Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
6EZH
DownloadVisualize
BU of 6ezh by Molmil
Torpedo californica AChE in complex with indolic multi-target directed ligand
Descriptor: 1-(7-chloranyl-4-methoxy-1~{H}-indol-5-yl)-3-[1-(cyclohexylmethyl)piperidin-4-yl]propan-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase
Authors:Santoni, G, Lalut, J, Karila, D, Lecoutey, C, Davis, A, Nachon, F, Sillman, I, Sussman, J, Weik, M, Maurice, T, Dallemagne, P, Rochais, C.
Deposit date:2017-11-15
Release date:2018-11-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Novel multitarget-directed ligands targeting acetylcholinesterase and sigma1receptors as lead compounds for treatment of Alzheimer's disease: Synthesis, evaluation, and structural characterization of their complexes with acetylcholinesterase.
Eur J Med Chem, 162, 2018
6EZG
DownloadVisualize
BU of 6ezg by Molmil
Torpedo californica AChE in complex with indolic multi-target directed ligand
Descriptor: 1-(7-chloranyl-4-methoxy-1~{H}-indol-5-yl)-3-[1-(phenylmethyl)piperidin-4-yl]propan-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, ...
Authors:Santoni, G, Lalut, J, Karila, D, Lecoutey, C, Davis, A, Nachon, F, Sillman, I, Sussman, J, Weik, M, Maurice, T, Dallemagne, P, Rochais, C.
Deposit date:2017-11-15
Release date:2018-11-21
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Novel multitarget-directed ligands targeting acetylcholinesterase and sigma1receptors as lead compounds for treatment of Alzheimer's disease: Synthesis, evaluation, and structural characterization of their complexes with acetylcholinesterase.
Eur J Med Chem, 162, 2018
4O8W
DownloadVisualize
BU of 4o8w by Molmil
Crystal Structure of the GerD spore germination protein
Descriptor: Spore germination protein
Authors:Li, Y, Jin, K, Ghosh, S, Devarakonda, P, Carlson, K, Davis, A, Stewart, K, Cammett, E, Rossi, P.P, Setlow, B, Lu, M, Setlow, P, Hao, B.
Deposit date:2013-12-30
Release date:2014-03-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.293 Å)
Cite:Structural and Functional Analysis of the GerD Spore Germination Protein of Bacillus Species.
J.Mol.Biol., 426, 2014
1KI2
DownloadVisualize
BU of 1ki2 by Molmil
CRYSTAL STRUCTURE OF THYMIDINE KINASE FROM HERPES SIMPLEX VIRUS TYPE I COMPLEXED WITH GANCICLOVIR
Descriptor: 9-(1,3-DIHYDROXY-PROPOXYMETHANE)GUANINE, SULFATE ION, THYMIDINE KINASE
Authors:Champness, J.N, Bennett, M.S, Wien, F, Brown, D.G, Visse, R, Sandhu, G, Davies, A, Rizkallah, P.J, Melitz, C, Summers, W.C, Sanderson, M.R.
Deposit date:1998-05-15
Release date:1998-12-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands.
Proteins, 32, 1998
1KIM
DownloadVisualize
BU of 1kim by Molmil
CRYSTAL STRUCTURE OF THYMIDINE KINASE FROM HERPES SIMPLEX VIRUS TYPE I COMPLEXED WITH DEOXYTHYMIDINE
Descriptor: SULFATE ION, THYMIDINE, THYMIDINE KINASE
Authors:Champness, J.N, Bennett, M.S, Wien, F, Brown, D.G, Visse, R, Sandhu, G, Davies, A, Rizkallah, P.J, Melitz, C, Summers, W.C, Sanderson, M.R.
Deposit date:1997-11-12
Release date:1998-05-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands.
Proteins, 32, 1998
6E5C
DownloadVisualize
BU of 6e5c by Molmil
Solution NMR structure of a de novo designed double-stranded beta-helix
Descriptor: De novo beta protein
Authors:Marcos, E, Chidyausiku, T.M, McShan, A, Evangelidis, T, Nerli, S, Sgourakis, N, Tripsianes, K, Baker, D.
Deposit date:2018-07-19
Release date:2018-11-07
Last modified:2018-11-14
Method:SOLUTION NMR
Cite:De novo design of a non-local beta-sheet protein with high stability and accuracy.
Nat. Struct. Mol. Biol., 25, 2018
6O59
DownloadVisualize
BU of 6o59 by Molmil
Crystal structure of the N-terminal domain of the A subunit of the Bacillus megaterium spore germinant receptor GerK3
Descriptor: Germination protein
Authors:Li, Y, Hao, B.
Deposit date:2019-03-01
Release date:2019-05-22
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structural and functional analyses of the N-terminal domain of the A subunit of aBacillus megateriumspore germinant receptor.
Proc.Natl.Acad.Sci.USA, 116, 2019
1CDR
DownloadVisualize
BU of 1cdr by Molmil
STRUCTURE OF A SOLUBLE, GLYCOSYLATED FORM OF THE HUMAN COMPLEMENT REGULATORY PROTEIN CD59
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CD59
Authors:Fletcher, C.M, Harrison, R.A, Lachmann, P.J, Neuhaus, D.
Deposit date:1994-06-01
Release date:1994-09-30
Last modified:2020-07-29
Method:SOLUTION NMR
Cite:Structure of a soluble, glycosylated form of the human complement regulatory protein CD59.
Structure, 2, 1994
1CDS
DownloadVisualize
BU of 1cds by Molmil
STRUCTURE OF A SOLUBLE, GLYCOSYLATED FORM OF THE HUMAN COMPLEMENT REGULATORY PROTEIN CD59
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD59
Authors:Fletcher, C.M, Harrison, R.A, Lachmann, P.J, Neuhaus, D.
Deposit date:1994-06-01
Release date:1994-09-30
Last modified:2020-07-29
Method:SOLUTION NMR
Cite:Structure of a soluble, glycosylated form of the human complement regulatory protein CD59.
Structure, 2, 1994
1RGD
DownloadVisualize
BU of 1rgd by Molmil
STRUCTURE REFINEMENT OF THE GLUCOCORTICOID RECEPTOR-DNA BINDING DOMAIN FROM NMR DATA BY RELAXATION MATRIX CALCULATIONS
Descriptor: GLUCOCORTICOID RECEPTOR, ZINC ION
Authors:Van Tilborg, M.A.A, Bonvin, A.M.J.J, Hard, K, Davis, A, Maler, B, Boelens, R, Yamamoto, K.R, Kaptein, R.
Deposit date:1995-01-06
Release date:1995-02-14
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structure refinement of the glucocorticoid receptor-DNA binding domain from NMR data by relaxation matrix calculations.
J.Mol.Biol., 247, 1995
1DBF
DownloadVisualize
BU of 1dbf by Molmil
CHORISMATE MUTASE FROM BACILLUS SUBTILIS AT 1.30 ANGSTROM
Descriptor: GLYCEROL, PROTEIN (CHORISMATE MUTASE), SULFATE ION
Authors:Gilliland, G.L, Ladner, J.E.
Deposit date:1999-11-02
Release date:2000-06-07
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The 1.30 A resolution structure of the Bacillus subtilis chorismate mutase catalytic homotrimer.
Acta Crystallogr.,Sect.D, 56, 2000
7SKN
DownloadVisualize
BU of 7skn by Molmil
De novo synthetic protein DIG8-CC (tetragonal space group)
Descriptor: De novo synthetic protein DIG8-CC
Authors:Mendes, S.R, Eckhard, U, Marcos, E, Gomis-Ruth, F.X.
Deposit date:2021-10-21
Release date:2022-10-12
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:De novo design of immunoglobulin-like domains
Nat Commun, 13, 2022
7SKO
DownloadVisualize
BU of 7sko by Molmil
De novo synthetic protein DIG8-CC (orthogonal space group)
Descriptor: De novo synthetic protein DIG8-CC, MAGNESIUM ION
Authors:Mendes, S.R, Eckhard, U, Marcos, E, Gomis-Ruth, F.X.
Deposit date:2021-10-21
Release date:2022-10-12
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:De novo design of immunoglobulin-like domains
Nat Commun, 13, 2022
7SKP
DownloadVisualize
BU of 7skp by Molmil
De novo synthetic protein DIG14 (tetragonal space group)
Descriptor: De novo synthetic protein DIG14
Authors:Mendes, S.R, Eckhard, U, Marcos, E, Gomis-Ruth, F.X.
Deposit date:2021-10-21
Release date:2022-10-12
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:De novo design of immunoglobulin-like domains
Nat Commun, 13, 2022
1E2H
DownloadVisualize
BU of 1e2h by Molmil
The nucleoside binding site of Herpes simplex type 1 thymidine kinase analyzed by X-ray crystallography
Descriptor: SULFATE ION, THYMIDINE KINASE
Authors:Vogt, J, Scapozza, L, Schulz, G.E.
Deposit date:2000-05-23
Release date:2000-11-06
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Nucleoside Binding Site of Herpes Simplex Type 1 Thymidine Kinase Analyzed by X-Ray Crystallography
Proteins: Struct.,Funct., Genet., 41, 2000
1E2I
DownloadVisualize
BU of 1e2i by Molmil
The nucleoside binding site of Herpes simplex type 1 thymidine kinase analyzed by X-ray crystallography
Descriptor: 9-HYDROXYPROPYLADENINE, R-ISOMER, S-ISOMER, ...
Authors:Vogt, J, Scapozza, L, Schulz, G.E.
Deposit date:2000-05-23
Release date:2000-11-06
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Nucleoside Binding Site of Herpes Simplex Type 1 Thymidine Kinase Analyzed by X-Ray Crystallography
Proteins, 41, 2000
1E2J
DownloadVisualize
BU of 1e2j by Molmil
The nucleoside binding site of Herpes simplex type 1 thymidine kinase analyzed by X-ray crystallography
Descriptor: SULFATE ION, THYMIDINE, THYMIDINE KINASE
Authors:Vogt, J, Scapozza, L, Schulz, G.E.
Deposit date:2000-05-23
Release date:2000-11-06
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Nucleoside Binding Site of Herpes Simplex Type 1 Thymidine Kinase Analyzed by X-Ray Crystallography
Proteins: Struct.,Funct., Genet., 41, 2000
3F0T
DownloadVisualize
BU of 3f0t by Molmil
Crystal structure of thymidine kinase from Herpes simplex virus type 1 in complex with N-methyl-DHBT
Descriptor: N-Methyl-6-(1,3-dihydroxy-isobutyl)thymine, SULFATE ION, Thymidine kinase
Authors:Pernot, L, Perozzo, R, Westermaier, Y, Martic, M, Ametamey, S, Scapozza, L.
Deposit date:2008-10-26
Release date:2009-11-03
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Synthesis, crystal structure, and in vitro biological evaluation of C-6 pyrimidine derivatives: new lead structures for monitoring gene expression in vivo.
Nucleosides Nucleotides Nucleic Acids, 30, 2011
1E2K
DownloadVisualize
BU of 1e2k by Molmil
Kinetics and crystal structure of the wild-type and the engineered Y101F mutant of Herpes simplex virus type 1 thymidine kinase interacting with (North)-methanocarba-thymidine
Descriptor: 1-[4-HYDROXY-5-(HYDROXYMETHYL)BICYCLO[3.1.0]HEX-2-YL]-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE, SULFATE ION, THYMIDINE KINASE
Authors:Vogt, J, Scapozza, L, Schulz, G.E.
Deposit date:2000-05-23
Release date:2000-08-19
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Kinetics and Crystal Structure of the Wild-Type and the Engineered Y101F Mutant of Herpes Simplex Virus Type 1 Thymidine Kinase Interacting with (North)-Methanocarba-Thymidine
Biochemistry, 39, 2000
1E2L
DownloadVisualize
BU of 1e2l by Molmil
Kinetics and crystal structure of the wild-type and the engineered Y101F mutant of Herpes simplex virus type 1 thymidine kinase interacting with (North)-methanocarba-thymidine
Descriptor: 1-[4-HYDROXY-5-(HYDROXYMETHYL)BICYCLO[3.1.0]HEX-2-YL]-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE, SULFATE ION, THYMIDINE KINASE
Authors:Vogt, J, Scapozza, L, Schulz, G.E.
Deposit date:2000-05-23
Release date:2000-08-18
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Kinetics and Crystal Structure of the Wild-Type and the Engineered Y101F Mutant of Herpes Simplex Virus Type 1 Thymidine Kinase Interacting with (North)-Methanocarba-Thymidine
Biochemistry, 39, 2000
2F6L
DownloadVisualize
BU of 2f6l by Molmil
X-ray structure of Chorismate Mutase from Mycobacterium Tuberculosis
Descriptor: Chorismate mutase
Authors:Kim, S.K, Howard, A.J, Gilliland, G.L, Reddy, P.T, Ladner, J.E.
Deposit date:2005-11-29
Release date:2005-12-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Biochemical and structural characterization of the secreted chorismate mutase (Rv1885c) from Mycobacterium tuberculosis H37Rv: an *AroQ enzyme not regulated by the aromatic amino acids.
J.Bacteriol., 188, 2006
1E2N
DownloadVisualize
BU of 1e2n by Molmil
HPT + HMTT
Descriptor: 6-{[4-(HYDROXYMETHYL)-5-METHYL-2,6-DIOXOHEXAHYDROPYRIMIDIN-5-YL]METHYL}-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE, SULFATE ION, THYMIDINE KINASE
Authors:Vogt, J, Scapozza, L, Schulz, G.E.
Deposit date:2000-05-23
Release date:2001-03-31
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Effect of Substrate Binding on the Conformation and Structural Stability of Herpes Simplex Virus Type 1 Thymidine Kinase
Protein Sci., 10, 2001
1E2M
DownloadVisualize
BU of 1e2m by Molmil
HPT + HMTT
Descriptor: 6-HYDROXYPROPYLTHYMINE, SULFATE ION, THYMIDINE KINASE
Authors:Vogt, J, Scapozza, L, Schulz, G.E.
Deposit date:2000-05-23
Release date:2001-03-31
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Effect of Substrate Binding on the Conformation and Structural Stability of Herpes Simplex Virus Type 1 Thymidine Kinase
Protein Sci., 10, 2001
1KI3
DownloadVisualize
BU of 1ki3 by Molmil
CRYSTAL STRUCTURE OF THYMIDINE KINASE FROM HERPES SIMPLEX VIRUS TYPE I COMPLEXED WITH PENCICLOVIR
Descriptor: 9-(4-HYDROXY-3-(HYDROXYMETHYL)BUT-1-YL)GUANINE, SULFATE ION, THYMIDINE KINASE
Authors:Champness, J.N, Bennett, M.S, Wien, F, Visse, R, Jarvest, R.L, Summers, W.C, Sanderson, M.R.
Deposit date:1998-05-15
Release date:1999-05-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands.
Proteins, 32, 1998
1KI7
DownloadVisualize
BU of 1ki7 by Molmil
CRYSTAL STRUCTURE OF THYMIDINE KINASE FROM HERPES SIMPLEX VIRUS TYPE I COMPLEXED WITH 5-IODODEOXYURIDINE
Descriptor: 5-IODODEOXYURIDINE, SULFATE ION, THYMIDINE KINASE
Authors:Champness, J.N, Bennett, M.S, Wien, F, Visse, R, Summers, W.C, Sanderson, M.R.
Deposit date:1998-05-15
Release date:1998-12-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands.
Proteins, 32, 1998

 

12>

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon