1]heptan-2-yl]-2-fluoranyl-pyridin-3-yl]pyridine-3-carboxamide, PHOSPHATE ION, ...
Authors:Bueno, R.V., Davis, S., Dawson, A., Hunter, W.N.
Deposit date:2019-02-18
Release date:2020-03-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Aplysia californica AChBP in complex with 2-Fluoro-(carbamoylpyridinyl)deschloroepibatidine analogues
To Be Published
6QQP
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APLYSIA CALIFORNICA ACHBP IN COMPLEX WITH 2-FLUORO-(CARBAMOYLPYRIDINYL)DESCHLOROEPIBATIDINE ANALOGUE (2)
Descriptor:Soluble acetylcholine receptor, 2-[5-[(1~{R},2~{R},4~{S})-7-azabicyclo[2.2.1]heptan-2-yl]-2-fluoranyl-pyridin-3-yl]pyridine-4-carboxamide, 1,2-ETHANEDIOL, ...
Authors:Bueno, R.V., Davis, S., Dawson, A., Hunter, W.N.
Deposit date:2019-02-18
Release date:2020-03-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Aplysia californica AChBP in complex with 2-Fluoro-(carbamoylpyridinyl)deschloroepibatidine analogues
To Be Published
1BL0
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MULTIPLE ANTIBIOTIC RESISTANCE PROTEIN (MARA)/DNA COMPLEX
Descriptor:DNA (5'-D(*GP*GP*GP*GP*AP*TP*TP*TP*AP*GP*CP*AP*AP*AP*AP*CP*GP*TP*GP*GP*CP*AP* TP*C)-3'), DNA (5'-D(*CP*CP*GP*AP*TP*GP*CP*CP*AP*CP*GP*TP*TP*TP*TP*GP*CP*TP*AP*AP*AP*TP* CP*C)-3'), PROTEIN (MULTIPLE ANTIBIOTIC RESISTANCE PROTEIN)
Authors:Davies, S., Rhee, R.G., Martin, J.L., Rosner, D.R.
Deposit date:1998-07-22
Release date:1998-09-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A novel DNA-binding motif in MarA: the first structure for an AraC family transcriptional activator.
Proc.Natl.Acad.Sci.USA, 95, 1998
2MCP
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REFINED CRYSTAL STRUCTURE OF THE MC/PC603 FAB-PHOSPHOCHOLINE COMPLEX AT 3.1 ANGSTROMS RESOLUTION
Descriptor:IGA-KAPPA MCPC603 FAB (LIGHT CHAIN), IGA-KAPPA MCPC603 FAB (HEAVY CHAIN), PHOSPHOCHOLINE
Authors:Padlan, E.A., Cohen, G.H., Davies, D.R.
Deposit date:1984-10-15
Release date:1985-01-02
Last modified:2017-02-08
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Refined Crystal Structure of the Mc/Pc603 Fab-Phosphocholine Complex at 3.1 Angstroms Resolution
To be Published
5NFN
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JMJD7 IN COMPLEX WITH MN AND 2OG IN THE H32 FORM
Descriptor:JmjC domain-containing protein 7, MANGANESE (II) ION, 2-OXOGLUTARIC ACID, ...
Authors:Chowdhury, R., Markolovic, S., Schofield, C.J.
Deposit date:2017-03-14
Release date:2018-03-14
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (2.982 Å)
Cite:(3S)-Lysyl hydroxylation of TRAFAC GTPases is catalyzed by the human Jumonji-C oxygenase JMJD7.
To Be Published
5NFO
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HUMAN JMJD7 IN COMPLEX WITH MN AND 2OG IN THE P21212 FORM
Descriptor:JmjC domain-containing protein 7, MANGANESE (II) ION, 2-OXOGLUTARIC ACID, ...
Authors:Chowdhury, R., Markolovic, S., Schofield, C.J.
Deposit date:2017-03-14
Release date:2018-03-14
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (2.173 Å)
Cite:(3S)-Lysyl hydroxylation of TRAFAC GTPases is catalyzed by the human Jumonji-C oxygenase JMJD7.
To Be Published
4F0I
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CRYSTAL STRUCTURE OF APO TRKA
Descriptor:High affinity nerve growth factor receptor
Authors:Liu, J.
Deposit date:2012-05-04
Release date:2012-09-05
Last modified:2012-11-14
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:The Crystal Structures of TrkA and TrkB Suggest Key Regions for Achieving Selective Inhibition.
J.Mol.Biol., 423, 2012
171916
PDB entries from 2020-12-02