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3O0A
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CRYSTAL STRUCTURE OF THE WILD TYPE CP1 HYDROLITIC DOMAIN FROM AQUIFEX AEOLICUS LEUCYL-TRNA
Descriptor:Leucyl-tRNA synthetase subunit alpha
Authors:Cura, V., Olieric, N., Wang, E.-D., Moras, D., Eriani, G., Cavarelli, J.
Deposit date:2010-07-19
Release date:2010-11-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Crystal Structure of the Wild Type and Two Mutants of the Cp1 Hydrolytic Domain from Aquifex Aeolicus Leucyl-tRNA Synthetase
To be Published
4C4A
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CRYSTAL STRUCTURE OF MOUSE PROTEIN ARGININE METHYLTRANSFERASE 7 IN COMPLEX WITH SAH
Descriptor:PROTEIN ARGININE N-METHYLTRANSFERASE 7, S-ADENOSYL-L-HOMOCYSTEINE, 3-[BENZYL(DIMETHYL)AMMONIO]PROPANE-1-SULFONATE, ...
Authors:Cura, V., Troffer-Charlier, N., Bonnefond, L., Wurtz, J.M., Cavarelli, J.
Deposit date:2013-09-02
Release date:2014-07-02
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Insight Into Arginine Methylation by the Mouse Protein Arginine Methyltransferase 7: A Zinc Finger Freezes the Mimic of the Dimeric State Into a Single Active Site.
Acta Crystallogr.,Sect.D, 70, 2014
5FUB
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CRYSTAL STRUCTURE OF ZEBRAFISH PROTEIN ARGININE METHYLTRANSFERASE 2 CATALYTIC DOMAIN WITH SAH
Descriptor:PROTEIN ARGININE METHYLTRANSFERASE 2, S-ADENOSYL-L-HOMOCYSTEINE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Cura, V., Troffer-Charlier, N., Marechal, N., Bonnefond, L., Cavarelli, J.
Deposit date:2016-01-22
Release date:2016-11-09
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (1.997 Å)
Cite:Structural studies of protein arginine methyltransferase 2 reveal its interactions with potential substrates and inhibitors.
FEBS J., 284, 2017
5FUL
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CRYSTAL STRUCTURE OF MUS MUSCULUS PROTEIN ARGININE METHYLTRANSFERASE 2 WITH SAH
Descriptor:PROTEIN ARGININE N-METHYLTRANSFERASE 2, S-ADENOSYL-L-HOMOCYSTEINE, CALCIUM ION, ...
Authors:Cura, V., Troffer-Charlier, N., Marechal, N., Bonnefond, L., Cavarelli, J.
Deposit date:2016-01-27
Release date:2016-11-09
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural studies of protein arginine methyltransferase 2 reveal its interactions with potential substrates and inhibitors.
FEBS J., 284, 2017
5FWA
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CRYSTAL STRUCTURE OF MUS MUSCULUS PROTEIN ARGININE METHYLTRANSFERASE 2 WITH CP1
Descriptor:PROTEIN ARGININE N-METHYLTRANSFERASE 2, 9-(6-carbamimidamido-5,6-dideoxy-beta-D-ribo-hexofuranosyl)-9H-purin-6-amine, TETRAETHYLENE GLYCOL, ...
Authors:Cura, V., Troffer-Charlier, N., Marechal, N., Bonnefond, L., Cavarelli, J.
Deposit date:2016-02-16
Release date:2016-11-09
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural studies of protein arginine methyltransferase 2 reveal its interactions with potential substrates and inhibitors.
FEBS J., 284, 2017
5FWD
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CRYSTAL STRUCTURE OF MUS MUSCULUS PROTEIN ARGININE METHYLTRANSFERASE 2 WITH CP2
Descriptor:PROTEIN ARGININE N-METHYLTRANSFERASE 2, 9-(7-{[amino(iminio)methyl]amino}-5,6,7-trideoxy-beta-D-ribo-heptofuranosyl)-9H-purin-6-amine, TETRAETHYLENE GLYCOL, ...
Authors:Cura, V., Troffer-Charlier, N., Marechal, N., Bonnefond, L., Cavarelli, J.
Deposit date:2016-02-12
Release date:2017-03-01
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Studies of Protein Arginine Methyltransferase 2 Reveal its Interactions with Potential Substrates and Inhibitors.
FEBS J., 284, 2017
5G02
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CRYSTAL STRUCTURE OF ZEBRAFISH PROTEIN ARGININE METHYLTRANSFERASE 2 WITH SFG
Descriptor:PROTEIN ARGININE METHYLTRANSFERASE 2, SINEFUNGIN, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Cura, V., Troffer-Charlier, N., Marechal, N., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-16
Release date:2016-11-09
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.451 Å)
Cite:Structural studies of protein arginine methyltransferase 2 reveal its interactions with potential substrates and inhibitors.
FEBS J., 284, 2017
5IH3
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH SAH AT 1.8 ANGSTROMS RESOLUTION
Descriptor:Histone-arginine methyltransferase CARM1, S-ADENOSYL-L-HOMOCYSTEINE, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-02-29
Release date:2017-03-29
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Crystal structure of mouse CARM1 in complex with SAH at 1.8 Angstroms resolution
To Be Published
5IS6
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH SINEFUNGIN AT 2.0 ANGSTROMS RESOLUTION
Descriptor:Histone-arginine methyltransferase CARM1, TETRAETHYLENE GLYCOL, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.007 Å)
Cite:Crystal structure of mouse CARM1 in complex with Sinefungin at 2.0 Angstroms resolution
To Be Published
5IS7
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH DECARBOXYLATED SAH
Descriptor:Histone-arginine methyltransferase CARM1, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Crystal structure of mouse CARM1 in complex with decarboxylated SAH
To Be Published
5IS8
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0271
Descriptor:Histone-arginine methyltransferase CARM1, 5'-{[(3S)-3-amino-3-carboxypropyl](2-chloroethyl)amino}-5'-deoxyadenosine, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.709 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor SA0271
To Be Published
5IS9
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0375
Descriptor:Histone-arginine methyltransferase CARM1, (2S)-2-amino-4-[(3-{4-[(2S)-2-amino-2-carboxyethyl]-1H-1,2,3-triazol-1-yl}propyl){[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}amino]butanoic acid (non-preferred name), 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor SA0375
To Be Published
5ISA
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0401
Descriptor:Histone-arginine methyltransferase CARM1, (2~{S})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-(3-azidopropyl)amino]-2-azanyl-butanoic acid, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor SA0401
To Be Published
5ISB
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0435
Descriptor:Histone-arginine methyltransferase CARM1, 5'-{[(3S)-3-amino-3-carboxypropyl][(1H-imidazol-4-yl)methyl]amino}-5'-deoxyadenosine, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor SA0435
To Be Published
5ISC
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0491
Descriptor:Histone-arginine methyltransferase CARM1, 5'-S-[(3S)-3-azaniumyl-3-carboxypropyl]-5'-thioadenosine, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor SA0491
To Be Published
5ISD
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0592
Descriptor:Histone-arginine methyltransferase CARM1, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor SA0592
To Be Published
5ISE
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0649
Descriptor:Histone-arginine methyltransferase CARM1, 5'-{[(3S)-3-amino-3-carboxypropyl](3-carbamimidamidopropyl)amino}-5'-deoxyadenosine, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of mouse CARM1 in complex with SAH at 1.8 Angstroms resolution
To Be Published
5ISF
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0705
Descriptor:Histone-arginine methyltransferase CARM1, 5'-{[(3S)-3-amino-3-carboxypropyl][2-(triazan-1-yl)ethyl]amino}-5'-deoxyadenosine, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor SA0705
To Be Published
5ISG
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0707
Descriptor:Histone-arginine methyltransferase CARM1, 1,2-DIMETHOXYETHANE, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.418 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor SA0707
To Be Published
5ISH
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0765
Descriptor:Histone-arginine methyltransferase CARM1, 5'-{1-[(3S)-3-amino-3-carboxypropyl]aziridin-1-ium-1-yl}-5'-deoxyadenosine, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.152 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor SA0765
To Be Published
5ISI
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0920 (5'-AMINO-5'-DEOXYADENOSINE)
Descriptor:Histone-arginine methyltransferase CARM1, 5'-amino-5'-deoxyadenosine, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:To be published
To Be Published
5JMQ
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CRYSTAL STRUCTURES OF A METHYL TRANSFERASE
Descriptor:Protein arginine N-methyltransferase 2, TETRAETHYLENE GLYCOL, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Troffer-Charlier, N., Marechal, N., Bonnefond, L., Cavarelli, J.
Deposit date:2016-04-29
Release date:2017-05-10
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (1.795 Å)
Cite:Crystal structures of PRMT2
To Be Published
5K8V
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CRYSTAL STRUCTURE OF MUS MUSCULUS PROTEIN ARGININE METHYLTRANSFERASE 4 (CARM1 130-487) WITH CP1
Descriptor:Histone-arginine methyltransferase CARM1, [[2-[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]ethylamino]-azanyl-methylidene]azanium, 1,2-DIMETHOXYETHANE, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-05-31
Release date:2016-11-09
Last modified:2017-01-18
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural studies of protein arginine methyltransferase 2 reveal its interactions with potential substrates and inhibitors.
FEBS J., 284, 2017
5K8W
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR U2
Descriptor:Histone-arginine methyltransferase CARM1, 9-(7-{[amino(iminio)methyl]amino}-5,6,7-trideoxy-beta-D-ribo-heptofuranosyl)-9H-purin-6-amine, 1,2-DIMETHOXYETHANE, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-05-31
Release date:2017-06-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor U2
To Be Published
5K8X
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR U3
Descriptor:Histone-arginine methyltransferase CARM1, [[[(~{E})-3-[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]prop-2-enyl]amino]-azanyl-methylidene]azanium, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-05-31
Release date:2017-06-21
Method:X-RAY DIFFRACTION (1.991 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor U3
To Be Published
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