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1TD6
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CRYSTAL STRUCTURE OF THE CONSERVED HYPOTHETICAL PROTEIN MP506/MPN330 (GI: 1674200)FROM MYCOPLASMA PNEUMONIAE
Descriptor:Hypothetical protein MG237 homolog
Authors:Das, D., Oganesyan, N., Yokota, H., Jancarik, J., Kim, R., Kim, S.H., Berkeley Structural Genomics Center (BSGC)
Deposit date:2004-05-21
Release date:2004-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the conserved hypothetical protein MPN330 (GI: 1674200) from Mycoplasma pneumoniae.
Proteins, 58, 2004
2AQ0
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SOLUTION STRUCTURE OF THE HUMAN HOMODIMERIC DNA REPAIR PROTEIN XPF
Descriptor:DNA repair endonuclease XPF
Authors:Das, D., Tripsianes, K., Folkers, G., Jaspers, N.G., Hoeijmakers, J.H., Kaptein, R., Boelens, R.
Deposit date:2005-08-17
Release date:2006-10-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The HhH domain of the human DNA repair protein XPF forms stable homodimers
Proteins, 70, 2008
2HQL
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CRYSTAL STRUCTURE OF A SMALL SINGLE-STRANDED DNA BINDING PROTEIN FROM MYCOPLASMA PNEUMONIAE
Descriptor:Hypothetical protein MG376 homolog
Authors:Das, D., Berkeley Structural Genomics Center (BSGC)
Deposit date:2006-07-18
Release date:2007-05-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a novel single-stranded DNA binding protein from Mycoplasma pneumoniae.
Proteins, 67, 2007
2I6W
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CRYSTAL STRUCTURE OF THE MULTIDRUG EFFLUX TRANSPORTER ACRB
Descriptor:Acriflavine resistance protein B
Authors:Das, D., Xu, Q.S., Kim, S.H.
Deposit date:2006-08-29
Release date:2007-05-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of the multidrug efflux transporter AcrB at 3.1A resolution reveals the N-terminal region with conserved amino acids.
J.Struct.Biol., 158, 2007
2KN7
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STRUCTURE OF THE XPF-SINGLE STRAND DNA COMPLEX
Descriptor:DNA repair endonuclease XPF, DNA (5'-D(*CP*AP*GP*TP*GP*GP*CP*TP*GP*A)-3')
Authors:Das, D., Folkers, G.E., van Dijk, M., Jaspers, N.G.J., Hoeijmakers, J.H.J., Kaptein, R., Boelens, R.
Deposit date:2009-08-16
Release date:2010-08-04
Last modified:2012-07-04
Method:SOLUTION NMR
Cite:The structure of the XPF-ssDNA complex underscores the distinct roles of the XPF and ERCC1 helix- hairpin-helix domains in ss/ds DNA recognition
Structure, 20, 2012
4MH8
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THE CRYSTAL STRUCTURE OF THE MONOMERIC REVERSE TRANSCRIPTASE FROM MOLONEY MURINE LEUKEMIA VIRUS
Descriptor:Reverse transcriptase/ribonuclease H p80
Authors:Das, D., Georgiadis, M.M.
Deposit date:2013-08-29
Release date:2013-10-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:The crystal structure of the monomeric reverse transcriptase from Moloney murine leukemia virus.
Structure, 12, 2004
4KVQ
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CRYSTAL STRUCTURE OF PROCHLOROCOCCUS MARINUS ALDEHYDE-DEFORMYLATING OXYGENASE WILD TYPE WITH PALMITIC ACID BOUND
Descriptor:Aldehyde decarbonylase, FE (III) ION, PALMITIC ACID
Authors:Levy, C.W., Khara, B., Menon, N., Mansell, D., Das, D., Marsh, E.N.G., Leys, D., Scrutton, N.S.
Deposit date:2013-05-23
Release date:2013-06-26
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (1.842 Å)
Cite:Production of propane and other short-chain alkanes by structure-based engineering of ligand specificity in aldehyde-deformylating oxygenase.
Chembiochem, 14, 2013
4KVR
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CRYSTAL STRUCTURE OF PROCHLOROCOCCUS MARINUS ALDEHYDE-DEFORMYLATING OXYGENASE (MUTANT V41Y)
Descriptor:Aldehyde decarbonylase, HEXANOIC ACID, FE (III) ION
Authors:Levy, C.W., Khara, B., Menon, N., Mansell, D., Das, D., Marsh, E.N.G., Leys, D., Scrutton, N.S.
Deposit date:2013-05-23
Release date:2013-06-26
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Production of propane and other short-chain alkanes by structure-based engineering of ligand specificity in aldehyde-deformylating oxygenase.
Chembiochem, 14, 2013
4KVS
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CRYSTAL STRUCTURE OF PROCHLOROCOCCUS MARINUS ALDEHYDE-DEFORMYLATING OXYGENASE (MUTANT A134F)
Descriptor:Aldehyde decarbonylase, HEXANOIC ACID, FE (III) ION
Authors:Levy, C.W., Khara, B., Menon, N., Mansell, D., Das, D., Marsh, E.N.G., Leys, D., Scrutton, N.S.
Deposit date:2013-05-23
Release date:2013-06-26
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Production of propane and other short-chain alkanes by structure-based engineering of ligand specificity in aldehyde-deformylating oxygenase.
Chembiochem, 14, 2013
3H98
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CRYSTAL STRUCTURE OF HCV NS5B 1B WITH (1,1-DIOXO-2H-[1,2,4]BENZOTHIADIAZIN-3-YL) AZOLO[1,5-A]PYRIMIDINE DERIVATIVE
Descriptor:RNA-directed RNA polymerase, N-{3-[5-hydroxy-8-(3-methylbutyl)-7-oxo-7,8-dihydroimidazo[1,2-a]pyrimidin-6-yl]-1,1-dioxido-4H-1,2,4-benzothiadiazin-7-yl}methanesulfonamide, GLYCEROL
Authors:Wang, G., Lei, H., Wang, X., Das, D., Mackinnon, C., Montalbetti, C.A.G., Mears, R., Gai, X., Bailey, S., Ruhrmund, D., Hooi, L., Misialek, S., Rajagopalan, R., Cheng, R.K.Y., Barker, J.L., Felicetti, B., Stoycheva, A., Buckman, B., Kossen, K., Seiwert, S., Beigelmana, L.
Deposit date:2009-04-30
Release date:2009-10-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:HCV NS5B polymerase inhibitors 2: Synthesis and in vitro activity of (1,1-dioxo-2H-[1,2,4]benzothiadiazin-3-yl) azolo[1,5-a]pyridine and azolo[1,5-a]pyrimidine derivatives.
Bioorg.Med.Chem.Lett., 19, 2009
1NND
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ARGININE 116 IS ESSENTIAL FOR NUCLEIC ACID RECOGNITION BY THE FINGERS DOMAIN OF MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE
Descriptor:Reverse Transcriptase
Authors:Crowther, R.L., Remeta, D.P., Minetti, C.A., Das, D., Montano, S.P., Georgiadis, M.M.
Deposit date:2003-01-13
Release date:2004-01-27
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and energetic characterization of nucleic acid-binding to the fingers domain of Moloney murine leukemia virus reverse transcriptase
Proteins, 57, 2004
1Z00
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SOLUTION STRUCTURE OF THE C-TERMINAL DOMAIN OF ERCC1 COMPLEXED WITH THE C-TERMINAL DOMAIN OF XPF
Descriptor:DNA excision repair protein ERCC-1, DNA repair endonuclease XPF
Authors:Tripsianes, K., Folkers, G., Ab, E., Das, D., Odijk, H., Jaspers, N.G.J., Hoeijmakers, J.H.J., Kaptein, R., Boelens, R.
Deposit date:2005-03-01
Release date:2005-12-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The Structure of the Human ERCC1/XPF Interaction Domains Reveals a Complementary Role for the Two Proteins in Nucleotide Excision Repair
Structure, 13, 2005
2BJC
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NMR STRUCTURE OF A PROTEIN-DNA COMPLEX OF AN ALTERED SPECIFICITY MUTANT OF THE LAC REPRESSOR HEADPIECE THAT MIMICS THE GAL REPRESSOR
Descriptor:LACTOSE OPERON REPRESSOR, 5'-D(*GP*AP*AP*TP*TP*GP*TP*AP*AP*GP *CP*GP*CP*TP*TP*AP*CP*AP*AP*TP*TP*C)-3'
Authors:Salinas, R.K., Folkers, G.E., Bonvin, A.M.J.J., Das, D., Boelens, R., Kaptein, R.
Deposit date:2005-02-01
Release date:2005-10-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Altered Specificity in DNA Binding by the Lac Repressor: A Mutant Lac Headpiece that Mimics the Gal Repressor
Chembiochem, 6, 2005
2JPD
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SOLUTION STRUCTURE OF THE ERCC1 CENTRAL DOMAIN
Descriptor:DNA excision repair protein ERCC-1
Authors:Tripsianes, K., Folkers, G., Zheng, C., Das, D., Grinstead, J.S., Kaptein, R., Boelens, R.
Deposit date:2007-05-06
Release date:2007-09-04
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Analysis of the XPA and ssDNA-binding surfaces on the central domain of human ERCC1 reveals evidence for subfunctionalization
Nucleic Acids Res., 35, 2007
2Y4W
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SOLUTION STRUCTURE OF HUMAN UBIQUITIN CONJUGATING ENZYME RAD6B
Descriptor:UBIQUITIN-CONJUGATING ENZYME E2 B
Authors:Huang, A., Hibbert, R.G., deJong, R.N., Das, D., Sixma, T.K., Boelens, R.
Deposit date:2011-01-11
Release date:2011-05-11
Last modified:2012-06-27
Method:SOLUTION NMR
Cite:Symmetry and Asymmetry of the Ring-Ring Dimer of Rad18
J.Mol.Biol., 410, 2011
4HLA
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CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH DARUNAVIR
Descriptor:Protease, (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE
Authors:Yedidi, R.S., Garimella, H., Palmer, I., Das, D., Wingfield, P.T., Ghosh, A.K., Mitsuya, H.
Deposit date:2012-10-16
Release date:2013-07-24
Last modified:2013-09-25
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:P2' benzene carboxylic acid moiety is associated with decrease in cellular uptake: evaluation of novel non-peptidic HIV-1 protease inhibitors containing P2 bis-tetrahydrofuran moiety.
Antimicrob.Agents Chemother., 57, 2013
4I8W
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CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH NON-PEPTIDIC INHIBITOR, GRL007
Descriptor:Protease, 4-{[(2R,3S)-3-({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yloxy]carbonyl}amino)-2-hydroxy-4-phenylbutyl](2-methylpropyl)sulfamoyl}benzoic acid
Authors:Yedidi, R.S., Palmer, I., Das, D., Wingfield, P.T., Ghosh, A.K., Mitsuya, H.
Deposit date:2012-12-04
Release date:2013-07-24
Last modified:2013-09-25
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:P2' benzene carboxylic acid moiety is associated with decrease in cellular uptake: evaluation of novel non-peptidic HIV-1 protease inhibitors containing P2 bis-tetrahydrofuran moiety.
Antimicrob.Agents Chemother., 57, 2013
4I8Z
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CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH NON-PEPTIDIC INHIBITOR, GRL008
Descriptor:Protease, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{[(4-carbamoylphenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate
Authors:Yedidi, R.S., Palmer, I., Das, D., Wingfield, P.T., Ghosh, A.K., Mitsuya, H.
Deposit date:2012-12-04
Release date:2013-07-24
Last modified:2013-09-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:P2' benzene carboxylic acid moiety is associated with decrease in cellular uptake: evaluation of novel non-peptidic HIV-1 protease inhibitors containing P2 bis-tetrahydrofuran moiety.
Antimicrob.Agents Chemother., 57, 2013
4NJS
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CRYSTAL STRUCTURE OF MULTIDRUG-RESISTANT CLINICAL ISOLATE A02 HIV-1 PROTEASE IN COMPLEX WITH NON-PEPTIDIC INHIBITOR, GRL008
Descriptor:Protease, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{[(4-carbamoylphenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate
Authors:Yedidi, R.S., Garimella, H., Kaufman, J.D., Das, D., Wingfield, P.T., Ghosh, A.K., Mitsuya, H.
Deposit date:2013-11-11
Release date:2014-04-02
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Conserved Hydrogen-Bonding Network of P2 bis-Tetrahydrofuran-Containing HIV-1 Protease Inhibitors (PIs) with a Protease Active-Site Amino Acid Backbone Aids in Their Activity against PI-Resistant HIV.
Antimicrob.Agents Chemother., 58, 2014
4NJT
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CRYSTAL STRUCTURE OF MULTIDRUG-RESISTANT CLINICAL ISOLATE A02 HIV-1 PROTEASE IN COMPLEX WITH DARUNAVIR
Descriptor:Protease, (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE
Authors:Yedidi, R.S., Garimella, H., Chang, S.B., Kaufman, J.D., Das, D., Wingfield, P.T., Ghosh, A.K., Mitsuya, H.
Deposit date:2013-11-11
Release date:2014-04-02
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A Conserved Hydrogen-Bonding Network of P2 bis-Tetrahydrofuran-Containing HIV-1 Protease Inhibitors (PIs) with a Protease Active-Site Amino Acid Backbone Aids in Their Activity against PI-Resistant HIV.
Antimicrob.Agents Chemother., 58, 2014
4NJU
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CRYSTAL STRUCTURE OF MULTIDRUG-RESISTANT CLINICAL ISOLATE A02 HIV-1 PROTEASE IN COMPLEX WITH TIPRANAVIR
Descriptor:Protease, N-(3-{(1R)-1-[(6R)-4-HYDROXY-2-OXO-6-PHENETHYL-6-PROPYL-5,6-DIHYDRO-2H-PYRAN-3-YL]PROPYL}PHENYL)-5-(TRIFLUOROMETHYL)-2-PYRIDINESULFONAMIDE
Authors:Yedidi, R.S., Garimella, H., Kaufman, J.D., Das, D., Wingfield, P.T., Mitsuya, H.
Deposit date:2013-11-11
Release date:2014-04-02
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Conserved Hydrogen-Bonding Network of P2 bis-Tetrahydrofuran-Containing HIV-1 Protease Inhibitors (PIs) with a Protease Active-Site Amino Acid Backbone Aids in Their Activity against PI-Resistant HIV.
Antimicrob.Agents Chemother., 58, 2014
4NJV
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CRYSTAL STRUCTURE OF MULTIDRUG-RESISTANT CLINICAL ISOLATE A02 HIV-1 PROTEASE IN COMPLEX WITH RITONAVIR
Descriptor:Protease, RITONAVIR
Authors:Yedidi, R.S., Garimella, H., Chang, S.B., Kaufman, J.D., Das, D., Wingfield, P.T., Mitsuya, H.
Deposit date:2013-11-11
Release date:2014-04-02
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Conserved Hydrogen-Bonding Network of P2 bis-Tetrahydrofuran-Containing HIV-1 Protease Inhibitors (PIs) with a Protease Active-Site Amino Acid Backbone Aids in Their Activity against PI-Resistant HIV.
Antimicrob.Agents Chemother., 58, 2014
4PG0
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INSIGHTS INTO SUBSTRATE AND METAL BINDING FROM THE CRYSTAL STRUCTURE OF CYANOBACTERIAL ALDEHYDE DEFORMYLATING OXYGENASE WITH SUBSTRATE BOUND
Descriptor:Aldehyde decarbonylase, FE (III) ION, (1S,2S)-2-nonylcyclopropanecarboxylic acid, ...
Authors:Buer, B.C., Paul, B., Das, D., Stuckey, J.A., Marsh, E.N.G.
Deposit date:2014-05-01
Release date:2014-11-26
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Insights into substrate and metal binding from the crystal structure of cyanobacterial aldehyde deformylating oxygenase with substrate bound.
Acs Chem.Biol., 9, 2014
4PG1
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INSIGHTS INTO SUBSTRATE AND METAL BINDING FROM THE CRYSTAL STRUCTURE OF CYANOBACTERIAL ALDEHYDE DEFORMYLATING OXYGENASE WITH SUBSTRATE BOUND
Descriptor:Aldehyde decarbonylase, FE (III) ION, (1S,2S)-2-nonylcyclopropanecarboxylic acid, ...
Authors:Buer, B.C., Paul, B., Das, D., Stuckey, J.A., Marsh, E.N.G.
Deposit date:2014-05-01
Release date:2014-11-19
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Insights into substrate and metal binding from the crystal structure of cyanobacterial aldehyde deformylating oxygenase with substrate bound.
Acs Chem.Biol., 9, 2014
4PGI
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INSIGHTS INTO SUBSTRATE AND METAL BINDING FROM THE CRYSTAL STRUCTURE OF CYANOBACTERIAL ALDEHYDE DEFORMYLATING OXYGENASE WITH SUBSTRATE ANALOGS BOUND
Descriptor:Aldehyde decarbonylase, FE (III) ION, 11-[2-(2-ethoxyethoxy)ethoxy]undecanal, ...
Authors:Buer, B.C., Paul, B., Das, D., Stuckey, J.A., Marsh, E.N.G.
Deposit date:2014-05-02
Release date:2015-02-11
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Insights into substrate and metal binding from the crystal structure of cyanobacterial aldehyde deformylating oxygenase with substrate bound.
Acs Chem.Biol., 9, 2014