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6PIR
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BU of 6pir by Molmil
Crystal structure of the Legionella effector protein MavE
Descriptor: CITRIC ACID, MavE
Authors:Cygler, M, Voth, K.A.
Deposit date:2019-06-26
Release date:2020-05-06
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of the Legionella effector MavE
To Be Published
6OMI
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BU of 6omi by Molmil
Crystal structure of the Legionella effector protein MavL
Descriptor: BROMIDE ION, MavL
Authors:Cygler, M, Voth, K.
Deposit date:2019-04-18
Release date:2020-02-26
Method:X-RAY DIFFRACTION (2.643 Å)
Cite:Crystal Structure of the Legionella Effector protein MavL
To Be Published
1MIR
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BU of 1mir by Molmil
RAT PROCATHEPSIN B
Descriptor: PROCATHEPSIN B
Authors:Cygler, M, Sivaraman, J, Grochulski, P, Coulombe, R, Storer, A.C, Mort, J.S.
Deposit date:1996-01-12
Release date:1997-01-11
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of rat procathepsin B: model for inhibition of cysteine protease activity by the proregion.
Structure, 4, 1996
1MFE
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BU of 1mfe by Molmil
RECOGNITION OF A CELL-SURFACE OLIGO-SACCHARIDE OF PATHOGENIC SALMONELLA BY AN ANTIBODY FAB FRAGMENT
Descriptor: IGG1-LAMBDA SE155-4 FAB (HEAVY CHAIN), IGG1-LAMBDA SE155-4 FAB (LIGHT CHAIN), alpha-D-galactopyranose-(1-2)-[alpha-D-Abequopyranose-(1-3)]alpha-D-mannopyranose
Authors:Cygler, M.
Deposit date:1993-10-25
Release date:1994-01-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Recognition of a cell-surface oligosaccharide of pathogenic Salmonella by an antibody Fab fragment.
Science, 253, 1991
1AJ5
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BU of 1aj5 by Molmil
CALPAIN DOMAIN VI APO
Descriptor: CALPAIN
Authors:Cygler, M, Grochulski, P, Blanchard, H.
Deposit date:1997-05-15
Release date:1998-05-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of a calpain Ca(2+)-binding domain reveals a novel EF-hand and Ca(2+)-induced conformational changes.
Nat.Struct.Biol., 4, 1997
4Q5E
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BU of 4q5e by Molmil
Shigella Effector Kinase OspG bound to E2-Ub UbcH7-Ub Conjugate
Descriptor: Polyubiquitin, Protein kinase OspG, Ubiquitin-conjugating enzyme E2 L3
Authors:Cygler, M, Grishin, A.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2014-04-16
Release date:2014-07-02
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.869 Å)
Cite:Structural Basis for the Inhibition of Host Protein Ubiquitination by Shigella Effector Kinase OspG.
Structure, 22, 2014
7KJ6
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BU of 7kj6 by Molmil
Structure of Legionella Effector LegA15
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Ankyrin repeat-containing protein, CHLORIDE ION, ...
Authors:Cygler, M, Chung, I.Y.W.
Deposit date:2020-10-26
Release date:2021-08-18
Last modified:2021-12-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Legionella effector LegA15/AnkH contains an unrecognized cysteine protease-like domain and displays structural similarity to LegA3/AnkD, but differs in host cell localization.
Acta Crystallogr D Struct Biol, 77, 2021
4II4
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BU of 4ii4 by Molmil
The Phenylacetyl-CoA monooxygenase - mutant PaaA E49Q K68Q - PaaC wild type subcomplex with benzoyl-CoA
Descriptor: 1,2-phenylacetyl-CoA epoxidase, subunit A, subunit C, ...
Authors:Cygler, M, Grishin, A.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2012-12-19
Release date:2014-08-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.799 Å)
Cite:Spatial Organization of Subunits within the Phenylacetyl-CoA Monooxygenase Complex
To be published
4IIT
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BU of 4iit by Molmil
The Phenylacetyl-CoA monooxygenase PaaABC subcomplex with phenylacetyl-CoA
Descriptor: Phenylacetate-CoA oxygenase subunit PaaA, Phenylacetate-CoA oxygenase subunit PaaB, Phenylacetate-CoA oxygenase subunit PaaC, ...
Authors:Cygler, M, Grishin, A.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2012-12-20
Release date:2013-11-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Family of phenylacetyl-CoA monooxygenases differs in subunit organization from other monooxygenases.
J.Struct.Biol., 184, 2013
6WO6
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BU of 6wo6 by Molmil
Structure of RavA (lpp0008) E38A/K39A surface entropy reduction mutant
Descriptor: RavA
Authors:Cygler, M, Chung, I.Y.W.
Deposit date:2020-04-24
Release date:2021-03-17
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and functional study of Legionella pneumophila effector RavA.
Protein Sci., 30, 2021
6MCA
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BU of 6mca by Molmil
Structure of Legionella Effector AnkH
Descriptor: Ankyrin repeat domain protein, GLYCEROL, L(+)-TARTARIC ACID
Authors:Cygler, M, Chung, I.Y.W.
Deposit date:2018-08-30
Release date:2019-09-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.455 Å)
Cite:Interaction of the Ankyrin H Core Effector ofLegionellawith the Host LARP7 Component of the 7SK snRNP Complex.
Mbio, 10, 2019
4LRJ
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BU of 4lrj by Molmil
Bacterial Effector NleH1 Kinase Domain with AMPPNP and Mg2+
Descriptor: Effector NleH1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Cygler, M, Grishin, A.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2013-07-19
Release date:2014-01-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.619 Å)
Cite:NleH defines a new family of bacterial effector kinases.
Structure, 22, 2014
4LRK
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BU of 4lrk by Molmil
Bacterial Effector NleH2 Kinase Domain
Descriptor: Effector NleH2
Authors:Cygler, M, Grishin, A.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2013-07-19
Release date:2014-01-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.274 Å)
Cite:NleH defines a new family of bacterial effector kinases.
Structure, 22, 2014
4Q5H
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BU of 4q5h by Molmil
Shigella Effector Kinase OspG bound to AMPPNP and E2-Ub UbcH7-Ub Conjugate
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Polyubiquitin, ...
Authors:Cygler, M, Grishin, A.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2014-04-16
Release date:2014-07-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Structural Basis for the Inhibition of Host Protein Ubiquitination by Shigella Effector Kinase OspG.
Structure, 22, 2014
1CS8
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BU of 1cs8 by Molmil
CRYSTAL STRUCTURE OF PROCATHEPSIN L
Descriptor: HUMAN PROCATHEPSIN L
Authors:Cygler, M, Coulombe, R.
Deposit date:1999-08-17
Release date:1999-08-23
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment.
EMBO J., 15, 1996
1DVI
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BU of 1dvi by Molmil
CALPAIN DOMAIN VI WITH CALCIUM BOUND
Descriptor: CALCIUM ION, CALPAIN
Authors:Cygler, M, Blanchard, H, Grochulski, P.
Deposit date:1997-05-15
Release date:1998-05-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of a calpain Ca(2+)-binding domain reveals a novel EF-hand and Ca(2+)-induced conformational changes.
Nat.Struct.Biol., 4, 1997
3PVY
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BU of 3pvy by Molmil
The Phenylacetyl-CoA monooxygenase PaaAC subcomplex with coenzyme A
Descriptor: COENZYME A, GLYCEROL, Phenylacetic acid degradation protein paaA, ...
Authors:Cygler, M, Grishin, A.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2010-12-07
Release date:2011-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural and Functional Studies of the Escherichia coli Phenylacetyl-CoA Monooxygenase Complex.
J.Biol.Chem., 286, 2011
3PW1
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BU of 3pw1 by Molmil
The Phenylacetyl-CoA monooxygenase PaaAC subcomplex with phenylacetyl-CoA
Descriptor: GLYCEROL, Phenylacetic acid degradation protein paaA, Phenylacetic acid degradation protein paaC, ...
Authors:Cygler, M, Grishin, A.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2010-12-07
Release date:2011-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural and Functional Studies of the Escherichia coli Phenylacetyl-CoA Monooxygenase Complex.
J.Biol.Chem., 286, 2011
3PVT
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BU of 3pvt by Molmil
The Phenylacetyl-CoA monooxygenase PaaAC subcomplex with 3-hydroxybutanoyl-CoA
Descriptor: 3-HYDROXYBUTANOYL-COENZYME A, GLYCEROL, Phenylacetic acid degradation protein paaA, ...
Authors:Cygler, M, Grishin, A.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2010-12-07
Release date:2011-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structural and Functional Studies of the Escherichia coli Phenylacetyl-CoA Monooxygenase Complex.
J.Biol.Chem., 286, 2011
3PW8
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BU of 3pw8 by Molmil
The Phenylacetyl-CoA monooxygenase PaaAC subcomplex with acetyl-CoA
Descriptor: ACETYL COENZYME *A, Phenylacetic acid degradation protein paaA, Phenylacetic acid degradation protein paaC
Authors:Cygler, M, Grishin, A.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2010-12-07
Release date:2011-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Structural and Functional Studies of the Escherichia coli Phenylacetyl-CoA Monooxygenase Complex.
J.Biol.Chem., 286, 2011
3PWQ
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BU of 3pwq by Molmil
The Phenylacetyl-CoA monooxygenase PaaAC subcomplex
Descriptor: Phenylacetic acid degradation protein paaA, Phenylacetic acid degradation protein paaC
Authors:Cygler, M, Grishin, A.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2010-12-08
Release date:2011-01-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural and Functional Studies of the Escherichia coli Phenylacetyl-CoA Monooxygenase Complex.
J.Biol.Chem., 286, 2011
3PVR
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BU of 3pvr by Molmil
The Phenylacetyl-CoA monooxygenase PaaAC subcomplex with benzoyl-CoA
Descriptor: GLYCEROL, Phenylacetic acid degradation protein paaA, Phenylacetic acid degradation protein paaC, ...
Authors:Cygler, M, Grishin, A.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2010-12-07
Release date:2011-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Functional Studies of the Escherichia coli Phenylacetyl-CoA Monooxygenase Complex.
J.Biol.Chem., 286, 2011
1MFB
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BU of 1mfb by Molmil
HIGH RESOLUTION STRUCTURES OF ANTIBODY FAB FRAGMENT COMPLEXED WITH CELL-SURFACE OLIGOSACCHARIDE OF PATHOGENIC SALMONELLA
Descriptor: IGG1-LAMBDA SE155-4 FAB (HEAVY CHAIN), IGG1-LAMBDA SE155-4 FAB (LIGHT CHAIN), alpha-D-galactopyranose-(1-2)-alpha-D-mannopyranose-(1-4)-alpha-L-rhamnopyranose-(1-3)-alpha-D-galactopyranose-(1-2)-[alpha-D-Abequopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-alpha-L-rhamnopyranose
Authors:Zdanov, A, Cygler, M.
Deposit date:1993-10-25
Release date:1994-01-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Recognition of a carbohydrate antigenic determinant of Salmonella by an antibody.
Biochem.Soc.Trans., 21, 1993
1MFC
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BU of 1mfc by Molmil
HIGH RESOLUTION STRUCTURES OF ANTIBODY FAB FRAGMENT COMPLEXED WITH CELL-SURFACE OLIGOSACCHARIDE OF PATHOGENIC SALMONELLA
Descriptor: IGG1-LAMBDA SE155-4 FAB (HEAVY CHAIN), IGG1-LAMBDA SE155-4 FAB (LIGHT CHAIN), alpha-D-galactopyranose-(1-2)-[alpha-D-Abequopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-alpha-L-rhamnopyranose
Authors:Zdanov, A, Cygler, M.
Deposit date:1993-10-25
Release date:1994-01-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Recognition of a carbohydrate antigenic determinant of Salmonella by an antibody.
Biochem.Soc.Trans., 21, 1993
2FNI
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BU of 2fni by Molmil
PseC aminotransferase involved in pseudoaminic acid biosynthesis
Descriptor: PYRIDOXAL-5'-PHOSPHATE, aminotransferase
Authors:Cygler, M, Matte, A, Lunin, V.V, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2006-01-11
Release date:2006-01-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and Functional Characterization of PseC, an Aminotransferase Involved in the Biosynthesis of Pseudaminic Acid, an Essential Flagellar Modification in Helicobacter pylori
J.Biol.Chem., 281, 2006

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