4D2H
 
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6H86
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8OWI
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8R2G
 | | Crystal structure of a BRCA2-DMC1 complex | | Descriptor: | Breast cancer type 2 susceptibility protein, Meiotic recombination protein DMC1/LIM15 homolog | | Authors: | Dunce, J.M, Davies, O.R. | | Deposit date: | 2023-11-05 | | Release date: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.45 Å) | | Cite: | Crystal structure of a BRCA2-DMC1 complex
To Be Published
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7Z8Y
 | | Crystal structure of the SUN1-KASH6 9:6 complex | | Descriptor: | CHLORIDE ION, Inositol 1,4,5-triphosphate receptor associated 2, POTASSIUM ION, ... | | Authors: | Gurusaran, M, Davies, O.R. | | Deposit date: | 2022-03-19 | | Release date: | 2023-09-27 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | The crystal structure of SUN1-KASH6 reveals an asymmetric LINC complex architecture compatible with nuclear membrane insertion.
Commun Biol, 7, 2024
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7Z8Z
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8AU0
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8B5X
 | | Crystal structure of the SUN1-KASH6 9:6 complex | | Descriptor: | CHLORIDE ION, Inositol 1,4,5-triphosphate receptor associated 2, POTASSIUM ION, ... | | Authors: | Erlandsen, B.S, Gurusaran, M, Davies, O.R. | | Deposit date: | 2022-09-25 | | Release date: | 2023-10-04 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | The crystal structure of SUN1-KASH6 reveals an asymmetric LINC complex architecture compatible with nuclear membrane insertion.
Commun Biol, 7, 2024
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8B46
 | | Crystal structure of the SUN1-KASH6 9:9 complex | | Descriptor: | CHLORIDE ION, Inositol 1,4,5-triphosphate receptor associated 2, POTASSIUM ION, ... | | Authors: | Gurusaran, M, Erlandsen, B.S, Davies, O.R. | | Deposit date: | 2022-09-19 | | Release date: | 2023-09-27 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | The crystal structure of SUN1-KASH6 reveals an asymmetric LINC complex architecture compatible with nuclear membrane insertion.
Commun Biol, 7, 2024
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6YQF
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1Z56
 | | Co-Crystal Structure of Lif1p-Lig4p | | Descriptor: | DNA ligase IV, Ligase interacting factor 1 | | Authors: | Dore, A.S, Furnham, N, Davies, O.R, Sibanda, B.L, Chirgadze, D.Y, Jackson, S.P, Pellegrini, L, Blundell, T.L. | | Deposit date: | 2005-03-17 | | Release date: | 2006-01-31 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.92 Å) | | Cite: | Structure of an Xrcc4-DNA ligase IV yeast ortholog complex reveals a novel BRCT interaction mode.
DNA REPAIR, 5, 2006
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2WVI
 | | Crystal Structure of the N-terminal Domain of BubR1 | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 BETA, ... | | Authors: | D'Arcy, S, Davies, O.R, Blundell, T.L, Bolanos-Garcia, V.M. | | Deposit date: | 2009-10-16 | | Release date: | 2010-03-09 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Defining the Molecular Basis of Bubr1 Kinetochore Interactions and Anaphase-Promoting Complex/Cyclosome (Apc/C)-Cdc20 Inhibition
J.Biol.Chem., 285, 2010
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2QM4
 | | Crystal structure of human XLF/Cernunnos, a non-homologous end-joining factor | | Descriptor: | Non-homologous end-joining factor 1 | | Authors: | Li, Y, Chirgadze, D.Y, Sibanda, B.L, Bolanos-Garcia, V.M, Davies, O.R, Blundell, T.L. | | Deposit date: | 2007-07-14 | | Release date: | 2007-12-11 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ.
Embo J., 27, 2008
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6HK8
 | | Crystal structure of TEX12 delta-Ctip | | Descriptor: | 1,4-DIETHYLENE DIOXIDE, Testis-expressed protein 12 | | Authors: | Salmon, L.J, Davies, O.R. | | Deposit date: | 2018-09-06 | | Release date: | 2019-10-16 | | Method: | X-RAY DIFFRACTION (2.111 Å) | | Cite: | Synaptonemal complex central element extension through hierarchical assembly of SYCE2-TEX12 into alpha-fibres
To Be Published
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6HK9
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4CPC
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6F62
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6F64
 | | Crystal structure of the SYCP1 C-terminal back-to-back assembly | | Descriptor: | ACETATE ION, Synaptonemal complex protein 1 | | Authors: | Dunce, J.M, Millan, C, Uson, I, Davies, O.R. | | Deposit date: | 2017-12-04 | | Release date: | 2018-06-06 | | Last modified: | 2020-04-22 | | Method: | X-RAY DIFFRACTION (2.493 Å) | | Cite: | Structural basis of meiotic chromosome synapsis through SYCP1 self-assembly.
Nat. Struct. Mol. Biol., 25, 2018
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6F63
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6F5X
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6GNX
 | | Crystal structure of the MAJIN-TERB2 heterotetrameric complex - selenomethionine derivative | | Descriptor: | Membrane-anchored junction protein, Telomere repeats-binding bouquet formation protein 2 | | Authors: | Gurusaran, M, Dunce, J.M, Sen, L.T, Davies, O.R. | | Deposit date: | 2018-06-01 | | Release date: | 2018-12-12 | | Last modified: | 2020-04-22 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural basis of meiotic telomere attachment to the nuclear envelope by MAJIN-TERB2-TERB1.
Nat Commun, 9, 2018
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6GNY
 | | Crystal structure of the MAJIN-TERB2 heterotetrameric complex | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Membrane-anchored junction protein, Telomere repeats-binding bouquet formation protein 2 | | Authors: | Dunce, J.M, Gurusaran, M, Sen, L.T, Davies, O.R. | | Deposit date: | 2018-06-01 | | Release date: | 2018-12-12 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural basis of meiotic telomere attachment to the nuclear envelope by MAJIN-TERB2-TERB1.
Nat Commun, 9, 2018
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6R2F
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6R2I
 | | Crystal structure of the SUN1-KASH5 6:6 complex | | Descriptor: | KASH5, POTASSIUM ION, SUN domain-containing protein 1 | | Authors: | Gurusaran, M, Davies, O.R. | | Deposit date: | 2019-03-18 | | Release date: | 2020-07-15 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.541 Å) | | Cite: | A molecular mechanism for LINC complex branching by structurally diverse SUN-KASH 6:6 assemblies.
Elife, 10, 2021
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6R17
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